To determine the sensitivity and specificity of using a computer photoscreener and non cycloplegic retinoscopy in the detection of amblyopiogenic factors in nine to fifty months old infants and children Methods Th...To determine the sensitivity and specificity of using a computer photoscreener and non cycloplegic retinoscopy in the detection of amblyopiogenic factors in nine to fifty months old infants and children Methods Three hundred children, nine to fifty months old, were screened with the computer photoscreener and non cycloplegic retinoscopy With a blinded standardized clinical assessment as the standard, an overall comparison of the sensitivity of and specificity results obtained with the two techniques was made Photoscreen images on the computer monitor screen were reviewed and analyzed immediately by two independent observers for indicators of amblyopiogenic risk factors Simultaneously, the results were compared to the findings of a full ophthalmologic examination Results The computer photoscreener revealed a sensitivity of 94 6% and specificity of 90 1%, and the non cycloplegic retinocopy revealed a sensitivity of 85 7% and specificity of 81 0% for the detection of amblyopiogenic risk factors, including hyperopia (+2 75 D or more), myopia (-1 50 D or more), astigmatism (1 75 D or more), anisometropia (2 00 D or more), ocular misalignment (5 degrees or more), and media opacity (1 5?mm or more) Conclusions The computer photoscreener offers an opportunity to identify problems that limit vision, and could provide a feasible and sufficiently reliable screening technique in infants and preschool children to be screened successfully for amblyopiogenic risk factors展开更多
AIM: To study the evolution of the refractive status and examine the affected factors in infants during the first year of life in a large sample size in China. METHODS: A total of 1258 babies (2516 eyes) aged 32w...AIM: To study the evolution of the refractive status and examine the affected factors in infants during the first year of life in a large sample size in China. METHODS: A total of 1258 babies (2516 eyes) aged 32wk gestational age to ty participated in the study, including 766 premature and 492 full-term infants. First, each baby received an orthoptic examination, slit-lamp checking and fundus imaging. Patients with diseases which might affect refractive status were excluded from the cohort. The cycloplegia retinoscopy was performed. Their neonatal histories were reviewed. Each measurement contained the refractive status and calculation of the spherical equivalent (SE). RESULTS: Refractive state showed an average hyperopia of +0.94_+1.63 D at early ages, followed by a trend toward more hyperopia. The refractive state reached the top (+2.431.46 D) at the age of one to two months. Then gliding till one year old when the refractive state reached +0.59:1.41 D. The prevalence of astigmatism was 42.17% in the study, being 2.82% myopic astigmatism and 39.35% hyperopic astigmatism. The 94.1% of hyperopic astigmatism was with-the-rule astigmatism and 71.83% of myopic astigmatism was with-the-rule astigmatism. Refractive state between boys and girls was different. The mean SE of boys was +1.97+1.57 D, while that of girls was +1.79+1.46 D, and the difference was significant. CONCLUSION: Before one year old, the change of refractive status is associated with checking age and sex. At the age of one to two months, the degree of hyperopia reaches the top. Boys have more hyperopic degree than girls, and with- the-rule astigmatism is predominant. Excluding premature infants with advanced retinopathy of prematurity, premature and full-term children have same refraction status.展开更多
基金This work was supported in part by the 863 Hi tech Plan of China(No Z19-01-04 02).
文摘To determine the sensitivity and specificity of using a computer photoscreener and non cycloplegic retinoscopy in the detection of amblyopiogenic factors in nine to fifty months old infants and children Methods Three hundred children, nine to fifty months old, were screened with the computer photoscreener and non cycloplegic retinoscopy With a blinded standardized clinical assessment as the standard, an overall comparison of the sensitivity of and specificity results obtained with the two techniques was made Photoscreen images on the computer monitor screen were reviewed and analyzed immediately by two independent observers for indicators of amblyopiogenic risk factors Simultaneously, the results were compared to the findings of a full ophthalmologic examination Results The computer photoscreener revealed a sensitivity of 94 6% and specificity of 90 1%, and the non cycloplegic retinocopy revealed a sensitivity of 85 7% and specificity of 81 0% for the detection of amblyopiogenic risk factors, including hyperopia (+2 75 D or more), myopia (-1 50 D or more), astigmatism (1 75 D or more), anisometropia (2 00 D or more), ocular misalignment (5 degrees or more), and media opacity (1 5?mm or more) Conclusions The computer photoscreener offers an opportunity to identify problems that limit vision, and could provide a feasible and sufficiently reliable screening technique in infants and preschool children to be screened successfully for amblyopiogenic risk factors
基金Supported by Shandong Nature Scienc Foundation(No.ZR2015HM026)
文摘AIM: To study the evolution of the refractive status and examine the affected factors in infants during the first year of life in a large sample size in China. METHODS: A total of 1258 babies (2516 eyes) aged 32wk gestational age to ty participated in the study, including 766 premature and 492 full-term infants. First, each baby received an orthoptic examination, slit-lamp checking and fundus imaging. Patients with diseases which might affect refractive status were excluded from the cohort. The cycloplegia retinoscopy was performed. Their neonatal histories were reviewed. Each measurement contained the refractive status and calculation of the spherical equivalent (SE). RESULTS: Refractive state showed an average hyperopia of +0.94_+1.63 D at early ages, followed by a trend toward more hyperopia. The refractive state reached the top (+2.431.46 D) at the age of one to two months. Then gliding till one year old when the refractive state reached +0.59:1.41 D. The prevalence of astigmatism was 42.17% in the study, being 2.82% myopic astigmatism and 39.35% hyperopic astigmatism. The 94.1% of hyperopic astigmatism was with-the-rule astigmatism and 71.83% of myopic astigmatism was with-the-rule astigmatism. Refractive state between boys and girls was different. The mean SE of boys was +1.97+1.57 D, while that of girls was +1.79+1.46 D, and the difference was significant. CONCLUSION: Before one year old, the change of refractive status is associated with checking age and sex. At the age of one to two months, the degree of hyperopia reaches the top. Boys have more hyperopic degree than girls, and with- the-rule astigmatism is predominant. Excluding premature infants with advanced retinopathy of prematurity, premature and full-term children have same refraction status.