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Leveraging Augmented Reality,Semantic-Segmentation,and VANETs for Enhanced Driver’s Safety Assistance
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作者 Sitara Afzal Imran Ullah Khan +1 位作者 Irfan Mehmood Jong Weon Lee 《Computers, Materials & Continua》 SCIE EI 2024年第1期1443-1460,共18页
Overtaking is a crucial maneuver in road transportation that requires a clear view of the road ahead.However,limited visibility of ahead vehicles can often make it challenging for drivers to assess the safety of overt... Overtaking is a crucial maneuver in road transportation that requires a clear view of the road ahead.However,limited visibility of ahead vehicles can often make it challenging for drivers to assess the safety of overtaking maneuvers,leading to accidents and fatalities.In this paper,we consider atrous convolution,a powerful tool for explicitly adjusting the field-of-view of a filter as well as controlling the resolution of feature responses generated by Deep Convolutional Neural Networks in the context of semantic image segmentation.This article explores the potential of seeing-through vehicles as a solution to enhance overtaking safety.See-through vehicles leverage advanced technologies such as cameras,sensors,and displays to provide drivers with a real-time view of the vehicle ahead,including the areas hidden from their direct line of sight.To address the problems of safe passing and occlusion by huge vehicles,we designed a see-through vehicle system in this study,we employed a windshield display in the back car together with cameras in both cars.The server within the back car was used to segment the car,and the segmented portion of the car displayed the video from the front car.Our see-through system improves the driver’s field of vision and helps him change lanes,cross a large car that is blocking their view,and safely overtake other vehicles.Our network was trained and tested on the Cityscape dataset using semantic segmentation.This transparent technique will instruct the driver on the concealed traffic situation that the front vehicle has obscured.For our findings,we have achieved 97.1% F1-score.The article also discusses the challenges and opportunities of implementing see-through vehicles in real-world scenarios,including technical,regulatory,and user acceptance factors. 展开更多
关键词 Overtaking safety augmented reality VANET V2V deep learning
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Evaluation of the Impact of Driver Behavior on Back of Queues Events in Work Zones Using the SHRP2 Naturalistic Driving Study Data
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作者 Shauna Hallmark Guillermo Basulto-Elias +1 位作者 Nicole Oneyear Omar Smadi 《Journal of Transportation Technologies》 2024年第2期179-194,共16页
The SHRP2 Naturalistic Driving Study was used to evaluate the impact of various work zone and driver characteristics on back of queue safety critical events (crash, near-crash, or conflicts) The model included 43 SCE ... The SHRP2 Naturalistic Driving Study was used to evaluate the impact of various work zone and driver characteristics on back of queue safety critical events (crash, near-crash, or conflicts) The model included 43 SCE and 209 “normal” events which were used as controls. The traces included representing 209 unique drivers. A Mixed-Effects Logistic Regression model was developed with probability of a SCE as the response variable and driver and work zone characteristics as predictor variables. The final model indicated glances over 1 second away from the driving task and following closely increased risk of an SCE by 3.8 times and 2.9 times, respectively. Average speed was negatively correlated to crash risk. This is counterintuitive since in most cases, it is expected that higher speeds are related to back of queue crashes. However, most queues form under congested conditions. As a result, vehicles encountering a back of queue would be more likely to be traveling at lower speeds. 展开更多
关键词 safety Critical Events SPEED Following Closely Glance Behavior
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基于DNV SAFETI Route模型的危险货物道路运输风险模拟
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作者 夏术军 姚丹丹 +3 位作者 于学生 刘阳 江黎丽 戚作秋 《化工管理》 2024年第9期78-81,共4页
DNV SAFETI Route运输路线模型是专业的运输活动风险评估模型,根据所有可能发生事故的地点分布潜在事故的总频率,计算出沿线的总体风险水平。选择事故场景为大孔泄漏,对发生泄漏情景引发的火灾、爆炸和毒性物质扩散事故后果进行预测。... DNV SAFETI Route运输路线模型是专业的运输活动风险评估模型,根据所有可能发生事故的地点分布潜在事故的总频率,计算出沿线的总体风险水平。选择事故场景为大孔泄漏,对发生泄漏情景引发的火灾、爆炸和毒性物质扩散事故后果进行预测。根据后果预测结果,进而可以得到周边防护目标所承受的个人风险和社会风险曲线。 展开更多
关键词 SAFETI 事故后果预测 道路运输风险模拟
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Data-driven short circuit resistance estimation in battery safety issues 被引量:2
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作者 Yikai Jia Jun Xu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2023年第4期37-44,共8页
Developing precise and fast methods for short circuit detection is crucial for preventing or mitigating the risk of safety issues of lithium-ion batteries(LIBs).In this paper,we developed a Convolutional Neural Networ... Developing precise and fast methods for short circuit detection is crucial for preventing or mitigating the risk of safety issues of lithium-ion batteries(LIBs).In this paper,we developed a Convolutional Neural Networks(CNN)based model that can quickly and precisely predict the short circuit resistance of LIB cells during various working conditions.Cycling tests of cells with an external short circuit(ESC)are produced to obtain the database and generate the training/testing samples.The samples are sequences of voltage,current,charging capacity,charging energy,total charging capacity,total charging energy with a length of 120 s and frequency of 1 Hz,and their corresponding short circuit resistances.A big database with~6×10^(5)samples are generated,covering various short circuit resistances(47~470Ω),current loading modes(Constant current-constant voltage(CC-CV)and drive cycle),and electrochemical states(cycle numbers from 1 to 300).Results show that the average relative absolute error of five random sample splits is 6.75%±2.8%.Further parametric analysis indicates the accuracy estimation benefits from the appropriate model setups:the optimized input sequence length(~120 s),feature selection(at least one total capacity-related variable),and rational model design,using multiple layers with different kernel sizes.This work highlights the capabilities of machine learning algorithms and data-driven methodologies in real-time safety risk prediction for batteries. 展开更多
关键词 Lithium-ion battery safety risk Internal short circuit Short circuit resistance Convolutional neural networks
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基于openSAFETY的功能安全通信协议研究
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作者 徐建明 周家豪 +3 位作者 陈琳 金瑶 周路顺 张扬扬 《计算机测量与控制》 2024年第10期228-235,共8页
针对数据传输可靠性低导致功能安全事故频发的问题,进行了基于POWERLINK的openSAFETY功能安全通信协议研究;在实时工业以太网协议POWERLINK的基础上设计了以PCP-AP为架构的openSAFETY安全节点,设计了基于FPGA软核处理器的POWERLINK内核... 针对数据传输可靠性低导致功能安全事故频发的问题,进行了基于POWERLINK的openSAFETY功能安全通信协议研究;在实时工业以太网协议POWERLINK的基础上设计了以PCP-AP为架构的openSAFETY安全节点,设计了基于FPGA软核处理器的POWERLINK内核层的软件硬件结构,设计了基于单片机MCU的openSAFETY安全应用接口程序以及近底层通信接口程序,搭建了以贝加莱PLC为安全控制节点的功能安全通信实验平台,依据故障分析设计了电磁干扰实验,模拟了工业现场中出现不同程度电磁干扰情况下功能安全通信平台的通信情况,并与非功能安全通信平台进行对比,验证了安全节点的可靠性和必要性。 展开更多
关键词 功能安全 工业以太网 opensafety POWERLINK 电磁干扰 FPGA
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Safety and effectiveness of butorphanol in epidural labor analgesia:A protocol for a systematic review and meta-analysis 被引量:3
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作者 Guan-Cheng Tang Man He +1 位作者 Zhen-Zhao Huang Yan Cheng 《World Journal of Clinical Cases》 SCIE 2024年第8期1416-1421,共6页
BACKGROUND Epidural analgesia is the most effective analgesic method during labor.Butorphanol administered epidurally has been shown to be a successful analgesic method during labor.However,no comprehensive study has ... BACKGROUND Epidural analgesia is the most effective analgesic method during labor.Butorphanol administered epidurally has been shown to be a successful analgesic method during labor.However,no comprehensive study has examined the safety and efficacy of using butorphanol as an epidural analgesic during labor.AIM To assess butorphanol's safety and efficacy for epidural labor analgesia.METHODS The PubMed,Cochrane Library,EMBASE,Web of Science,China National Knowledge Infrastructure,and Google Scholar databases will be searched from inception.Other types of literature,such as conference abstracts and references to pertinent reviews,will also be reviewed.We will include randomized controlled trials comparing butorphanol with other opioids combined with local anesthetics for epidural analgesia during labor.There will be no language restrictions.The primary outcomes will include the visual analog scale score for the first stage of labor,fetal effects,and Apgar score.Two independent reviewers will evaluate the full texts,extract data,and assess the risk of bias.Publication bias will be evaluated using Egger's or Begg's tests as well as visual analysis of a funnel plot,and heterogeneity will be evaluated using the Cochran Q test,P values,and I2 values.Meta-analysis,subgroup analysis,and sensitivity analysis will be performed using RevMan software version 5.4.This protocol was developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)Protocols statement,and the PRISMA statement will be used for the systematic review.RESULTS This study provides reliable information regarding the safety and efficacy of using butorphanol as an epidural analgesic during labor.CONCLUSION To support clinical practice and development,this study provides evidence-based findings regarding the safety and efficacy of using butorphanol as an epidural analgesic during labor. 展开更多
关键词 Epidural analgesia during labor BUTORPHANOL safety PROTOCOL META-ANALYSIS
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Evolutionary Decision-Making and Planning for Autonomous Driving Based on Safe and Rational Exploration and Exploitation 被引量:2
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作者 Kang Yuan Yanjun Huang +4 位作者 Shuo Yang Zewei Zhou Yulei Wang Dongpu Cao Hong Chen 《Engineering》 SCIE EI CAS CSCD 2024年第2期108-120,共13页
Decision-making and motion planning are extremely important in autonomous driving to ensure safe driving in a real-world environment.This study proposes an online evolutionary decision-making and motion planning frame... Decision-making and motion planning are extremely important in autonomous driving to ensure safe driving in a real-world environment.This study proposes an online evolutionary decision-making and motion planning framework for autonomous driving based on a hybrid data-and model-driven method.First,a data-driven decision-making module based on deep reinforcement learning(DRL)is developed to pursue a rational driving performance as much as possible.Then,model predictive control(MPC)is employed to execute both longitudinal and lateral motion planning tasks.Multiple constraints are defined according to the vehicle’s physical limit to meet the driving task requirements.Finally,two principles of safety and rationality for the self-evolution of autonomous driving are proposed.A motion envelope is established and embedded into a rational exploration and exploitation scheme,which filters out unreasonable experiences by masking unsafe actions so as to collect high-quality training data for the DRL agent.Experiments with a high-fidelity vehicle model and MATLAB/Simulink co-simulation environment are conducted,and the results show that the proposed online-evolution framework is able to generate safer,more rational,and more efficient driving action in a real-world environment. 展开更多
关键词 Autonomous driving DECISION-MAKING Motion planning Deep reinforcement learning Model predictive control
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Influences of Mixed Traffic Flow and Time Pressure on Mistake-Prone Driving Behaviors among Bus Drivers
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作者 Vu Van-Huy Hisashi Kubota 《Journal of Transportation Technologies》 2023年第3期389-410,共22页
Bus safety is a matter of great importance in many developing countries, with driving behaviors among bus drivers identified as a primary factor contributing to accidents. This concern is particularly amplified in mix... Bus safety is a matter of great importance in many developing countries, with driving behaviors among bus drivers identified as a primary factor contributing to accidents. This concern is particularly amplified in mixed traffic flow (MTF) environments with time pressure (TP). However, there is a lack of sufficient research exploring the relationships among these factors. This study consists of two papers that aim to investigate the impact of MTF environments with TP on the driving behaviors of bus drivers. While the first paper focuses on violated driving behaviors, this particular paper delves into mistake-prone driving behaviors (MDB). To collect data on MDB, as well as perceptions of MTF and TP, a questionnaire survey was implemented among bus drivers. Factor analyses were employed to create new measurements for validating MDB in MTF environments. The study utilized partial correlation and linear regression analyses with the Bayesian Model Averaging (BMA) method to explore the relationships between MDB and MTF/TP. The results revealed a modified scale for MDB. Two MTF factors and two TP factors were found to be significantly associated with MDB. A high presence of motorcycles and dangerous interactions among vehicles were not found to be associated with MDB among bus drivers. However, bus drivers who perceived motorcyclists as aggressive, considered road users’ traffic habits as unsafe, and perceived bus routes’ punctuality and organization as very strict were more likely to exhibit MDB. Moreover, the results from the three MDB predictive models demonstrated a positive impact of bus route organization on MDB among bus drivers. The study also examined various relationships between the socio-demographic characteristics of bus drivers and MDB. These findings are of practical significance in developing interventions aimed at reducing MDB among bus drivers operating in MTF environments with TP. 展开更多
关键词 Bus safety Mistake-Prone driving Behavior Mixed Traffic Time Pressure Factor Analyses Bayesian Model Averaging
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Thermal safety boundary of lithium-ion battery at different state of charge 被引量:1
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作者 Hang Wu Siqi Chen +8 位作者 Yan Hong Chengshan Xu Yuejiu Zheng Changyong Jin Kaixin Chen Yafei He Xuning Feng Xuezhe Wei Haifeng Dai 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第4期59-72,共14页
Thermal runaway(TR)is a critical issue hindering the large-scale application of lithium-ion batteries(LIBs).Understanding the thermal safety behavior of LIBs at the cell and module level under different state of charg... Thermal runaway(TR)is a critical issue hindering the large-scale application of lithium-ion batteries(LIBs).Understanding the thermal safety behavior of LIBs at the cell and module level under different state of charges(SOCs)has significant implications for reinforcing the thermal safety design of the lithium-ion battery module.This study first investigates the thermal safety boundary(TSB)correspondence at the cells and modules level under the guidance of a newly proposed concept,safe electric quantity boundary(SEQB).A reasonable thermal runaway propagation(TRP)judgment indicator,peak heat transfer power(PHTP),is proposed to predict whether TRP occurs.Moreover,a validated 3D model is used to quantitatively clarify the TSB at different SOCs from the perspective of PHTP,TR trigger temperature,SOC,and the full cycle life.Besides,three different TRP transfer modes are discovered.The interconversion relationship of three different TRP modes is investigated from the perspective of PHTP.This paper explores the TSB of LIBs under different SOCs at both cell and module levels for the first time,which has great significance in guiding the thermal safety design of battery systems. 展开更多
关键词 Lithium-ion battery Battery safety Thermal runaway State of charge Numerical analysis
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Efficacy and safety of minimally invasive laparoscopic surgery under general anesthesia for ovarian cancer 被引量:1
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作者 Xian Qin Chen Chen +4 位作者 Yang Liu Xian-Hong Hua Jia-Yi Li Meng-Jie Liang Fang Wu 《World Journal of Clinical Cases》 SCIE 2024年第9期1569-1577,共9页
BACKGROUND Ovarian cancer is one of the most common malignant tumors in female reproductive system in the world,and the choice of its treatment is very important for the survival rate and prognosis of patients.Traditi... BACKGROUND Ovarian cancer is one of the most common malignant tumors in female reproductive system in the world,and the choice of its treatment is very important for the survival rate and prognosis of patients.Traditional open surgery is the main treatment for ovarian cancer,but it has the disadvantages of big trauma and slow recovery.With the continuous development of minimally invasive technology,minimally invasive laparoscopic surgery under general anesthesia has been gradually applied to the treatment of ovarian cancer because of its advantages of less trauma and quick recovery.However,the efficacy and safety of minimally invasive laparoscopic surgery under general anesthesia in the treatment of ovarian cancer are still controversial.AIM To explore the efficacy and safety of general anesthesia minimally invasive surgery in the treatment of ovarian cancer.METHODS The clinical data of 90 patients with early ovarian cancer in our hospital were analyzed retrospectively.According to the different surgical treatment methods,patients were divided into study group and control group(45 cases in each group).The study group received minimally invasive laparoscopic surgery under general anesthesia for ovarian cancer,while the control group received traditional open surgery for ovarian cancer.The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire(EORTC QLQ-C30),clinical efficacy and safety of the two groups were compared.RESULTS The intraoperative blood loss,length of hospital stay,postoperative gas evacuation time,and postoperative EORTC QLQ-C30 score of the study group were significantly better than those of the control group(P<0.05).The incidence of postoperative complications in the study group was significantly lower than in the control group(P<0.05).The two groups had no significant differences in the preoperative adrenocorticotropic hormone(ACTH),androstenedione(AD),cortisol(Cor),cluster of differentiation 3 positive(CD3+),and cluster of differentiation 4 positive(CD4+)indexes(P>0.05).In contrast,postoperatively,the study group's ACTH,AD,and Cor indexes were lower,and the CD3+and CD4+indexes were higher than those in the control group(P<0.05).CONCLUSION Minimally invasive laparoscopic surgery under general anesthesia in patients with early ovarian cancer can significantly improve the efficacy and safety,improve the short-term prognosis and quality of life of patients,and is worth popularizing. 展开更多
关键词 Early-stage ovarian cancer EFFICACY Minimally invasive LAPAROSCOPY safety SURGERY
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Effect of safety valve types on the gas venting behavior and thermal runaway hazard severity of large-format prismatic lithium iron phosphate batteries 被引量:2
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作者 Zhuangzhuang Jia Yuanyuan Min +5 位作者 Peng Qin Wenxin Mei Xiangdong Meng Kaiqiang Jin Jinhua Sun Qingsong Wang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第2期195-207,I0006,共14页
The safety valve is an important component to ensure the safe operation of lithium-ion batteries(LIBs).However,the effect of safety valve type on the thermal runaway(TR)and gas venting behavior of LIBs,as well as the ... The safety valve is an important component to ensure the safe operation of lithium-ion batteries(LIBs).However,the effect of safety valve type on the thermal runaway(TR)and gas venting behavior of LIBs,as well as the TR hazard severity of LIBs,are not known.In this paper,the TR and gas venting behavior of three 100 A h lithium iron phosphate(LFP)batteries with different safety valves are investigated under overheating.Compared to previous studies,the main contribution of this work is in studying and evaluating the effect of gas venting behavior and TR hazard severity of LFP batteries with three safety valve types.Two significant results are obtained:(Ⅰ)the safety valve type dominates over gas venting pressure of battery during safety venting,the maximum gas venting pressure of LFP batteries with a round safety valve is 3320 Pa,which is one order of magnitude higher than other batteries with oval or cavity safety valve;(Ⅱ)the LFP battery with oval safety valve has the lowest TR hazard as shown by the TR hazard assessment model based on gray-fuzzy analytic hierarchy process.This study reveals the effect of safety valve type on TR and gas venting,providing a clear direction for the safety valve design. 展开更多
关键词 Lithium iron phosphate battery safety valve Thermal runaway Gas venting behavior Thermal runaway hazard severity Gray-fuzzy analytic hierarchy process
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Safety and effectiveness of neuromuscular electrical stimulation in cardiac surgery:A systematic review 被引量:2
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作者 Christos Kourek Marios Kanellopoulos +4 位作者 Vasiliki Raidou Michalis Antonopoulos Eleftherios Karatzanos Irini Patsaki Stavros Dimopoulos 《World Journal of Cardiology》 2024年第1期27-39,共13页
BACKGROUND Lack of mobilization and prolonged stay in the intensive care unit(ICU)are major factors resulting in the development of ICU-acquired muscle weakness(ICUAW).ICUAW is a type of skeletal muscle dysfunction an... BACKGROUND Lack of mobilization and prolonged stay in the intensive care unit(ICU)are major factors resulting in the development of ICU-acquired muscle weakness(ICUAW).ICUAW is a type of skeletal muscle dysfunction and a common complication of patients after cardiac surgery,and may be a risk factor for prolonged duration of mechanical ventilation,associated with a higher risk of readmission and higher mortality.Early mobilization in the ICU after cardiac surgery has been found to be low with a significant trend to increase over ICU stay and is also associated with a reduced duration of mechanical ventilation and ICU length of stay.Neuromuscular electrical stimulation(NMES)is an alternative modality of exercise in patients with muscle weakness.A major advantage of NMES is that it can be applied even in sedated patients in the ICU,a fact that might enhance early mobilization in these patients.AIM To evaluate safety,feasibility and effectiveness of NMES on functional capacity and muscle strength in patients before and after cardiac surgery.METHODS We performed a search on Pubmed,Physiotherapy Evidence Database(PEDro),Embase and CINAHL databases,selecting papers published between December 2012 and April 2023 and identified published randomized controlled trials(RCTs)that included implementation of NMES in patients before after cardiac surgery.RCTs were assessed for methodological rigor and risk of bias via the PEDro.The primary outcomes were safety and functional capacity and the secondary outcomes were muscle strength and function.RESULTS Ten studies were included in our systematic review,resulting in 703 participants.Almost half of them performed NMES and the other half were included in the control group,treated with usual care.Nine studies investigated patients after cardiac surgery and 1 study before cardiac surgery.Functional capacity was assessed in 8 studies via 6MWT or other indices,and improved only in 1 study before and in 1 after cardiac surgery.Nine studies explored the effects of NMES on muscle strength and function and,most of them,found increase of muscle strength and improvement in muscle function after NMES.NMES was safe in all studies without any significant complication.CONCLUSION NMES is safe,feasible and has beneficial effects on muscle strength and function in patients after cardiac surgery,but has no significant effect on functional capacity. 展开更多
关键词 Neuromuscular electrical stimulation Cardiac surgery coronary artery bypass grafting Heart valve replacement Peak VO2 safety
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On Dual-Mode Driving Control Method for a Novel Unmanned Tractor With High Safety and Reliability
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作者 Wei Lu Jiacheng Li +2 位作者 Huanhuan Qin Lei Shu Aiguo Song 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第1期254-271,共18页
Due to the non-standardization and complexity of the farmland environment,it is always a huge challenge for tractors to achieve fully autonomy(work at Self-driving mode)all the time in agricultural industry.Whereas,wh... Due to the non-standardization and complexity of the farmland environment,it is always a huge challenge for tractors to achieve fully autonomy(work at Self-driving mode)all the time in agricultural industry.Whereas,when tractors work in the Tele-driving(or Remote driving)mode,the operators are prone to fatigue because they need to concentrate for long periods of time.In response to these,a dual-mode control strategy was proposed to integrate the advantages of both approaches,i.e.,by combing Self-driving at most of the time with Tele-driving under special(complex and hazardous)conditions through switching control method.First,the state switcher was proposed,which is used for smooth switching the driving modes according to different working states of a tractor.Then,the state switching control law and the corresponding subsystem tracking controllers were designed.Finally,the effectiveness and superiority of the dualmode control method were evaluated via actual experimental testing of a tractor whose results show that the proposed control method can switch smoothly,stably,and efficiently between the two driving modes automatically.The average control accuracy has been improved by 20%and 15%respectively,compared to the conventional Tele-driving control and Self-driving control with low-precision navigation.In conclusion,the proposed dualmode control method can not only satisfy the operation in the complex and changeable farmland environment,but also free drivers from high-intensity and fatiguing work.This provides a perfect application solution and theoretical support for the intelligentization of unmanned farm agricultural machinery with high safety and reliability. 展开更多
关键词 Dual-mode control safety and reliability self-driving(SD) tele-driving(TD) unmanned tractor
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Computerized tomography-guided therapeutic percutaneous puncture catheter drainage-combined with somatostatin for severe acute pancreatitis: An analysis of efficacy and safety 被引量:1
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作者 Xue-Lan Zheng Wan-Ling Li +1 位作者 Yan-Ping Lin Ting-Long Huang 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第1期59-66,共8页
BACKGROUND Severe acute pancreatitis(SAP),a condition with rapid onset,critical condition and unsatisfactory prognosis,poses a certain threat to human health,warranting optimization of relevant treatment plans to impr... BACKGROUND Severe acute pancreatitis(SAP),a condition with rapid onset,critical condition and unsatisfactory prognosis,poses a certain threat to human health,warranting optimization of relevant treatment plans to improve treatment efficacy.AIM To evaluate the efficacy and safety of computerized tomography-guided the-rapeutic percutaneous puncture catheter drainage(CT-TPPCD)combined with somatostatin(SS)in the treatment of SAP.METHODS Forty-two SAP patients admitted to The Second Affiliated Hospital of Fujian Medical University from June 2020 to June 2023 were selected.On the basis of routine treatment,20 patients received SS therapy(control group)and 22 patients were given CT-TPPCD plus SS intervention(research group).The efficacy,safety(pancreatic fistula,intra-abdominal hemorrhage,sepsis,and organ dysfunction syndrome),abdominal bloating and pain relief time,bowel recovery time,hospital stay,inflammatory indicators(C-reactive protein,interleukin-6,and pro-calcitonin),and Acute Physiology and Chronic Health Evaluation(APACHE)II score of both groups were evaluated for comparison.RESULTS Compared with the control group,the research group had a markedly higher total effective rate,faster abdominal bloating and pain relief and bowel recovery,INTRODUCTION Pancreatitis,an inflammatory disease occurring in the pancreatic tissue,is classified as either acute or chronic and is associated with high morbidity and mortality,imposing a socioeconomic burden[1,2].The pathogenesis of this disease involves early protease activation,activation of nuclear factor kappa-B-related inflammatory reactions,and infiltration of immune cells[3].Severe acute pancreatitis(SAP)is a serious condition involving systemic injury and subsequent possible organ failure,accounting for 20%of all acute pancreatitis cases[4].SAP is also characterized by rapid onset,critical illness and unsatisfactory prognosis and is correlated with serious adverse events such as systemic inflammatory response syn-drome and acute lung injury,threatening the health of patients[5,6].Therefore,timely and effective therapeutic inter-ventions are of great significance for improving patient prognosis and ensuring therapeutic effects.Somatostatin(SS),a peptide hormone that can be secreted by endocrine cells and the central nervous system,is in-volved in the regulatory mechanism of glucagon and insulin synthesis in the pancreas[7].It has complex and pleiotropic effects on the gastrointestinal tract,which can inhibit the release of gastrointestinal hormones and negatively modulate the exocrine function of the stomach,pancreas and bile,while exerting a certain influence on the absorption of the di-gestive system[8,9].SS has shown certain clinical effectiveness when applied to SAP patients and can regulate the severity of SAP and immune inflammatory responses,and this regulation is related to its influence on leukocyte apoptosis and adhesion[10,11].Computerized tomography-guided therapeutic percutaneous puncture catheter drainage(CT-TPPCD)is a surgical procedure to collect lesion fluid and pus samples from necrotic lesions and perform puncture and drainage by means of CT image examination and precise positioning[12].In the research of Liu et al[13],CT-TPPCD applied to pa-tients undergoing pancreatic surgery contributes to not only good curative effects but also a low surgical risk.Baudin et al[14]also reported that CT-TPPCD has a clinical success rate of 64.6%in patients with acute infectious necrotizing pan-creatitis,with nonfatal surgery-related complications found in only two cases,suggesting that this procedure is clinically effective and safe in the treatment of the disease.In light of the limited studies on the efficacy and safety of SS plus CT-TPPCD in SAP treatment,this study performed a relevant analysis to improve clinical outcomes in SAP patients. 展开更多
关键词 Computerized tomography guidance Therapeutic percutaneous puncture catheter drainage SOMATOSTATIN Severe acute pancreatitis Efficacy and safety
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Driving pressure in mechanical ventilation:A review 被引量:2
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作者 Syeda Farheen Zaidi Asim Shaikh +2 位作者 Daniyal Aziz Khan Salim Surani Iqbal Ratnani 《World Journal of Critical Care Medicine》 2024年第1期15-27,共13页
Driving pressure(ΔP)is a core therapeutic component of mechanical ventilation(MV).Varying levels ofΔP have been employed during MV depending on the type of underlying pathology and severity of injury.However,ΔP lev... Driving pressure(ΔP)is a core therapeutic component of mechanical ventilation(MV).Varying levels ofΔP have been employed during MV depending on the type of underlying pathology and severity of injury.However,ΔP levels have also been shown to closely impact hard endpoints such as mortality.Considering this,conducting an in-depth review ofΔP as a unique,outcome-impacting therapeutic modality is extremely important.There is a need to understand the subtleties involved in making sureΔP levels are optimized to enhance outcomes and minimize harm.We performed this narrative review to further explore the various uses ofΔP,the different parameters that can affect its use,and how outcomes vary in different patient populations at different pressure levels.To better utilizeΔP in MV-requiring patients,additional large-scale clinical studies are needed. 展开更多
关键词 driving pressure Acute respiratory distress syndrome MORTALITY Positive end-expiratory pressure Ventilator induced lung injury Mechanical ventilation
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A holistic approach to improving safety for battery energy storage systems
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作者 James Close Jonathan E.Barnard +1 位作者 Y.M.John Chew Semali Perera 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第5期422-439,共18页
The integration of battery energy storage systems(BESS)throughout our energy chain poses concerns regarding safety,especially since batteries have high energy density and numerous BESS failure events have occurred.Wid... The integration of battery energy storage systems(BESS)throughout our energy chain poses concerns regarding safety,especially since batteries have high energy density and numerous BESS failure events have occurred.Wider spread adoption will only increase the prevalence of these failure events unless there is a step change in the management and design of BESS.To understand the causes of failure,the main challenges of BESS safety are summarised.BESS consequences and failure events are discussed,including specific focus on the chain of events causing thermal runaway,and a case study of a BESS explosion in Surprise Arizona is analysed.Based on the technology and past events,a paradigm shift is required to improve BESS safety.In this review,a holistic approach is proposed.This combines currently adopted approaches including battery cell testing,lumped cell mathematical modelling,and calorimetry,alongside additional measures taken to ensure BESS safety including the requirement for computational fluid dynamics and kinetic modelling,assessment of installation level testing of the full BESS system and not simply a single cell battery test,hazard and layers of protection analysis,gas chromatography,and composition testing.The holistic approach proposed in this study aims to address challenges of BESS safety and form the basis of a paradigm shift in the safety management and design of these systems. 展开更多
关键词 Energy storagesystems Process safety Battery safety Thermal safety
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A perspective on the key factors of safety for rechargeable magnesium batteries
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作者 Shuangshuang Tan Jie Xu +5 位作者 Rongrui Deng Qiannan Zhao Chaohe Xu Guangsheng Huang Jingfeng Wang Fusheng Pan 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第7期656-676,共21页
Rechargeable Mg batteries(RMBs)have become one of the best subsitutes for lithium-ion batteries due to the high volumetric capacity,abundant resources,and uniform plating behavior of Mg metal anode.However,the safety ... Rechargeable Mg batteries(RMBs)have become one of the best subsitutes for lithium-ion batteries due to the high volumetric capacity,abundant resources,and uniform plating behavior of Mg metal anode.However,the safety hazard induced by the formation of high-modulue Mg dendrites under a high current density(10 mA cm^(-1))was still revealed in recent years.It has forced researchers to re-examine the safety of RMBs.In this review,the intrinsic safety factors of key components in RMBs,such as uneven plating,pitting and flammability of Mg anode,heat release and crystalline water decomposition of cathode,strong corrosion,low oxidition stability and flammability of electrolytes,and soforth,are systematacially summarized.Their origins,formation mechanisms,and possible safety hazards are deeply discussed.To develop high-performance Mg anode,current strategies including designing artificial SEI,three-dimensional substrates,and Mg alloys are summarized.For practical electrolytes,the configurations of boron-centered anions and simple Mg salts and the functionalized solvent with high boiling point and low flammability are suggested to comprehensively design.In addition,the future study should more focus on the investigation on the thermal runaway and decomposition of cathode materials and separa-tors.This review aims to provide fundamental insights into the relationship between electrochemistry and safety,further promoting the sustainable development of RMBs. 展开更多
关键词 Rechargeable Mg batteries Battery safety Mg dendrites Electrolyte decomposition Intrinsic safety issues
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Efficacy and Safety of Combined Bedaquiline and Delamanid Use among Patients with Multidrug-Resistant Tuberculosis in Beijing,China
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作者 Can Guo Lihui Nie +6 位作者 Yanhua Song Rongmei Liu Xiaoguang Wu Yuanyuan Shang Xuxia Zhang Yu Pang Mengqiu Gao 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第10期1195-1203,共9页
Objectives The combined use of bedaquiline and delamanid(BDQ-DLM)is limited by an increased risk of prolonging the QTc interval.We retrospectively evaluated patients who received DLM/BDQcontaining regimens at a TB-spe... Objectives The combined use of bedaquiline and delamanid(BDQ-DLM)is limited by an increased risk of prolonging the QTc interval.We retrospectively evaluated patients who received DLM/BDQcontaining regimens at a TB-specialized hospital.We aimed to present clinical efficacy and safety data for Chinese patients.Methods This case-control study included patients with multidrug-resistant tuberculosis(MDR-TB)treated with BDQ alone or BDQ plus DLM.Results A total of 96 patients were included in this analysis:64 in the BDQ group and 32 in the BDQ+DLM group.Among the 96 patients with positive sputum culture at the initiation of BDQ alone or BDQ combined with DLM,46 patients(71.9%)in the BDQ group and 29(90.6%)in the BDQ-DLM group achieved sputum culture conversion during treatment.The rate of sputum culture conversion did not differ between the two groups.The time to sputum culture conversion was significantly shorter in the BDQ-DLM group than in the BDQ group.The most frequent adverse event was QTc interval prolongation;however,the frequency of adverse events did not differ between the groups.Conclusion In conclusion,our results demonstrate that the combined use of BDQ and DLM is efficacious and tolerable in Chinese patients infected with MDR-TB.Patients in the BDQ-DLM group achieved sputum culture conversion sooner than those in the BDQ group. 展开更多
关键词 Multidrug resistant TUBERCULOSIS Bedaquiline Delamanid EFFICACY safety
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Self-assembly of perovskite nanocrystals:From driving forces to applications
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作者 Yi Li Fei Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第1期561-578,I0013,共19页
Self-assembly of metal halide perovskite nanocrystals(NCs)into superlattices can exhibit unique collective properties,which have significant application values in the display,detector,and solar cell field.This review ... Self-assembly of metal halide perovskite nanocrystals(NCs)into superlattices can exhibit unique collective properties,which have significant application values in the display,detector,and solar cell field.This review discusses the driving forces behind the self-assembly process of perovskite NCs,and the commonly used self-assembly methods and different self-assembly structures are detailed.Subsequently,we summarize the collective optoelectronic properties and application areas of perovskite superlattice structures.Finally,we conclude with an outlook on the potential issues and future challenges in developing perovskite NCs. 展开更多
关键词 SELF-ASSEMBLY Metal halide perovskite NANOCRYSTALS driving forces
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Effects of drive imbalance on the particle emission from a Bose-Einstein condensate in a one-dimensional lattice
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作者 赖龙泉 李照 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期238-243,共6页
Time-periodic driving has been an effective tool in the field of nonequilibrium quantum dynamics,which enables precise control of the particle interactions.We investigate the collective emission of particles from a Bo... Time-periodic driving has been an effective tool in the field of nonequilibrium quantum dynamics,which enables precise control of the particle interactions.We investigate the collective emission of particles from a Bose-Einstein condensate in a one-dimensional lattice with periodic drives that are separate in modulation amplitudes and relative phases.In addition to the enhancement of particle emission,we find that amplitude imbalances lead to energy shift and band broadening,while typical relative phases may give rise to similar gaps.These results offer insights into the specific manipulations of nonequilibrium quantum systems with tone-varying drives. 展开更多
关键词 Bose-Einstein condensate particle emission periodic drive
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