Clinical Analysis of Dispelling Wind,Eliminating Lung and Relieving Cough Combined with Western Medicine in the Treatment of Cough Variant Asthma in Children

Objective:This study mainly explores the clinical effect of dispelling wind,eliminating lung and relieving cough combined with western medicine in the treatment of cough variant asthma.Methods:80 children with cough variant asthma accepted by our hospital from January 2018 to December 2020 were randomly selected for the study and divided into two groups.One group was the reference group(40 cases)treated with procaterol hydrochloride tablets and montelukast sodium,and the other group was the research group(40 cases)・The method of eliminating wind,eliminating lung and relieving cough was combined with procaterol hydrochloride tablets and montelukast sodium to observe and compare the curative effects of the two groups.Results:There was no significant difference in TCM symptom score and eosinophil(EOS)count between the two groups before treatment(P>0.05);After treatment,the TCM symptom scores of coughs,pharyngeal itching,expectoration,nasal congestion and nasal itching in the research group were lower than those in the reference group,and the EOS count was lower than that in the reference group(P<0.05);The effective rate of research group was higher than that of reference group(P<0.05).Conclusions:For children with cough variant asthma,Qufeng Sufei cough relieving method combined with procaterol hydrochloride and montelukast sodium can improve children's symptoms and reduce eosinophil count.

MOSCOW VS.NATO:COMPROMISE WILL NOT DISPEL APPREHENSIONS

After six rounds of tough bargaining,Russia and the North Atlantic Treaty Or-ganization reached on May 14 an agreement,officially known as a“FoundingAct on Mutual Relations.Co-operation and Scurity between NATO and the RUS-sian Federation".The document was formally signed by Russian President BorisYeltsin on May 27 in Paris together with the leaders of the 16 NATO memberstates.The event signifies a temporary compromise between the two sides over theNATO’s eastward expansion.Soon after the accord was reached.

A Study of Dispelling Lexical Fossilization for English Learners

Fossilization was first proposed by the famous British linguist Larry Selinker in his article Interlanguage in 1972.NonEnglish majors make many lexical errors in the process of English writings in universities.Therefore,their writing levels may reach a plateau and fail to make progress.Once English vocabulary is fossilized,it will prevent the development of students' writing competence.Inspired and stimulated by the observation of lexical errors in the university,the author intends to explore effective and feasible methods of dispelling lexical fossilization from the perspective of the theories of prototype and basic-level category and tries to provide a useful supplement in this area.

A Cognitive Study Based on Iconicity of Dispelling Lexical Fossilization of Chinese College Students

Fossilization is complex,repeated and durative,it appears in various aspects of Interlanguage like phonetics,syntax and semantics.College English vocabulary learning stage is an obvious period of lexical fossilization.This paper mainly uses qualitative research method to analyze dispelling lexical fossilization of Chinese college students based on iconicity of Langacker’s grammar,with the purpose of improving the“quantity”and“quality”of English vocabulary of Chinese college students and offering some pedagogical proposals to improve English vocabulary teaching effect of college students.

Explore the direct and/or the synergistic antihypertensive effects of wind-dispelling herbs involving Fangfeng and Baizhi on hypertensive rats with liver-yang hyperactivity based on vasoactive substances

Objective： To explore the direct and/or the enhancing antihypertensive effects of wind-dispelling herbs involvingFangfeng （Saposhnikoviae Radix） and Baizhi （Angelicae dahuricae Radix） using liver-yang hyperactivity renalhypertension rat. Methods： Model rats with hyperactivity of liver-yang hyperactivity were prepared using male SD rats.Once successful, the rats were randomly divided into groups and given medicine by gavage for 4 weeks. Blood wascollected from the abdominal aorta to prepare serum. Serum nitric oxide （NO） concentration was determined bychemical colorimetry. The contents of ET, TXB2 and 6-K-PGF1a were determined by enzyme linked immunosorbentassay （ELISA）. Results： Compared with the control model group, the blood pressure, serum ET and TXB2 of rats in thewind dispelling medicine group was not significantly reduced, while those of rats in captopril group, Tianma GoutengDecoction I group （TGD group） decreased significantly （P 〈0.05 for both）. Interestingly, the blood pressure, serum ETand TXB2 of rats in the combination group （wind dispelling medicine ＆ TGD） decreased significantly compared withboth wind dispelling medicine group and TGD group. Meanwhile, the levels of serum NO and 6- K-PGF1a in thecombination group was much higher than those in the wind dispelling medicine group or TGD group （P 〈0.05 for both）.However, the levels of serum NO and 6- K-PGF1a in the wind dispelling medicine group was not significantly increasedcompared with the model group. Conclusion： There is no direct pressure lowering effects of wind dispelling medicinealone, while wind dispelling medicine could potentiates the antihypertensive effects of Tianma Gouteng Decoction I.Besides, the synergistic effects may be related to decreased ET and TXB2 levels and the increased NO and 6- K-PGF1alevels.

王麟鹏教授“逐邪通络”法治疗原发性三叉神经痛

总结王麟鹏教授运用“逐邪通络”法治疗原发性三叉神经痛的学术思想。王麟鹏教授通过总结前人经验,提出“逐邪通络”针刺法,分期治疗原发性三叉神经痛;强调应根据邪气的致病特点、发作分期、正邪盛衰确定不同的针刺方案,提出局部取穴应用经络辨证为主;主张疼痛发作期以祛邪为要,缓解期主张扶正与祛邪兼而有之,重视调理脏腑、疏通经络,慎用扳机点的治疗理念,获得很好的临床效果。

通络平喘方治疗儿童咳嗽变异性哮喘的临床应用研究

[目的]观察通络平喘方治疗咳嗽变异性哮喘(cough variant asthma,CVA)的疗效及作用机制。[方法]将72例CVA患儿随机分为2组,试验组和对照组各36例。试验组予通络平喘方口服,对照组予氨溴特罗+孟鲁司特钠口服,均治疗2周,比较患者用药前后症状积分、外周血嗜酸性粒细胞(eosinophils,EOS)、血清总免疫球蛋白E(immunoglobulin E,IgE)、白细胞介素-4(interleukin-4,IL-4)、干扰素-γ(interferon-γ,IFN-γ)的变化。[结果]用药后两组患儿的症状积分较前均有改善(P<0.01),试验组明显优于对照组(P<0.01,P<0.05);试验组总有效率为94.44%,明显优于对照组80.56%(P<0.05);试验组的起效时间明显短于对照组(P<0.05)。与本组用药前比较,两组患儿EOS、IgE、IL-4水平均有所降低(P<0.01);IFN-γ水平有所升高(P<0.01),两组间比较差异无统计学意义(P>0.05)。随访3个月,试验组复发率为15%,对照组复发率为33%,差异有统计学意义(P<0.01)。[结论]通络平喘方可有效治疗CVA,可明显改善患儿的咳嗽及相关症状,降低CVA的复发率,作用机制与降低炎症因子水平有关。

益气活血祛痰方治疗支气管哮喘合并阻塞性睡眠呼吸暂停低通气综合征气虚痰瘀证的研究

目的评价益气活血祛痰方联合西医治疗慢性持续期支气管哮喘合并阻塞性睡眠呼吸暂停低通气综合征气虚痰瘀证患者的临床疗效。方法选择2016年1月—2021年6月于泰州市第四人民医院就诊的80例慢性持续期支气管哮喘合并阻塞性睡眠呼吸暂停低通气综合征气虚痰瘀证患者,根据随机数字表分成对照组及观察组各40例,对照组给予常规治疗及持续气道正压通气,观察组在对照组治疗基础上给予益气活血祛痰方水煎液口服,2组均持续干预3个月。观察2组患者治疗前后中医证候积分(包括气喘、咳嗽、咳痰、打鼾、憋醒、日间嗜睡、倦怠乏力)、哮喘控制测试问卷(ACT)评分、圣乔治呼吸问卷(SGRQ)评分、Epworth嗜睡量表(ESS)评分、匹兹堡睡眠指数(PSQI)评分、肺功能指标[呼气峰值流速(PEF)、第一秒用力呼气容积占预计值百分比(FEV_(1)%预计值)、第一秒用力呼气容积与用力肺活量比值(FEV_(1)/FVC)]、多导睡眠图参数[呼吸暂停低通气指数(AHI)、快速眼动睡眠期(REM)、氧减指数(ODI)、动脉血氧饱和度(SaO_(2))、最低SaO_(2)、觉醒指数]、炎症相关指标[血清C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、血管内皮生长因子(VEGF)水平和呼出气一氧化氮(FeNO)水平]变化,统计2组总体治疗效果及不良反应发生情况。结果2组治疗后中医证候积分、SGRQ评分、ESS评分、PSQI评分、AHI、ODI、觉醒指数及血清CRP、IL-6、TNF-α、VEGF水平和FeNO水平均较治疗前明显降低(P均<0.05),且观察组上述各项指标均明显低于对照组(P均<0.05);2组治疗后ACT评分、PEF、FEV_(1)%预计值、FEV_(1)/FVC、REM、SaO_(2)、最低SaO_(2)均较治疗前明显升高(P均<0.05),且观察组上述各项指标均明显高于对照组(P均<0.05)。观察组治疗3个月后的总有效率明显高于对照组[92.5%(37/40)比82.5%(33/40),P<0.05],治疗期间不良反应发生率明显低于对照组[10.0%(4/40)比27.5%(11/40),P<0.05]。结论益气活血祛痰方联合西医治疗支气管哮喘合并阻塞性睡眠呼吸暂停低通气综合征气虚痰瘀证患者的效果优于单纯西医治疗,在减轻患者临床症状,控制哮喘发作,改善肺功能和睡眠质量方面具有明显优势,其作用机制可能与抑制炎症反应相关。

祛风脱敏通窍法治疗小儿过敏性鼻炎的经验介绍

过敏性鼻炎是儿科临床常见病、多发病,近年来发病率呈逐年升高趋势。本文旨在介绍万力生教授辨治小儿过敏性鼻炎的经验,为临床小儿过敏性鼻炎的诊治开拓思路。万力生教授认为“体禀特异,外风引动”为其核心病机,运用祛风脱敏通窍治法,创立验方“祛风脱敏通窍汤”,分期辨治小儿过敏性鼻炎。并附验案1例,以飨同道。

益气养阴散邪法治疗玫瑰痤疮肺胃热盛证的效果 及对面部皮肤状态的影响

目的探讨益气养阴散邪法治疗玫瑰痤疮肺胃热盛证的效果及对面部皮肤状态的影响。方法选取2020年2月至2023年2月收治的80例玫瑰痤疮肺胃热盛证患者为研究对象,按照随机数字表法将其分为对照组与观察组,各40例。对照组采用常规疗法,观察组在对照组基础上加益气养阴散邪法治疗。比较两组的治疗效果。结果观察组的治疗总有效率高于对照组(P<0.05)。治疗后,观察组的白细胞介素-17(IL-17)、白细胞介素-37(IL-37)、核因子-κB(NF-κB)水平低于对照组(P<0.05)。治疗后,观察组的皮肤角质层含水量、表皮皮脂含量高于对照组,经皮水分丢失量低于对照组(P<0.05)。治疗后,观察组的痤疮特异性生活质量问卷(Acne-QOL)各维度评分均高于对照组(P<0.05)。结论益气养阴散邪法治疗玫瑰痤疮肺胃热盛证的效果显著,能够减轻炎性反应,改善面部皮肤状态,提高患者的生活质量。

伏风理论指导儿科过敏性疾病辨证论治

提出特禀质儿童的体质特点是伏风内潜,一旦患儿为外来“虚邪贼风”所引,则发生如鼻鼽、风咳、哮喘、风瘾、湿疹等“风病”(过敏性疾病)。这类风病治疗应当以消风法为主,辨证配用散邪、除湿、润燥、豁痰、凉血、养血、固表等治法治疗。介绍了如何以伏风理论认识小儿鼻鼽、风咳、哮喘、风瘾、湿疹等过敏性疾病的病因病机、临床辨证,以及以消风法为主治疗这些疾病的有效经验方药。

论食品安全权的权利伦理基质及其价值

在当代权利伦理学和人权伦理学的价值谱系中,食品安全权因其与生命权、发展权以及健康权、怯弱权等的密切关系而有其既基础、本源又核心、根本的价值意义。作为一种集法律权利和道德权利于一体的基本人权,食品安全权既是一种源自人最内在、最常见和最基本的人权,也是人之为人最基本的价值诉求和社会所需要的最基本最核心的价值关怀。生而为人必然具有对生命的珍重、对健康的珍惜,此则构成人最为内在亦最为强烈的生命权和健康权,而生命本身和健康的脆弱性又使人产生了与生命权和健康权相契合的怯弱权。生命权、健康权、怯弱权内在地要求食品安全权。尊重和保护公民的食品安全权既是生命权的价值诉求,也是怯弱权和健康权的集中表现。食品安全权因其特有的基础性、本原性权利诉求和价值追求必然成为当代权利伦理学和人权伦理学以及人本主义伦理学、人道主义伦理学和生命伦理学价值大厦的“拱心石”和“顶梁柱”。

Application of buried auricular point combined with Wenjing Sanhan prescription in arteriosclerosis obliterans patients with resting pain

BACKGROUND Research on the combined use of ear acupoint embedding beans and warming meridians with cold-dispersing formulas for alleviating resting pain in patients with arteriosclerosis obliterans(ASO)remains limited.AIM To explore the therapeutic efficacy of auricular point embedding beans combined with Wenjing Sanhan prescription in alleviating resting pain in patients with lower-limb ASO.METHODS A total of 100 patients with ASO experiencing resting pain who were treated at our hospital from January 2022 to January 2023 were enrolled.They were randomly allocated into two groups using a double-blind approach.The control group was treated using a warming meridian with a cold-dispersing formula,while the study group received additional treatment with ear acupoint embedding beans.The clinical efficacy,ankle-brachial artery pressure ratio,hemorheological indicators,and traditional Chinese medicine symptom scores were compared between the two groups.RESULTS The clinical efficacy rate in the study group was significantly higher(94.00%)than that in the control group(72.00%,P<0.05).Moreover,the ankle-brachial artery pressure ratio was significantly higher in the study group after treatment(P<0.05).Hemorheological parameters,including whole blood viscosity,plasma viscosity(1.83±0.11)mPa/s,fibrinogen levels(3.30±0.21)g/L,platelet adhesion rate(49.87%±10.51%),and erythrocyte aggregation index(1.79±0)were improved in the study group compared to the control group.In addition,the scores for decreased skin temperature(1.41±0.26),intermittent claudication(1.30±0.20),and resting pain(1.23±0.31)were significantly lower in the study group than those in the control group(all P<0.05).The level of oxidative stress in the study group also exhibited significant improvement(P<0.05),and the levels of inflammatory factors were considerably lower than those in the control group.CONCLUSION The combination of ear point embedding beans and Wenjing Sanhan prescription demonstrates promising clinical efficacy in alleviating resting pain associated with ASO.

“温阳祛瘀”中药熏洗联合复方益母草胶囊对阳虚血瘀型子宫复旧不全产妇早期康复的临床研究

目的:研究分析“温阳祛瘀”中药熏洗联合复方益母草胶囊对阳虚血瘀型子宫复旧不全产妇早期康复的临床效果。方法:前瞻性纳入2021年4月—2023年4月在广东省人民医院赣州医院妇产科住院的阳虚血瘀型子宫复旧不全产妇80例,将患者按照随机数字表法分为治疗组(n=40)和对照组(n=40)。对照组在常规治疗的基础上加用复方益母草胶囊,治疗组在对照组基础上加以“温阳祛瘀”中药熏洗治疗。比较两组临床症状消失时间、子宫恢复情况、疼痛情况、睡眠质量、心理状态、临床疗效。结果:治疗组恶露、腹痛消失时间均早于对照组,子宫底高度、子宫体积均小于对照组,子宫腔积液量少于对照组,视觉模拟评分法(VAS)、抑郁自评量表(SDS)、焦虑自评量表(SAS)、匹兹堡睡眠质量指数(PSQI)评分均低于对照组,临床疗效优于对照组,差异均有统计学意义(P<0.05)。结论:“温阳祛瘀”中药熏洗联合复方益母草胶囊能显著促进阳虚血瘀型子宫复旧不全产妇早期康复,有效提高产妇睡眠质量,改善不良情绪,整体治疗效果较佳。

糖尿病合并肺部感染(气虚阳亏证)证治机理探析

糖尿病合并肺部感染发病率高、死亡率高,严重威胁患者的生活质量及生命安全。中医目前多从清热或者滋阴角度治疗糖尿病合并肺部感染,但此疗法对一些糖尿病后期合并肺部感染患者疗效欠佳甚至无效,从气虚阳亏的思路治疗糖尿病合并肺部感染可以取得满意的疗效。为此,本文探寻糖尿病后期合并肺部感染(气虚阳亏证)的诊治机理,指出其病机是肺脾肾气阳虚衰,尤以脾最为关键,兼寒饮内伏,治疗核心是扶助阳气以温化促气化,以恢复机体平衡。

中国槟榔习俗研究述评

学界对槟榔习俗的研究持续了近百年,主要集中于对一些地区的槟榔习俗进行调查研究,以及对历史时期中国槟榔习俗的传播与消退及其原因进行探讨。这些研究揭示了中国槟榔习俗流行的主要地区以及槟榔在社会生活中的重要作用,但槟榔习俗形成的原因及其传播机制等关键问题并未得到解决。建议更全面地收集槟榔习俗史料,全面系统地研究嚼食槟榔习俗的原因、中国槟榔习俗形成、传播机制,为解决因嚼食槟榔而引起的社会问题提供历史参考和应对策略。

基于癌毒病机理论辨治乳腺癌肝转移

乳腺癌晚期容易发生肝转移,在癌毒理论指导下,程海波教授提出该病的核心病机为肝阴血虚,痰瘀郁结,癌毒流注。基本治疗原则为祛邪解毒、扶正固本。主要治法包括滋阴养血,柔肝和络;疏肝解郁,化痰祛瘀;通经活络,抗癌解毒。验之临床,每获良效。附验案1则以佐证。

柳国斌教授从“寒凝血瘀”论治血栓闭塞性脉管炎的经验

本文对柳国斌教授治疗血栓闭塞性脉管炎的学术思想进行总结。柳教授提出阳虚寒凝是血栓闭塞性脉管炎的始动病机,而后形成瘀血、脉络闭阻等病理环节,故将本病的病机概括为“寒凝经脉,瘀血阻络”,其提出以“温经散寒,活血通络”为治疗法则,遣方用药注重扶阳,认为机体的阳气充足后,气血得以运行顺畅,瘀血等病理因素随之消散。柳教授强调只有抓住病机才能抓住治疗的关键,在复杂的疾病中找出矛盾所在,才能取得良效。现将柳教授临证经验总结如下,并附验案1则,为治疗血栓闭塞性脉管炎提供思路。

基于玄府理论探讨风药在眼科疾病中的应用

眼科疾病发病时全身症状不显,尤其眼底疾病,以致于医者在临床辨证时常常无症可辨,此时传统的八纲辨证理论无法满足诊疗的需要。玄府理论作为一种独特的诊疗方法,为临床诊治眼病提供了新的思路。眼位至高,寻常药物所不能及,风药轻清上行,可助药力直达眼目,同时作为最常用的开玄府之品,其在眼病的治疗中占有重要地位。因此,本文以玄府理论为基础,总结眼科疾病的发病规律,结合风药辛散的生理特点,探讨风药在眼科疾病中的应用经验,提出风药通过祛风、散火、胜湿、润燥、达神等来祛除郁滞眼目的病理产物,调畅目中气血之运行,从而通利玄府通道,恢复目中神光运转功能,达到治疗内外障眼病的独特作用,以期为临床医师应用风药论治眼科疾病时提供新的理论参考。

祛风清热化湿法治疗新型冠状病毒感染后咳嗽的临床经验

[目的]总结王真教授治疗新型冠状病毒感染后咳嗽(以下简称新冠后咳嗽)的中医经验。[方法]通过记录并整理医案,参考国内外文献,从病因病机、处方经验、验案举隅三方面阐述王真教授的治疗经验。[结果]王真教授认为,新冠后咳嗽的病因是疠气,病机是风邪留恋、湿热内蕴,处方经验为祛风解表、通窍利咽,三焦湿热、分消走泄,因人制宜、标本兼顾。所举两则医案中,患者以新冠感染后反复咳嗽为主诉,王真教授以祛风清热化湿为主,养阴生津、健脾、益肾、化瘀为辅,处方周全,疗效确切。[结论]王真教授准确把握新冠后咳嗽的病因病机,治法明晰,用药严谨,疗效明显,其治疗经验具有临床价值。