The Third Plenary Session of the 16th Central Committee of the Communist Party of China (CPC) in October 2003 put forward a scientific approach of people-centered, all-round, coordinated and sustainable development ...The Third Plenary Session of the 16th Central Committee of the Communist Party of China (CPC) in October 2003 put forward a scientific approach of people-centered, all-round, coordinated and sustainable development and made it a strategy for governing the country, putting it in command of all economic and social development. Since reform and opening up in 1978, China has persisted in the central task of economic development and put development in the first place. The evolution of the concept "development is the hard truth" to "development is a task of first importance in governing the country and invigorating the Chinese nation" and to the establishment of the scientific development approach reflects the deepening and growing command of the laws governing China's economic and social development.展开更多
Schwann cells are the myelinating glial cells of the peripheral nervous system(PNS).By establishing lipid-rich myelin sheaths around large-caliber axons,they ensure that electrical signal transmission is accelerated...Schwann cells are the myelinating glial cells of the peripheral nervous system(PNS).By establishing lipid-rich myelin sheaths around large-caliber axons,they ensure that electrical signal transmission is accelerated-a process referred to as saltatory signal propagation.Apart from this prominent physiological function,these cells also exert important pathophysiological roles in PNS injuries or dis- eases. In contrast to the central nervous system (CNS), the adult PNS retains a remarkably high degree of intrinsic re- generation. As a consequence, transected axons and dam- aged myelin sheaths can be repaired and nerve functional- ity can be restored. This spontaneous regenerative capacity depends on (inter) actions of macrophages, neurons, and Schwann cells.展开更多
In the late 1970s,China firmly resolved upon a path of re- form and opening up to the outside world under a heightened sense of crisis stemming from the tremendous gap between China and developed countries in terms of...In the late 1970s,China firmly resolved upon a path of re- form and opening up to the outside world under a heightened sense of crisis stemming from the tremendous gap between China and developed countries in terms of economic development.China chose to accelerate industrialization in order to narrow this gap, but the cost of doing so is reflected primarily in the展开更多
Both being two developing countries with a vast territory, dense population, and centuries-old ancient civilization, China and India have many in common in natural resources, population size, historical condition, cur...Both being two developing countries with a vast territory, dense population, and centuries-old ancient civilization, China and India have many in common in natural resources, population size, historical condition, current economic issues, etc. except for regime. The competition between China and India is a typical one between economic institutions. This paper, by making a diachronic analysis on their courses of development, tries to justify the importance of adopting an economic institution suitable to the situation of a country.展开更多
At present,China is the world’s largest consumer of iron ore, nickel,copper,steel,coal and cement,and the world’s second largest consumer of oil,alumina,electricity and energy.Currently, China is creating 4~5% of t...At present,China is the world’s largest consumer of iron ore, nickel,copper,steel,coal and cement,and the world’s second largest consumer of oil,alumina,electricity and energy.Currently, China is creating 4~5% of the world’s GDP by consuming 8.92% of the world’s oil,32.1% of raw coal,30.7% of iron ore,28% of steel.20% of alumina and 50% of cement.展开更多
BACKGROUND The standard management of autoimmune hepatitis(AIH)is based on corticosteroids,alone or in combination with azathioprine.Second-line treatments are needed for patients who have refractory disease.However,h...BACKGROUND The standard management of autoimmune hepatitis(AIH)is based on corticosteroids,alone or in combination with azathioprine.Second-line treatments are needed for patients who have refractory disease.However,high-quality data on the alternative management of AIH are scarce.AIM To evaluate the efficacy and safety of tacrolimus and mycophenolate mofetil(MMF)and the quality of evidence by using the Grading of Recommendations Assessment,Development and Evaluation approach(GRADE).METHODS A systematic review and meta-analysis of the available data were performed.We calculated pooled event rates for three outcome measures:Biochemical remission,adverse events,and mortality,with their corresponding 95%confidence intervals(CI).RESULTS The pooled biochemical remission rate was 68.9%(95%CI:60.4-76.2)for tacrolimus,and 59.6%(95%CI:54.8-64.2)for MMF,and rates of adverse events were 25.5%(95%CI:12.4-45.3)for tacrolimus and 24.1%(95%CI:15.4-35.7)for MMF.The pooled mortality rate was estimated at 11.5%(95%CI:7.1-18.1)for tacrolimus and 9.01%(95%CI:6.2-12.8)for MMF.Pooled biochemical remission rates for tacrolimus and MMF in patients with intolerance to standard therapy were 56.6%(CI:43.4-56.6)vs 73.5%(CI:58.1-84.7),and among non-responders were 59.1%(CI:48.7-68.8)vs 40.8%(CI:32.3-50.0),respectively.Moreover,the overall quality assessments using GRADE proved to be very low for all our outcomes in both treatment groups.CONCLUSION Tacrolimus and MMF are in practice considered effective for patients with AIH who are non-responders or intolerant to first-line treatment,but we found no high-quality evidence to support this statement.展开更多
Dimensions in breadth (to be or not to be): presence or absence. Dimensions of being (to be and to have): essential sens of existence. Dimensions of prospective (inspiration and reason): needs and wishes.Dime...Dimensions in breadth (to be or not to be): presence or absence. Dimensions of being (to be and to have): essential sens of existence. Dimensions of prospective (inspiration and reason): needs and wishes.Dimensions offacts (minute and, or, assembled): irrefutable reasoning and logic. Dimensions of deeds (track record and recognition): proof and ease. Dimensions of values (precise and or wide): religious convictions and truths.Multicultural appreciation: life experience, knowledge, and awareness. Single or Multiple: individual freedom, or multiplied treasons. Monovoiced and scope (melody and harmony).Vertical, lateral, and open-ended (toward the future): for work afield, in spirit and Time. Broad market returns [hedge-funds (markets are slower than finances, hence manageable)]. Today's philosophy [Paul Ricoeur (1913-2005) (Theologean and Philosopher)]: might primarily be adapted and worked to a Western civilization!展开更多
At the beginning, this paper briefly introduces the evolution of information system development approach (ISDA), which can be divided into five categories: life cycle approach (LCA), structured approach (SA),prototypi...At the beginning, this paper briefly introduces the evolution of information system development approach (ISDA), which can be divided into five categories: life cycle approach (LCA), structured approach (SA),prototyping approach (PA), object oriented approach (OOA) and soft system methodology (SSM). After we make a comparative analysis of them,the main factors resulting in failure of information system development (ISD) in China are explained in detail. Consequently, such an assertion that false selection of unsuitable ISDA is the most important reason leading to unsuccessful ISD is reached. In order to avoid it, based on the fuzzy decision making theory, this article demonstrates a method of evaluating alternative ISDAes to select relatively satisfactory one out of them, for which a fuzzy synthetic discrimination model is created. In particular, a typical summarized evaluation index system is established, too. Finally, the application of the above method to a practical information system (IS) is illustrated.展开更多
As the name reflects, integrative plant biology is the core topic of JIPB. In the past few years JIPB has been pursuing the development of this area, to assist the scientific community to bring together all possible r...As the name reflects, integrative plant biology is the core topic of JIPB. In the past few years JIPB has been pursuing the development of this area, to assist the scientific community to bring together all possible research tools to understand plant growth, development and stress responses in micro- and macro-scales. As part of these efforts, JIPB and Yantai University organized the 1st International Symposium on Integrative Plant Biology in the seaside town of Yantai during August 10-12, 2009 (Figure 1) The symposium was co-sponsored by Botanical Society of China, Chinese Society for Cell Biology, Genetics Society of China, and Chinese Society for Plant Physiology.展开更多
A domain knowledge driven user interface development approach is described.As a conceptual de- sign of the user interface,the domain knowledge defines the user interface in terms of objects,actions and their relations...A domain knowledge driven user interface development approach is described.As a conceptual de- sign of the user interface,the domain knowledge defines the user interface in terms of objects,actions and their relationships that the user would use to interact with the application system.It also serves as input to a user interface management system(UIMS)and is the kernel of the target user interface. The principal ideas and the implementation techniques of the approach is discussed.The user interface model,user interface designer oriented high-level specification notation,and the transformation algorithms on domain knowledge are presented.展开更多
A paradigm of program development using type theories is given after analyzing some typical exam- ples.In order to carry this approach forward,a language ALT is designed.It is a linguistic description of a generalized...A paradigm of program development using type theories is given after analyzing some typical exam- ples.In order to carry this approach forward,a language ALT is designed.It is a linguistic description of a generalized higher order typed lambda calculus with Π,∑ types and Π,∑ kinds (supertypes). Four examples are given to show how ALT can be used to implement many concepts of software engi- neering and artificial intelligence.They are intuitionistic logic,Peano arithmetic,approximate reasoning and program transformations.ALT is described formally,using a structural operational approach.展开更多
文摘The Third Plenary Session of the 16th Central Committee of the Communist Party of China (CPC) in October 2003 put forward a scientific approach of people-centered, all-round, coordinated and sustainable development and made it a strategy for governing the country, putting it in command of all economic and social development. Since reform and opening up in 1978, China has persisted in the central task of economic development and put development in the first place. The evolution of the concept "development is the hard truth" to "development is a task of first importance in governing the country and invigorating the Chinese nation" and to the establishment of the scientific development approach reflects the deepening and growing command of the laws governing China's economic and social development.
基金supported by grants from the DFG(German Research Council)Novartis Pharma Gmb H(Nürnberg+2 种基金Germany)Baxter Innovations Gmb H(ViennaGermany)
文摘Schwann cells are the myelinating glial cells of the peripheral nervous system(PNS).By establishing lipid-rich myelin sheaths around large-caliber axons,they ensure that electrical signal transmission is accelerated-a process referred to as saltatory signal propagation.Apart from this prominent physiological function,these cells also exert important pathophysiological roles in PNS injuries or dis- eases. In contrast to the central nervous system (CNS), the adult PNS retains a remarkably high degree of intrinsic re- generation. As a consequence, transected axons and dam- aged myelin sheaths can be repaired and nerve functional- ity can be restored. This spontaneous regenerative capacity depends on (inter) actions of macrophages, neurons, and Schwann cells.
文摘In the late 1970s,China firmly resolved upon a path of re- form and opening up to the outside world under a heightened sense of crisis stemming from the tremendous gap between China and developed countries in terms of economic development.China chose to accelerate industrialization in order to narrow this gap, but the cost of doing so is reflected primarily in the
文摘Both being two developing countries with a vast territory, dense population, and centuries-old ancient civilization, China and India have many in common in natural resources, population size, historical condition, current economic issues, etc. except for regime. The competition between China and India is a typical one between economic institutions. This paper, by making a diachronic analysis on their courses of development, tries to justify the importance of adopting an economic institution suitable to the situation of a country.
文摘At present,China is the world’s largest consumer of iron ore, nickel,copper,steel,coal and cement,and the world’s second largest consumer of oil,alumina,electricity and energy.Currently, China is creating 4~5% of the world’s GDP by consuming 8.92% of the world’s oil,32.1% of raw coal,30.7% of iron ore,28% of steel.20% of alumina and 50% of cement.
文摘BACKGROUND The standard management of autoimmune hepatitis(AIH)is based on corticosteroids,alone or in combination with azathioprine.Second-line treatments are needed for patients who have refractory disease.However,high-quality data on the alternative management of AIH are scarce.AIM To evaluate the efficacy and safety of tacrolimus and mycophenolate mofetil(MMF)and the quality of evidence by using the Grading of Recommendations Assessment,Development and Evaluation approach(GRADE).METHODS A systematic review and meta-analysis of the available data were performed.We calculated pooled event rates for three outcome measures:Biochemical remission,adverse events,and mortality,with their corresponding 95%confidence intervals(CI).RESULTS The pooled biochemical remission rate was 68.9%(95%CI:60.4-76.2)for tacrolimus,and 59.6%(95%CI:54.8-64.2)for MMF,and rates of adverse events were 25.5%(95%CI:12.4-45.3)for tacrolimus and 24.1%(95%CI:15.4-35.7)for MMF.The pooled mortality rate was estimated at 11.5%(95%CI:7.1-18.1)for tacrolimus and 9.01%(95%CI:6.2-12.8)for MMF.Pooled biochemical remission rates for tacrolimus and MMF in patients with intolerance to standard therapy were 56.6%(CI:43.4-56.6)vs 73.5%(CI:58.1-84.7),and among non-responders were 59.1%(CI:48.7-68.8)vs 40.8%(CI:32.3-50.0),respectively.Moreover,the overall quality assessments using GRADE proved to be very low for all our outcomes in both treatment groups.CONCLUSION Tacrolimus and MMF are in practice considered effective for patients with AIH who are non-responders or intolerant to first-line treatment,but we found no high-quality evidence to support this statement.
文摘Dimensions in breadth (to be or not to be): presence or absence. Dimensions of being (to be and to have): essential sens of existence. Dimensions of prospective (inspiration and reason): needs and wishes.Dimensions offacts (minute and, or, assembled): irrefutable reasoning and logic. Dimensions of deeds (track record and recognition): proof and ease. Dimensions of values (precise and or wide): religious convictions and truths.Multicultural appreciation: life experience, knowledge, and awareness. Single or Multiple: individual freedom, or multiplied treasons. Monovoiced and scope (melody and harmony).Vertical, lateral, and open-ended (toward the future): for work afield, in spirit and Time. Broad market returns [hedge-funds (markets are slower than finances, hence manageable)]. Today's philosophy [Paul Ricoeur (1913-2005) (Theologean and Philosopher)]: might primarily be adapted and worked to a Western civilization!
文摘At the beginning, this paper briefly introduces the evolution of information system development approach (ISDA), which can be divided into five categories: life cycle approach (LCA), structured approach (SA),prototyping approach (PA), object oriented approach (OOA) and soft system methodology (SSM). After we make a comparative analysis of them,the main factors resulting in failure of information system development (ISD) in China are explained in detail. Consequently, such an assertion that false selection of unsuitable ISDA is the most important reason leading to unsuccessful ISD is reached. In order to avoid it, based on the fuzzy decision making theory, this article demonstrates a method of evaluating alternative ISDAes to select relatively satisfactory one out of them, for which a fuzzy synthetic discrimination model is created. In particular, a typical summarized evaluation index system is established, too. Finally, the application of the above method to a practical information system (IS) is illustrated.
文摘As the name reflects, integrative plant biology is the core topic of JIPB. In the past few years JIPB has been pursuing the development of this area, to assist the scientific community to bring together all possible research tools to understand plant growth, development and stress responses in micro- and macro-scales. As part of these efforts, JIPB and Yantai University organized the 1st International Symposium on Integrative Plant Biology in the seaside town of Yantai during August 10-12, 2009 (Figure 1) The symposium was co-sponsored by Botanical Society of China, Chinese Society for Cell Biology, Genetics Society of China, and Chinese Society for Plant Physiology.
基金The project is supported by National Natural Science Foundation of China.
文摘A domain knowledge driven user interface development approach is described.As a conceptual de- sign of the user interface,the domain knowledge defines the user interface in terms of objects,actions and their relationships that the user would use to interact with the application system.It also serves as input to a user interface management system(UIMS)and is the kernel of the target user interface. The principal ideas and the implementation techniques of the approach is discussed.The user interface model,user interface designer oriented high-level specification notation,and the transformation algorithms on domain knowledge are presented.
文摘A paradigm of program development using type theories is given after analyzing some typical exam- ples.In order to carry this approach forward,a language ALT is designed.It is a linguistic description of a generalized higher order typed lambda calculus with Π,∑ types and Π,∑ kinds (supertypes). Four examples are given to show how ALT can be used to implement many concepts of software engi- neering and artificial intelligence.They are intuitionistic logic,Peano arithmetic,approximate reasoning and program transformations.ALT is described formally,using a structural operational approach.