Herein we summarized some clean preparation examples to emphasize the concept of dual roles design(or named as "two birds one stone strategy") in green and sustainable chemistry.In those examples,the reactan...Herein we summarized some clean preparation examples to emphasize the concept of dual roles design(or named as "two birds one stone strategy") in green and sustainable chemistry.In those examples,the reactants and/or solvent play dual roles rendering a cleaner organic preparation process.Consequently,both the chemical waste and manufacturing cost could be reduced.展开更多
An energy-saving and eco-friendly method for the efficient construction of various tri-and tetrasubstituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes,...An energy-saving and eco-friendly method for the efficient construction of various tri-and tetrasubstituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes,TMSCN and N,N-disubstituted formamides within 40 min under metal-,solvent-free and mild conditions was developed.The dual role of iodine(catalyst and oxidant)notably simplified the reaction conditions and reduced the chemical waste generated.展开更多
Novel and efficient Mn(OAc)_(3)·2 H_(2)O promoted radical addition-[4+1]cyclization relay of 3-indolymethanols and phosphites was disclosed,which afforded 1,2-oxaphospholoindole derivatives in moderate to good yi...Novel and efficient Mn(OAc)_(3)·2 H_(2)O promoted radical addition-[4+1]cyclization relay of 3-indolymethanols and phosphites was disclosed,which afforded 1,2-oxaphospholoindole derivatives in moderate to good yields.Based on the experimental and computational studies,a mechanism involving radical addition and intramolecular cyclization cascade was proposed.展开更多
基金financial support from the National Natural Science Foundation of China(Nos.21545010 and 31527803)Hunan Provincial Natural Science Foundation of China(No. 2019JJ20008)
文摘Herein we summarized some clean preparation examples to emphasize the concept of dual roles design(or named as "two birds one stone strategy") in green and sustainable chemistry.In those examples,the reactants and/or solvent play dual roles rendering a cleaner organic preparation process.Consequently,both the chemical waste and manufacturing cost could be reduced.
基金the Hunan Provincial Natural Science Foundation of China(Nos.2018JJ3215 and 2019JJ20008)the Research Foundation of Education Bureau of Hunan Province(No.18C0147)Double first-class construction project of Hunan Agricultural University(No.SYL2019064)。
文摘An energy-saving and eco-friendly method for the efficient construction of various tri-and tetrasubstituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes,TMSCN and N,N-disubstituted formamides within 40 min under metal-,solvent-free and mild conditions was developed.The dual role of iodine(catalyst and oxidant)notably simplified the reaction conditions and reduced the chemical waste generated.
基金the National Natural Science Foundation of China(Nos.21772138 and 21672157)the project of scientific and technologic infrastructure of Suzhou(No.SZS201708)PAPD。
文摘Novel and efficient Mn(OAc)_(3)·2 H_(2)O promoted radical addition-[4+1]cyclization relay of 3-indolymethanols and phosphites was disclosed,which afforded 1,2-oxaphospholoindole derivatives in moderate to good yields.Based on the experimental and computational studies,a mechanism involving radical addition and intramolecular cyclization cascade was proposed.