In this paper, the isogeometric analysis (IGA) is employed to develop an acoustic radiation model for a double plate-acoustic cavity coupling system, with a focus on analyzing the sound transmission loss (STL). The fu...In this paper, the isogeometric analysis (IGA) is employed to develop an acoustic radiation model for a double plate-acoustic cavity coupling system, with a focus on analyzing the sound transmission loss (STL). The functionally graded (FG) plate exhibits a different material properties in-plane, and the power-law rule is adopted as the governing principle for material mixing. To validate the harmonic response and demonstrate the accuracy and convergence of the isogeometric modeling, ANASYS is utilized to compare with numerical examples. A plane wave serves as the acoustic excitation, and the Rayleigh integral is applied to discretize the radiated plate. The STL results are compared with the literature, confirming the reliability of the coupling system. Finally, the investigation is conducted to study impact of cavity depth and power-law parameter on the STL.展开更多
Young stroke patients have a strong desire to return to the society, but few studies have been conducted on their rehabilitation training items, intensity, and prognosis. We analyzed clinical data of young and middle-...Young stroke patients have a strong desire to return to the society, but few studies have been conducted on their rehabilitation training items, intensity, and prognosis. We analyzed clinical data of young and middle-aged/older stroke patients hospitalized in the Department of Neurological Rehabilitation, China Rehabilitation Research Center, Capital Medical University, China from February 2014 to May 2015. Results demonstrated that hemorrhagic stroke （59.6%） was the primary stroke type found in the young group, while ischemic stroke （60.0%） was the main type detected in the middle-aged/older group. Compared with older stroke patients, education level and incidence of hyperhomocysteinemia were higher in younger stroke patients, whereas, incidences of hypertension, diabetes, and heart disease were lower. The average length of hospital stay was longer in the young group than in the middle-aged/older group. The main risk factors observed in the young stroke patients were hypertension, drinking, smoking, hyperlipidemia, hyperhomocysteinemia, diabetes, previous history of stroke, and heart disease. The most accepted rehabilitation program consisted of physiotherapy, occupational therapy, speech therapy, acupuncture and moxibustion. Average rehabilitation training time was 2.5 hours/day. Barthel Index and modified Rankin Scale scores were increased at discharge. Six months after discharge, the degree of occupational and economic satisfaction declined, and there were no changes in family life satisfaction. The degrees of other life satisfaction （such as friendship） improved. The degree of disability and functional status improved significantly in young stroke patients after professional rehabilitation, but the number of patients who returned to society within 6 months after stroke was still small.展开更多
Objective: To explore the effect of felodipine in combined with irbesartan on the blood uric acid (UA);serum adiponectin (APN);and renal function in young males with essential hypertension (EH). Methods: A total of 13...Objective: To explore the effect of felodipine in combined with irbesartan on the blood uric acid (UA);serum adiponectin (APN);and renal function in young males with essential hypertension (EH). Methods: A total of 134 young male patients with EH who were admitted in our hospital from January;2016 to January;2017 were included in the study and randomized into the observation group and the control group. The patients in the control group were given felodipine sustanined release tablets;5 mg/time;1 time/d. On this basis;the patients in the observation group were given irbesartan;150 mg/time;1 time/d. To those whose blood pressure was not reduced under 140/90 mmHg after 4 week treatment;the dose of felodipine sustanined release tablets was increased to 10 mg/d. A maintenance dose was adopted according to the individual conditions until the ideal blood pressure reduction effect was achieved. The morning fasting venous blood was collected before treatment;4 and 12 weeks after treatment in the two groups. ELISA was used to detect APN level. Uricase-peroxide enzymic method was used to detect UA level. The full automatic biochemical analyzer was used to detect BUN and Scr. Ccr was calculated. Urine was collected. RIA was used to detect 24 h Upro. The morning fasting venous blood before treatment;24 and 48 weeks after treatment was collected. RIA was used to detect the serum T and SHBG levels. Results: Scr and 24 h Upro 4 and 12 weeks after treatment in the two groups were gradually reduced;while Ccr was gradually elevated. BUN 12 weeks after treatment in the observation group was significantly reduced. Scr and 24 h Upro 4 and 12 weeks after treatment in the observation group were significantly lower than those in the control group;while Ccr was significantly higher than that in the control group. BUNS 12 weeks after treatment in the observation group were significantly lower than those in the control group. T level 24 and 48 weeks after treatment in the two groups was significantly elevated;while SHBG after treatment was not significantly changed. T level 24 and 48 weeks after treatment in the observation group was significantly higher than that in the control group. APN 4 and 12 weeks after treatment in the two groups was significantly elevated;while UA was significantly reduced. APN 4 and 12 weeks after treatment in the observation group was significantly higher than that in the control group;while UA was significantly lower than that in the control group. Conclusions: Felodipine in combined with irbesartan in the treatment of EH in young males can effectively regulate APN and UA levels;protect the renal function;enhance the sex hormone levels;and has a great significance in reducing the target organ damage and improving the prognosis.展开更多
文摘In this paper, the isogeometric analysis (IGA) is employed to develop an acoustic radiation model for a double plate-acoustic cavity coupling system, with a focus on analyzing the sound transmission loss (STL). The functionally graded (FG) plate exhibits a different material properties in-plane, and the power-law rule is adopted as the governing principle for material mixing. To validate the harmonic response and demonstrate the accuracy and convergence of the isogeometric modeling, ANASYS is utilized to compare with numerical examples. A plane wave serves as the acoustic excitation, and the Rayleigh integral is applied to discretize the radiated plate. The STL results are compared with the literature, confirming the reliability of the coupling system. Finally, the investigation is conducted to study impact of cavity depth and power-law parameter on the STL.
基金supported by the Special Fund of Basic Scientific Research Service Fee of Central Public Welfare Scientif ic Research Institute of China,No.2014CZ-13
文摘Young stroke patients have a strong desire to return to the society, but few studies have been conducted on their rehabilitation training items, intensity, and prognosis. We analyzed clinical data of young and middle-aged/older stroke patients hospitalized in the Department of Neurological Rehabilitation, China Rehabilitation Research Center, Capital Medical University, China from February 2014 to May 2015. Results demonstrated that hemorrhagic stroke （59.6%） was the primary stroke type found in the young group, while ischemic stroke （60.0%） was the main type detected in the middle-aged/older group. Compared with older stroke patients, education level and incidence of hyperhomocysteinemia were higher in younger stroke patients, whereas, incidences of hypertension, diabetes, and heart disease were lower. The average length of hospital stay was longer in the young group than in the middle-aged/older group. The main risk factors observed in the young stroke patients were hypertension, drinking, smoking, hyperlipidemia, hyperhomocysteinemia, diabetes, previous history of stroke, and heart disease. The most accepted rehabilitation program consisted of physiotherapy, occupational therapy, speech therapy, acupuncture and moxibustion. Average rehabilitation training time was 2.5 hours/day. Barthel Index and modified Rankin Scale scores were increased at discharge. Six months after discharge, the degree of occupational and economic satisfaction declined, and there were no changes in family life satisfaction. The degrees of other life satisfaction （such as friendship） improved. The degree of disability and functional status improved significantly in young stroke patients after professional rehabilitation, but the number of patients who returned to society within 6 months after stroke was still small.
文摘Objective: To explore the effect of felodipine in combined with irbesartan on the blood uric acid (UA);serum adiponectin (APN);and renal function in young males with essential hypertension (EH). Methods: A total of 134 young male patients with EH who were admitted in our hospital from January;2016 to January;2017 were included in the study and randomized into the observation group and the control group. The patients in the control group were given felodipine sustanined release tablets;5 mg/time;1 time/d. On this basis;the patients in the observation group were given irbesartan;150 mg/time;1 time/d. To those whose blood pressure was not reduced under 140/90 mmHg after 4 week treatment;the dose of felodipine sustanined release tablets was increased to 10 mg/d. A maintenance dose was adopted according to the individual conditions until the ideal blood pressure reduction effect was achieved. The morning fasting venous blood was collected before treatment;4 and 12 weeks after treatment in the two groups. ELISA was used to detect APN level. Uricase-peroxide enzymic method was used to detect UA level. The full automatic biochemical analyzer was used to detect BUN and Scr. Ccr was calculated. Urine was collected. RIA was used to detect 24 h Upro. The morning fasting venous blood before treatment;24 and 48 weeks after treatment was collected. RIA was used to detect the serum T and SHBG levels. Results: Scr and 24 h Upro 4 and 12 weeks after treatment in the two groups were gradually reduced;while Ccr was gradually elevated. BUN 12 weeks after treatment in the observation group was significantly reduced. Scr and 24 h Upro 4 and 12 weeks after treatment in the observation group were significantly lower than those in the control group;while Ccr was significantly higher than that in the control group. BUNS 12 weeks after treatment in the observation group were significantly lower than those in the control group. T level 24 and 48 weeks after treatment in the two groups was significantly elevated;while SHBG after treatment was not significantly changed. T level 24 and 48 weeks after treatment in the observation group was significantly higher than that in the control group. APN 4 and 12 weeks after treatment in the two groups was significantly elevated;while UA was significantly reduced. APN 4 and 12 weeks after treatment in the observation group was significantly higher than that in the control group;while UA was significantly lower than that in the control group. Conclusions: Felodipine in combined with irbesartan in the treatment of EH in young males can effectively regulate APN and UA levels;protect the renal function;enhance the sex hormone levels;and has a great significance in reducing the target organ damage and improving the prognosis.
