Objective: The present study aimed to analyze the association rules of Fufang Kushen injection in combination with other traditional Chinese medicine ( TCM) or modern medications in treating cervical cancer (CC) based...Objective: The present study aimed to analyze the association rules of Fufang Kushen injection in combination with other traditional Chinese medicine ( TCM) or modern medications in treating cervical cancer (CC) based on the electrical medical records extracted from real-world hospital information system. Methods: The clinicians’ prescriptions regarding to the combination of with TCM or modern medications were from hospital information system electronic medical data integration warehouse established by the Institute of Basic Medical Research of Chinese Medicine, China Academy of Chinese Medical Sciences, which integrated the hospital information system data of 22 hospitals. The association rules of the drug characteristics were analyzed through Apriori algorithm. Results: A total of 839 patients with CC were included. We found that is often combined with prescriptions which could clear heat, remove toxicity, supplement Qi. also combined with chemotherapeutic drugs, immunomodulatory drugs, 5-HT receptor blockers, and glucocorticoids. The combination presents a specific law. Conclusion: Fufang Kushen injection combined with hepatoprotective drugs, immunomodulators and glucocorticoids is often used to treat cervical cancer.展开更多
Evidence theory is widely used in the field of target recognition. The invalidation problem of this theory when dealing with highly conflict evidences is a research hotspot. Several alternatives of the combination rul...Evidence theory is widely used in the field of target recognition. The invalidation problem of this theory when dealing with highly conflict evidences is a research hotspot. Several alternatives of the combination rule are analyzed and compared. A new combination approach is proposed. Calculate the reliabilities of evidence sources using existing evidences. Construct reliabilities judge matrixes and get the weights of each evidence source. Weight average all inputted evidences. Combine processed evidences with D-S combination rule repeatedly to identify a target. The application in multi-sensor target reeognition as well as the comparison with typical alternatives all validated that this approach can dispose highly conflict evidences efficiently and get reasonable reeognition results rapidly.展开更多
An accurate estimation of the applied load pattern is an essential component in each pushover procedure. Recently, a number of adaptive pushover methods have been proposed in which the effects of the higher modes as w...An accurate estimation of the applied load pattern is an essential component in each pushover procedure. Recently, a number of adaptive pushover methods have been proposed in which the effects of the higher modes as well as the progressive changes in the dynamic characteristics of structures are taken into account to compute the applied load pattern. The basic shortcoming of these advanced pushover methods is related to employing the quadratic modal combination rule, whereby the sign reversals of the modal load vectors are suppressed. In this study, an improved displacement-based adaptive pushover method is developed in which the applied load pattern is computed using the factor modal combination rule(FMC). In the proposed procedure, multiple load patterns, depending on the number of the modes considered, are determined in order to take into account the sign reversals of different modal load vectors. The accuracy of the proposed method is verifi ed for seven moment resisting frame buildings of 3, 9 and 20 stories with regularity or vertically geometric and mass irregularities subjected to 60 earthquake ground motion records. The results showed that the proposed methodology is capable of reproducing the peak dynamic responses with very good accuracy.展开更多
Aiming at the invalidation of DS theory dealing with the evidence in a high conflict and reducing confidence level of DSm theory processing a low conflict,this paper proposes an interactive-adaptive combination rule. ...Aiming at the invalidation of DS theory dealing with the evidence in a high conflict and reducing confidence level of DSm theory processing a low conflict,this paper proposes an interactive-adaptive combination rule. Adopting the angle similarity based on hyper-power set as the weight of generalized Dempster rule and PCR rule,the new rule adaptively processes various evidence combination issues. In this way,the rule can obtain not only the better fusion of decision making effect in a low conflict,but also the solution to the synthesis in a high conflict. Simulation analysis demonstrates the validity and applicability from this rule of combination.展开更多
文摘Objective: The present study aimed to analyze the association rules of Fufang Kushen injection in combination with other traditional Chinese medicine ( TCM) or modern medications in treating cervical cancer (CC) based on the electrical medical records extracted from real-world hospital information system. Methods: The clinicians’ prescriptions regarding to the combination of with TCM or modern medications were from hospital information system electronic medical data integration warehouse established by the Institute of Basic Medical Research of Chinese Medicine, China Academy of Chinese Medical Sciences, which integrated the hospital information system data of 22 hospitals. The association rules of the drug characteristics were analyzed through Apriori algorithm. Results: A total of 839 patients with CC were included. We found that is often combined with prescriptions which could clear heat, remove toxicity, supplement Qi. also combined with chemotherapeutic drugs, immunomodulatory drugs, 5-HT receptor blockers, and glucocorticoids. The combination presents a specific law. Conclusion: Fufang Kushen injection combined with hepatoprotective drugs, immunomodulators and glucocorticoids is often used to treat cervical cancer.
基金This project was supported by the National "863" High Technology Research and Development Program of China(2001AA602021)
文摘Evidence theory is widely used in the field of target recognition. The invalidation problem of this theory when dealing with highly conflict evidences is a research hotspot. Several alternatives of the combination rule are analyzed and compared. A new combination approach is proposed. Calculate the reliabilities of evidence sources using existing evidences. Construct reliabilities judge matrixes and get the weights of each evidence source. Weight average all inputted evidences. Combine processed evidences with D-S combination rule repeatedly to identify a target. The application in multi-sensor target reeognition as well as the comparison with typical alternatives all validated that this approach can dispose highly conflict evidences efficiently and get reasonable reeognition results rapidly.
文摘An accurate estimation of the applied load pattern is an essential component in each pushover procedure. Recently, a number of adaptive pushover methods have been proposed in which the effects of the higher modes as well as the progressive changes in the dynamic characteristics of structures are taken into account to compute the applied load pattern. The basic shortcoming of these advanced pushover methods is related to employing the quadratic modal combination rule, whereby the sign reversals of the modal load vectors are suppressed. In this study, an improved displacement-based adaptive pushover method is developed in which the applied load pattern is computed using the factor modal combination rule(FMC). In the proposed procedure, multiple load patterns, depending on the number of the modes considered, are determined in order to take into account the sign reversals of different modal load vectors. The accuracy of the proposed method is verifi ed for seven moment resisting frame buildings of 3, 9 and 20 stories with regularity or vertically geometric and mass irregularities subjected to 60 earthquake ground motion records. The results showed that the proposed methodology is capable of reproducing the peak dynamic responses with very good accuracy.
基金supported by Pre-Research Foundation of PLA(LY200838014)supported by the PLA Research Program of Science and Technology (KJ08062)
文摘Aiming at the invalidation of DS theory dealing with the evidence in a high conflict and reducing confidence level of DSm theory processing a low conflict,this paper proposes an interactive-adaptive combination rule. Adopting the angle similarity based on hyper-power set as the weight of generalized Dempster rule and PCR rule,the new rule adaptively processes various evidence combination issues. In this way,the rule can obtain not only the better fusion of decision making effect in a low conflict,but also the solution to the synthesis in a high conflict. Simulation analysis demonstrates the validity and applicability from this rule of combination.
