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Research on Cross-Cultural Communication from the Perspective of Multiculturalism
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作者 Zhao Hongmei 《学术界》 CSSCI 北大核心 2020年第9期219-226,共8页
With the development of globalization,international exchanges in politics,economy and culture have become increasingly frequent.Accordingly,it is quite necessary and imperious for us to understand other cultures and i... With the development of globalization,international exchanges in politics,economy and culture have become increasingly frequent.Accordingly,it is quite necessary and imperious for us to understand other cultures and improve cross-cultural communicative competence.This essay aims to probe into the forms and characteristics of cross-cultural communication from the perspective of multiculturalism,and explore the strategies on how to achieve proper and effective cross-cultural communication. 展开更多
关键词 CULTURE MULTIculturalism COMMUNICATION cross-cultural communication cross-cultural communicative competence
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Multiculturalism Hiding in the Film:An Analysis of Welcome
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作者 孔紫菲 《海外英语》 2011年第11X期248-249,278,共3页
Multiculturalism is an inevitable topic facing with our daily life.A film may represent a society,culture,class,sexuality,and a multitude of things.Therefore films should be a very valuable object for studying culture... Multiculturalism is an inevitable topic facing with our daily life.A film may represent a society,culture,class,sexuality,and a multitude of things.Therefore films should be a very valuable object for studying culture in the world.In this paper,I would like to analyze the film Welcome to show the conflicts of different cultures and how multiculturalism present in movie.The purpose of this study is to view and discuss how multiculturalism has been depicted in this film. 展开更多
关键词 MULTIculturalism CULTURAL CONFLICT WELCOME
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The trend of tourism service integration and promotion from the perspective of multiculturalism
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作者 Shuangshuang Gong 《International Journal of Technology Management》 2017年第3期17-19,共3页
Multicultural education advocates the learning process and their own culture and experience together, advocating respect culture, advocate equality, difference and compensation, to set the multicultural curriculum, en... Multicultural education advocates the learning process and their own culture and experience together, advocating respect culture, advocate equality, difference and compensation, to set the multicultural curriculum, enhance the academic achievement of minority students and cultivate multicultural teachers' quality in three aspects as the starting point, the implementation of the education fair. Following the principle of equality, difference and compensation of education equality, its essence is to promote the equality of educational opportunities and provide a new angle of view and new measures for people to realize and implement educational equity. Multiculturalism is the main theme of today' s cultural development. It is both an opportunity and a challenge for the core values of the school. The cultivation of school core values under the impact of multi culture has adapted to the requirements of multicultural development, is conducive to re orientation of schools and reshaping the core values of teachers and students. From a multicultural perspective, it is helpful to promote the diversification of school core values from the perspectives of educational philosophy, organizational structure and cultural studies. The smaller scale of tourism enterprises in China, the lack of investment ability of enterprises and the low attention of tourists to the service quality of tourism have affected the development of tourism service innovation in our country. 展开更多
关键词 Multi culture angle of view integration of tourism services promotion trend
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Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites
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作者 Kirsty Goncalves Stefan Przyborski 《Neural Regeneration Research》 SCIE CAS 2025年第9期2645-2654,共10页
Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease.The accumulation of amyloid-βpeptides,a key hallmark of Alzheimer's disease,is be... Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease.The accumulation of amyloid-βpeptides,a key hallmark of Alzheimer's disease,is believed to induce neuritic abnormalities,including reduced growth,extension,and abnormal growth cone morphology,all of which contribute to decreased connectivity.However,the precise cellular and molecular mechanisms governing this response remain unknown.In this study,we used an innovative approach to demonstrate the effect of amyloid-βon neurite dynamics in both two-dimensional and three-dimensional cultu re systems,in order to provide more physiologically relevant culture geometry.We utilized various methodologies,including the addition of exogenous amyloid-βpeptides to the culture medium,growth substrate coating,and the utilization of human-induced pluripotent stem cell technology,to investigate the effect of endogenous amyloid-βsecretion on neurite outgrowth,thus paving the way for potential future applications in personalized medicine.Additionally,we also explore the involvement of the Nogo signaling cascade in amyloid-β-induced neurite inhibition.We demonstrate that inhibition of downstream ROCK and RhoA components of the Nogo signaling pathway,achieved through modulation with Y-27632(a ROCK inhibitor)and Ibuprofen(a Rho A inhibitor),respectively,can restore and even enhance neuronal connectivity in the presence of amyloid-β.In summary,this study not only presents a novel culture approach that offers insights into the biological process of neurite growth and inhibition,but also proposes a specific mechanism for reduced neural connectivity in the presence of amyloid-βpeptides,along with potential intervention points to restore neurite growth.Thereby,we aim to establish a culture system that has the potential to serve as an assay for measuring preclinical,predictive outcomes of drugs and their ability to promote neurite outgrowth,both generally and in a patient-specific manner. 展开更多
关键词 Alzheimer's disease induced pluripotent stem cell neurite outgrowth neuron NOGO Rho A ROCK stem cell three-dimensional culture
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Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development
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作者 Baoqi Hu Rui Wang +8 位作者 Hanyue Zhang Xiou Wang Sijia Zhou Bo Ma Yan Luan Xin Wang Xinlin Chen Zhichao Zhang Qianyan Kang 《Neural Regeneration Research》 SCIE CAS 2025年第3期900-912,共13页
The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.However,the lack of systematic and contin... The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.However,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development studies.Thus,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo retina.In this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in vivo.Initially,we used SOX2 and PAX6 immunostaining to identify retinal progenitor cells.We then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,respectively.Ki-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between groups.Additionally,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,respectively.The timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant retinas.Our study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina development.The findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation. 展开更多
关键词 bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells
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Neoliberal Multiculturalism and Western Exceptionalism: The Cultural Politics of the West
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作者 Sunera Thobani 《Fudan Journal of the Humanities and Social Sciences》 2018年第2期161-174,共14页
The tradition of the west defines its modernity as a radical rupture with endless possibilities for egalitarian futures; yet western modernity was rooted in the genocide of indigenous populations, transatlantic racial... The tradition of the west defines its modernity as a radical rupture with endless possibilities for egalitarian futures; yet western modernity was rooted in the genocide of indigenous populations, transatlantic racial slavery and colonialism. Moreover, as the war on terror demonstrates, racial/gender violence continues to be linked to the formation of western identity, culture and politics in the early twenty-first century. This paper examines how the histories of race and coloniality feature in the contemporary formation of the west, with a particular focus on US nationalism and Canadian multiculturalism. These nation-states are most often defined as antithetical, with the latter confirming that western society has transcended its originary racial/colonial politics. I begin with a brief discussion of the reformation of the west in the mid-twentieth century as the USA became the dominant western power. I then move to compare the contemporary national politics of the USA and Canada to highlight the divergence and convergence in their ddineation of their identity and values. My study demonstrates that although the white supremacist discourse that presently constitutes US nationalism is at variance with the multi- culturalism that shapes Canadian identity, these discourses can be defined as twin aspects of the racial/colonial politics that continue to give meaning to the idea of the west. 展开更多
关键词 West Cultural politics RACE Settler colonialism War on terror Muslims
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中国古代槟榔文化的接受与传播
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作者 冯青 《农业考古》 北大核心 2024年第4期195-201,共7页
作为舶来品的槟榔,在饮食、医药、赋税等方面扮演过重要的角色,具有丰厚的历史文化。梳理文献发现,两汉三国时期,槟榔视作“奇草异木”记载在各种《异物志》中,开始被接受;南北朝时期,槟榔是贵族士宦的“奢侈品”,唐代受佛教平等思想影... 作为舶来品的槟榔,在饮食、医药、赋税等方面扮演过重要的角色,具有丰厚的历史文化。梳理文献发现,两汉三国时期,槟榔视作“奇草异木”记载在各种《异物志》中,开始被接受;南北朝时期,槟榔是贵族士宦的“奢侈品”,唐代受佛教平等思想影响日渐向大众传播,宋代逐渐成为百姓家的“寻常物”。槟榔之所以能被接受与传播,并在海南用于婚俗,是因其本身的物质文化之外,还与其因贵异而用于重要的人际礼仪、文人墨客极力推崇渲染和赋予了槟榔君子品格等精神文化有着莫大的关系。 展开更多
关键词 betel nut culture imported product ACCEPTANCE DISSEMINATION
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Aboveground carbon sequestration of Cunninghamia lanceolata forests:Magnitude and drivers 被引量:1
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作者 Chen Wang Shuguang Liu +3 位作者 Yu Zhu Andrew R.Smith Ying Ning Deming Deng 《Forest Ecosystems》 SCIE CSCD 2024年第1期32-41,共10页
Understanding the spatial variation,temporal changes,and their underlying driving forces of carbon sequestration in various forests is of great importance for understanding the carbon cycle and carbon management optio... Understanding the spatial variation,temporal changes,and their underlying driving forces of carbon sequestration in various forests is of great importance for understanding the carbon cycle and carbon management options.How carbon density and sequestration in various Cunninghamia lanceolata forests,extensively cultivated for timber production in subtropical China,vary with biodiversity,forest structure,environment,and cultural factors remain poorly explored,presenting a critical knowledge gap for realizing carbon sequestration supply potential through management.Based on a large-scale database of 449 permanent forest inventory plots,we quantified the spatial-temporal heterogeneity of aboveground carbon densities and carbon accumulation rates in Cunninghamia lanceolate forests in Hunan Province,China,and attributed the contributions of stand structure,environmental,and management factors to the heterogeneity using quantile age-sequence analysis,partial least squares path modeling(PLS-PM),and hot-spot analysis.The results showed lower values of carbon density and sequestration on average,in comparison with other forests in the same climate zone(i.e.,subtropics),with pronounced spatial and temporal variability.Specifically,quantile regression analysis using carbon accumulation rates along an age sequence showed large differences in carbon sequestration rates among underperformed and outperformed forests(0.50 and 1.80 Mg·ha^(-1)·yr^(-1)).PLS-PM demonstrated that maximum DBH and stand density were the main crucial drivers of aboveground carbon density from young to mature forests.Furthermore,species diversity and geotopographic factors were the significant factors causing the large discrepancy in aboveground carbon density change between low-and high-carbon-bearing forests.Hotspot analysis revealed the importance of culture attributes in shaping the geospatial patterns of carbon sequestration.Our work highlighted that retaining largesized DBH trees and increasing shade-tolerant tree species were important to enhance carbon sequestration in C.lanceolate forests. 展开更多
关键词 Carbon density Carbon accumulation rate Forest age Spatial variation Cultural influence
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Problem identification and revitalization strategies for the recovery and reconstruction of traditional villages in the Ms 6.8 Luding Earthquake 被引量:1
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作者 HUANG Chao QIU Jian +3 位作者 LIU Chun JIANG Rui ZHAO Chuanrong ZHANG Yi 《Journal of Mountain Science》 SCIE CSCD 2024年第2期361-379,共19页
Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarize... Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural heritage.Through a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction process.Traditional villages face the risk of declining or even loss of heritage value.In order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional villages.The research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process. 展开更多
关键词 Seismic hazard Decision making Traditional village Cultural heritage protection Post-earthquake recovery and reconstruction Revitalization strategy
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Preparation of lactic acid bacteria compound starter cultures based on pasting properties and its improvement of glutinous rice flour and dough 被引量:1
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作者 Dengyu Wang Linlin Liu +4 位作者 Bing Wang Wenjian Xie Yanguo Shi Na Zhang Hongchen Fan 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第4期2090-2101,共12页
The effects of 5 lactic acid bacteria(LAB)fermentation on the pasting properties of glutinous rice flour were compared,and suitable fermentation strains were selected based on the changes of viscosity,setback value,an... The effects of 5 lactic acid bacteria(LAB)fermentation on the pasting properties of glutinous rice flour were compared,and suitable fermentation strains were selected based on the changes of viscosity,setback value,and breakdown value to prepare LAB compound starter cultures.The results revealed that Latilactobacillus sakei HSD004 and Lacticaseibacillus rhamnosus HSD005 had apparent advantages in increasing the viscosity and reducing the setback and breakdown values of glutinous rice flour.In particular,the compound starter created using the two abovementioned LAB in the ratio of 3:1 had better performance than that using a single LAB in improving the pasting properties and increasing the water and oil absorption capacity of glutinous rice flour.Moreover,the gelatinization enthalpy of the fermented samples increased significantly.For frozen glutinous rice dough stored for 28 days,the viscoelasticity of frozen dough prepared by compound starter was better than that of control dough,and the freezable water content was lower than that of control dough.These results indicate that compound LAB fermentation is a promising technology in the glutinous rice-based food processing industry,which has significance for its application. 展开更多
关键词 Glutinous rice flour Glutinous rice dough Lactic acid bacteria compound starter cultures Pasting properties VISCOELASTICITY
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Eikenella corrodens isolated from pleural effusion:A case report 被引量:1
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作者 Zi-Cong Liang Hao Ouyang +5 位作者 Xue-Jing Song Jian-Xin Liang Wei-Hua Zheng Jian-Jun Chen Zheng-Gang Yin Sha-Yan Chen 《World Journal of Clinical Cases》 SCIE 2024年第18期3596-3602,共7页
BACKGROUND The bacterium Eikenella,classified as a gram-negative member of the phylum Proteobacteria,is distinguished by its rarity,corrosive nature,facultative anaerobic properties,and conditional pathogenicity.It re... BACKGROUND The bacterium Eikenella,classified as a gram-negative member of the phylum Proteobacteria,is distinguished by its rarity,corrosive nature,facultative anaerobic properties,and conditional pathogenicity.It represents the sole species within its genus-Eikenella corrodens(E.corrodens)-and can be found colonizing both human and animal oral and nasopharyngeal regions.Additionally,it occasionally inhabits the gastrointestinal or urogenital tracts.However,its slow growth rate can be attributed to its high nutritional requirements.However,there is an uneven distribution of construction and diagnostic capacity in China which poses undeniable challenges for the clinical examination and analysis of this case,especially in the basic hospitals.CASE SUMMARY Here we presented a case of empyema associated with E.corrodens infection in a 67-year-old male patient without any previous history of infectious diseases in our primary hospital in Dongguan district of China.The patient was admitted due to recurrent worsening cough,sputum production,and dyspnea for 3 d,which had persisted for over 20 years.Moreover,the patient experienced a onehour episode of unconsciousness.Upon admission,immediate comprehensive examinations were conducted on the patient which subsequently led to his admission to the intensive care unit.Meanwhile,the patient presented with drowsiness and profuse sweating along with bilateral conjunctival edema observed during initiation of non-invasive ventilation,suggesting empyema.A significant amount of coffee-colored malodorous pleural fluid was drained during the procedure above and sent to the laboratory department for inspection.Finally,laboratory culture results confirmed the presence of E.corrodens infection in the pleural fluid sample.The patient received antimicrobial therapy until died on day 22 in the hospital.CONCLUSION In this report,we presented a case of empyema associated with E.corrodens infection.Multiple courses of morphological examination,viable culture analysis,and biochemical identification revealed its difficulties in detecting distinctive characteristics,as well as a detection model worth promoting.It’s just that there were still certain deficiencies in terms of morphological assessment,biochemical identification,and drug susceptibility testing. 展开更多
关键词 Eikenella corrodens Pleural fluid MORPHOLOGY Viable culture Biochemical identification Case report
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Automatic Extraction Method of 3D Feature Guidelines for Complex Cultural Relic Surfaces Based on Point Cloud 被引量:1
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作者 GENG Yuxin ZHONG Ruofei +1 位作者 HUANG Yuqin SUN Haili 《Journal of Geodesy and Geoinformation Science》 CSCD 2024年第1期16-41,共26页
Cultural relics line graphic serves as a crucial form of traditional artifact information documentation,which is a simple and intuitive product with low cost of displaying compared with 3D models.Dimensionality reduct... Cultural relics line graphic serves as a crucial form of traditional artifact information documentation,which is a simple and intuitive product with low cost of displaying compared with 3D models.Dimensionality reduction is undoubtedly necessary for line drawings.However,most existing methods for artifact drawing rely on the principles of orthographic projection that always cannot avoid angle occlusion and data overlapping while the surface of cultural relics is complex.Therefore,conformal mapping was introduced as a dimensionality reduction way to compensate for the limitation of orthographic projection.Based on the given criteria for assessing surface complexity,this paper proposed a three-dimensional feature guideline extraction method for complex cultural relic surfaces.A 2D and 3D combined factor that measured the importance of points on describing surface features,vertex weight,was designed.Then the selection threshold for feature guideline extraction was determined based on the differences between vertex weight and shape index distributions.The feasibility and stability were verified through experiments conducted on real cultural relic surface data.Results demonstrated the ability of the method to address the challenges associated with the automatic generation of line drawings for complex surfaces.The extraction method and the obtained results will be useful for line graphic drawing,displaying and propaganda of cultural relics. 展开更多
关键词 point cloud conformal parameterization vertex weight surface mesh cultural relics feature extraction
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Natural Disaster Risk Monitoring for Immovable Cultural Relics Based on Digital Twin 被引量:1
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作者 LI Bolun DONG Youqiang +2 位作者 QIAO Yunfei HOU Miaole WEN Caihuan 《Journal of Geodesy and Geoinformation Science》 CSCD 2024年第1期90-104,共15页
Natural disaster risk monitoring is an important task for disaster prevention and reduction.In the case of immovable cultural relics,however,the feedback mechanism,risk factors,monitoring logic,and monitoring indicato... Natural disaster risk monitoring is an important task for disaster prevention and reduction.In the case of immovable cultural relics,however,the feedback mechanism,risk factors,monitoring logic,and monitoring indicators of natural disaster risk monitoring are complex.How to achieve intelligent perception and monitoring of natural disaster risk for immovable cultural relics has always been a focus and a challenge for researchers.Based on the analysis of the concepts and issues related to the natural disaster risk of immovable cultural relics,this paper proposes a framework for natural disaster risk monitoring for immovable cultural relics based on the digital twin.This framework focuses on risk monitoring,including the physical entities of natural disaster risk for immovable cultural relics,monitoring indicators,and virtual entity construction.A platform for monitoring the natural disaster risk of immovable cultural relics is proposed.Using the Puzhou Ancient City Site as a test bed,the proposed concept can be used for monitoring the natural disaster risk of immovable cultural relics at different scales. 展开更多
关键词 immovable cultural relics natural disaster risk digital twin risk monitoring
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Between the City and Images:An Analysis of Mainstream Media’s Paths of Constructing the Cultural Memory of a City:Taking Chengdu Radio and Television’s“Hi Chengdu”as an Example 被引量:1
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作者 Ding Ran Shi Lei 《Contemporary Social Sciences》 2024年第2期97-111,共15页
Mainstream media play a crucial role in constructing the cultural memory of a city.This study used 319 short videos released by“Hi Chengdu,”a new media product of Chengdu Radio and Television,as samples.Based on the... Mainstream media play a crucial role in constructing the cultural memory of a city.This study used 319 short videos released by“Hi Chengdu,”a new media product of Chengdu Radio and Television,as samples.Based on the grounded theory,a research framework encompassing“content,technology,and discourse”was established to explore the paths through which mainstream media construct the cultural memory.Regarding content,this paper emphasized temporal and spatial contexts and urban spaces,delving deep into the themes of the cultural memory and vehicles for it.In terms of technology,this paper discussed the practice of leveraging audio/visual-mode discourse to stitch together the impressions of a city and evoke emotional resonance to create a“flow”of memory.As for discourse,this paper looked at the performance of a communication ritual to frame concepts and shape urban identity.It is essential to break free from conventional thinking and leverage local culture as the primary driving force to further boost a city’s productivity,in order to excel in cultural communication. 展开更多
关键词 the cultural memory of a city short videos the grounded theory Chengdu Radio and Television “Hi Chengdu”
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跨文化视域下的雍古艺术——《成为艺术:探索跨文化范畴》评介
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作者 张鑫 《美育学刊》 2024年第5期I0005-I0005,共1页
澳大利亚人类学家霍华德·墨菲(Howard Morphy)的《成为艺术:探索跨文化范畴》(Becoming Art:Exploring Cross-culture Categories)一书以澳大利亚阿纳姆地区的雍古艺术为研究对象,从时间线上梳理了雍古艺术的历史发展脉络,并从人... 澳大利亚人类学家霍华德·墨菲(Howard Morphy)的《成为艺术:探索跨文化范畴》(Becoming Art:Exploring Cross-culture Categories)一书以澳大利亚阿纳姆地区的雍古艺术为研究对象,从时间线上梳理了雍古艺术的历史发展脉络,并从人类学的角度对雍古艺术的社会功能、文化内涵、审美形式等具体问题进行了阐释。在方法论上,因不满于阿尔弗雷德·盖尔(Alfred Gell)将审美因素排除在艺术人类学领域之外的做法,墨菲在其雍古艺术史研究中采取了语义学维度与美学维度相结合的路径,并坚持认为审美因素是艺术品与其他物品区别开来的关键因素。 展开更多
关键词 文化范畴 跨文化视域 culture 阿尔弗雷德 人类学领域 审美因素 美学维度 阿纳姆
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Anticancer Activity of Rice Callus Suspension Cultures from Aromatic Varieties and Metabolites Regulated in Treated Cancer Cell Lines
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作者 Anuradha KUMARI Wusirika RAMAKRISHNA 《Rice science》 SCIE CSCD 2024年第4期449-462,I0027-I0030,共18页
Tissue culture techniques were used to produce large amounts of bioactive compounds with medicinal potential, overcoming space and time constraints for cancer prevention. Rice callus suspension cultures(RCSC) and seed... Tissue culture techniques were used to produce large amounts of bioactive compounds with medicinal potential, overcoming space and time constraints for cancer prevention. Rice callus suspension cultures(RCSC) and seed extracts prepared from aromatic rice varieties were used to evaluate the cytotoxic impact on human colon and lung cancer cell lines, as well as a normal control cell line, using Taxol as a positive control. RCSC and seed extracts from two Indian aromatic rice varieties were applied at different concentrations to treat the cancer cell lines and normal lung fibroblasts over varying time intervals. Apoptosis was assessed in 1:5 dilutions of the A549 and HT-29 cell lines treated with RCSC for 72 h, using propidium iodide staining and flow cytometry. RCSC showed a more potent cytotoxic effect than seed extracts with minimal effect on the normal cell line, in contrast to Taxol. Confocal microscopy and flow cytometry further confirmed the apoptotic effect of RCSC. Gas chromatography-mass spectrometry-based metabolic profiling identified metabolites involved in cytotoxicity and highlighted altered pathways. RCSC is proposed as an alternative source for the development of novel anticancer drugs with reduced side effects. 展开更多
关键词 ANTICANCER CYTOTOXICITY metabolite profiling plant tissue culture rice callus suspension culture secondary metabolite
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Brain dysfunctions and neurotoxicity induced by psychostimulants in experimental models and humans:an overview of recent findings
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作者 Marcello Serra Nicola Simola +1 位作者 Alexia E.Pollack Giulia Costa 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第9期1908-1918,共11页
Preclinical and clinical studies indicate that psychostimulants,in addition to having abuse potential,may elicit brain dysfunctions and/or neurotoxic effects.Central toxicity induced by psychostimulants may pose serio... Preclinical and clinical studies indicate that psychostimulants,in addition to having abuse potential,may elicit brain dysfunctions and/or neurotoxic effects.Central toxicity induced by psychostimulants may pose serious health risks since the recreational use of these substances is on the rise among young people and adults.The present review provides an overview of recent research,conducted between 2018 and 2023,focusing on brain dysfunctions and neurotoxic effects elicited in experimental models and humans by amphetamine,cocaine,methamphetamine,3,4-methylenedioxymethamphetamine,methylphenidate,caffeine,and nicotine.Detailed elucidation of factors and mechanisms that underlie psychostimulant-induced brain dysfunction and neurotoxicity is crucial for understanding the acute and enduring noxious brain effects that may occur in individuals who use psychostimulants for recreational and/or therapeutic purposes. 展开更多
关键词 3 4-methylenedioxymethamphetamine AMPHETAMINE caffeine cell cultures cocaine METHAMPHETAMINE METHYLPHENIDATE NEUROTOXICITY nicotine
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Analysis of the Reform of Ideological and Political Education in College English Curriculum from the Perspective of“Cultural Confidence” 被引量:1
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作者 Hui Zhang 《Journal of Contemporary Educational Research》 2024年第2期117-122,共6页
With the rapid development of the education industry,higher requirements have been put forward for college English education and teaching,accelerating the pace of college English reform.Issues such as how to integrate... With the rapid development of the education industry,higher requirements have been put forward for college English education and teaching,accelerating the pace of college English reform.Issues such as how to integrate knowledge transmission,language expression skill improvement,cultural element extraction,and ideological and political education,and present the role of curriculum education function have attracted attention.In the era of informatization,college students’thinking has undergone certain changes and gradually developed towards diversification.Therefore,universities should start from the perspective of cultural confidence,extract valuable ideological and political elements,and explore effective tourism ideological and political teaching methods.While helping college students enhance their cultural confidence,it is also beneficial for them to better inherit traditional Chinese culture.This article conducts an in-depth exploration of ideological and political education in college English courses from the perspective of“cultural confidence”and uses scientific and effective measures to solve the problems encountered,aiming to provide valuable guidelines for relevant researchers. 展开更多
关键词 Cultural confidence College English teaching Course ideological and political education MEASURE
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Effects of Different Culture Conditions and Growth States on the Structure and Hemostatic Properties of Coscinodiscus sp.
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作者 HE Zheng LI Qinfeng +4 位作者 LIU Jinfeng HUI Guangyan FENG Chao CHENG Xiaojie CHEN Xiguang 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第4期1121-1134,共14页
As a renewable marine inorganic material,Coscinodiscus sp.has significant potential in the field of rapid hemostasis.However,the low yield of Coscinodiscus sp.seriously limits the application.In this study,two new cul... As a renewable marine inorganic material,Coscinodiscus sp.has significant potential in the field of rapid hemostasis.However,the low yield of Coscinodiscus sp.seriously limits the application.In this study,two new culture modes were adopted to increase the production of Coscinodiscus sp.,the effect of changes in culture conditions and growth status on the hemostatic activity of diatoms was detected.To prevent Coscinodiscus sp.from sinking in culture,the suspension culture mode was realized by adding0.5%agar.The semi-continuous high nutrient concentration culture mode increased the cell density of Coscinodiscus sp.to 11000cells mL^(-1)and shorten the culture cycle to 5 d.In terms of coagulation activity,the addition of frustules reduced the in vitro coagulation time by half and the activation time of coagulation by 70%.The hemolysis rate and cytotoxicity of frustules harvested in the two culture modes did not change significantly.The results showed that suspension culture mode and high nutrient concentration culture mode only changed the growth state of Coscinodiscus sp.,while the hemostatic performance remained stable. 展开更多
关键词 diatom culture Coscinodiscus sp frustule hemostatic material hemorrhage control
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Evaluation of ruminal methane and ammonia formation and microbiota composition as affected by supplements based on mixtures of tannins and essential oils using Rusitec
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作者 Giulia Foggi Melissa Terranova +9 位作者 Matteo Daghio Sergej L.Amelchanka Giuseppe Conte Simon Ineichen Monica Agnolucci Carlo Viti Alberto Mantino Arianna Buccioni Michael Kreuzer Marcello Mele 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第4期1607-1622,共16页
Background Dietary supplements based on tannin extracts or essential oil compounds(EOC)have been repeatedly reported as a promising feeding strategy to reduce the environmental impact of ruminant husbandry.A previous ... Background Dietary supplements based on tannin extracts or essential oil compounds(EOC)have been repeatedly reported as a promising feeding strategy to reduce the environmental impact of ruminant husbandry.A previous batch culture screening of various supplements identified selected mixtures with an enhanced potential to mitigate ruminal methane and ammonia formation.Among these,Q-2(named after quebracho extract and EOC blend 2,composed of carvacrol,thymol,and eugenol)and C-10(chestnut extract and EOC blend 10,consisting of oregano and thyme essential oils and limonene)have been investigated in detail in the present study with the semi-continuous rumen simulation technique(Rusitec)in three independent runs.For this purpose,Q-2 and C-10,dosed according to the previous study,were compared with a non-supplemented diet(negative control,NC)and with one supplemented with the commercial EOC-based Agolin^(R) Ruminant(positive control,PC).Results From d 5 to 10 of fermentation incubation liquid was collected and analysed for pH,ammonia,protozoa count,and gas composition.Feed residues were collected for the determination of ruminal degradability.On d 10,samples of incubation liquid were also characterised for bacterial,archaeal and fungal communities by high-throughput sequencing of 16S rRNA and 26S ribosomal large subunit gene amplicons.Regardless of the duration of the fermentation period,Q-2 and C-10 were similarly efficient as PC in mitigating either ammonia(-37%by Q-2,-34%by PC)or methane formation(-12%by C-10,-12%by PC).The PC was also responsible for lower feed degradability and bacterial and fungal richness,whereas Q-2 and C-10 effects,particularly on microbiome diversities,were limited compared to NC.Conclusions All additives showed the potential to mitigate methane or ammonia formation,or both,in vitro over a period of 10 d.However,several differences occurred between PC and Q-2/C-10,indicating different mechanisms of action.The pronounced defaunation caused by PC and its suggested consequences apparently determined at least part of the mitigant effects.Although the depressive effect on NDF degradability caused by Q-2 and C-10 might partially explain their mitigation properties,their mechanisms of action remain mostly to be elucidated. 展开更多
关键词 Additive Bacteria Continuous culture DEGRADABILITY Fermentation Fungi Greenhouse gas In vitro Microbiome RUMEN
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