Objective: To evaluate the clinical efficacy and safety of patient-controlled intravenous analgesia (PCIA) with fentanyl for cystospasm after transurethral resection of the prostate. Methods: Sixty benign prostatic hy...Objective: To evaluate the clinical efficacy and safety of patient-controlled intravenous analgesia (PCIA) with fentanyl for cystospasm after transurethral resection of the prostate. Methods: Sixty benign prostatic hyperplasia (BPH) patients scheduled for transurethral resection of the prostate (TURP) under general anesthesia with laryngeal mask airway (LMA) were randomly divided into groups F and S. Group F (n=30) received PCIA device with fentanyl 10 μg/kg+8 mg ondansetron, and Group S (n=30) received placebo (PCIA device with 8 mg ondansetron). The visual analog scale (VAS) scores for pain were evaluated at 0, 2, 4, 8, 16, 24, and 48 h by the same staff. And recorded were incidence of cystospasm, side effects, application of hemostatic, duration of drawing Foley catheter and continuous bladder irrigation, time of exhaust after operation, time of post-operative stay and cost of hospitalization. Results: The incidence of cystospasm in Group F was significantly lower than that in Group S in the 48 h after operation (P<0.05), the VAS scores for pain in Group F was significantly lower than that in Group S within the 48 h after operation (P<0.01). The time of exhaust after operation in Group F was significantly later than in Group S (P<0.05). No significant difference was observed in applications of hemostatic, duration of drawing Foley catheter, duration of continuous bladder irrigation, time of post-operative stay and cost of hospitalization between the 2 groups. Conclusion: PCIA with fentanyl (10 μg/kg) relieves pain with little side effect and reduces cystospasm satisfactorily.展开更多
目的探讨良性前列腺增生患者接受经尿道前列腺电切手术术中出血量与术后发生膀胱痉挛及精神障碍的相关性。方法回顾分析我科2009年至2013年5年共322例良性前列腺增生接受经尿道前列腺电切术的患者资料。筛选出的病例根据出血量(H)分组为...目的探讨良性前列腺增生患者接受经尿道前列腺电切手术术中出血量与术后发生膀胱痉挛及精神障碍的相关性。方法回顾分析我科2009年至2013年5年共322例良性前列腺增生接受经尿道前列腺电切术的患者资料。筛选出的病例根据出血量(H)分组为H<400 m L、400 m L≤H<600 m L、600 m L≤H<800 m L、H≥800 m L 4组。根据无明显症状、症状轻微无需处理、症状较重需要处理的标准计算术后发生膀胱痉挛及精神障碍严重程度及病例数。采用统计学方法比较各组之间的差异。结果膀胱痉挛及精神障碍发生率及严重程度随术中出血量的增加而增加。结论良性前列腺增生患者接受经尿道前列腺电切术后膀胱痉挛及精神障碍的发生率随着术中出血量的增加而增加。展开更多
文摘Objective: To evaluate the clinical efficacy and safety of patient-controlled intravenous analgesia (PCIA) with fentanyl for cystospasm after transurethral resection of the prostate. Methods: Sixty benign prostatic hyperplasia (BPH) patients scheduled for transurethral resection of the prostate (TURP) under general anesthesia with laryngeal mask airway (LMA) were randomly divided into groups F and S. Group F (n=30) received PCIA device with fentanyl 10 μg/kg+8 mg ondansetron, and Group S (n=30) received placebo (PCIA device with 8 mg ondansetron). The visual analog scale (VAS) scores for pain were evaluated at 0, 2, 4, 8, 16, 24, and 48 h by the same staff. And recorded were incidence of cystospasm, side effects, application of hemostatic, duration of drawing Foley catheter and continuous bladder irrigation, time of exhaust after operation, time of post-operative stay and cost of hospitalization. Results: The incidence of cystospasm in Group F was significantly lower than that in Group S in the 48 h after operation (P<0.05), the VAS scores for pain in Group F was significantly lower than that in Group S within the 48 h after operation (P<0.01). The time of exhaust after operation in Group F was significantly later than in Group S (P<0.05). No significant difference was observed in applications of hemostatic, duration of drawing Foley catheter, duration of continuous bladder irrigation, time of post-operative stay and cost of hospitalization between the 2 groups. Conclusion: PCIA with fentanyl (10 μg/kg) relieves pain with little side effect and reduces cystospasm satisfactorily.
文摘目的探讨良性前列腺增生患者接受经尿道前列腺电切手术术中出血量与术后发生膀胱痉挛及精神障碍的相关性。方法回顾分析我科2009年至2013年5年共322例良性前列腺增生接受经尿道前列腺电切术的患者资料。筛选出的病例根据出血量(H)分组为H<400 m L、400 m L≤H<600 m L、600 m L≤H<800 m L、H≥800 m L 4组。根据无明显症状、症状轻微无需处理、症状较重需要处理的标准计算术后发生膀胱痉挛及精神障碍严重程度及病例数。采用统计学方法比较各组之间的差异。结果膀胱痉挛及精神障碍发生率及严重程度随术中出血量的增加而增加。结论良性前列腺增生患者接受经尿道前列腺电切术后膀胱痉挛及精神障碍的发生率随着术中出血量的增加而增加。
