肾脏黏液性小管状和梭形细胞癌(mucinous tubular and spindlecell carcinoma,MTSCCa)是新确定一种罕见的低度恶性肾上皮性肿瘤。多见于青年女性,临床上无明显症状。以往常被诊断为梭形细胞(肉瘤样)肾细胞癌或不能分类的肾细胞癌。大体...肾脏黏液性小管状和梭形细胞癌(mucinous tubular and spindlecell carcinoma,MTSCCa)是新确定一种罕见的低度恶性肾上皮性肿瘤。多见于青年女性,临床上无明显症状。以往常被诊断为梭形细胞(肉瘤样)肾细胞癌或不能分类的肾细胞癌。大体肿物界限清楚,切面实性、灰白色。组织学特点是肿瘤细胞排列成管状和实性梁索状漂浮于黏液性基质中,Alcianblue染色阳性。免疫组化显示复合性免疫表型。临床预后好,可复发并具有潜在远处转移的可能,应重视与其他肾脏良恶性肿瘤(后肾腺瘤、肉瘤样癌和集合管癌等)相鉴别。展开更多
Thermo-sensitive genic male sterile （TGMS） lines have specific superiority in heterosis utilization of crops. So far, thermo-sensitive genic male sterile lines have been found in many plants and are widely used in t...Thermo-sensitive genic male sterile （TGMS） lines have specific superiority in heterosis utilization of crops. So far, thermo-sensitive genic male sterile lines have been found in many plants and are widely used in two-line hybrid breeding. With the rapid development of molecular biology, the molecular nature of thermo-sensitive genic male sterility has been revealed, which lays the foundation for further devel- opment and utilization of thermo-sensitive genic male sterile lines. In this study, the molecular mechanisms of fertility conversion of plant thermo-sensitive genic male sterile lines were reviewed from gene molecular mapping and gene differential ex- pression, and the mechanisms of gene differential expression in thermo-sensitive genic male sterile lines were further discussed.展开更多
In this paper, for the unbalanced Feistel network which employs diffusion matrices in a switching way, we study the fixed number of its differential active S-boxes. Firstly we obtain some lower bounds of the different...In this paper, for the unbalanced Feistel network which employs diffusion matrices in a switching way, we study the fixed number of its differential active S-boxes. Firstly we obtain some lower bounds of the differential active S-boxes for m, 2m and 3m rounds of Feistel structure, respectively. By concatenating these rounds, a fixed number of differential active S-boxes for arbitrary round number is derived. Our results imply that the unbalanced Feistel network using DSM is more secure than the traditional structure.展开更多
目的探讨儿童难治性血细胞减少（refractory cytopenia of children，RCC）的诊断及鉴别诊断，并评价骨髓穿刺和活检在RCC诊断中的作用。方法回顾性分析2007至2010年间50例临床诊断为非重型再生障碍性贫血（AA）患儿的临床资料，复查骨...目的探讨儿童难治性血细胞减少（refractory cytopenia of children，RCC）的诊断及鉴别诊断，并评价骨髓穿刺和活检在RCC诊断中的作用。方法回顾性分析2007至2010年间50例临床诊断为非重型再生障碍性贫血（AA）患儿的临床资料，复查骨髓穿刺涂片、骨髓活检、血常规及免疫组化等实验室检查，根据骨髓增生异常综合征WHO分类标准（2008版）重新评估儿童全血细胞减少中RCC的诊断及相关的鉴别诊断。结果50例患儿中男23例、女27例（男：女=1：1．17），诊断时中位年龄9（3—14）岁。骨髓穿刺涂片与骨髓活检诊断不一致的共有5例，其中3例涂片诊断为AA，活检诊断为RCC，2例反之。结合骨髓穿刺涂片和活检结果，最终诊断AA16例、RCC34例[其中8例为难治性血细胞减少伴多系发育异常（RCMD）]。全部16例AA患者骨髓增生极度低下，RCC中有4例（15．38％）、RCMD有5例（62．50％）骨髓增生极度低下，RCC中有19例（73．08％）、RCMD中有2例（25．00％）骨髓增生较低下，RCC中有3例（11．54％）、RCMD有1例（12．50％）骨髓增生正常。结论RCC骨髓原始细胞数并不增多，病态造血是主要特征。RCC与AA鉴别诊断要点：有否病态造血及程度、造血细胞的异常分布及定位、巨核细胞的形态特点等。AA与RCC患者鉴别诊断须骨髓穿刺涂片和活检两种检查手段互为补充。展开更多
文摘肾脏黏液性小管状和梭形细胞癌(mucinous tubular and spindlecell carcinoma,MTSCCa)是新确定一种罕见的低度恶性肾上皮性肿瘤。多见于青年女性,临床上无明显症状。以往常被诊断为梭形细胞(肉瘤样)肾细胞癌或不能分类的肾细胞癌。大体肿物界限清楚,切面实性、灰白色。组织学特点是肿瘤细胞排列成管状和实性梁索状漂浮于黏液性基质中,Alcianblue染色阳性。免疫组化显示复合性免疫表型。临床预后好,可复发并具有潜在远处转移的可能,应重视与其他肾脏良恶性肿瘤(后肾腺瘤、肉瘤样癌和集合管癌等)相鉴别。
基金Supported by National Natural Science Foundation of China (31160289)~~
文摘Thermo-sensitive genic male sterile （TGMS） lines have specific superiority in heterosis utilization of crops. So far, thermo-sensitive genic male sterile lines have been found in many plants and are widely used in two-line hybrid breeding. With the rapid development of molecular biology, the molecular nature of thermo-sensitive genic male sterility has been revealed, which lays the foundation for further devel- opment and utilization of thermo-sensitive genic male sterile lines. In this study, the molecular mechanisms of fertility conversion of plant thermo-sensitive genic male sterile lines were reviewed from gene molecular mapping and gene differential ex- pression, and the mechanisms of gene differential expression in thermo-sensitive genic male sterile lines were further discussed.
基金Supported by the National Natural Science Foundation of China(11204379)Innovation Scientists and Technicians Troop Construction Projects of Henan Province(104100510025)
文摘In this paper, for the unbalanced Feistel network which employs diffusion matrices in a switching way, we study the fixed number of its differential active S-boxes. Firstly we obtain some lower bounds of the differential active S-boxes for m, 2m and 3m rounds of Feistel structure, respectively. By concatenating these rounds, a fixed number of differential active S-boxes for arbitrary round number is derived. Our results imply that the unbalanced Feistel network using DSM is more secure than the traditional structure.
文摘目的探讨儿童难治性血细胞减少（refractory cytopenia of children，RCC）的诊断及鉴别诊断，并评价骨髓穿刺和活检在RCC诊断中的作用。方法回顾性分析2007至2010年间50例临床诊断为非重型再生障碍性贫血（AA）患儿的临床资料，复查骨髓穿刺涂片、骨髓活检、血常规及免疫组化等实验室检查，根据骨髓增生异常综合征WHO分类标准（2008版）重新评估儿童全血细胞减少中RCC的诊断及相关的鉴别诊断。结果50例患儿中男23例、女27例（男：女=1：1．17），诊断时中位年龄9（3—14）岁。骨髓穿刺涂片与骨髓活检诊断不一致的共有5例，其中3例涂片诊断为AA，活检诊断为RCC，2例反之。结合骨髓穿刺涂片和活检结果，最终诊断AA16例、RCC34例[其中8例为难治性血细胞减少伴多系发育异常（RCMD）]。全部16例AA患者骨髓增生极度低下，RCC中有4例（15．38％）、RCMD有5例（62．50％）骨髓增生极度低下，RCC中有19例（73．08％）、RCMD中有2例（25．00％）骨髓增生较低下，RCC中有3例（11．54％）、RCMD有1例（12．50％）骨髓增生正常。结论RCC骨髓原始细胞数并不增多，病态造血是主要特征。RCC与AA鉴别诊断要点：有否病态造血及程度、造血细胞的异常分布及定位、巨核细胞的形态特点等。AA与RCC患者鉴别诊断须骨髓穿刺涂片和活检两种检查手段互为补充。
