To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, a modified algorithm is proposed for calculating these parameters. Magnetic resonance (MR) diffusion tensor images...To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, a modified algorithm is proposed for calculating these parameters. Magnetic resonance (MR) diffusion tensor images of five healthy volunteers are collected. The diffusion sensitive gradient magnetic fields are applied along 25 directions and the diffusion weighting value is 1 000 s/mm^2. Many positive-indefinite diffusion tensors can be found in the white matter area, such as the genu and the splenium of corpus callosum. Due to the positive-indefinite matrix, the mean diffusivity (MD) and the fractional anisotropy (FA) are under-estimated and over-estimated by using the conventional algorithm. Thus, the conventional algorithm is modified by using the absolute values of all eigenvalues. Results show that both the robustness and the reliability for deriving these parameters are improved by the modified algorithm.展开更多
This paper investigates the existence of periodic solutions of a three-species food-chain diffusive system with Beddington-DeAngelis functional responses and time delays in a two-patch environment on time scales. By u...This paper investigates the existence of periodic solutions of a three-species food-chain diffusive system with Beddington-DeAngelis functional responses and time delays in a two-patch environment on time scales. By using a continuation theorem based on coincidence degree theory, we obtain sufficient criteria for the existence of periodic solutions for the system. Moreover, when the time scale T is chosen as R or Z, the existence of the periodic solutions of the corresponding continuous and discrete models follows. Therefore, the method is unified to provide the existence of the desired solutions for continuous differential equations and discrete difference equations.展开更多
A new algorithm is presented by using the ant colony algorithm based on genetic method (ACG) to solve the continuous optimization problem. Each component has a seed set. The seed in the set has the value of componen...A new algorithm is presented by using the ant colony algorithm based on genetic method (ACG) to solve the continuous optimization problem. Each component has a seed set. The seed in the set has the value of component, trail information and fitness. The ant chooses a seed from the seed set with the possibility determined by trail information and fitness of the seed. The genetic method is used to form new solutions from the solutions got by the ants. Best solutions are selected to update the seeds in the sets and trail information of the seeds. In updating the trail information, a diffusion function is used to achieve the diffuseness of trail information. The new algorithm is tested with 8 different benchmark functions.展开更多
When DR (Digital Radiography) images are filtered, it is necessary to preserve the edges and key details. But the existing methods may inevitably take fine details mistaken for noise to remove. In order to solve the...When DR (Digital Radiography) images are filtered, it is necessary to preserve the edges and key details. But the existing methods may inevitably take fine details mistaken for noise to remove. In order to solve the problem an improved anisotropic diffu- sion filtering model is proposed. Firstly, a novel diffusion function is introduced based on Perona and Malik model, which well overcomes the high rate of convergence. Secondly, the gradient threshold is modified to an adaptive estimation function, so it is bet- ter at adaptive threshold regulations according to the pixels and iteration times. Finally, the edges are extracted from the restored im- ages and the results are evaluated quantificationally. It is shown from the experiments that the proposed method is effective not only in noise reduction but also in details preserved.展开更多
In this paper, we present a new scheme to segment a given image. This scheme utilizes neuro-fuzzy system to derive a proper set of contour pixels based on multi-scale images. We use these fuzzy derivatives to develop ...In this paper, we present a new scheme to segment a given image. This scheme utilizes neuro-fuzzy system to derive a proper set of contour pixels based on multi-scale images. We use these fuzzy derivatives to develop a new curve evolution model. The model automatically detect smooth boundaries, scaling the energy term, and change of topology according to the extracted con- tour pixels set. We present the numerical implementation and the experimental results based on the semi-implicit method. Experi- mental results show that one can obtains a high clualitv edge contour.展开更多
Fractional calculus and special functions have contributed a lot to mathematical physics and its various branches. The great use of mathematical physics in distinguished astrophysical problems has attracted astronomer...Fractional calculus and special functions have contributed a lot to mathematical physics and its various branches. The great use of mathematical physics in distinguished astrophysical problems has attracted astronomers and physicists to pay more attention to available mathematical tools that can be widely used in solving several problems of astrophysics/physics. In view of the great importance and usefulness of kinetic equations in certain astrophysical problems, the authors derive a generalized fractional kinetic equation involving the Lorenzo-Hartley function, a generalized function for fractional calculus. The fractional kinetic equation discussed here can be used to investigate a wide class of known (and possibly also new) fractional kinetic equations, hitherto scattered in the literature. A compact and easily computable solution is established in terms of the Lorenzo-Hartley function. Special cases, involving the generalized Mittag-Leffler function and the R-function, are considered. The obtained results imply the known results more precisely.展开更多
Divergences of the single reference perturbation theories due to the addition of diffusion basis functions have been investigated for both closed-shell and open-shell molecular systems. It is found that the oscillator...Divergences of the single reference perturbation theories due to the addition of diffusion basis functions have been investigated for both closed-shell and open-shell molecular systems. It is found that the oscillatory range of perturbation energies of open-shell systems increases as the spin multiplicity of systems changes from 2 to 4. Feenberg transformation is exploited to treat the divergence problems. It is found numerically that within the interval of Feenberg parameter there exists a minimum perturbation order at which the perturbation series become convergent. It is also found for the open-shell systems that the magnitude of the corresponding Feenberg parameter becomes larger as the spin multiplicity of the system of interest changes from 2 to 4.展开更多
The electron affinities of the isomer XC6H4CH2/ XC6H4CH2- (X=F, Cl, Br) species have been determined using seven density functional theory (DFT) methods. The basis set used in this work is of double-ζ plus polarizati...The electron affinities of the isomer XC6H4CH2/ XC6H4CH2- (X=F, Cl, Br) species have been determined using seven density functional theory (DFT) methods. The basis set used in this work is of double-ζ plus polarization quality with additional diffuse s- and p-type functions, denoted DZP++. Three different types of the neutral-anion energy separations reported in this work are the adiabatic electron affinity (EAad), the vertical electron affinity (EAvert), and the vertical detachment energy (VDE). The most reliable adiabatic electron affinities are obtained at the DZP++ BPW91, BP86, and B3LYP level of theory. The BPW91 methods are the closest to the experiment values; The BHLYP method predicts the smallest EAad and B3P86 method predicts the largest EAad, which are the worst reliable methods. In addition, for a given halogen substituent, the meta isomer has the largest electron affinity and the para isomer has the smallest.展开更多
Objective To identify the diffusion alterations of deep gray matter(GM)and white matter(WM)among Alzheimer’s disease(AD),mild cognitive impairment(MCI)and healthy people by atlas-based analysis(ABA),and to investigat...Objective To identify the diffusion alterations of deep gray matter(GM)and white matter(WM)among Alzheimer’s disease(AD),mild cognitive impairment(MCI)and healthy people by atlas-based analysis(ABA),and to investigate the respective relationship with cognitive function.Methods Twenty-one AD patients(AD group),8 MCI patients(MCI group)and展开更多
Twelve volunteers with normal hearing (9 males and 3 females) participated in this work The sound transfer functions (STFS) from diffuse sound field to the subject's eardrums were measured and correlated...Twelve volunteers with normal hearing (9 males and 3 females) participated in this work The sound transfer functions (STFS) from diffuse sound field to the subject's eardrums were measured and correlated to the temporary threshold shift (TTS) due to fiffuse-exposure.A probe tube with a miniature microphone was used for STF measurements in which successive 1/3 oct bandwidth random noise with central frequency from 0.25 kKz to 8 kHz were used. The subjects were divided into two groups, with the STF maxima at 2 kHz and 4 kHz respectively Pre- and post- exposure sweep Bekesy audiograms were recorded and the temporary thresh old shift calctilated as the difference between the two. Frequency of the maximum TTS was correlated to that of the maximum STF. The average TTS was very small or zero at frequen cies below the band noise exposure , but was noticeable even at the highest measured frequency (8 kHz) for beyond the noise band. Also individual differences in STF were found at frequencies between 2 kHz and 4 kHz展开更多
Searching for effective biomarkers is one of the most challenging tasks in the research ?eld of Autism Spectrum Disorder(ASD). Magnetic resonance imaging(MRI) provides a non-invasive and powerful tool for investi...Searching for effective biomarkers is one of the most challenging tasks in the research ?eld of Autism Spectrum Disorder(ASD). Magnetic resonance imaging(MRI) provides a non-invasive and powerful tool for investigating changes in the structure, function, maturation,connectivity, and metabolism of the brain of children with ASD. Here, we review the more recent MRI studies in young children with ASD, aiming to provide candidate biomarkers for the diagnosis of childhood ASD. The review covers structural imaging methods, diffusion tensor imaging, resting-state functional MRI, and magnetic resonance spectroscopy. Future advances in neuroimaging techniques, as well as cross-disciplinary studies and largescale collaborations will be needed for an integrated approach linking neuroimaging, genetics, and phenotypic data to allow the discovery of new, effective biomarkers.展开更多
Impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment(a MCI) to Alzheimer's disease(AD). As a part of the medial temporal lobe memory sy...Impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment(a MCI) to Alzheimer's disease(AD). As a part of the medial temporal lobe memory system,the hippocampus is one of the brain regions affected earliest by AD neuropathology,and shows progressive degeneration as a MCI progresses to AD. Currently,no validated biomarkers can precisely predict the conversion from a MCI to AD. Therefore,there is a great need of sensitive tools for the early detection of AD progression. In this review,we summarize the specifi c structural and functional changes in the hippocampus from recent a MCI studies using neurophysiological and neuroimaging data. We suggest that a combination of advanced multi-modal neuroimaging measures in discovering biomarkers will provide more precise and sensitive measures of hippocampal changes than using only one of them. These will potentially affect early diagnosis and disease-modifying treatments. We propose a new sequential and progressive framework in which the impairment spreads from the integrity of fibers to volume and then to function in hippocampal subregions. Meanwhile,this is likely to be accompanied by progressive impairment of behavioral and neuropsychological performance in the progression of a MCI to AD.展开更多
基金Supported by the Research Project of Dongguan Higher Education (200910815252)the Beijing Natural Science Foundation(7102102)the Scientific Research Key Program of Beijing Municipal Commission of Ed-ucation(KZ200810025011)~~
文摘To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, a modified algorithm is proposed for calculating these parameters. Magnetic resonance (MR) diffusion tensor images of five healthy volunteers are collected. The diffusion sensitive gradient magnetic fields are applied along 25 directions and the diffusion weighting value is 1 000 s/mm^2. Many positive-indefinite diffusion tensors can be found in the white matter area, such as the genu and the splenium of corpus callosum. Due to the positive-indefinite matrix, the mean diffusivity (MD) and the fractional anisotropy (FA) are under-estimated and over-estimated by using the conventional algorithm. Thus, the conventional algorithm is modified by using the absolute values of all eigenvalues. Results show that both the robustness and the reliability for deriving these parameters are improved by the modified algorithm.
基金Supported by the Foundation for subjects development of Harbin University(No.HXK200716)
文摘This paper investigates the existence of periodic solutions of a three-species food-chain diffusive system with Beddington-DeAngelis functional responses and time delays in a two-patch environment on time scales. By using a continuation theorem based on coincidence degree theory, we obtain sufficient criteria for the existence of periodic solutions for the system. Moreover, when the time scale T is chosen as R or Z, the existence of the periodic solutions of the corresponding continuous and discrete models follows. Therefore, the method is unified to provide the existence of the desired solutions for continuous differential equations and discrete difference equations.
基金project supported by the National High-Technology Research and Development Program of China(Grant No.8632005AA642010)
文摘A new algorithm is presented by using the ant colony algorithm based on genetic method (ACG) to solve the continuous optimization problem. Each component has a seed set. The seed in the set has the value of component, trail information and fitness. The ant chooses a seed from the seed set with the possibility determined by trail information and fitness of the seed. The genetic method is used to form new solutions from the solutions got by the ants. Best solutions are selected to update the seeds in the sets and trail information of the seeds. In updating the trail information, a diffusion function is used to achieve the diffuseness of trail information. The new algorithm is tested with 8 different benchmark functions.
基金Supported by Natural Science Foundation of China(61163047)Natural Science Foundation of Jiangxi Province(20114BAB201036)
文摘When DR (Digital Radiography) images are filtered, it is necessary to preserve the edges and key details. But the existing methods may inevitably take fine details mistaken for noise to remove. In order to solve the problem an improved anisotropic diffu- sion filtering model is proposed. Firstly, a novel diffusion function is introduced based on Perona and Malik model, which well overcomes the high rate of convergence. Secondly, the gradient threshold is modified to an adaptive estimation function, so it is bet- ter at adaptive threshold regulations according to the pixels and iteration times. Finally, the edges are extracted from the restored im- ages and the results are evaluated quantificationally. It is shown from the experiments that the proposed method is effective not only in noise reduction but also in details preserved.
基金Supported by National Science Foundation of China(60403036)National Science Foundation of Shandong Province(Y2003G01)
文摘In this paper, we present a new scheme to segment a given image. This scheme utilizes neuro-fuzzy system to derive a proper set of contour pixels based on multi-scale images. We use these fuzzy derivatives to develop a new curve evolution model. The model automatically detect smooth boundaries, scaling the energy term, and change of topology according to the extracted con- tour pixels set. We present the numerical implementation and the experimental results based on the semi-implicit method. Experi- mental results show that one can obtains a high clualitv edge contour.
文摘Fractional calculus and special functions have contributed a lot to mathematical physics and its various branches. The great use of mathematical physics in distinguished astrophysical problems has attracted astronomers and physicists to pay more attention to available mathematical tools that can be widely used in solving several problems of astrophysics/physics. In view of the great importance and usefulness of kinetic equations in certain astrophysical problems, the authors derive a generalized fractional kinetic equation involving the Lorenzo-Hartley function, a generalized function for fractional calculus. The fractional kinetic equation discussed here can be used to investigate a wide class of known (and possibly also new) fractional kinetic equations, hitherto scattered in the literature. A compact and easily computable solution is established in terms of the Lorenzo-Hartley function. Special cases, involving the generalized Mittag-Leffler function and the R-function, are considered. The obtained results imply the known results more precisely.
基金the National Natural Science Foundation of China (No.21473008 and No.21873011).
文摘Divergences of the single reference perturbation theories due to the addition of diffusion basis functions have been investigated for both closed-shell and open-shell molecular systems. It is found that the oscillatory range of perturbation energies of open-shell systems increases as the spin multiplicity of systems changes from 2 to 4. Feenberg transformation is exploited to treat the divergence problems. It is found numerically that within the interval of Feenberg parameter there exists a minimum perturbation order at which the perturbation series become convergent. It is also found for the open-shell systems that the magnitude of the corresponding Feenberg parameter becomes larger as the spin multiplicity of the system of interest changes from 2 to 4.
文摘The electron affinities of the isomer XC6H4CH2/ XC6H4CH2- (X=F, Cl, Br) species have been determined using seven density functional theory (DFT) methods. The basis set used in this work is of double-ζ plus polarization quality with additional diffuse s- and p-type functions, denoted DZP++. Three different types of the neutral-anion energy separations reported in this work are the adiabatic electron affinity (EAad), the vertical electron affinity (EAvert), and the vertical detachment energy (VDE). The most reliable adiabatic electron affinities are obtained at the DZP++ BPW91, BP86, and B3LYP level of theory. The BPW91 methods are the closest to the experiment values; The BHLYP method predicts the smallest EAad and B3P86 method predicts the largest EAad, which are the worst reliable methods. In addition, for a given halogen substituent, the meta isomer has the largest electron affinity and the para isomer has the smallest.
文摘Objective To identify the diffusion alterations of deep gray matter(GM)and white matter(WM)among Alzheimer’s disease(AD),mild cognitive impairment(MCI)and healthy people by atlas-based analysis(ABA),and to investigate the respective relationship with cognitive function.Methods Twenty-one AD patients(AD group),8 MCI patients(MCI group)and
文摘Twelve volunteers with normal hearing (9 males and 3 females) participated in this work The sound transfer functions (STFS) from diffuse sound field to the subject's eardrums were measured and correlated to the temporary threshold shift (TTS) due to fiffuse-exposure.A probe tube with a miniature microphone was used for STF measurements in which successive 1/3 oct bandwidth random noise with central frequency from 0.25 kKz to 8 kHz were used. The subjects were divided into two groups, with the STF maxima at 2 kHz and 4 kHz respectively Pre- and post- exposure sweep Bekesy audiograms were recorded and the temporary thresh old shift calctilated as the difference between the two. Frequency of the maximum TTS was correlated to that of the maximum STF. The average TTS was very small or zero at frequen cies below the band noise exposure , but was noticeable even at the highest measured frequency (8 kHz) for beyond the noise band. Also individual differences in STF were found at frequencies between 2 kHz and 4 kHz
文摘Searching for effective biomarkers is one of the most challenging tasks in the research ?eld of Autism Spectrum Disorder(ASD). Magnetic resonance imaging(MRI) provides a non-invasive and powerful tool for investigating changes in the structure, function, maturation,connectivity, and metabolism of the brain of children with ASD. Here, we review the more recent MRI studies in young children with ASD, aiming to provide candidate biomarkers for the diagnosis of childhood ASD. The review covers structural imaging methods, diffusion tensor imaging, resting-state functional MRI, and magnetic resonance spectroscopy. Future advances in neuroimaging techniques, as well as cross-disciplinary studies and largescale collaborations will be needed for an integrated approach linking neuroimaging, genetics, and phenotypic data to allow the discovery of new, effective biomarkers.
基金supported by the National Natural Science Foundation of China (91332000,81171021,and 91132727)the Key Program for Clinical Medicine and Science and Technology,Jiangsu Provence,China ( BL2013025 and BL2014077)
文摘Impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment(a MCI) to Alzheimer's disease(AD). As a part of the medial temporal lobe memory system,the hippocampus is one of the brain regions affected earliest by AD neuropathology,and shows progressive degeneration as a MCI progresses to AD. Currently,no validated biomarkers can precisely predict the conversion from a MCI to AD. Therefore,there is a great need of sensitive tools for the early detection of AD progression. In this review,we summarize the specifi c structural and functional changes in the hippocampus from recent a MCI studies using neurophysiological and neuroimaging data. We suggest that a combination of advanced multi-modal neuroimaging measures in discovering biomarkers will provide more precise and sensitive measures of hippocampal changes than using only one of them. These will potentially affect early diagnosis and disease-modifying treatments. We propose a new sequential and progressive framework in which the impairment spreads from the integrity of fibers to volume and then to function in hippocampal subregions. Meanwhile,this is likely to be accompanied by progressive impairment of behavioral and neuropsychological performance in the progression of a MCI to AD.