BACKGROUND Hepatic steatosis is a very common problem worldwide.AIM To assess the performance of two-and six-point Dixon magnetic resonance(MR)techniques in the detection,quantification and grading of hepatic steatosi...BACKGROUND Hepatic steatosis is a very common problem worldwide.AIM To assess the performance of two-and six-point Dixon magnetic resonance(MR)techniques in the detection,quantification and grading of hepatic steatosis.METHODS A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease.MR sequences included two-point Dixon,six-point Dixon,MR spectroscopy(MRS)and MR elastography.Fat fraction(FF)estimates on the Dixon techniques were compared to the MRS-proton density FF(PDFF).Statistical tests used included Pearson’s correlation and receiver operating characteristic.RESULTS FF estimates on the Dixon techniques showed excellent correlation(≥0.95)with MRS-PDFF,and excellent accuracy[area under the receiver operating characteristic(AUROC)≥0.95]in:(1)Detecting steatosis;and(2)Grading severe steatosis,(P<0.001).In iron overload,two-point Dixon was not evaluable due to confounding T2*effects.FF estimates on six-point Dixon vs MRS-PDFF showed a moderate correlation(0.82)in iron overload vs an excellent correlation(0.97)without iron overload,(P<0.03).The accuracy of six-point Dixon in grading mild steatosis improved(AUROC:0.59 to 0.99)when iron overload cases were excluded.The excellent correlation(>0.9)between the Dixon techniques vs MRSPDFF did not change in the presence of liver fibrosis(P<0.01).CONCLUSION Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions.展开更多
目的:比较腹腔镜与Dixon直肠癌根治术的临床疗效.方法:回顾分析2006-01/2013-01在我院完成腹腔镜直肠癌根治术53例及Dixon直肠癌根治术69例,分析比较两组患者的手术时间、术中出血和术后肛门排气时间、术后并发症及近、远期疗效.结果:与...目的:比较腹腔镜与Dixon直肠癌根治术的临床疗效.方法:回顾分析2006-01/2013-01在我院完成腹腔镜直肠癌根治术53例及Dixon直肠癌根治术69例,分析比较两组患者的手术时间、术中出血和术后肛门排气时间、术后并发症及近、远期疗效.结果:与Dixon手术组相比,腹腔镜组直肠癌根治术组手术时间(165.18 min±25.45 min vs177.19 min±12.28 min,P=0.014)、术中出血量(589.85 mL±127.45 mL vs 682.30 mL±122.76 mL,P=0.004)、术后肛门排气时间(3.94 d±1.0 d vs 4.62 d±1.3 d,P=0.01),具有统计学差异,术中摘除淋巴结(3.8±1.6 vs 3.7±1.2,P=0.756)无统计学差异.术后并发症吻合口漏、切口感染、黏连性梗阻发生率低以及性功能和排尿功能满意度高,均有统计学差异(P=0.033,0.049,0.000);但两组肿瘤局部复发远处转移、5年生存率无统计学意义(P=0.701,0.583).结论:腹腔镜直肠癌根治术相比Dixon手术,其手术创伤性小、康复快、术后并发症少及性功能和排尿功能满意度高等优点.但在5年生存率、肿瘤局部复发和远处转移二者无明显差异.展开更多
文摘BACKGROUND Hepatic steatosis is a very common problem worldwide.AIM To assess the performance of two-and six-point Dixon magnetic resonance(MR)techniques in the detection,quantification and grading of hepatic steatosis.METHODS A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease.MR sequences included two-point Dixon,six-point Dixon,MR spectroscopy(MRS)and MR elastography.Fat fraction(FF)estimates on the Dixon techniques were compared to the MRS-proton density FF(PDFF).Statistical tests used included Pearson’s correlation and receiver operating characteristic.RESULTS FF estimates on the Dixon techniques showed excellent correlation(≥0.95)with MRS-PDFF,and excellent accuracy[area under the receiver operating characteristic(AUROC)≥0.95]in:(1)Detecting steatosis;and(2)Grading severe steatosis,(P<0.001).In iron overload,two-point Dixon was not evaluable due to confounding T2*effects.FF estimates on six-point Dixon vs MRS-PDFF showed a moderate correlation(0.82)in iron overload vs an excellent correlation(0.97)without iron overload,(P<0.03).The accuracy of six-point Dixon in grading mild steatosis improved(AUROC:0.59 to 0.99)when iron overload cases were excluded.The excellent correlation(>0.9)between the Dixon techniques vs MRSPDFF did not change in the presence of liver fibrosis(P<0.01).CONCLUSION Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions.
文摘目的:比较腹腔镜与Dixon直肠癌根治术的临床疗效.方法:回顾分析2006-01/2013-01在我院完成腹腔镜直肠癌根治术53例及Dixon直肠癌根治术69例,分析比较两组患者的手术时间、术中出血和术后肛门排气时间、术后并发症及近、远期疗效.结果:与Dixon手术组相比,腹腔镜组直肠癌根治术组手术时间(165.18 min±25.45 min vs177.19 min±12.28 min,P=0.014)、术中出血量(589.85 mL±127.45 mL vs 682.30 mL±122.76 mL,P=0.004)、术后肛门排气时间(3.94 d±1.0 d vs 4.62 d±1.3 d,P=0.01),具有统计学差异,术中摘除淋巴结(3.8±1.6 vs 3.7±1.2,P=0.756)无统计学差异.术后并发症吻合口漏、切口感染、黏连性梗阻发生率低以及性功能和排尿功能满意度高,均有统计学差异(P=0.033,0.049,0.000);但两组肿瘤局部复发远处转移、5年生存率无统计学意义(P=0.701,0.583).结论:腹腔镜直肠癌根治术相比Dixon手术,其手术创伤性小、康复快、术后并发症少及性功能和排尿功能满意度高等优点.但在5年生存率、肿瘤局部复发和远处转移二者无明显差异.
