Hemodynamic low-frequency(~0.1 Hz)spontaneous oscillations as detected in the brain by nearinfrared spectroscopy have potential applications in the study of brain activation,cerebral autoregulation,and functional conn...Hemodynamic low-frequency(~0.1 Hz)spontaneous oscillations as detected in the brain by nearinfrared spectroscopy have potential applications in the study of brain activation,cerebral autoregulation,and functional connectivity.In this work,we have investigated the phase lag between oscillations of cerebral deoxy-and oxy-hemoglobin concentrations in the frequency range 0.05-0.10 Hz in a human subject during a mental workload task.We have obtained a measure of such phase lag using two different methods:(1)phase synchronization analysis as used in the theory of chaotic oscillators and(2)a novel cross-correlation phasor approach.The two methods yielded comparable initial results of a larger phase lag between low-frequency oscillations of deoxy-and oxyhemoglobin concentrations during mental workload with respect to a control,rest condition.展开更多
基金This research is supported by NIH Grant R01-NS059933 and by NSF Award IIS-0713506.
文摘Hemodynamic low-frequency(~0.1 Hz)spontaneous oscillations as detected in the brain by nearinfrared spectroscopy have potential applications in the study of brain activation,cerebral autoregulation,and functional connectivity.In this work,we have investigated the phase lag between oscillations of cerebral deoxy-and oxy-hemoglobin concentrations in the frequency range 0.05-0.10 Hz in a human subject during a mental workload task.We have obtained a measure of such phase lag using two different methods:(1)phase synchronization analysis as used in the theory of chaotic oscillators and(2)a novel cross-correlation phasor approach.The two methods yielded comparable initial results of a larger phase lag between low-frequency oscillations of deoxy-and oxyhemoglobin concentrations during mental workload with respect to a control,rest condition.
