Objectives:To date,no study provides a comprehensive analysis of traumatic orbital floor fractures across the United States.We aimed to characterize patient demographics,injury-related variables,and operative manageme...Objectives:To date,no study provides a comprehensive analysis of traumatic orbital floor fractures across the United States.We aimed to characterize patient demographics,injury-related variables,and operative management in this population.Method:The National Trauma Data Bank was queried for open or closed orbital floor fractures from 2008 to 2016.Clinical data were extracted.Results:Overall,148,592 orbital floor fractures were identified,with 142,577(95.9%)closed-and 6158(4.1%)open-type fractures.A total of 106,243(71.5%)patients were male and the median patient age was 41 years.The majority of patients(79.2%)had abbreviated injury scale scores of≤2,indicating minor/moderate injury.Fracture mechanism of injury(MOI)differed by gender,with the most frequent being unarmed fights in men(34.3%)and falls in women(14.0%).There were 29,600 patients(19.9%)with isolated orbital floor(I-OF)fractures.The MOI most strongly associated with operative intervention of with I-OF fractures were penetrating injuries caused by a firearm(odds ratio[OR]:2.91;95%confidence interval[CI]:1.62–5.20)and cuttings/piercings(OR:2.17;95%CI:1.29–3.65).Conclusion:This large epidemiological study reveals that orbital floor fractures tend to present with minor or moderate injuries and are more likely to require operative intervention in setting of firearm or cut/pierce injuries.展开更多
Blockchain is commonly considered a potentialdisruptive technology. Moreover, the healthcareindustry has experienced rapid growth in the adoption ofhealth information technology, such as electronic healthrecords and e...Blockchain is commonly considered a potentialdisruptive technology. Moreover, the healthcareindustry has experienced rapid growth in the adoption ofhealth information technology, such as electronic healthrecords and electronic medical records. To guarantee dataprivacy and data security as well as to harness the value ofhealth data, the concept of Health Data Bank (HDB) isproposed. In this study, HDB is defined as an integratedhealth data service institution, which bears no “ownership”of health data and operates health data under the principalagentmodel. This study first comprehensively reviews themain characters of blockchain and identifies the blockchain-based healthcare industry projects and startups in theareas of health insurance, pharmacy, and medical treatment.Then, we analyze the fundamental principles ofHDB and point out four challenges faced by HDB’ssustainable development: (1) privacy protection andinteroperability of health data;(2) data rights;(3) healthdata supervision;(4) and willingness to share health data.We also analyze the important benefits of blockchainadoption in HDB. Furthermore, three application scenariosincluding distributed storage of health data, smart-contractbasedhealthcare service mode, and consensus-algorithmbasedincentive policy are proposed to shed light on HDBbasedhealthcare service mode. In the end, this study offersinsights into potential research directions and challenges.展开更多
By the end of 2013, Chinese large-scaled commercial banks have basically completed the construction of IT banking system, in order to provide technical guarantee of deepening business operation and operation managemen...By the end of 2013, Chinese large-scaled commercial banks have basically completed the construction of IT banking system, in order to provide technical guarantee of deepening business operation and operation management reform. This indicates that our national banking industry information technology has been in a new level. This paper, based on the operation principle of commercial bank safety, liquidity and profitability, makes research on improving commercial banking profit data timeliness, accuracy, integrity and realizing daily accounting profit. According to survey, the four big banks have proposed the prospect of 2013 full scope implementing daily accounting profit. Thus, this paper, based on the profit accounting status of four big banks of data center, analyzes the feasibility of daily accounting profit and puts forward the relevant solutions.展开更多
蛋白质是一种具有空间结构的物质。蛋白质结构预测的主要目标是从已有的大规模的蛋白质数据集中提取有效的信息,从而预测自然界中蛋白质的结构。目前蛋白质结构预测实验存在的一个问题是,缺少能够进一步反映出蛋白质空间结构特征的数据...蛋白质是一种具有空间结构的物质。蛋白质结构预测的主要目标是从已有的大规模的蛋白质数据集中提取有效的信息,从而预测自然界中蛋白质的结构。目前蛋白质结构预测实验存在的一个问题是,缺少能够进一步反映出蛋白质空间结构特征的数据集。当前主流的PDB蛋白质数据集虽然是经过实验测得,但没有利用到蛋白质的空间特征,而且存在掺杂核酸数据和部分数据不完整的问题。针对以上问题,从蛋白质的空间结构角度来研究蛋白质的预测。在原始PDB数据集的基础上,提出了河海图结构蛋白质数据集(Hohai Graphic Protein Data Bank,HohaiGPDB)。该数据集以图结构为基础,表达出了蛋白质的空间结构特征。基于传统Transformer网络模型对新的数据集进行了相关的蛋白质结构预测实验,在HohaiGPDB数据集上的预测准确率可以达到59.38%,证明了HohaiGPDB数据集的研究价值。HohaiGPDB数据集可以作为蛋白质相关研究的通用数据集。展开更多
文摘Objectives:To date,no study provides a comprehensive analysis of traumatic orbital floor fractures across the United States.We aimed to characterize patient demographics,injury-related variables,and operative management in this population.Method:The National Trauma Data Bank was queried for open or closed orbital floor fractures from 2008 to 2016.Clinical data were extracted.Results:Overall,148,592 orbital floor fractures were identified,with 142,577(95.9%)closed-and 6158(4.1%)open-type fractures.A total of 106,243(71.5%)patients were male and the median patient age was 41 years.The majority of patients(79.2%)had abbreviated injury scale scores of≤2,indicating minor/moderate injury.Fracture mechanism of injury(MOI)differed by gender,with the most frequent being unarmed fights in men(34.3%)and falls in women(14.0%).There were 29,600 patients(19.9%)with isolated orbital floor(I-OF)fractures.The MOI most strongly associated with operative intervention of with I-OF fractures were penetrating injuries caused by a firearm(odds ratio[OR]:2.91;95%confidence interval[CI]:1.62–5.20)and cuttings/piercings(OR:2.17;95%CI:1.29–3.65).Conclusion:This large epidemiological study reveals that orbital floor fractures tend to present with minor or moderate injuries and are more likely to require operative intervention in setting of firearm or cut/pierce injuries.
基金the National Natural Science Foundation of China(Grant No.71671039).
文摘Blockchain is commonly considered a potentialdisruptive technology. Moreover, the healthcareindustry has experienced rapid growth in the adoption ofhealth information technology, such as electronic healthrecords and electronic medical records. To guarantee dataprivacy and data security as well as to harness the value ofhealth data, the concept of Health Data Bank (HDB) isproposed. In this study, HDB is defined as an integratedhealth data service institution, which bears no “ownership”of health data and operates health data under the principalagentmodel. This study first comprehensively reviews themain characters of blockchain and identifies the blockchain-based healthcare industry projects and startups in theareas of health insurance, pharmacy, and medical treatment.Then, we analyze the fundamental principles ofHDB and point out four challenges faced by HDB’ssustainable development: (1) privacy protection andinteroperability of health data;(2) data rights;(3) healthdata supervision;(4) and willingness to share health data.We also analyze the important benefits of blockchainadoption in HDB. Furthermore, three application scenariosincluding distributed storage of health data, smart-contractbasedhealthcare service mode, and consensus-algorithmbasedincentive policy are proposed to shed light on HDBbasedhealthcare service mode. In the end, this study offersinsights into potential research directions and challenges.
文摘By the end of 2013, Chinese large-scaled commercial banks have basically completed the construction of IT banking system, in order to provide technical guarantee of deepening business operation and operation management reform. This indicates that our national banking industry information technology has been in a new level. This paper, based on the operation principle of commercial bank safety, liquidity and profitability, makes research on improving commercial banking profit data timeliness, accuracy, integrity and realizing daily accounting profit. According to survey, the four big banks have proposed the prospect of 2013 full scope implementing daily accounting profit. Thus, this paper, based on the profit accounting status of four big banks of data center, analyzes the feasibility of daily accounting profit and puts forward the relevant solutions.
文摘蛋白质是一种具有空间结构的物质。蛋白质结构预测的主要目标是从已有的大规模的蛋白质数据集中提取有效的信息,从而预测自然界中蛋白质的结构。目前蛋白质结构预测实验存在的一个问题是,缺少能够进一步反映出蛋白质空间结构特征的数据集。当前主流的PDB蛋白质数据集虽然是经过实验测得,但没有利用到蛋白质的空间特征,而且存在掺杂核酸数据和部分数据不完整的问题。针对以上问题,从蛋白质的空间结构角度来研究蛋白质的预测。在原始PDB数据集的基础上,提出了河海图结构蛋白质数据集(Hohai Graphic Protein Data Bank,HohaiGPDB)。该数据集以图结构为基础,表达出了蛋白质的空间结构特征。基于传统Transformer网络模型对新的数据集进行了相关的蛋白质结构预测实验,在HohaiGPDB数据集上的预测准确率可以达到59.38%,证明了HohaiGPDB数据集的研究价值。HohaiGPDB数据集可以作为蛋白质相关研究的通用数据集。
基金supported by the National Key Research and Development Program of China (2021YFA1301504)the National Natural Science Foundation of China (91953101)the Chinese Academy of Sciences Strategic Priority Research Program (XDB37040202)。