In the present study, we examined the analgesic effect of repeated electroacupuncture at bilateral Zusanfi （ST36） and Yanglingquan （GB34） once a day for 14 consecutive days in a rat model of chronic sciatic nerve ...In the present study, we examined the analgesic effect of repeated electroacupuncture at bilateral Zusanfi （ST36） and Yanglingquan （GB34） once a day for 14 consecutive days in a rat model of chronic sciatic nerve constriction injury-induced neuropathic pain. In addition, concomitant changes in calcium/calmodulin-dependent protein kinase II expression and synaptic ultrastructure of neurons in the hippocampal CA3 region were examined. The thermal pain threshold （paw withdrawal latency） was increased significantly in both groups at 2 weeks after electroacupuncture intervention compared with 2 days of electroacupuncture. In ovariectomized rats with chronic constriction injury, the analgesic effect was significantly reduced. Electroacupuncture for 2 weeks significantly diminished the injury-induced increase in synaptJc cleft width and thinning of the postsynaptJc density, and it significantly suppressed the down-regulation of intracellular calcium/ calmodulin-dependent protein kinase II expression in the hippocampal CA3 region. Repeated electroacupuncture intervention had a cumulative analgesic effect on injury-induced neuropathic pain reactions, and it led to synaptic remodeling of hippocampal neurons and upregulated calcium/calmodulin-dependent protein kJnase II expression in the hippocampal CA3 region.展开更多
A joint estimation algorithm of direction of arrival （DOA）, frequency, and polarization, based on fourth-order cumulants and uniform circular array （UCA） of trimmed vector sensors is presented for narrowband non-G...A joint estimation algorithm of direction of arrival （DOA）, frequency, and polarization, based on fourth-order cumulants and uniform circular array （UCA） of trimmed vector sensors is presented for narrowband non-Gaussian signals. The proposed approach, which is suitable for applications in arbitrary Gaussian noise environments, gives a closed-form representation of the estimated parameters, without spectral peak searching. An efficient method is also provided for elimination of cyclic phase ambiguities. Simulations are presented to show the performance of the algorithm.展开更多
In this paper, the problem of estimating the direction of arrival of signals of which some may be perfectly correlated is considered. This method can be applied in the situation that the non-Gaussian independent and c...In this paper, the problem of estimating the direction of arrival of signals of which some may be perfectly correlated is considered. This method can be applied in the situation that the non-Gaussian independent and coherent signals coexist with unknown Gaussian noise. In this method at first via mappings, the virtual uniform linear array (ULA) and also the shifted versions of this virtual ULA by assuming that all the DOAs are located in one section are constructed. In order to avoid coloring the noise because of these mappings we use a cumulant matrix instead of a covariance ones. In this method since we construct all the subarrays virtually for detection of coherent signals we do not need the array with regular configuration. The advantages of this method are: increasing the array aperture, having the ability to find the DOAs with fewer sensors and also avoiding the coupling between sensors as much as possible in contrast to conventional spatial smoothing.展开更多
An array extension method in a noisy environment was proposed to improve angular resolution and array gain. The proposed method combines the FOC （fourth-order cumulants） technique with the ETAM （extended towed arra...An array extension method in a noisy environment was proposed to improve angular resolution and array gain. The proposed method combines the FOC （fourth-order cumulants） technique with the ETAM （extended towed array measurements） method to extend array aperture and suppress Gaussian noise, First, successive measurements of a virtual uniform linear array were constructed by applying lburth-order cumulants to measurements of uniform linear array; Gaussian noise in these measurements was also eliminated. Then, the array was extended by compensating phase differences using the ETAM method, Finally, the synthetic aperture was extended further by the fourth-order cumulants technique. The proposed FOC-ETAM-FOC method not only improves angular resolution and array gain, but also effectively suppresses Gaussian noise. Furthermore, it inherits the advantages of the ETAM method. Simulation results showed that the FOC-ETAM-FOC method achieved better angular resolution and array gain than the ETAM method. Furthermore this method outperforms the ETAM method in Gaussian noise environment.展开更多
A cumulant-based beamforing technique for synchronous CDMA system with decorrelator is presented. With decorrelating detector the proposed algorithm has the advantages that the steering vector of desired user’s can b...A cumulant-based beamforing technique for synchronous CDMA system with decorrelator is presented. With decorrelating detector the proposed algorithm has the advantages that the steering vector of desired user’s can be estimated independently by eliminating all the other resolved signal interferences. Furthermore employing cumulant-based signal processing technique the steering vector of the decoupled signals can be estimated blindly. Simulation results show that the cumulant-based beamformer demonstrates excellent performance.展开更多
This paper gives a MUSIC signal DOA estimation algorithm based on the modified high-order cumulant matrix which is constructed by the recieved data and their conjugate rearrangements. When the snapshot number is limit...This paper gives a MUSIC signal DOA estimation algorithm based on the modified high-order cumulant matrix which is constructed by the recieved data and their conjugate rearrangements. When the snapshot number is limited, this algorithm can improve the signal DOA estimation performances obviously, and its computational complexity scarcely increases. Finally, some simulation results to verify the theoretical analyses are presented.展开更多
The Directions of Arrivals （DOAs）, speeds and distances of targets are all required for array signal processing. Based on the periodic phase shift of coherent pulse sequence waveform, a new estimation of multi-targ...The Directions of Arrivals （DOAs）, speeds and distances of targets are all required for array signal processing. Based on the periodic phase shift of coherent pulse sequence waveform, a new estimation of multi-targets＇ 2-Dimentional （2-D） DOA angle, Doppler frequency shift and relative time-delay is proposed. Based on a virtual sensor array constructed by pulse cumulating, the estinaations of azimuth, elevation, Doppler frequency shift and time-delay can be obtained simultaneously, and the least number of pulses could be two. This method is computationally efficient even in heavier noised environment, and all estimations are automatically paired in calculation process with no used to any plane sensor array and deal with many spectrum searching. Further more, this algorithm can be targets at the same time only by few sensors. The targets number that can deal with simultaneously is several times to the sensor number, which is the upper limit for normal algorithms such as ESPRIT and MUSIC. These characteristics would be very useful, especially, for aerial systems. Simulations demonstrate the capabilities of this method efficiently.展开更多
The fourth-order cumulant of zero mean Gaussian distribution noise always equals to zero theoretically. In practice the probability density of noise and reverberation is the key problem to performance of the fourth-or...The fourth-order cumulant of zero mean Gaussian distribution noise always equals to zero theoretically. In practice the probability density of noise and reverberation is the key problem to performance of the fourth-order cumulant beamforming technique. In this paper, the array gain functions of the fourth-order cumulant beamforming are deducted considering the instantaneous amplitude distribution of the ambient sea noise and bottom reverberation respectively. And the relationships are determined between array gain and the factors including the number of the array elements, the fourth-order and second-order statistical properties of the noise and reverberation, and the input signal-to-noise ratio. It is also verified that there is a critical signal-to-interference ratio and the fourth-order cumulant beamforming can obtain higher gain and resolution than the conventional beamforming method when the ratio is larger than it. The results of experiment data processing demonstrate that the gain and the resolution of the fourth-order cumulant beamforming coincide with the theoretic.展开更多
A polynomial-rooting based fourth-order cumulant algorithm is presented for direction-of-arrival（DOA） estimation of second-order fully noncircular source signals, using a uniform linear array（ULA）. This algorithm ...A polynomial-rooting based fourth-order cumulant algorithm is presented for direction-of-arrival（DOA） estimation of second-order fully noncircular source signals, using a uniform linear array（ULA）. This algorithm inherits all merits of its spectralsearching counterpart except for the applicability to arbitrary array geometry, while reducing considerably the computation cost.Simulation results show that the proposed algorithm outperforms the previously developed closed-form second-order noncircular ESPRIT method, in terms of processing capacity and DOA estimation accuracy, especially in the presence of spatially colored noise.展开更多
This paper proposes a new algorithm for joint frequency, two-dimensional （2-D） directions-of-arrival （DOA）, and polarization estimation using parallel factor （PARAFAC） analysis model and cumulant. The proposed a...This paper proposes a new algorithm for joint frequency, two-dimensional （2-D） directions-of-arrival （DOA）, and polarization estimation using parallel factor （PARAFAC） analysis model and cumulant. The proposed algorithm designs a new array configuration, and extends the PARAFAC analysis model from the common data-domain and subspace-domain to the cumulant one, and forms three-way arrays by using the three cumulant matrices obtained from the properly chosen dipole outputs, and analyzes the uniqueness of low-rank decomposition of the three-way arrays, and then jointly estimates the source parameters via the low-rank decomposition of the constructed PARAFAC model. In comparison with the conventional methods, the proposed method alleviates the aperture loss, and avoids pairing parameter. Finally, the simulation results are presented to validate the performance of the proposed method.展开更多
基金supported by the National Natural Science Foundation of China,No.30472241,90709031 and 30973796the Ministry of Science and Technology of China("973"Project),No.2007CB512505+1 种基金provided by the Foundation of Hainan Province,No.310054the Health Department of Hainan Province,Qiong-Wei-45
文摘In the present study, we examined the analgesic effect of repeated electroacupuncture at bilateral Zusanfi （ST36） and Yanglingquan （GB34） once a day for 14 consecutive days in a rat model of chronic sciatic nerve constriction injury-induced neuropathic pain. In addition, concomitant changes in calcium/calmodulin-dependent protein kinase II expression and synaptic ultrastructure of neurons in the hippocampal CA3 region were examined. The thermal pain threshold （paw withdrawal latency） was increased significantly in both groups at 2 weeks after electroacupuncture intervention compared with 2 days of electroacupuncture. In ovariectomized rats with chronic constriction injury, the analgesic effect was significantly reduced. Electroacupuncture for 2 weeks significantly diminished the injury-induced increase in synaptJc cleft width and thinning of the postsynaptJc density, and it significantly suppressed the down-regulation of intracellular calcium/ calmodulin-dependent protein kinase II expression in the hippocampal CA3 region. Repeated electroacupuncture intervention had a cumulative analgesic effect on injury-induced neuropathic pain reactions, and it led to synaptic remodeling of hippocampal neurons and upregulated calcium/calmodulin-dependent protein kJnase II expression in the hippocampal CA3 region.
基金This project was supported by the Graduate Innovation Laboratory of Jilin University(502039)Jilin Science Committee of China(20030519)+1 种基金the National Natural Science Foundation of China (69872012)the Foundation of Nanjing Institute of Technology.
文摘A joint estimation algorithm of direction of arrival （DOA）, frequency, and polarization, based on fourth-order cumulants and uniform circular array （UCA） of trimmed vector sensors is presented for narrowband non-Gaussian signals. The proposed approach, which is suitable for applications in arbitrary Gaussian noise environments, gives a closed-form representation of the estimated parameters, without spectral peak searching. An efficient method is also provided for elimination of cyclic phase ambiguities. Simulations are presented to show the performance of the algorithm.
文摘In this paper, the problem of estimating the direction of arrival of signals of which some may be perfectly correlated is considered. This method can be applied in the situation that the non-Gaussian independent and coherent signals coexist with unknown Gaussian noise. In this method at first via mappings, the virtual uniform linear array (ULA) and also the shifted versions of this virtual ULA by assuming that all the DOAs are located in one section are constructed. In order to avoid coloring the noise because of these mappings we use a cumulant matrix instead of a covariance ones. In this method since we construct all the subarrays virtually for detection of coherent signals we do not need the array with regular configuration. The advantages of this method are: increasing the array aperture, having the ability to find the DOAs with fewer sensors and also avoiding the coupling between sensors as much as possible in contrast to conventional spatial smoothing.
基金Supported by the National Science Foundation of China (No.60872146)
文摘An array extension method in a noisy environment was proposed to improve angular resolution and array gain. The proposed method combines the FOC （fourth-order cumulants） technique with the ETAM （extended towed array measurements） method to extend array aperture and suppress Gaussian noise, First, successive measurements of a virtual uniform linear array were constructed by applying lburth-order cumulants to measurements of uniform linear array; Gaussian noise in these measurements was also eliminated. Then, the array was extended by compensating phase differences using the ETAM method, Finally, the synthetic aperture was extended further by the fourth-order cumulants technique. The proposed FOC-ETAM-FOC method not only improves angular resolution and array gain, but also effectively suppresses Gaussian noise. Furthermore, it inherits the advantages of the ETAM method. Simulation results showed that the FOC-ETAM-FOC method achieved better angular resolution and array gain than the ETAM method. Furthermore this method outperforms the ETAM method in Gaussian noise environment.
文摘A cumulant-based beamforing technique for synchronous CDMA system with decorrelator is presented. With decorrelating detector the proposed algorithm has the advantages that the steering vector of desired user’s can be estimated independently by eliminating all the other resolved signal interferences. Furthermore employing cumulant-based signal processing technique the steering vector of the decoupled signals can be estimated blindly. Simulation results show that the cumulant-based beamformer demonstrates excellent performance.
文摘This paper gives a MUSIC signal DOA estimation algorithm based on the modified high-order cumulant matrix which is constructed by the recieved data and their conjugate rearrangements. When the snapshot number is limited, this algorithm can improve the signal DOA estimation performances obviously, and its computational complexity scarcely increases. Finally, some simulation results to verify the theoretical analyses are presented.
基金Supported by the NWPU Graduate Innovation Lab Cen-ter of China (No.04029)
文摘The Directions of Arrivals （DOAs）, speeds and distances of targets are all required for array signal processing. Based on the periodic phase shift of coherent pulse sequence waveform, a new estimation of multi-targets＇ 2-Dimentional （2-D） DOA angle, Doppler frequency shift and relative time-delay is proposed. Based on a virtual sensor array constructed by pulse cumulating, the estinaations of azimuth, elevation, Doppler frequency shift and time-delay can be obtained simultaneously, and the least number of pulses could be two. This method is computationally efficient even in heavier noised environment, and all estimations are automatically paired in calculation process with no used to any plane sensor array and deal with many spectrum searching. Further more, this algorithm can be targets at the same time only by few sensors. The targets number that can deal with simultaneously is several times to the sensor number, which is the upper limit for normal algorithms such as ESPRIT and MUSIC. These characteristics would be very useful, especially, for aerial systems. Simulations demonstrate the capabilities of this method efficiently.
基金supported by the national Natural Science Foundation of China(51279033)the Natural Science Foundation of Heilongjiang Province,China(F201346)
文摘The fourth-order cumulant of zero mean Gaussian distribution noise always equals to zero theoretically. In practice the probability density of noise and reverberation is the key problem to performance of the fourth-order cumulant beamforming technique. In this paper, the array gain functions of the fourth-order cumulant beamforming are deducted considering the instantaneous amplitude distribution of the ambient sea noise and bottom reverberation respectively. And the relationships are determined between array gain and the factors including the number of the array elements, the fourth-order and second-order statistical properties of the noise and reverberation, and the input signal-to-noise ratio. It is also verified that there is a critical signal-to-interference ratio and the fourth-order cumulant beamforming can obtain higher gain and resolution than the conventional beamforming method when the ratio is larger than it. The results of experiment data processing demonstrate that the gain and the resolution of the fourth-order cumulant beamforming coincide with the theoretic.
基金supported by the National Natural Science Foundation of China(617020986170209961331019)
文摘A polynomial-rooting based fourth-order cumulant algorithm is presented for direction-of-arrival（DOA） estimation of second-order fully noncircular source signals, using a uniform linear array（ULA）. This algorithm inherits all merits of its spectralsearching counterpart except for the applicability to arbitrary array geometry, while reducing considerably the computation cost.Simulation results show that the proposed algorithm outperforms the previously developed closed-form second-order noncircular ESPRIT method, in terms of processing capacity and DOA estimation accuracy, especially in the presence of spatially colored noise.
基金Supported by the National Natural Science Foundation of China (Grant No. 60901059/F0103)the Educational Department Foundations of Shaanxi Province (Grant No. 09JK629)the Doctor Research Start Fund of Xi’an University of Technology (Grant No. 116-210903)
文摘This paper proposes a new algorithm for joint frequency, two-dimensional （2-D） directions-of-arrival （DOA）, and polarization estimation using parallel factor （PARAFAC） analysis model and cumulant. The proposed algorithm designs a new array configuration, and extends the PARAFAC analysis model from the common data-domain and subspace-domain to the cumulant one, and forms three-way arrays by using the three cumulant matrices obtained from the properly chosen dipole outputs, and analyzes the uniqueness of low-rank decomposition of the three-way arrays, and then jointly estimates the source parameters via the low-rank decomposition of the constructed PARAFAC model. In comparison with the conventional methods, the proposed method alleviates the aperture loss, and avoids pairing parameter. Finally, the simulation results are presented to validate the performance of the proposed method.
