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Comparative analysis of empirical and deep learning models for ionospheric sporadic E layer prediction
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作者 BingKun Yu PengHao Tian +6 位作者 XiangHui Xue Christopher JScott HaiLun Ye JianFei Wu Wen Yi TingDi Chen XianKang Dou 《Earth and Planetary Physics》 EI CAS 2025年第1期10-19,共10页
Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 km.Because they can significantly influence radio communications and navigation systems,... Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 km.Because they can significantly influence radio communications and navigation systems,accurate forecasting of Es layers is crucial for ensuring the precision and dependability of navigation satellite systems.In this study,we present Es predictions made by an empirical model and by a deep learning model,and analyze their differences comprehensively by comparing the model predictions to satellite RO measurements and ground-based ionosonde observations.The deep learning model exhibited significantly better performance,as indicated by its high coefficient of correlation(r=0.87)with RO observations and predictions,than did the empirical model(r=0.53).This study highlights the importance of integrating artificial intelligence technology into ionosphere modelling generally,and into predicting Es layer occurrences and characteristics,in particular. 展开更多
关键词 ionospheric sporadic E layer radio occultation ionosondes numerical model deep learning model artificial intelligence
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Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis
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作者 Li Xu Huiming Xu Changyong Tang 《Neural Regeneration Research》 SCIE CAS 2025年第2期354-365,共12页
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism rem... Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials. 展开更多
关键词 AQUAPORIN-4 experimental model neuromyelitis optica spectrum disorder PATHOGENESIS
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Landslide Susceptibility Mapping Using RBFN-Based Ensemble Machine Learning Models
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作者 Duc-Dam Nguyen Nguyen Viet Tiep +5 位作者 Quynh-Anh Thi Bui Hiep Van Le Indra Prakash Romulus Costache Manish Pandey Binh Thai Pham 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期467-500,共34页
This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble lear... This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and AB-RBFN.Additionally,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and validation.The models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to roads.These factors were instrumental in predicting the output variable,which was the probability of landslide occurrence.Statistical analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other models.The AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of 0.926.These results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making. 展开更多
关键词 Landslide susceptibility map spatial analysis ensemble modelling information values(IV)
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Exploiting fly models to investigate rare human neurological disorders
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作者 Tomomi Tanaka Hyung-Lok Chung 《Neural Regeneration Research》 SCIE CAS 2025年第1期21-28,共8页
Rare neurological diseases,while individually are rare,collectively impact millions globally,leading to diverse and often severe neurological symptoms.Often attributed to genetic mutations that disrupt protein functio... Rare neurological diseases,while individually are rare,collectively impact millions globally,leading to diverse and often severe neurological symptoms.Often attributed to genetic mutations that disrupt protein function or structure,understanding their genetic basis is crucial for accurate diagnosis and targeted therapies.To investigate the underlying pathogenesis of these conditions,researchers often use non-mammalian model organisms,such as Drosophila(fruit flies),which is valued for their genetic manipulability,cost-efficiency,and preservation of genes and biological functions across evolutionary time.Genetic tools available in Drosophila,including CRISPR-Cas9,offer a means to manipulate gene expression,allowing for a deep exploration of the genetic underpinnings of rare neurological diseases.Drosophila boasts a versatile genetic toolkit,rapid generation turnover,and ease of large-scale experimentation,making it an invaluable resource for identifying potential drug candidates.Researchers can expose flies carrying disease-associated mutations to various compounds,rapidly pinpointing promising therapeutic agents for further investigation in mammalian models and,ultimately,clinical trials.In this comprehensive review,we explore rare neurological diseases where fly research has significantly contributed to our understanding of their genetic basis,pathophysiology,and potential therapeutic implications.We discuss rare diseases associated with both neuron-expressed and glial-expressed genes.Specific cases include mutations in CDK19 resulting in epilepsy and developmental delay,mutations in TIAM1 leading to a neurodevelopmental disorder with seizures and language delay,and mutations in IRF2BPL causing seizures,a neurodevelopmental disorder with regression,loss of speech,and abnormal movements.And we explore mutations in EMC1 related to cerebellar atrophy,visual impairment,psychomotor retardation,and gain-of-function mutations in ACOX1 causing Mitchell syndrome.Loss-of-function mutations in ACOX1 result in ACOX1 deficiency,characterized by very-long-chain fatty acid accumulation and glial degeneration.Notably,this review highlights how modeling these diseases in Drosophila has provided valuable insights into their pathophysiology,offering a platform for the rapid identification of potential therapeutic interventions.Rare neurological diseases involve a wide range of expression systems,and sometimes common phenotypes can be found among different genes that cause abnormalities in neurons or glia.Furthermore,mutations within the same gene may result in varying functional outcomes,such as complete loss of function,partial loss of function,or gain-of-function mutations.The phenotypes observed in patients can differ significantly,underscoring the complexity of these conditions.In conclusion,Drosophila represents an indispensable and cost-effective tool for investigating rare neurological diseases.By facilitating the modeling of these conditions,Drosophila contributes to a deeper understanding of their genetic basis,pathophysiology,and potential therapies.This approach accelerates the discovery of promising drug candidates,ultimately benefiting patients affected by these complex and understudied diseases. 展开更多
关键词 ACOX1 Drosophila melanogaster GLIA lipid metabolism model organisms NEUROINFLAMMATION neurologic disorders NEURON rare disease VLCFA
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Rat models of frozen shoulder:Classification and evaluation
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作者 Hezirui Gu Wenqing Xie +2 位作者 Hengzhen Li Shuguang Liu Yusheng Li 《Animal Models and Experimental Medicine》 2025年第1期92-101,共10页
Frozen shoulder(FS),also known as adhesive capsulitis,is a condition that causes contraction and stiffness of the shoulder joint capsule.The main symptoms are per-sistent shoulder pain and a limited range of motion in... Frozen shoulder(FS),also known as adhesive capsulitis,is a condition that causes contraction and stiffness of the shoulder joint capsule.The main symptoms are per-sistent shoulder pain and a limited range of motion in all directions.These symp-toms and poor prognosis affect people's physical health and quality of life.Currently,the specific mechanisms of FS remain unclear,and there is variability in treatment methods and their efficacy.Additionally,the early symptoms of FS are difficult to distinguish from those of other shoulder diseases,complicating early diagnosis and treatment.Therefore,it is necessary to develop and utilize animal models to under-stand the pathogenesis of FS and to explore treatment strategies,providing insights into the prevention and treatment of human FS.This paper reviews the rat models available for FS research,including external immobilization models,surgical internal immobilization models,injection modeling models,and endocrine modeling models.It introduces the basic procedures for these models and compares and analyzes the advantages,disadvantages,and applicability of each modeling method.Finally,our paper summarizes the common methods for evaluating FS rat models. 展开更多
关键词 endocrine modeling INJECTION rat model surgical internal immobilization
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LoRa Sense:Sensing and Optimization of LoRa Link Behavior Using Path-Loss Models in Open-Cast Mines
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作者 Bhanu Pratap Reddy Bhavanam Prashanth Ragam 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期425-466,共42页
The Internet of Things(IoT)has orchestrated various domains in numerous applications,contributing significantly to the growth of the smart world,even in regions with low literacy rates,boosting socio-economic developm... The Internet of Things(IoT)has orchestrated various domains in numerous applications,contributing significantly to the growth of the smart world,even in regions with low literacy rates,boosting socio-economic development.This study provides valuable insights into optimizing wireless communication,paving the way for a more connected and productive future in the mining industry.The IoT revolution is advancing across industries,but harsh geometric environments,including open-pit mines,pose unique challenges for reliable communication.The advent of IoT in the mining industry has significantly improved communication for critical operations through the use of Radio Frequency(RF)protocols such as Bluetooth,Wi-Fi,GSM/GPRS,Narrow Band(NB)-IoT,SigFox,ZigBee,and Long Range Wireless Area Network(LoRaWAN).This study addresses the optimization of network implementations by comparing two leading free-spreading IoT-based RF protocols such as ZigBee and LoRaWAN.Intensive field tests are conducted in various opencast mines to investigate coverage potential and signal attenuation.ZigBee is tested in the Tadicherla open-cast coal mine in India.Similarly,LoRaWAN field tests are conducted at one of the associated cement companies(ACC)in the limestone mine in Bargarh,India,covering both Indoor-toOutdoor(I2O)and Outdoor-to-Outdoor(O2O)environments.A robust framework of path-loss models,referred to as Free space,Egli,Okumura-Hata,Cost231-Hata and Ericsson models,combined with key performance metrics,is employed to evaluate the patterns of signal attenuation.Extensive field testing and careful data analysis revealed that the Egli model is the most consistent path-loss model for the ZigBee protocol in an I2O environment,with a coefficient of determination(R^(2))of 0.907,balanced error metrics such as Normalized Root Mean Square Error(NRMSE)of 0.030,Mean Square Error(MSE)of 4.950,Mean Absolute Percentage Error(MAPE)of 0.249 and Scatter Index(SI)of 2.723.In the O2O scenario,the Ericsson model showed superior performance,with the highest R^(2)value of 0.959,supported by strong correlation metrics:NRMSE of 0.026,MSE of 8.685,MAPE of 0.685,Mean Absolute Deviation(MAD)of 20.839 and SI of 2.194.For the LoRaWAN protocol,the Cost-231 model achieved the highest R^(2)value of 0.921 in the I2O scenario,complemented by the lowest metrics:NRMSE of 0.018,MSE of 1.324,MAPE of 0.217,MAD of 9.218 and SI of 1.238.In the O2O environment,the Okumura-Hata model achieved the highest R^(2)value of 0.978,indicating a strong fit with metrics NRMSE of 0.047,MSE of 27.807,MAPE of 27.494,MAD of 37.287 and SI of 3.927.This advancement in reliable communication networks promises to transform the opencast landscape into networked signal attenuation.These results support decision-making for mining needs and ensure reliable communications even in the face of formidable obstacles. 展开更多
关键词 Internet of things long range wireless area network ZigBee mining environments path-loss models coefficient of determination mean square error
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Predictability Study of Weather and Climate Events Related to Artificial Intelligence Models
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作者 Mu MU Bo QIN Guokun DAI 《Advances in Atmospheric Sciences》 2025年第1期1-8,共8页
Conducting predictability studies is essential for tracing the source of forecast errors,which not only leads to the improvement of observation and forecasting systems,but also enhances the understanding of weather an... Conducting predictability studies is essential for tracing the source of forecast errors,which not only leads to the improvement of observation and forecasting systems,but also enhances the understanding of weather and climate phenomena.In the past few decades,dynamical numerical models have been the primary tools for predictability studies,achieving significant progress.Nowadays,with the advances in artificial intelligence(AI)techniques and accumulations of vast meteorological data,modeling weather and climate events using modern data-driven approaches is becoming trendy,where FourCastNet,Pangu-Weather,and GraphCast are successful pioneers.In this perspective article,we suggest AI models should not be limited to forecasting but be expanded to predictability studies,leveraging AI's advantages of high efficiency and self-contained optimization modules.To this end,we first remark that AI models should possess high simulation capability with fine spatiotemporal resolution for two kinds of predictability studies.AI models with high simulation capabilities comparable to numerical models can be considered to provide solutions to partial differential equations in a data-driven way.Then,we highlight several specific predictability issues with well-determined nonlinear optimization formulizations,which can be well-studied using AI models,holding significant scientific value.In addition,we advocate for the incorporation of AI models into the synergistic cycle of the cognition–observation–model paradigm.Comprehensive predictability studies have the potential to transform“big data”to“big and better data”and shift the focus from“AI for forecasts”to“AI for science”,ultimately advancing the development of the atmospheric and oceanic sciences. 展开更多
关键词 PREDICTABILITY artificial intelligence models simulation and forecasting nonlinear optimization cognition–observation–model paradigm
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Selection of Constitutive Models for As-Cast Low Alloyed Al-xSi-yCu Alloys
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作者 GAO Xiang 《新疆大学学报(自然科学版中英文)》 2025年第1期1-13,23,共14页
To guarantee the computational accuracy of the finite element model,the strain-compensated Arrhenius-type model,modified Fields-Backofen(m-FB)model and modified Zerilli-Armstrong(m-ZA)model were established to predict... To guarantee the computational accuracy of the finite element model,the strain-compensated Arrhenius-type model,modified Fields-Backofen(m-FB)model and modified Zerilli-Armstrong(m-ZA)model were established to predict the hightemperature flow stress of as-cast low alloyed Al-0.5Cu,Al-1Si,and Al-1Si-0.5Cu.To determine the material constants of these three constitutive models,isothermal compression tests of the three aluminum alloys were carried out on a Gleeble-3800 thermal simulator.The prediction results of the constitutive model were compared with the experimental results to evaluate the prediction accuracy of the constitutive models,and to provide a basis for selecting the most suitable constitutive models(parameters)for the three alloys mentioned above.It is found that the strain-compensated Arrhenius model and m-ZA model can be regarded as the most suitable constitutive models for Al-0.5Cu and Al-1Si alloys,respectively,and these two constitutive models also can be applied to Al-1Si-0.5Cu alloy.However,the m-FB model can be applied to Al-0.5Cu,Al-1Si and Al-1Si-0.5Cu alloys only under high temperature and medium strain conditions. 展开更多
关键词 constitutive model flow stress hot deformation aluminum alloy
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Dynamic intelligent prediction approach for landslide displacement based on biological growth models and CNN-LSTM
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作者 WANG Ziqian FANG Xiangwei +3 位作者 ZHANG Wengang WANG Luqi WANG Kai CHEN Chao 《Journal of Mountain Science》 2025年第1期71-88,共18页
Influenced by complex external factors,the displacement-time curve of reservoir landslides demonstrates both short-term and long-term diversity and dynamic complexity.It is difficult for existing methods,including Reg... Influenced by complex external factors,the displacement-time curve of reservoir landslides demonstrates both short-term and long-term diversity and dynamic complexity.It is difficult for existing methods,including Regression models and Neural network models,to perform multi-characteristic coupled displacement prediction because they fail to consider landslide creep characteristics.This paper integrates the creep characteristics of landslides with non-linear intelligent algorithms and proposes a dynamic intelligent landslide displacement prediction method based on a combination of the Biological Growth model(BG),Convolutional Neural Network(CNN),and Long ShortTerm Memory Network(LSTM).This prediction approach improves three different biological growth models,thereby effectively extracting landslide creep characteristic parameters.Simultaneously,it integrates external factors(rainfall and reservoir water level)to construct an internal and external comprehensive dataset for data augmentation,which is input into the improved CNN-LSTM model.Thereafter,harnessing the robust feature extraction capabilities and spatial translation invariance of CNN,the model autonomously captures short-term local fluctuation characteristics of landslide displacement,and combines LSTM's efficient handling of long-term nonlinear temporal data to improve prediction performance.An evaluation of the Liangshuijing landslide in the Three Gorges Reservoir Area indicates that BG-CNN-LSTM exhibits high prediction accuracy,excellent generalization capabilities when dealing with various types of landslides.The research provides an innovative approach to achieving the whole-process,realtime,high-precision displacement predictions for multicharacteristic coupled landslides. 展开更多
关键词 Reservoir landslides Displacement prediction CNN LSTM Biological growth model
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Advancements and challenges in esophageal carcinoma prognostic models:A comprehensive review and future directions
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作者 Jia Chen Qi-Chang Xing 《World Journal of Gastrointestinal Oncology》 2025年第2期311-314,共4页
In this article,we comment on the article published by Yu et al.By employing LASSO regression and Cox proportional hazard models,the article identified nine significant variables affecting survival,including body mass... In this article,we comment on the article published by Yu et al.By employing LASSO regression and Cox proportional hazard models,the article identified nine significant variables affecting survival,including body mass index,Karnofsky performance status,and tumor-node-metastasis staging.We firmly concur with Yu et al regarding the vital significance of clinical prediction models(CPMs),including logistic regression and Cox regression for assessment in esophageal carcinoma(EC).However,the nomogram's limitations and the complexities of integrating genetic factors pose challenges.The integration of immunological data with advanced statistics offers new research directions.High-throughput sequencing and big data,facilitated by machine learning,have revolutionized cancer research but require substantial computational resources.The future of CPMs in EC depends on leveraging these technologies to improve predictive accuracy and clinical application,addressing the need for larger datasets,patientreported outcomes,and regular updates for clinical relevance. 展开更多
关键词 Predictive model Machine learning Esophageal carcinoma Survival rate FACTORS
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Assessing the possibility of using large language models in ocular surface diseases
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作者 Qian Ling Zi-Song Xu +11 位作者 Yan-Mei Zeng Qi Hong Xian-Zhe Qian Jin-Yu Hu Chong-Gang Pei Hong Wei Jie Zou Cheng Chen Xiao-Yu Wang Xu Chen Zhen-Kai Wu Yi Shao 《International Journal of Ophthalmology(English edition)》 2025年第1期1-8,共8页
AIM:To assess the possibility of using different large language models(LLMs)in ocular surface diseases by selecting five different LLMS to test their accuracy in answering specialized questions related to ocular surfa... AIM:To assess the possibility of using different large language models(LLMs)in ocular surface diseases by selecting five different LLMS to test their accuracy in answering specialized questions related to ocular surface diseases:ChatGPT-4,ChatGPT-3.5,Claude 2,PaLM2,and SenseNova.METHODS:A group of experienced ophthalmology professors were asked to develop a 100-question singlechoice question on ocular surface diseases designed to assess the performance of LLMs and human participants in answering ophthalmology specialty exam questions.The exam includes questions on the following topics:keratitis disease(20 questions),keratoconus,keratomalaciac,corneal dystrophy,corneal degeneration,erosive corneal ulcers,and corneal lesions associated with systemic diseases(20 questions),conjunctivitis disease(20 questions),trachoma,pterygoid and conjunctival tumor diseases(20 questions),and dry eye disease(20 questions).Then the total score of each LLMs and compared their mean score,mean correlation,variance,and confidence were calculated.RESULTS:GPT-4 exhibited the highest performance in terms of LLMs.Comparing the average scores of the LLMs group with the four human groups,chief physician,attending physician,regular trainee,and graduate student,it was found that except for ChatGPT-4,the total score of the rest of the LLMs is lower than that of the graduate student group,which had the lowest score in the human group.Both ChatGPT-4 and PaLM2 were more likely to give exact and correct answers,giving very little chance of an incorrect answer.ChatGPT-4 showed higher credibility when answering questions,with a success rate of 59%,but gave the wrong answer to the question 28% of the time.CONCLUSION:GPT-4 model exhibits excellent performance in both answer relevance and confidence.PaLM2 shows a positive correlation(up to 0.8)in terms of answer accuracy during the exam.In terms of answer confidence,PaLM2 is second only to GPT4 and surpasses Claude 2,SenseNova,and GPT-3.5.Despite the fact that ocular surface disease is a highly specialized discipline,GPT-4 still exhibits superior performance,suggesting that its potential and ability to be applied in this field is enormous,perhaps with the potential to be a valuable resource for medical students and clinicians in the future. 展开更多
关键词 ChatGPT-4.0 ChatGPT-3.5 large language models ocular surface diseases
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How Do Deep Learning Forecasting Models Perform for Surface Variables in the South China Sea Compared to Operational Oceanography Forecasting Systems?
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作者 Ziqing ZU Jiangjiang XIA +6 位作者 Xueming ZHU Marie DREVILLON Huier MO Xiao LOU Qian ZHOU Yunfei ZHANG Qing YANG 《Advances in Atmospheric Sciences》 2025年第1期178-189,共12页
It is fundamental and useful to investigate how deep learning forecasting models(DLMs)perform compared to operational oceanography forecast systems(OFSs).However,few studies have intercompared their performances using... It is fundamental and useful to investigate how deep learning forecasting models(DLMs)perform compared to operational oceanography forecast systems(OFSs).However,few studies have intercompared their performances using an identical reference.In this study,three physically reasonable DLMs are implemented for the forecasting of the sea surface temperature(SST),sea level anomaly(SLA),and sea surface velocity in the South China Sea.The DLMs are validated against both the testing dataset and the“OceanPredict”Class 4 dataset.Results show that the DLMs'RMSEs against the latter increase by 44%,245%,302%,and 109%for SST,SLA,current speed,and direction,respectively,compared to those against the former.Therefore,different references have significant influences on the validation,and it is necessary to use an identical and independent reference to intercompare the DLMs and OFSs.Against the Class 4 dataset,the DLMs present significantly better performance for SLA than the OFSs,and slightly better performances for other variables.The error patterns of the DLMs and OFSs show a high degree of similarity,which is reasonable from the viewpoint of predictability,facilitating further applications of the DLMs.For extreme events,the DLMs and OFSs both present large but similar forecast errors for SLA and current speed,while the DLMs are likely to give larger errors for SST and current direction.This study provides an evaluation of the forecast skills of commonly used DLMs and provides an example to objectively intercompare different DLMs. 展开更多
关键词 forecast error deep learning forecasting model operational oceanography forecasting system VALIDATION intercomparison
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Evaluating large language models as patient education tools for inflammatory bowel disease:A comparative study
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作者 Yan Zhang Xiao-Han Wan +6 位作者 Qing-Zhou Kong Han Liu Jun Liu Jing Guo Xiao-Yun Yang Xiu-Li Zuo Yan-Qing Li 《World Journal of Gastroenterology》 2025年第6期34-43,共10页
BACKGROUND Inflammatory bowel disease(IBD)is a global health burden that affects millions of individuals worldwide,necessitating extensive patient education.Large language models(LLMs)hold promise for addressing patie... BACKGROUND Inflammatory bowel disease(IBD)is a global health burden that affects millions of individuals worldwide,necessitating extensive patient education.Large language models(LLMs)hold promise for addressing patient information needs.However,LLM use to deliver accurate and comprehensible IBD-related medical information has yet to be thoroughly investigated.AIM To assess the utility of three LLMs(ChatGPT-4.0,Claude-3-Opus,and Gemini-1.5-Pro)as a reference point for patients with IBD.METHODS In this comparative study,two gastroenterology experts generated 15 IBD-related questions that reflected common patient concerns.These questions were used to evaluate the performance of the three LLMs.The answers provided by each model were independently assessed by three IBD-related medical experts using a Likert scale focusing on accuracy,comprehensibility,and correlation.Simultaneously,three patients were invited to evaluate the comprehensibility of their answers.Finally,a readability assessment was performed.RESULTS Overall,each of the LLMs achieved satisfactory levels of accuracy,comprehensibility,and completeness when answering IBD-related questions,although their performance varies.All of the investigated models demonstrated strengths in providing basic disease information such as IBD definition as well as its common symptoms and diagnostic methods.Nevertheless,when dealing with more complex medical advice,such as medication side effects,dietary adjustments,and complication risks,the quality of answers was inconsistent between the LLMs.Notably,Claude-3-Opus generated answers with better readability than the other two models.CONCLUSION LLMs have the potential as educational tools for patients with IBD;however,there are discrepancies between the models.Further optimization and the development of specialized models are necessary to ensure the accuracy and safety of the information provided. 展开更多
关键词 Inflammatory bowel disease Large language models Patient education Medical information accuracy Readability assessment
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基于DSGE模型的科技信贷激励政策研究 被引量:1
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作者 王慧 王子晗 刘微 《经济问题》 CSSCI 北大核心 2024年第8期85-94,共10页
通过构建基于全要素生产率厂商异质性的NK-DSGE(新凯恩斯—动态随机一般均衡)模型,模拟科技信贷激励政策的传导机制与政策效果,研究发现政策效果从大到小依次是常规货币政策、政府部门贴息、中央银行再贷款利率、中央银行定向降准、中... 通过构建基于全要素生产率厂商异质性的NK-DSGE(新凯恩斯—动态随机一般均衡)模型,模拟科技信贷激励政策的传导机制与政策效果,研究发现政策效果从大到小依次是常规货币政策、政府部门贴息、中央银行再贷款利率、中央银行定向降准、中央银行再贷款抵押率,与我国科技信贷激励政策的实践效果相吻合。进一步研究发现,政府贴息、再贷款利率的外生冲击波动幅度对政策效果影响弹性更大。建议地方政府应和银行加强联动,完善科技信贷风险补偿机制、贷款担保体系;另外,中国人民人行应加强常规货币政策实施精准性,并探索更加灵活的结构型货币政策机制。 展开更多
关键词 科技信贷政策 动态随机一般均衡模型 全要素生产率 厂商异质性
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商业银行普惠金融如何助力共同富裕目标实现?——引入异质性企业和家庭的BGG-DSGE模型分析 被引量:1
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作者 马晓青 童长凤 张小艳 《金融经济》 2024年第5期3-18,31,共17页
经济增长和收入分配改善是共同富裕的应有之义,也是实现共同富裕的重要途径。商业银行普惠金融以中小微企业和农民等弱势群体为主要服务对象,是推进共同富裕的重要力量。本文在包含BGG金融加速器的DSGE模型中引入异质性企业和异质性家庭... 经济增长和收入分配改善是共同富裕的应有之义,也是实现共同富裕的重要途径。商业银行普惠金融以中小微企业和农民等弱势群体为主要服务对象,是推进共同富裕的重要力量。本文在包含BGG金融加速器的DSGE模型中引入异质性企业和异质性家庭,从经济增长和收入分配角度分析商业银行普惠金融政策对共同富裕的动态一般均衡影响。校准参数后模拟发现,商业银行普惠金融政策会促进共同富裕。对比分析发现,宽松货币政策虽然会增加总产出,但会加剧收入不平等;同时,商业银行普惠金融政策和小企业技术进步的组合冲击更有利于实现共同富裕。 展开更多
关键词 普惠金融 共同富裕 BGG-dsge模型 货币政策效果 收入不平等
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碳中和目标下负排放策略的综合效应——基于N‑DSGE模型的数值模拟分析
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作者 沈维萍 夏克郁 陈迎 《中国人口·资源与环境》 CSSCI CSCD 北大核心 2024年第2期13-22,共10页
全球气候变化已达“气候紧急状态”,包括中国在内的诸多国家和地区先后宣布碳中和目标和净零排放承诺。在气候变化减缓和传统的适应措施之外,自然科学领域和气候经济学领域探讨负排放技术经济可行性的研究越来越多,但从可持续发展经济... 全球气候变化已达“气候紧急状态”,包括中国在内的诸多国家和地区先后宣布碳中和目标和净零排放承诺。在气候变化减缓和传统的适应措施之外,自然科学领域和气候经济学领域探讨负排放技术经济可行性的研究越来越多,但从可持续发展经济学视角对负排放技术综合效应的评估还比较少。该研究基于可持续发展经济学的生态价值理论,将气候变化综合评估模型与宏观经济学动态随机一般均衡(DSGE)模型相结合,构建包含自然生态系统部门的N‑DSGE模型,对负排放技术的气候效应、生态效应、经济效应以及福利效应进行综合评估。评估结果表明:①当可用技术条件下传统减排措施达到最大减排潜力后,可以依靠负排放技术实现净零排放乃至净负排放。②低强度、小规模实施负排放技术具有正向的气候、生态和经济效应,然而随着负排放技术实施强度增大,气候效应增强,经济效应削弱,社会综合福利明显降低。③敏感性分析证明了评估结果的稳健性,并进一步表明负排放技术的实施效果会受到传统减排水平和自然碳汇能力的影响。基于评估结果,应谨慎扩大负排放技术实施规模和实施强度,加强科学技术研发,降低技术成本;对不同负排放技术采取差异化发展策略;加强负排放技术实施的治理,尽可能避免和最小化其负面影响,促进气候、生态和经济等可持续发展目标的协同;部署负排放技术不应放松传统减排的努力,应降低碳达峰峰值,同时提升自然生态系统的碳汇能力。 展开更多
关键词 碳中和目标 负排放技术 N‑dsge模型 生态价值 福利效应
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灾难冲击、宏观经济稳定与货币政策选择——基于DSGE模型的决策效应分析
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作者 赵君 武凌曦 《陇东学院学报》 2024年第5期12-16,共5页
基于中国1992-2021年宏观经济统计数据,构建了包含全要素生产率灾害影响的新凯恩斯经济体动态随机一般均衡(DSGE)模型,并引入Calvo价格粘性、投资调整成本等因素,分析了数量型和价格型货币政策对我国宏观经济应对灾难冲击的调节效应。... 基于中国1992-2021年宏观经济统计数据,构建了包含全要素生产率灾害影响的新凯恩斯经济体动态随机一般均衡(DSGE)模型,并引入Calvo价格粘性、投资调整成本等因素,分析了数量型和价格型货币政策对我国宏观经济应对灾难冲击的调节效应。在灾难冲击下,我国宏观经济呈现短期下行态势,两种货币政策短期对经济均具有明显改善效应,长期均能促进经济恢复均衡状态。前者短期促进经济水平显著上升,但恢复均衡状态耗时较长。后者调节效应更加缓和,并且经济能够快速恢复其均衡值。因此,政府优化经济政策,相互协调配合,以应对灾难对宏观经济的冲击影响。 展开更多
关键词 灾难冲击 货币政策 dsge模型 价格粘性
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Anisotropic time-dependent behaviors of shale under direct shearing and associated empirical creep models 被引量:3
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作者 Yachen Xie Michael Z.Hou +1 位作者 Hejuan Liu Cunbao Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1262-1279,共18页
Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue.In this context,we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.0°,... Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue.In this context,we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.0°,30°,45°,60°,and 90°),under multiple levels of direct shearing for the first time.The results show that the anisotropic creep of shale exhibits a significant stress-dependent behavior.Under a low shear stress,the creep compliance of shale increases linearly with the logarithm of time at all bedding orientations,and the increase depends on the bedding orientation and creep time.Under high shear stress conditions,the creep compliance of shale is minimal when the bedding orientation is 0°,and the steady-creep rate of shale increases significantly with increasing bedding orientations of 30°,45°,60°,and 90°.The stress-strain values corresponding to the inception of the accelerated creep stage show an increasing and then decreasing trend with the bedding orientation.A semilogarithmic model that could reflect the stress dependence of the steady-creep rate while considering the hardening and damage process is proposed.The model minimizes the deviation of the calculated steady-state creep rate from the observed value and reveals the behavior of the bedding orientation's influence on the steady-creep rate.The applicability of the five classical empirical creep models is quantitatively evaluated.It shows that the logarithmic model can well explain the experimental creep strain and creep rate,and it can accurately predict long-term shear creep deformation.Based on an improved logarithmic model,the variations in creep parameters with shear stress and bedding orientations are discussed.With abovementioned findings,a mathematical method for constructing an anisotropic shear creep model of shale is proposed,which can characterize the nonlinear dependence of the anisotropic shear creep behavior of shale on the bedding orientation. 展开更多
关键词 Rock anisotropy Direct shear creep Creep compliance Steady-creep rate Empirical model Creep constitutive model
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数字基础设施对技术创新的区域异质性影响:基于DSGE模型的数值模拟
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作者 金海燕 李佩 《工程管理学报》 2024年第4期55-60,共6页
基于熊彼特创新理论和内生增长理论,构建考虑技术内生的动态随机一般均衡(Dynamic Stochastic General Equilibrium)模型,引入数字基础设施的两项冲击,通过参数校准和数值模拟,遵循“影响效应-传导机制-差异成因”的内在逻辑,揭示数字... 基于熊彼特创新理论和内生增长理论,构建考虑技术内生的动态随机一般均衡(Dynamic Stochastic General Equilibrium)模型,引入数字基础设施的两项冲击,通过参数校准和数值模拟,遵循“影响效应-传导机制-差异成因”的内在逻辑,揭示数字基础设施对不同区域技术创新与经济发展的作用规律。结果发现:数字基础设施对技术创新具有显著的驱动效应,其技术创新效应在中西部相对较强;驱动效应的传导路径具有区域差异:在东部主要由资本要素传导,在中西部主要由劳动要素传导;差异的可能成因包括客观资源禀赋不同导致的内源性差异、要素聚集规模不同导致的传导性差异和冲击作用时效不同导致的程度差异。研究为协调数字基础设施与创新资源配置、缩小区域发展差距提供理论和现实依据。 展开更多
关键词 数字基础设施 技术创新 区域经济发展 区域异质性 dsge模型
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Evolution and Prospects of Foundation Models: From Large Language Models to Large Multimodal Models 被引量:1
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作者 Zheyi Chen Liuchang Xu +5 位作者 Hongting Zheng Luyao Chen Amr Tolba Liang Zhao Keping Yu Hailin Feng 《Computers, Materials & Continua》 SCIE EI 2024年第8期1753-1808,共56页
Since the 1950s,when the Turing Test was introduced,there has been notable progress in machine language intelligence.Language modeling,crucial for AI development,has evolved from statistical to neural models over the ... Since the 1950s,when the Turing Test was introduced,there has been notable progress in machine language intelligence.Language modeling,crucial for AI development,has evolved from statistical to neural models over the last two decades.Recently,transformer-based Pre-trained Language Models(PLM)have excelled in Natural Language Processing(NLP)tasks by leveraging large-scale training corpora.Increasing the scale of these models enhances performance significantly,introducing abilities like context learning that smaller models lack.The advancement in Large Language Models,exemplified by the development of ChatGPT,has made significant impacts both academically and industrially,capturing widespread societal interest.This survey provides an overview of the development and prospects from Large Language Models(LLM)to Large Multimodal Models(LMM).It first discusses the contributions and technological advancements of LLMs in the field of natural language processing,especially in text generation and language understanding.Then,it turns to the discussion of LMMs,which integrates various data modalities such as text,images,and sound,demonstrating advanced capabilities in understanding and generating cross-modal content,paving new pathways for the adaptability and flexibility of AI systems.Finally,the survey highlights the prospects of LMMs in terms of technological development and application potential,while also pointing out challenges in data integration,cross-modal understanding accuracy,providing a comprehensive perspective on the latest developments in this field. 展开更多
关键词 Artificial intelligence large language models large multimodal models foundation models
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