STUDY ON ACUPUNCTURE AND MOXIBUSTION THERAPY FOR FEMALE URETHRAL SYNDROME

Among 180 patients with female urethral syndrome, 128 were treated by acupuncture and moxibustion and 52 by western medicine as controls. The short-term effective rate in the acupuncture and moxibustion group was 90.6% and the long-term effective rate, 80.4%; whereas the short-term effective rate of the control group was 26.9% (P 0.05). Sixty-nine cases from the acupuncture and moxibustion group and 39 from the control group were subjected before and after treatment to determinations of the maximal bladder pressure, maximal abdominal pressure, bladder-neck pressure, and maximal urethral closure pressure during urination. All these indexes were decreased remarkably in the acupuncture and moxibustion group, while no changes were observed in the control group.

43 CASES OF POSTOPERATIVE GASTROINTESTINAL DYSFUNCTION TREATED WITH ACUPUNCTURE PLUS AURICULAR-PLASTER THERAPY

After general surgical operation, a part of patients occur gastrointestinal dysfunction.The author has treated 43 cases of postoperative gastrointestinal dysfunction by acupuncture plus auricularplaster therapy. Body points Neiguan((PC 6 ), Hegu(LI 4 ), Zusanli (ST 36 ) and Gongsun(SP4), and auricular points Shenmen(MA-TF 1 ), Wei, Jiaogan(MA-AH 7) and Dachang(MA-SC 4),etc. were selected. Results indicated that 31 cases were cured, 11 cases were effective and one casewas ineffective. The total effective rate was 97. 7%. There was no statistically significant differencebetween the kinds of diseases operated and therapeutic effects. The method is convenient and its actionlasts a long period with more satisfactory effects for treatment of postoperative gastrointestinal dysfunction.

基于数据挖掘的针灸治疗肺系疫病古代文献整理研究

目的收集古文献中针灸治疗肺系疫病的有关条文,分析针灸治疗肺系疫病的应用特点,为现代提供临床借鉴。方法从国家图书馆古籍文献纸质书籍、国家图书馆电子文献数据库电子书籍、上海中医药大学图书馆纸质书籍、电子书籍中收集秦至清末时期内针灸治疗肺系疫病的古籍文献条文,按照纳入标准与排除标准进行筛选,运用IBM SPSS Statistics 27.0进行频数分析、聚类分析、主成分与因子分析及关联规则分析。结果共纳入226条针灸治疗肺系疫病的文献条文,其中来源于《证治准绳》条文最多,为32条,针灸疗法包括12大类,使用频次最高的为刺血56次,针灸治疗涉及68个穴位,使用频次超过5次的穴位有2个,依次为少商、委中。结论在针灸治疗肺系疫病时可采用针刺与刺血等多种方式相结合,可用“间使、肩井、曲池、膏肓”为治疗核心处方,并辅以辨证取穴。

Effect of electroacupuncture and herbal cakepartitioned moxibustion on anxiety and depression in patients with Crohn's disease in remission

Objective： To observe the effect of electroacupuncture （EA） and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn＇s disease （CD） in remission. Methods： Sixty CD cases were randomly allocated into an EA group （n=30） and an herbal cake-partitioned moxibustion group （n=30） using the random number table by the ratio of 1：1. In addition, 30 healthy subjects were included in a control group. Bilateral Tianshu （ST 25）, Qihai （CV 6） and Zhongwan （CV 12） were used in the EA and herbal cake- partitioned moxibustion groups. The treatment was done 3 times a week, for a total of 12 weeks. The efficacy was evaluated using self-rating anxiety scale （SAS）, self-rating depression scale （SDS） and traditional Chinese medicine （TCM） symptom scores. Results： Before treatment, the SAS and SDS scores in CD patients were remarkably higher than those in healthy subjects. After EA or herbal cake-partitioned moxibustion treatment, the SAS and SDS scores were significantly decreased in both groups, showing significant intra-group differences （P〈0.05）; the symptom scores of abdominal pain （severity, frequency and duration）, bowel sounds/flatus and general fatigue were significantly decreased, showing significant intra-group differences （P〈0.05）; however, there were no between-group statistical differences （P〉0.05）. Conclusion： Both EA and herbal cake-partitioned moxibustion can significantly decrease abnormally high SAS and SDS scores in CD patients as well as TCM symptom scores. The two therapies share similar effects in alleviating common symptoms and improving anxiety and depression.

Evaluation of the prevention and treatment effects of acupuncture-moxibustion for Alzheimer disease based on various mouse models

Objective:To evaluate the prevention and treatment effects of acupuncture-moxibustion for Alzheimer disease(AD)based on various AD mouse models.Methods:Several representative types of mouse models were selected according to the pathophysiological causes of AD,including senescence accelerated mouse/prone(SAMP)mice,soluble amyloid-βprotein(Aβ)injection mice/rats,amyloid precursor protein(APP)transgenic mice,and APP/PS1 double transgenic mice.Through the observation of behavioral changes and analysis of core items,the possible mechanisms of acupuncture-moxibustion in preventing and treating AD were explored.Results:Acupuncture-moxibusiton therapy can improve AD mice's cognitive dysfunction;the major action mechanisms including increasing cerebral blood flow,improving the expressions of vital proteins in the hippocampus,preventing neuron cell apoptosis,promoting the clearance of Aβdeposition,activating autophagy pathway to reduce memory deficits and regulating the metabolisms of brain-derived neurotrophic factor,tyrosine kinase receptor B,N-acetylaspartate and glutamic acid.Conclusion:Although the optimal mouse model is not determined,it is sure that acupuncture-moxibustion therapy can improve cognitive function.A more suitable AD animal model should be duplicated in order to better explore the inherent action mechanism of acupuncture-moxibustion in preventing and treating AD.

针灸干预机体亚健康症状的运用与思考

当前机体亚健康者在人群中占比较高,亚健康向健康的转归主要取决于自身免疫水平和适时有效的干预措施。中医学素有治未病的理念,可指导针灸临床干预机体亚健康症状而预防疾病。从针灸干预机体亚健康症状的理论基础、临床运用和调节机制三个方面进行探讨,认为针灸可明显改善机体亚健康症状,并能通过调理偏颇体质纠偏却病。针灸调节作用具有整体性、双向性特点,针灸通过调节神经-内分泌-免疫网络,维持机体内环境稳态,刺灸信号从外周传入中枢进行整合,不会产生毒副作用。针灸作为传统中医学独具一格的非药物疗法,应在亚健康领域充分开发,未病先防,欲病救萌,防微杜渐,满足患者对健康的期待,并用现代科学方法研究其作用机制。

针刺与隔药灸经筋结点法治疗脑卒中后上肢痉挛性瘫痪临床观察

目的探讨针刺与隔药灸经筋结点法治疗脑卒中后上肢痉挛性瘫痪效果。方法选取2020年1月—2021年6月兴国县中医院收治的62例脑卒中后上肢痉挛性瘫痪患者为研究对象,其中2020年1月—2020年9月收治的患者为参照组(31例),实施传统针刺治疗;2020年10月—2021年6月收治的患者为研究组(31例),在对照组的基础上加用隔药灸经筋结点法治疗。对比两组中医证候积分、肌张力、上肢运动功能及日常生活能力。结果治疗后,两组中医证候积分均降低,且研究组低于参照组(P<0.05);两组肌张力评分降低,上肢运动功能及日常生活能力评分增加,且研究组肌张力评分低于参照组,上肢运动功能及日常生活能力评分高于参照组(P<0.05)。结论对脑卒中后上肢痉挛性瘫痪患者积极实施针刺与隔药灸经筋结点法治疗,效果确切,能明显改善临床症状、抑制肌张力增高、恢复上肢运动功能、提升日常生活能力。

针灸联合补中益气汤治疗产后尿潴留临床观察

目的探究针灸联合补中益气汤治疗产后尿潴留的临床效果。方法从南昌市第一医院选取2020年6月—2022年6月收治的70例产后尿潴留患者为研究对象展开分组研究,按随机数字表法分为对照组和观察组,每组35例。对照组采用常规西医治疗,观察组在对照组的基础上接受针灸配合补中益气汤治疗。比较两组临床疗效,排尿相关指标(首次排尿时间、首次排尿量、膀胱残余尿量),治疗前后疼痛视觉模拟量表(VAS)评分、小便顺畅程度评分、腹部症状评分。结果观察组临床治疗总有效率88.57%(31/35)高于对照组的62.86%(22/35)(P<0.05)。观察组首次排尿时间短于对照组,观察组首次排尿量大于对照组,观察组膀胱残余尿量少于对照组(P<0.05)。观察组治疗后VAS评分、小便顺畅程度评分、腹部症状评分均低于治疗前,同时低于对照组(P<0.05)。结论对产后尿潴留患者采用针灸配合补中益气汤可以有效改善排尿情况,提升小便顺畅程度,缓解疼痛及腹部症状,提高治疗效果。

Therapeutic observation of acupuncture plus heat-sensitive moxibustion for chronic pelvic inflammatory disease

Objective：To observe the therapeutic efficacy of acupuncture plus heat-sensitive moxibustion in treating chronic pelvic inflammatory disease （CPID）, for selecting an effective acupuncture-moxibustion method in treating chronic pelvic inflammation. Methods：Eighty CPID subjects were enrolled and divided into two groups by randomized single-blind method, 40 in each group. The observation group was intervened by acupuncture plus heat-sensitive moxibustion, while the control group was by acupuncture plus box-moxibustion, once every other day, 10 sessions as a treatment course, but the period time was skipped. The therapeutic efficacy was observed after 3 treatment courses. Results：The recovery rate was 45.0% and the total effective rate was 95.0% in the observation group, versus 20.0% and 80.0% in the control roup. There were significant differences in comparing the recovery rate and the total effective rate between the two groups （P〈0.05）. Conclusion：Acupuncture plus heat-sensitive moxibustion can produce a higher therapeutic efficacy in treating CPID than acupuncture plus box-moxibustion, and this is an easy-to-operate and safe method without adverse effect.

Clinical Observation of Acupuncture-moxibustion for Alzheimer’s Disease

Objective: To observe the clinical efficacy of acupuncture-moxibustion in treating Alzheimer's disease(AD). Methods: Forty-eight eligible AD patients were enrolled to receive acupuncture plus herb-partitioned moxibustion. Mini-mental state examination(MMSE) was adopted for evaluation before and after intervention, and the therapeutic efficacy was observed. Results: After intervention, the MMSE score changed significantly(P<0.01), and the total effective rate was 83.3%. Conclusion: Acupuncture-moxibustion can significantly improve the cognitive function of AD patients, beneficial to the general promotion of the quality of life.

Analysis of clinical application patterns in acupuncture-moxibustion treatment of Alzheimer disease

Objective:To summarize the clinical application patterns in acupuncture-moxibustion treatment of AD by reviewing the clinical literatures on acupuncture-moxibustion for Alzheimer disease(AD)published between January 2009 and December 2019.Methods:China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-text Database(Wanfang),Chongqing VIP Database(CQVIP),Chinese Medicine Acupuncture-moxibustion Information Database,PubMed Medical Data Retrieval Service System,Springer Database and Ovid Technologies(OVID)were retrieved to screen clinical studies of acupuncture-moxibustion treatment of AD according to the inclusion and exclusion criteria to conduct quantitative,clustering and association analyses.Results:In acupuncture-moxibustion treatment of AD,the frequently used points were Baihui(GV 20),Zusanli(ST 36),Sishencong(EX-HN 1),Taixi(KI 3),Sanyinjiao(SP 6),and Neiguan(PC 6)in the descending order.Regarding meridians,the most frequently used one was the Governor Vessel,followed by the Stomach Meridian of Foot Yangming and Gallbladder Meridian of Foot Shaoyang.From the perspective of body regions,the points in the head-face region and the lower-limb region had the highest frequencies,followed by the upper-limb,back and chest-abdomen regions.The point group,Baihui(GV 20)and Sishencong(EX-HN 1)-Neiguan(PC 6)-Sanyinjiao(SP 6),showed the most significant association,and the group winning the second place was Baihui(GV 20)and Sishencong(EX-HN 1)-Neiguan(PC 6)-Zusanli(ST 36).The clustering analysis showed that the commonly used point pairs included Zusanli(ST 36)-Sishencong(EX-HN 1)and Taixi(KI 3)-Sanyinjiao(SP 6),which were closely associated with Baihui(GV 20).By analyzing the three commonly used acupuncture-moxibustion methods,acupuncture plus medication was found achieving the best result in the total effective rate and mini-mental state examination(MMSE)score,followed by monotherapy of electroacupuncture therapy,and these two methods were superior to acupuncture alone(P<0.05);the scores of MMSE,Alzheimer disease assessment scale-cognitive section(ADAS-cog)and activity of daily living scale(ADL)showed significant improvements after treatment(all P<0.01).Conclusion:In the acupuncture-moxibustion prescriptions for AD,the main points are Baihui(GV 20),Sishencong(EX-HN 1),Neiguan(PC 6),Zusanli(ST 36),Sanyinjiao(SP 6)and Taixi(KI 3).Monotherapy of acupuncture has the highest frequency amongst the treatment methods,but its effective rate is lower than that of acupuncture plus medication and monotherapy of electroacupuncture.

开四关联合长蛇灸治疗慢性阻塞性肺疾病稳定期临床观察

目的探索针刺四关穴联合长蛇灸治疗肺脾肾气虚型慢性阻塞性肺疾病(COPD)稳定期患者的临床效果。方法选取2020年10月—2022年1月于南昌市洪都中医院就诊的60例肺脾肾气虚型COPD稳定期患者作为研究对象,用抽签法,按1∶1分成对照组(氧疗、沙美特罗替卡松粉吸入剂)、试验组(氧疗、沙美特罗替卡松粉吸入剂加针刺四关穴联合长蛇灸疗法),各30例进行治疗,6个月后对比2组患者的肺功能关键指标、中医症状积分以及总体效果。结果试验组在提高肺功能、改善中医症状上明显优于对照组,差异有统计学意义(P<0.05)。试验组总有效率为90.00%(27/30),高于对照组的73.33%(22/30),差异有统计学意义(P<0.05)。结论应用开四关结合长蛇灸能增强肺脾肾气虚型COPD稳定期患者的肺功能,缓解临床症状,疗法简便、安全、有效。

运用“调神针法”治疗心身疾病的临床经验

该文总结庄礼兴教授运用“调神针法”治疗心身疾病的诊疗思路及操作要点。庄礼兴认为心身疾病可细分为“心身疾病”和“身心疾病”,前者以调节脑神为主,主穴取四神针、神庭、印堂、神门、三阴交,随症佐以素髎、水沟、申脉、照海、合谷、太冲等;后者以改善原发病为主,辅以调神(头部督脉排刺)。穴位组方从脑神立论,尤重督脉,同时强调调理脏腑,疏通气血。针刺得气后施以导气同精法,并配合耳穴贴压或火针患处以增强疗效。

基于近15年国内期刊文献的针灸病谱变化规律研究

目的:分析近15年针灸临床文献,总结针灸病谱,分析病谱变化及其原因。方法:检索2006-2020年,中国生物医学文献数据库、中国期刊全文数据库(CNKI)、万方数据库(WANFANG)和维普数据库(VIP)中的针灸文献,进行整理分析,总结针灸病谱。比较1978-2005年与2006-2020年文献,分析病谱变化情况及变化原因。结果:共纳入符合标准文献78474篇,包括564种病症,其中,疾病系统文献篇数前5位依次为肌肉骨骼系统和结缔组织疾病、神经系统、精神和行为障碍、泌尿生殖系统、消化系统;具体病症文献前10位依次为脑血管病及后遗症、颈椎病、腰椎间盘突出症、面神经麻痹、膝关节骨性关节炎、睡眠障碍、偏瘫、肩关节周围炎、抑郁症、糖尿病及并发症。结论:针灸疗法临床应用广泛,且适应证不断扩大。与1978-2005年病谱比较,病谱发生较大变化,删减62种病症,新增173种病症。病谱变化原因与针灸疗法的发展、发病率的变化、人们需求的提升、医学技术的进步等因素相关。

中医药在高血压前期防治中的应用综述

中医药运用治未病理论,从整体出发,辨证运用中药方剂及非药物疗法,联合生活方式干预,降低血压,改善体质,保护靶器官,阻断高血压进程,具有综合调节的独特优势。但目前的研究尚存在一些问题:①缺乏客观的病机演变理论;②证候分型标准多依据个人临床经验制定,缺乏规范化的诊断标准;③随机对照试验较少,样本量小,观察周期短,循证医学证据不足。未来可进行以下研究:①建立数字化平台,整理挖掘古今文献,完善、总结高血压前期病因病机演变理论、中医证候分布特点;②增加专家的咨询调查和流行病学研究,建立规范的中医证型诊断标准,统计分析西医检查指标与中医证候的相关性,为临床辨证提供客观依据。③开展大样本、多中心、随机、双盲、对照试验,为中医药在高血压前期防治中的应用提供循证医学支持。

帕金森病伴发便秘的病因病机及针灸治疗研究进展

帕金森病(Parkinson’s disease,PD)除了典型的运动症状如运动迟缓、肌强直、静止性震颤外,常伴随非运动症状的发生。便秘为最常见的非运动症状之一,严重影响患者的生活质量,而且与帕金森病相关药物使用剂量之间相互影响。针对便秘的西医治疗未得到充分重视,且长期应用刺激性泻药,不良反应大、易形成药物依赖;而针灸在治疗帕金森病伴便秘方面有独特优势。此文查阅近10年来国内外相关文献研究资料,对帕金森病的病因病机及针灸治疗研究进展进行归纳论述,以期为临床治疗帕金森病伴发便秘提供参考。

除痹汤熏洗联合针灸对颈肩腰腿痛患者关节功能及生活质量的影响

目的探讨针灸联合除痹汤熏洗对颈肩腰腿痛患者关节功能及生活质量的影响。方法选取2019年2月—2021年2月定南第二医院收治的颈肩腰腿痛患者70例,依据治疗方法分为除痹汤熏洗联合针灸治疗组(联合治疗组)、单独针灸治疗组(单独治疗组),各35例,统计分析2组患者的疼痛程度、运动功能、关节功能、日常生活能力、临床疗效、生活质量。结果治疗后,联合治疗组患者的视觉模拟量表(VAS)评分低于单独治疗组(P<0.05),Fugl-Meyer运动功能活动量表(FMA)评分、日本骨科协会关节功能评定量表(JOA)评分、Barthel指数(BI)评分均高于单独治疗组(P<0.05)。联合治疗组的总有效率为97.14%(34/35)高于单独治疗组的80.00%(28/35)(P<0.05),联合治疗组患者的疼痛、睡眠、精力、躯体活动、情感反应、社会孤独感评分及诺丁汉健康量表(NHP)总分均低于单独治疗组(P<0.05)。结论针灸联合除痹汤熏洗治疗较针灸单独治疗更能有效改善颈肩腰腿痛患者关节功能及生活质量。

Reflection and prospect on acupuncture-moxibustion in treating Hashimoto's thyroiditis

Objective： To categorize and summarize the clinical and mechanism studies of the past 30 years on the treatment of Hashimoto＇s thyroiditis（HT） with moxibustion, moxibustion plus medication, and acupuncture plus medication, etc., and to analyze the current problems. Methods： The clinical and laboratory studies related to the treatment of HT with acupuncture-moxibustion therapies published before June 2015 were retrieved from MEDLINE, Excerpta Medica Database（EMBASE）, China National Knowledge Infrastructure（CNKI）, Wanfang Academic Journal Full-text Database（Wanfang） and Chongqing VIP Database（CQVIP）. Results： Moxibustion, moxibustion plus medication, and acupuncture plus medication can produce certain therapeutic effects in treating HT. Conclusion： The research on the treatment of HT with acupuncture-moxibustion therapies is rather limited in the amount and content. In the future, standardization should be fortified, specific moxibustion research needs deepening, and the action mechanism of moxibustion should be emphasized.

Thinking on Functional Mechanism of Acupuncture for Inflammatory Bowel Diseases Based on Metabolomics

Acupuncture has a good therapeutic effect in treatment of inflammatory bowel diseases(IBD), but its functional mechanism has not been systematically explained. Metabolomics is the scientific study of dynamic chemical processes involving metabolites as well as metabolic response of living organisms. Metabolomics, a research method with integrity and dynamics, corresponds to the overall regulatory effect of acupuncture and is in line with the overall concept of traditional Chinese medicine(TCM) and the concept of homeostasis. In the recent years, metabolomics has been extensively applied to the clinical and experimental study of IBD, and its potential applied value has been unanimously acknowledged by the researchers. In this article, the application status of metabolomics in acupuncture is summarized, and the research ideas to study the mechanism of acupuncture in the regulation and control of IBD by metabolomics are preliminarily explored.

浮针扫散法对腰背肌筋膜疼痛综合征临床疗效的影响研究

目的:研究浮针扫散法联合红外光治疗仪治疗腰背肌筋膜疼痛综合征(MPS)的有效性及安全性。方法:选取72例腰背MPS患者作为研究对象,采用随机数字表法分为治疗组(36例)与对照组(36例)。治疗组给予浮针扫散法联合红外光治疗仪治疗,对照组给予传统中医针刺联合红外光治疗仪治疗,7 d为1个疗程,共治疗2个疗程。于治疗前、治疗1个疗程后、治疗2个疗程后进行麦吉尔(McGill)疼痛问卷简表(SF-MPQ)评分、Roland-Morris功能障碍调查表(RMDQ)评分。结果:治疗后,治疗组有效率为87.9%,高于对照组70.6%(P<0.05)。治疗后,不同时间段2组疼痛评级指数总分(PRI)、视觉模拟定级(VAS)、现有疼痛强度(PPI)评分、RMDQ评分均较治疗前降低(P<0.05),且治疗组上述指标均低于对照组(P<0.05),均有统计学意义。结论:浮针扫散法联合红外光治疗仪疗法能够有效地治疗腰背MPS,改善患者腰部功能,减轻疼痛。