期刊文献+
共找到15篇文章
< 1 >
每页显示 20 50 100
Pixu syndrome grading and its relationship with d-xylose and BT-PABA absorption in 183 patients
1
作者 柯清林 李雪巧 +3 位作者 刘莹 赵荣莱 危北海 金敬善 《World Journal of Gastroenterology》 SCIE CAS CSCD 1996年第1期13-15,共3页
AIMS To study the grading of pixu(spleen deficiency)syn- drome and the scientific basis of its relationship with absorption of D-Xylose and BT-PABA. METHODS The present study included 115 cases of chronic su- perficia... AIMS To study the grading of pixu(spleen deficiency)syn- drome and the scientific basis of its relationship with absorption of D-Xylose and BT-PABA. METHODS The present study included 115 cases of chronic su- perficial gastritis,15 cases of chronic atrophic gastritis,19 cases of peptic ulcer and 34 cases of chronic colitis.All of them were diagnosed by endoscopy and biopsies.Chronic gastrointestinal diseases could be categorized into six types,namely,spleen and stomach asthenia syndrome(including asthenia and cold),dishar- mony between liver and stomach,damp and heat of spleen and stomach(bowel)syndrome,spleen-stomach-Yin deficiency,blood stasis and spleen-kidney-Yang deficiency.Grading of these syn- dromes were made with concomitant estimation of d-xylose and BT-PABA tests. RESULTS Patients with chronic gastrointestinal diseases showed diminished urinary level of d-xylosc and that of BT- PABA,as compared with normal,(P<0.05),except those with damp and heat of spleen-bowel syndrome.The excretory rate of d-xylosc was neary normal,while the levels of d-xylose and BT-PABA were lower than those of the normal,(P<0.05-0. 01).In regard to the grading of spleen deficiency and the dishar- mony between liver and stomach syndromes,the excretory rate of D-Xylose decreased gradually(P<0.01 )as the severity of symp- toms increased;in disharmony between liver and stomach syndrome,the excretory rate of BT-PABA also decreased(P<0. 01)as symptoms worsened.These provided scientific proofs for appraisal of the pathophysiology of these syndromes. CONCLUSIONS Changes of d-xylose can reflect the specifici- ty of pixu syndrome whereas changes of BT-PABA reflect the specificity of disharmony between liver and stomach syndrome. 展开更多
关键词 spleen asthenia gastrointestinal diseases d-xylose BT-PABA
下载PDF
Biomass-based N doped carbon as metal-free catalyst for selective oxidation of D-xylose into D-xylonic acid 被引量:1
2
作者 Zengyong Li Yiming Huang +5 位作者 Xiao Chi Di Li Linxin Zhong Xuehui Li Chuanfu Liu Xinwen Peng 《Green Energy & Environment》 SCIE EI CSCD 2022年第6期1310-1317,共8页
Rational design and facile preparation of low-cost and efficient catalysts for the selective converting of biomass-derived monosaccharides into high value-added chemicals is highly demanded,yet challenging.Herein,we f... Rational design and facile preparation of low-cost and efficient catalysts for the selective converting of biomass-derived monosaccharides into high value-added chemicals is highly demanded,yet challenging.Herein,we first demonstrate a N doped defect-rich carbon(NC-800-5)as metal-free catalyst for the selective oxidation of D-xylose into D-xylonic acid in alkaline aqueous solution at 100℃ for 30 min,with 57.4%yield.The doped graphitic N is found to be the active site and hydroxyl ion participating in the oxidation of D-xylose.Hydroxyl ion and D-xylose first adsorb on NC-800-5 surface,and the aldehyde group of D-xylose is catalyzed to form germinal diols ion.Then,C–H bond break to yield carboxylic group.Furthermore,NC-800-5 catalyst shows high stability in recycled test. 展开更多
关键词 Biomass carbon Metal-free catalysts d-xylose Sugar acid Selective oxidation
下载PDF
Experimental measurement and thermodynamic modeling of binary and ternary solid–liquid phase equilibrium for the systems formed by L-arabinose,D-xylose and water 被引量:1
3
作者 Lei Guo Lianying Wu +2 位作者 Weitao Zhang Chen Liang Yangdong Hu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2017年第10期1467-1472,共6页
Solid–liquid phase equilibrium data for binary(L-arabinose–water) and(D-xylose–water) systems at temperatures from(269.85–298.05) K and ternary(L-arabinose–D-xylose–water) system at temperatures of 273.85 K,278.... Solid–liquid phase equilibrium data for binary(L-arabinose–water) and(D-xylose–water) systems at temperatures from(269.85–298.05) K and ternary(L-arabinose–D-xylose–water) system at temperatures of 273.85 K,278.85 K and 284.45 K were measured at atmospheric pressure.The ternary phase diagrams of the systems were constructed on the base of the measured solubility.Two pure solid phases were formed at given temperatures,including pure L-arabinose and pure D-xylose,which were con firmed and determined by the method of Schreinemakers' wet residue.At the same temperature,the crystallization region of L-arabinose was larger than D-xylose's.The acquired solubility data were then correlated using the NRTL model,Wilson model and Xu model.The calculated solubility with the three models agreed well with the experimental values. 展开更多
关键词 d-xylose L-Arabinose Solid–liquid equilibrium Solubility Thermodynamics Model
下载PDF
Synthesis of New Thiazine and Thiosemicarbazone Derivatives from D-Xylose
4
作者 Xiao Ming JI He Ping SUN Hai Wei XU Hong Min LIU 《Chinese Chemical Letters》 SCIE CAS CSCD 2006年第12期1563-1565,共3页
1,2-O-Isopropylidene-5-O-p-toluenesulfonyl-α-D-erythro-pentofuranos-3-ulose 1 was treated with thiourea and aminothiourea to give a D-ribose derivative 2 bearing a 2-amino 1,3-thiazine ring and a thiosemicarbazone de... 1,2-O-Isopropylidene-5-O-p-toluenesulfonyl-α-D-erythro-pentofuranos-3-ulose 1 was treated with thiourea and aminothiourea to give a D-ribose derivative 2 bearing a 2-amino 1,3-thiazine ring and a thiosemicarbazone derivative 5, respectively. 2 was acylated with Ac20 and propandioic acid to afford two acylation derivatives 3 and 4, respectively. Reduction of 5 with NaBH4 in methanol produced a hydrothiosemicarbazone derivative 6. The absolute configuration of 2 was confirmed by X-ray crystallographic analysis. The structures of all products were elucidated by IR, NMR and HRMS spectra. 展开更多
关键词 THIOUREA aminothiourea THIAZINE d-xylose synthesis.
下载PDF
Determination and Correlation of Solubility for D-Xylose in Volatile Fatty Acid Solvents
5
作者 李涛 陈飞雄 +1 位作者 江振西 任保增 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2014年第4期429-434,共6页
The solubility of D-xylose in formic acid and binary solvents of formic acid with formic acid and acetic acid, propionic acid, n-butyric acid or isobutyric acid was measured in the temperature range from 300.35 to 325... The solubility of D-xylose in formic acid and binary solvents of formic acid with formic acid and acetic acid, propionic acid, n-butyric acid or isobutyric acid was measured in the temperature range from 300.35 to 325.05 K using the synthetic method by a laser monitoring technique at atmospheric pressure. The solid-liquid equilibrium data will provide essential support for industrial design and further theoretical study. The experimental data show that the solubility of D-xylose in formic acid and in the mixtures of formic acid + acetic acid(1︰1), formic acid + propionic acid(1︰1), formic acid + n-butyric acid(1︰1), and formic acid + isobutyric acid(1︰1) increases with temperature. The Apelblat equation, the λh model, and the ideal solution equation correlate the solubility data well. 展开更多
关键词 solid-liquid equilibrium SOLUBILITY d-xylose
下载PDF
龙牙楤木总皂苷对缺氧/再给氧心肌细胞损伤的保护作用 被引量:20
6
作者 孙桂波 徐惠波 +3 位作者 温富春 张伟 丁涛 孙晓波 《中国药理学通报》 CAS CSCD 北大核心 2006年第9期1092-1095,共4页
目的探讨龙牙楤木总皂苷(As)对培养心肌细胞缺氧/再给氧损伤的保护作用及其机制。方法取体外培养的乳大鼠心肌细胞建立缺氧/再给氧心肌细胞损伤模型,实验分为5组空白对照组;模型组(A/R组),缺氧6h再给氧3h;3个As给药组,缺氧6h再给氧3h,... 目的探讨龙牙楤木总皂苷(As)对培养心肌细胞缺氧/再给氧损伤的保护作用及其机制。方法取体外培养的乳大鼠心肌细胞建立缺氧/再给氧心肌细胞损伤模型,实验分为5组空白对照组;模型组(A/R组),缺氧6h再给氧3h;3个As给药组,缺氧6h再给氧3h,并于缺氧及再给氧开始时分别加入终浓度为1.25、2.5、5.0mg.L-1的As,观察As对细胞上清液中缺氧及再给氧后LDH、CK漏出量、MDA含量、SOD活性的影响。用MTT法检测As对缺氧再给氧损伤心肌细胞线粒体的保护作用。结果As可抑制缺氧及再给氧后LDH、CK漏出量,降低MDA含量,提高SOD活性,升高OD570吸光度值。结论As对培养心肌细胞的缺氧再给氧损伤具有保护作用,提示其作用机制与增强细胞抗氧化作用,减少自由基及脂质过氧化物导致的细胞膜损伤有关。 展开更多
关键词 龙牙楤木总皂苷 心肌细胞培养 超氧化物歧化酶 乳酸脱氢酶 肌酸激酶
下载PDF
去葡萄糖竹节参皂苷Ⅳa对缺氧复氧心肌细胞损伤的保护作用 被引量:10
7
作者 孙桂波 徐惠波 +3 位作者 温富春 张伟 丁涛 孙晓波 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2005年第6期424-427,共4页
目的研究去葡萄糖竹节参皂苷Ⅳa(DCⅣa)是否为龙牙木匆心木总皂苷抗心肌缺血的有效成分之一。方法取体外培养的新生大鼠心肌细胞建立缺氧6 h复氧3 h心肌细胞损伤模型,并于缺氧及复氧开始时分别加入终浓度为2.5,1.0和0.1 mg.L-1的DCⅣa... 目的研究去葡萄糖竹节参皂苷Ⅳa(DCⅣa)是否为龙牙木匆心木总皂苷抗心肌缺血的有效成分之一。方法取体外培养的新生大鼠心肌细胞建立缺氧6 h复氧3 h心肌细胞损伤模型,并于缺氧及复氧开始时分别加入终浓度为2.5,1.0和0.1 mg.L-1的DCⅣa。检测细胞培养上清液中乳酸脱氢酶(LDH)和肌酸激酶(CK)漏出量,丙二醛(MDA)含量及超氧化物歧化酶(SOD)活性。MTT法检测心肌细胞存活率。结果DCⅣa(2.5,1.0 mg.L-1)显著减少缺氧及复氧后LDH和CK漏出量,降低MDA含量,提高SOD活性,提高心肌细胞存活率。结论DCⅣa为龙牙木匆心木总皂苷抗心肌缺血的有效成分之一,可减轻缺氧复氧对心肌细胞的损伤,对心肌细胞具有直接的保护作用。 展开更多
关键词 皂苷 龙牙楤木 去葡萄糖竹节参皂苷Ⅳa 心肌 细胞 培养的 细胞低氧 超氧化物歧化酶 乳酸脱氢酶 肌酸激酶
下载PDF
A controllable soft-templating approach to synthesize mesoporous carbon microspheres derived from d-xylose via hydrothermal method 被引量:4
8
作者 Jian Su Changqing Fang +4 位作者 Mannan Yang Youliang Cheng Zhen Wang Zhigang Huang Caiyin You 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2020年第3期183-188,共6页
Highly dispersed carbon microspheres(CMSs)derived from D-xylose were successfully synthesized under hydrothermal conditions and followed by further carbonization,in which F127 was used as a soft template.As-synthesize... Highly dispersed carbon microspheres(CMSs)derived from D-xylose were successfully synthesized under hydrothermal conditions and followed by further carbonization,in which F127 was used as a soft template.As-synthesized products were characterized by scanning electron microscopy(SEM),transmission electron microscopy(TEM),flourier transform infrared spectroscopy(FT-IR),thermal gravimetric(TG)and X-ray diffraction(XRD).The results showed that the morphology and structure of the CMSs prominently depended on the stirring speed during hydrothermal reaction.The resultant CMSs principally had non-porous structure without stirring and had a very smooth surface.When the stirring speed increased to 200 rpm,the synthesized mesoporous carbon microspheres at 220?C for 24 h(CMSs-5)had a uniform size distribution of 1–1.4μm and a specific surface area of 452 m^2/g.Nevertheless,with further increasing to 400 rpm,as-fabricated carbon products were mostly amorphous with a low degree of sphericity.Results demonstrated that the diameter of the products decreased with the increase of stirring speed.Furthermore,the sphericity product yield of CMSs reduced with the increase of stirring speed.XRD result showed that all the obtained samples contained partial graphite phase.In addition,a formation mechanism was proposed that involved polymerization product as the precursors for microsphere formation.The controllable and green strategy may provide a great convenience to study properties and applications of carbon microspheres. 展开更多
关键词 d-xylose Mesoporous carbon MICROSPHERE SOFT template Hydrothermal method STIRRING
原文传递
The green hydrolysis technology of hemicellulose in corncob by the repeated use of hydrolysate 被引量:2
9
作者 Lei Guo Yangdong Hu +2 位作者 Lianying Wu Chen Liang Weitao Zhang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2018年第1期191-195,共5页
To achieve green hydrolysis technology of hemicellulose through repeated using hydrolysate, the hydrolysis of hemicellulose in corncob was studied. The influence of repeated use of corncob hydrolysate on concentration... To achieve green hydrolysis technology of hemicellulose through repeated using hydrolysate, the hydrolysis of hemicellulose in corncob was studied. The influence of repeated use of corncob hydrolysate on concentrations of D-xylose and L-arabinose was investigated. The loss rates of D-xylose in the prepared D-xylose solutions both with and without corncob, and repeated using corncob hydrolysate under identical acidity condition were discussed. The result shows that D-XyIOSe concentration and L-arabinose concentration are all gradually increas- ing with the growing time of repeated use of corncob hydrolysate. After the fifth repetition, the concentrations of D-xylose and L-arabinose are 196.7 g. L-1 and 22.0 g.L-1, respectively. Substance inhibiting the degradation of D-xylose is generated during repeated use of corncob hydrolysate, and the production is further proved by the change of D-xylose concentration and the loss rate of D-xylose over heating time. 展开更多
关键词 d-xylose Repeatedly-using hydrolysate Acidolysis Water-saving Acid-saving
下载PDF
atRA对原代培养的猪甲状腺细胞生存率及细胞损伤的实验研究
10
作者 马宝丰 刘用璋 +2 位作者 朱晓敏 孙浩 李雪 《锦州医学院学报》 2005年第2期9-11,共3页
目的 研究全反式维甲酸(atRA)对猪甲状腺细胞生长调节及细胞损伤的作用。方法 采用正常猪甲状腺组织,以细胞单层培养、噻唑蓝(MTT)法及乳酸脱氢酶(LDH)的活性测定,检测不同浓度的atRA (10 -8~10 - 5mol/L)对甲状腺细胞存活率及损伤... 目的 研究全反式维甲酸(atRA)对猪甲状腺细胞生长调节及细胞损伤的作用。方法 采用正常猪甲状腺组织,以细胞单层培养、噻唑蓝(MTT)法及乳酸脱氢酶(LDH)的活性测定,检测不同浓度的atRA (10 -8~10 - 5mol/L)对甲状腺细胞存活率及损伤的影响。结果 atRA呈剂量依赖性抑制甲状腺细胞的生长,亦呈剂量依赖性损伤细胞。结论 一定浓度的atRA对甲状腺细胞具有一定的细胞毒作用。 展开更多
关键词 atRA 乳酸脱氢酶 维甲酸受体
下载PDF
SIRT5通过调控G6PD促进结肠癌细胞的糖代谢及增殖 被引量:1
11
作者 刘迪 张秀梅 《中国肿瘤临床》 CAS CSCD 北大核心 2021年第17期876-881,共6页
目的:探讨SIRT5对结肠癌细胞糖代谢和增殖的作用及其可能的作用机制,以及SIRT5、G6PD在结肠癌组织中的表达情况。方法:Western blot法检测SIRT5蛋白在结肠癌细胞系HCT116、HT29中的表达水平,构建SIRT5基因过表达及siRNA沉默载体分别转染... 目的:探讨SIRT5对结肠癌细胞糖代谢和增殖的作用及其可能的作用机制,以及SIRT5、G6PD在结肠癌组织中的表达情况。方法:Western blot法检测SIRT5蛋白在结肠癌细胞系HCT116、HT29中的表达水平,构建SIRT5基因过表达及siRNA沉默载体分别转染到SIRT5低表达与SIRT5高表达结肠癌细胞系,葡萄糖氧化酶法、比色法分别检测培养液中葡萄糖、乳酸的含量;CCK-8实验检测细胞活力;克隆形成实验检测细胞增殖能力。RT-PCR与Western blot法分别检测SIRT5对G6PD mRNA及蛋白表达的调控;免疫组织化学法检测结肠癌组织中SIRT5、G6PD的表达情况。结果:沉默SIRT5后,细胞培养液中葡萄糖的浓度明显升高、乳酸的浓度明显降低,细胞的活性和增殖能力明显减弱;过表达SIRT5后,细胞培养液中葡萄糖的浓度明显降低、乳酸的浓度明显升高,细胞的活性和增殖能力明显增强。SIRT5正向调控G6PD的基因表达与单独转染si-SIRT5相比,共转染si-SIRT5与G6PD质粒恢复了结肠癌细胞的糖代谢及增殖能力;SIRT5、G6PD在结肠癌组织中的表达明显高于癌旁组织。结论:SIRT5、G6PD在结肠癌组织中高表达,SIRT5通过调控G6PD促进结肠癌细胞糖代谢和增殖。 展开更多
关键词 结肠癌 SIRT5 G6PD 有氧糖酵解
下载PDF
Effect of external electric field upon charge distribution, energy and dipole moment of selected monosaccharide molecules
12
作者 Jozef Mazurkiewicz Piotr Tomasik 《Natural Science》 2012年第5期276-285,共10页
External electric field of 0.001, 0.01 and 0.05 a.u. changes distribution of the electron density in α- and β-D-glucose, α- and β-D-galactose, α- and β-fructopyranoses and α- and β-fructofuranoses, α- and β-... External electric field of 0.001, 0.01 and 0.05 a.u. changes distribution of the electron density in α- and β-D-glucose, α- and β-D-galactose, α- and β-fructopyranoses and α- and β-fructofuranoses, α- and β-D-ribofuranoses and α and β-D-xylo- furanoses. Hyper-Chem 8.0 software was used together with the AM1 method for optimization of the conformation of the molecules of monosaccharides under study. Then polarizability, charge distribution, potential and dipole moment for molecules placed in the external electric field of 0.000, 0.001, 0.01 and 0.05 a.u. were calculated involving DFT 3-21G method. Application of the external field induced polarizability of electrons, atoms and dipoles, the latter resulting in eventual reorientation of the molecules along the applied field of the molecules and the electron density redistribution at particular atoms. Increase in the field strength generated mostly irregular changes of the electron densities at particular atoms of the molecules as well as polarizabilities. Energy of these molecules and their dipole moments also varied with the strength of the field applied. Results of computations imply that saccharides present in the living organisms may participate in the response of the living organisms to the external electric field affecting metabolism of the molecules in the body fluids by fitting molecules to the enzymes. Structural changes of saccharide components of the membranes can influence the membrane permeability. 展开更多
关键词 D-FRUCTOSE Dipole Moments D-GALACTOSE D-GLUCOSE Polarizabilty D-RIBOSE d-xylose
下载PDF
The mechanism of environmental D-xylose perception by the bacterial membrane two-component complex XylFII-LytS
13
《Science Foundation in China》 CAS 2017年第4期23-,共1页
D-xylose,the main building block of plant biomass,is a pentose sugar that can be used by bacteria as a carbon source for bio-based fuel and chemical production through fermentation.In bacteria,the first step for D-xyl... D-xylose,the main building block of plant biomass,is a pentose sugar that can be used by bacteria as a carbon source for bio-based fuel and chemical production through fermentation.In bacteria,the first step for D-xylose metabolism is signal perception at the membrane.Scientists previously identified a threecomponent system in Firmicutes bacteria comprising a membrane-associated sensor protein(XylFII)。 展开更多
关键词 The mechanism of environmental d-xylose perception by the bacterial membrane two-component complex XylFII-LytS
原文传递
代谢工程改造大肠杆菌合成D-1,2,4-丁三醇 被引量:6
14
作者 孙文龙 陆信曜 +3 位作者 宗红 方慧英 诸葛斌 宋健 《微生物学通报》 CAS CSCD 北大核心 2014年第10期1948-1954,共7页
【目的】D-1,2,4-丁三醇是一种四碳的多元醇,在军事和医药领域具有广泛的应用。为实现生物法一步转化生产D-1,2,4-丁三醇,对Escherichia coli W3100的木糖代谢途径进行改造。【方法】将来源于柄杆菌的D-木糖脱氢酶基因xylB和恶臭假单胞... 【目的】D-1,2,4-丁三醇是一种四碳的多元醇,在军事和医药领域具有广泛的应用。为实现生物法一步转化生产D-1,2,4-丁三醇,对Escherichia coli W3100的木糖代谢途径进行改造。【方法】将来源于柄杆菌的D-木糖脱氢酶基因xylB和恶臭假单胞菌的苯甲酰甲酸脱羧酶基因mdlC克隆至E.coli W3100,得到重组菌E.coli(pEtac-mdlC-tac-xylB)。在此基础上对重组菌代谢木糖合成D-1,2,4-丁三醇的能力进行考察。【结果】在30°C下,以30 g/L D-木糖为底物,重组菌E.coli(pEtac-mdlC-tac-xylB)的D-1,2,4-丁三醇产量达到了0.9 g/L,摩尔转化率为4%。【结论】实现了D-1,2,4-丁三醇的一步法发酵生产,为国内开展相关研究奠定了坚实的基础。 展开更多
关键词 D-木糖 D-木糖脱氢酶 苯甲酰甲酸脱羧酶 D-1 2 4-丁三醇 重组大肠杆菌
原文传递
G6PD活性与地中海贫血的关系 被引量:5
15
作者 黄霜 朱文彪 陈秋霞 《中华全科医学》 2012年第7期1140-1141,共2页
目的地中海贫血(地贫)是南方最常见的遗传病,检出亲代的携带者是预防重型患儿出生的唯一方法。本文探讨G6PD(葡萄糖-6-磷酸脱氢酶)活性与地中海贫血的关系,指导临床的地中海贫血筛查。方法收集2011年1月1日-2011年12月31日医院产科门诊... 目的地中海贫血(地贫)是南方最常见的遗传病,检出亲代的携带者是预防重型患儿出生的唯一方法。本文探讨G6PD(葡萄糖-6-磷酸脱氢酶)活性与地中海贫血的关系,指导临床的地中海贫血筛查。方法收集2011年1月1日-2011年12月31日医院产科门诊、婚前检查门诊的就诊者检验结果。以血常规MCV(平均红细胞体积)<82 fl和血红蛋白电泳HbA2>3.5%为标准筛选652例β地中海贫血患者,以100例健康者为正常对照;速率法检测G6PD活性。将β地贫组的G6PD活性和MCV与对照组比较,采用SPSS 10.0 for Windows进行统计分析,两组均数以t检验进行比较。结果β地贫组的G6PD活性显著性高于对照组(P<0.001),而β地贫组MCV显著性低于对照组(P<0.01)。结论 G6PD活性的升高可以提示地中海贫血。基层医院或门诊部可通过检测G6PD进行地中海贫血的筛查。 展开更多
关键词 G6PD 地中海贫血 MCV
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部