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Analytical solutions to edge effect of composite laminates based on symplectic dual system
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作者 姚伟岸 聂臆瞩 肖锋 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2011年第9期1091-1100,共10页
In the symplectic space composed of the original variables,displacements,and their dual variables,stresses,the symplectic solution for the composite laminates based on the Pipes-Pagano model is established in this pap... In the symplectic space composed of the original variables,displacements,and their dual variables,stresses,the symplectic solution for the composite laminates based on the Pipes-Pagano model is established in this paper.In contrast to the traditional technique using only one kind of variables,the symplectic dual variables include displacement components as well as stress components.Therefore,the compatibility conditions of displacement and stress at interfaces can be formulated simultaneously.After being introduced into the symplectic dual system,the uniform schemes,such as the separation of variables and symplectic eigenfunction expansion method,can be implemented conveniently to analyze composite laminate problems.An analytical solution for the free edge effect of composite laminates is obtained,showing the effectiveness of the symplectic dual method in analyzing composite laminates. 展开更多
关键词 composite laminates edge effect Pipes-Pagano model interlaminar stresses symplectic dual system
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The Empirical Study on Chinese Style Dual System Basing on Foxconn Training Base Program
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作者 Guo Nan(Tianjin University of Technology and Education School of Vocational Education,Tianjin 300222 China) 《教育教学论坛》 2012年第19期52-54,共3页
So far many existing papers have made study on dual system.While most scholars take the opinion that dual system can give obviously positive effect to skilled talent training,some theorists argue that the precondition... So far many existing papers have made study on dual system.While most scholars take the opinion that dual system can give obviously positive effect to skilled talent training,some theorists argue that the precondition of dual system performs excellently is dual system should be localized according to the reality of a country or a district.This paper analyzes dual system practice in China from an example of Foxconn Training Base,the conclusion is that in Foxconn Training Base Program,dual system has been localized successfully and evolved into triangle system,and this program management pattern can be used in other areas of China as a mature,standard Chinese dual system pattern for skilled talent training. 展开更多
关键词 skilled talent training dual system Foxconn Training Base
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The Enlightenment of German “Dual System” to China's Vocational Education Reform
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作者 Xinyi Han Yin Zhang 《Journal of Contemporary Educational Research》 2020年第12期60-63,共4页
This article analyzes the enlightenment of studying the German"dual system"under the new situation for our country's promotion of enterprises to participate in vocational education and elaborates on the ... This article analyzes the enlightenment of studying the German"dual system"under the new situation for our country's promotion of enterprises to participate in vocational education and elaborates on the nature of German"dual system"of skills training,the core role of enterprises and the motivation of economic subsidies.Based on expounding the current situation of our vocational education,this article focuses on the analysis of key issues affecting the quality of vocational education in our country and the reasons why Chinese enterprises lack motivation to participate in vocational education.Finally,based on the enlightenment of Germany's"dual system",it is pointed out that our country's vocational education reform should adopt effective measures of economic subsidies to strengthen the motivation of enterprises to participate in vocational education. 展开更多
关键词 German"dual system" Vocational education Enterprise participation Lack of motivation Economic subsidies
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Improving Audit Judgment and Decision Making With Dual Systems Cognitive Model
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作者 Philip Yim Kwong Cheng 《Journal of Modern Accounting and Auditing》 2011年第10期1060-1069,共10页
This article proposes a dual system cognitive reasoning model to enhance audit judgment and decision making. The model is built on the fact that the total cognitive capacity of an individual comprises two systems of r... This article proposes a dual system cognitive reasoning model to enhance audit judgment and decision making. The model is built on the fact that the total cognitive capacity of an individual comprises two systems of reasoning--System 1 that is unconscious, associative, implicit, more emotional and less controlled, and so forth; and System 2 that is conscious, explicit, deliberate and rule-governed, and so forth. The benefits of the proposed model that integrates these two complementary and compensatory systems are first illustrated with an example in audit planning, and second explained how the model could overcome the deficiencies of heuristics specifically in an audit context. 展开更多
关键词 dual cognitive systems audit judgment and decision HEURISTICS
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Practice and Reflection on the Apprentice Training Talents “Dual Systems Four Stages of Work Integrated Learning” Education Approach
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作者 Shuai Tian 《Journal of World Architecture》 2018年第2期20-27,共8页
In view of the current demand for skilled talents required by the Chinese construction industry,this paper takes the Jiuzhou Polytechnic of Xuzhou,Jiangsu Province as an example and puts forward the apprenticeship tra... In view of the current demand for skilled talents required by the Chinese construction industry,this paper takes the Jiuzhou Polytechnic of Xuzhou,Jiangsu Province as an example and puts forward the apprenticeship training model of“dual system,four stages of work integrated learning,”with the characteristics of vocational education from China Jiuzhou Polytechnic along with its paid study courses. 展开更多
关键词 SKILL type dual systems four-stages APPRENTICESHIP training APPROACH PRACTICE
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Dynamic optimal allocation of energy storage systems integrated within photovoltaic based on a dual timescale dynamics model
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作者 Kecun Li Zhenyu Huang +2 位作者 Youbo Liu Yaser Qudaih Junyong Liu 《Global Energy Interconnection》 EI CSCD 2024年第4期415-428,共14页
Energy storage systems(ESSs)operate as independent market participants and collaborate with photovoltaic(PV)generation units to enhance the flexible power supply capabilities of PV units.However,the dynamic variations... Energy storage systems(ESSs)operate as independent market participants and collaborate with photovoltaic(PV)generation units to enhance the flexible power supply capabilities of PV units.However,the dynamic variations in the profitability of ESSs in the electricity market are yet to be fully understood.This study introduces a dual-timescale dynamics model that integrates a spot market clearing(SMC)model into a system dynamics(SD)model to investigate the profit-aware capacity growth of ESSs and compares the profitability of independent energy storage systems(IESSs)with that of an ESS integrated within a PV(PV-ESS).Furthermore,this study aims to ascertain the optimal allocation of the PV-ESS.First,SD and SMC models were set up.Second,the SMC model simulated on an hourly timescale was incorporated into the SD model as a subsystem,a dual-timescale model was constructed.Finally,a development simulation and profitability analysis was conducted from 2022 to 2040 to reveal the dynamic optimal range of PV-ESS allocation.Additionally,negative electricity prices were considered during clearing processes.The simulation results revealed differences in profitability and capacity growth between IESS and PV-ESS,helping grid investors and policymakers to determine the boundaries of ESSs and dynamic optimal allocation of PV-ESSs. 展开更多
关键词 Optimal allocation Profitability analysis PHOTOVOLTAIC Energy storage system dual timescale dynamics model Spot market clearing
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Liposomal dual delivery systems in visceral leishmaniasis enhance the synergistic effects of combination therapy:A promise for the future
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作者 Raghunath Hazra Amrita Kar Santanu Kar Mahapatra 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2024年第2期47-60,共14页
Visceral leishmaniasis(VL)is a neglected tropical disease,and this review has summarized the current treatment scenario and its prospects.It also highlights alternative approaches used by research groups in India and ... Visceral leishmaniasis(VL)is a neglected tropical disease,and this review has summarized the current treatment scenario and its prospects.It also highlights alternative approaches used by research groups in India and around the world to develop cutting-edge and potent anti-leishmanial treatments.Even though numerous medications could be utilized to treat VL,the limitations of current treatments including their toxicity,cost,route of administration,and duration of doses,have contributed to the emergence of resistance.Combination therapy might be a better option due to its shorter duration,easier route of administration,and ability to extend the lifespan of individual drugs.However,there is a risk of not delivering both the drugs to the target site together,which can be overcome by the liposomal entrapment of those drugs and at a time knock an opportunity to reduce the dosage of amphotericin B if the combination drug provides a synergistic effect with it.Therefore,this review presents a novel strategy to fight against VL by introducing dual drug-loaded liposomes. 展开更多
关键词 Visceral leishmaniasis Liposomal anti-leishmanial drug dual drug liposome
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Time-varying parameters estimation with adaptive neural network EKF for missile-dual control system
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作者 YUAN Yuqi ZHOU Di +1 位作者 LI Junlong LOU Chaofei 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第2期451-462,共12页
In this paper, a filtering method is presented to estimate time-varying parameters of a missile dual control system with tail fins and reaction jets as control variables. In this method, the long-short-term memory(LST... In this paper, a filtering method is presented to estimate time-varying parameters of a missile dual control system with tail fins and reaction jets as control variables. In this method, the long-short-term memory(LSTM) neural network is nested into the extended Kalman filter(EKF) to modify the Kalman gain such that the filtering performance is improved in the presence of large model uncertainties. To avoid the unstable network output caused by the abrupt changes of system states,an adaptive correction factor is introduced to correct the network output online. In the process of training the network, a multi-gradient descent learning mode is proposed to better fit the internal state of the system, and a rolling training is used to implement an online prediction logic. Based on the Lyapunov second method, we discuss the stability of the system, the result shows that when the training error of neural network is sufficiently small, the system is asymptotically stable. With its application to the estimation of time-varying parameters of a missile dual control system, the LSTM-EKF shows better filtering performance than the EKF and adaptive EKF(AEKF) when there exist large uncertainties in the system model. 展开更多
关键词 long-short-term memory(LSTM)neural network extended Kalman filter(EKF) rolling training time-varying parameters estimation missile dual control system
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Preliminary Reflections on the Establishment of a New Energy System for the Achievement of Dual Carbon Goals
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作者 Zhang Yuqing 《China Oil & Gas》 CAS 2024年第2期3-10,共8页
China has pledged to the world to achieve carbon peak in 10 years and carbon neutrality in 30 years.This is an extremely arduous task,as it faces numerous challenges,including high energy consumption,heavy reliance on... China has pledged to the world to achieve carbon peak in 10 years and carbon neutrality in 30 years.This is an extremely arduous task,as it faces numerous challenges,including high energy consumption,heavy reliance on coal within its energy mix,and a large base of carbon emissions that must be controlled.To this end,it is necessary to advance the new energy security strategy of“Four Revolutions,One Cooperation”to a deeper level.According to interpretations from various parties,the new energy system is preliminarily summarized to have six features:new energy structure,new system form,new industrial system,new governance system,new system and mechanism,and new regulatory method.Considering building a new energy system comprehensively,“Ten Commitments”have been proposed to help achieve the dual-carbon goals.The specific measures include:ensuring the security and stability of energy supply,accelerating the transformation to green and low-carbon energy,giving priority to energy conservation and efficiency improvement,promoting multi-energy complementation and synergistic and integrated development,enhancing the digital intelligence level in the energy industry,developing centralized and distributed energy,advancing the rural energy revolution,developing critical and core technological equipment and the comprehensive energy service industry,and promoting high-quality development of the Belt and Road Initiative. 展开更多
关键词 system dual summarized
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A semantic and emotion-based dual latent variable generation model for a dialogue system 被引量:1
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作者 Ming Yan Xingrui Lou +2 位作者 Chien Aun Chan Yan Wang Wei Jiang 《CAAI Transactions on Intelligence Technology》 SCIE EI 2023年第2期319-330,共12页
With the development of intelligent agents pursuing humanisation,artificial intelligence must consider emotion,the most basic spiritual need in human interaction.Traditional emotional dialogue systems usually use an e... With the development of intelligent agents pursuing humanisation,artificial intelligence must consider emotion,the most basic spiritual need in human interaction.Traditional emotional dialogue systems usually use an external emotional dictionary to select appropriate emotional words to add to the response or concatenate emotional tags and semantic features in the decoding step to generate appropriate responses.However,selecting emotional words from a fixed emotional dictionary may result in loss of the diversity and consistency of the response.We propose a semantic and emotion-based dual latent variable generation model(Dual-LVG)for dialogue systems,which is able to generate appropriate emotional responses without an emotional dictionary.Different from previous work,the conditional variational autoencoder(CVAE)adopts the standard transformer structure.Then,Dual-LVG regularises the CVAE latent space by introducing a dual latent space of semantics and emotion.The content diversity and emotional accuracy of the generated responses are improved by learning emotion and semantic features respectively.Moreover,the average attention mechanism is adopted to better extract semantic features at the sequence level,and the semi-supervised attention mechanism is used in the decoding step to strengthen the fusion of emotional features of the model.Experimental results show that Dual-LVG can successfully achieve the effect of generating different content by controlling emotional factors. 展开更多
关键词 conditional variational autoencoder dual latent space emotional responses latent variable generation
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A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson's disease 被引量:2
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作者 Xi Chen Yuhu Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期324-330,共7页
The dichotomized brain system is a concept that was generalized from the‘dual syndrome hypothesis’to explain the heterogeneity of cognitive impairment,in which anterior and posterior brain systems are independent bu... The dichotomized brain system is a concept that was generalized from the‘dual syndrome hypothesis’to explain the heterogeneity of cognitive impairment,in which anterior and posterior brain systems are independent but partially overlap.The dopaminergic system acts on the anterior brain and is responsible for executive function,working memory,and planning.In contrast,the cholinergic system acts on the posterior brain and is responsible for semantic fluency and visuospatial function.Evidence from dopaminergic/cholinergic imaging or functional neuroimaging has shed significant insight relating to the involvement of the cerebellum in the cognitive process of patients with Parkinson’s disease.Previous research has reported evidence that the cerebellum receives both dopaminergic and cholinergic projections.However,whether these two neurotransmitter systems are associated with cognitive function has yet to be fully elucidated.Furthermore,the precise role of the cerebellum in patients with Parkinson’s disease and cognitive impairment remains unclear.Therefore,in this review,we summarize the cerebellar dopaminergic and cholinergic projections and their relationships with cognition,as reported by previous studies,and investigated the role of the cerebellum in patients with Parkinson’s disease and cognitive impairment,as determined by functional neuroimaging.Our findings will help us to understand the role of the cerebellum in the mechanisms underlying cognitive impairment in Parkinson’s disease. 展开更多
关键词 anterior brain system CEREBELLUM CHOLINERGIC cognitive impairment DOPAMINERGIC dual syndrome hypothesis neuroimage NEUROTRANSMITTER Parkinson’s disease posterior brain system therapeutic targets
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Electron-distribution control via Pt/NC and MoC/NC dual junction:Boosted hydrogen electro-oxidation and theoretical study 被引量:1
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作者 Feng Zhou Xiaofeng Ke +8 位作者 Yihuang Chen Mei Zhao Yun Yang Youqing Dong Chao Zou Xi’an Chen Huile Jin Lijie Zhang Shun Wang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第1期513-520,I0011,共9页
The scarcity,high cost and susceptibility to CO of Platinum severely restrict its application in alkaline hydrogen oxidation reaction(HOR).Hybridizing Pt with other transition metals provides an effective strategy to ... The scarcity,high cost and susceptibility to CO of Platinum severely restrict its application in alkaline hydrogen oxidation reaction(HOR).Hybridizing Pt with other transition metals provides an effective strategy to modulate its catalytic HOR performance,but at the cost of mass activity due to the coverage of modifiers on Pt surface.Herein,we constructed dual junctions'Pt/nitrogen-doped carbon(Pt/NC)andδ-MoC/NC to modify electronic structure of Pt via interfacial electron transfer to acquire Pt-MoC@NC catalyst with electron-deficient Pt nanoparticles,simultaneously endowing it with high mass activity and durability of alkaline HOR.Moreover,the unique structure of Pt-MoC@NC endows Pt with a high COtolerance at 1,000 ppm CO/H_(2),a quality that commercial Pt-C catalyst lacks.The theoretical calculations not only confirm the diffusion of electrons from Pt/NC to Mo C/NC could occur,but also demonstrate the negative shift of Pt d-band center for the optimized binding energies of*H,*OH and CO. 展开更多
关键词 Hydrogen oxidation reaction dual junctions CO-tolerance PLATINUM
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A strategy for strengthening chaotic mixing of dual shaft eccentric mixers by changing non-Newtonian fluids kinetic energy distribution 被引量:1
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作者 Songsong Wang Tong Meng +4 位作者 Qian Zhang Changyuan Tao Yundong Wang Zequan Li Zuohua Liu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第5期122-134,共13页
Efficiently modulating the velocity distribution and flow pattern of non-Newtonian fluids is a critical challenge in the context of dual shaft eccentric mixers for process intensification,posing a significant barrier ... Efficiently modulating the velocity distribution and flow pattern of non-Newtonian fluids is a critical challenge in the context of dual shaft eccentric mixers for process intensification,posing a significant barrier for the existing technologies.Accordingly,this work reports a convenient strategy that changes the kinetic energy to controllably regulate the flow patterns from radial flow to axial flow.Results showed that the desired velocity distribution and flow patterns could be effectively obtained by varying the number and structure of baffles to change kinetic energy,and a more uniform velocity distribution,which could not be reached normally in standard baffle dual shaft mixers,was easily obtained.Furthermore,a comparative analysis of velocity and shear rate distributions is employed to elucidate the mechanism behind the generation of flow patterns in various dual-shaft eccentric mixers.Importantly,there is little difference in the power number of the laminar flow at the same Reynolds number,meaning that the baffle type has no effect on the power consumption,while the power number of both unbaffle and U-shaped baffle mixing systems decreases compared with the standard baffle mixing system in the transition flow.Finally,at the same rotational condition,the dimensionless mixing time of the U-shaped baffle mixing system is 15.3%and 7.9%shorter than that of the standard baffle and the unbaffle mixing system,respectively,which shows the advantage of the U-shaped baffle in stirring rate. 展开更多
关键词 dual shaft “U-shaped”baffle Flow pattern Mixing time Power demand
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Dual Additives for Stabilizing Li Deposition and SEI Formation in Anode-Free Li-Metal Batteries 被引量:1
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作者 Baolin Wu Chunguang Chen +4 位作者 Dmitri L.Danilov Zhiqiang Chen Ming Jiang Rüdiger-A.Eichel Peter H.L.Notten 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2024年第3期84-92,共9页
Anode-free Li-metal batteries are of significant interest to energy storage industries due to their intrinsically high energy.However,the accumulative Li dendrites and dead Li continuously consume active Li during cyc... Anode-free Li-metal batteries are of significant interest to energy storage industries due to their intrinsically high energy.However,the accumulative Li dendrites and dead Li continuously consume active Li during cycling.That results in a short lifetime and low Coulombic efficiency of anode-free Li-metal batteries.Introducing effective electrolyte additives can improve the Li deposition homogeneity and solid electrolyte interphase(SEI)stability for anode-free Li-metal batteries.Herein,we reveal that introducing dual additives,composed of LiAsF6 and fluoroethylene carbonate,into a low-cost commercial carbonate electrolyte will boost the cycle life and average Coulombic efficiency of NMC‖Cu anode-free Li-metal batteries.The NMC‖Cu anode-free Li-metal batteries with the dual additives exhibit a capacity retention of about 75%after 50 cycles,much higher than those with bare electrolytes(35%).The average Coulombic efficiency of the NMC‖Cu anode-free Li-metal batteries with additives can maintain 98.3%over 100 cycles.In contrast,the average Coulombic efficiency without additives rapidly decline to 97%after only 50 cycles.In situ Raman measurements reveal that the prepared dual additives facilitate denser and smoother Li morphology during Li deposition.The dual additives significantly suppress the Li dendrite growth,enabling stable SEI formation on anode and cathode surfaces.Our results provide a broad view of developing low-cost and high-effective functional electrolytes for high-energy and long-life anode-free Li-metal batteries. 展开更多
关键词 anode-free lithium metal battery dual additives in situ Raman Li growth SEI formation
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A dual-RPA based lateral flow strip for sensitive,on-site detection of CP4-EPSPS and Cry1Ab/Ac genes in genetically modified crops 被引量:1
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作者 Jinbin Wang Yu Wang +7 位作者 Xiuwen Hu Yifan Chen Wei Jiang Xiaofeng Liu Juan Liu Lemei Zhu Haijuan Zeng Hua Liu 《Food Science and Human Wellness》 SCIE CSCD 2024年第1期183-190,共8页
Traditional transgenic detection methods require high test conditions and struggle to be both sensitive and efficient.In this study,a one-tube dual recombinase polymerase amplification(RPA)reaction system for CP4-EPSP... Traditional transgenic detection methods require high test conditions and struggle to be both sensitive and efficient.In this study,a one-tube dual recombinase polymerase amplification(RPA)reaction system for CP4-EPSPS and Cry1Ab/Ac was proposed and combined with a lateral flow immunochromatographic assay,named“Dual-RPA-LFD”,to visualize the dual detection of genetically modified(GM)crops.In which,the herbicide tolerance gene CP4-EPSPS and the insect resistance gene Cry1Ab/Ac were selected as targets taking into account the current status of the most widespread application of insect resistance and herbicide tolerance traits and their stacked traits.Gradient diluted plasmids,transgenic standards,and actual samples were used as templates to conduct sensitivity,specificity,and practicality assays,respectively.The constructed method achieved the visual detection of plasmid at levels as low as 100 copies,demonstrating its high sensitivity.In addition,good applicability to transgenic samples was observed,with no cross-interference between two test lines and no influence from other genes.In conclusion,this strategy achieved the expected purpose of simultaneous detection of the two popular targets in GM crops within 20 min at 37°C in a rapid,equipmentfree field manner,providing a new alternative for rapid screening for transgenic assays in the field. 展开更多
关键词 Genetically modifi ed crops On-site detection Lateral fl ow test strips dual recombinase polymerase amplification (RPA)
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Estimating the Monetary Value of Hours Lost to the Nigerian Public Healthcare System When Full-Time Government Employee Doctors Engage in Dual Practice
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作者 Bartholomew S. Eze Mari Jones Imani Silver Kyaruzi 《Health》 CAS 2023年第2期215-238,共24页
Background: Dual Practice (DP) allows full-time public sector doctors to concurrently offer the same clinical services in the private sector. The debate against this practice seems to be largely influenced by its pote... Background: Dual Practice (DP) allows full-time public sector doctors to concurrently offer the same clinical services in the private sector. The debate against this practice seems to be largely influenced by its potential to reduce the contracted hours in the public sector and shift attention to private work. Purpose: The purpose of this secondary research is to estimate the monetary value of hours lost to the Nigerian public healthcare system when full-time government employee doctors are engaged in private practice. It attempts to quantify the amount of resource outflow from the public system due to absences and lateness arising from competition for time between the public system’s contracted hours and private practice. Methods: Sensitivity analysis in Excel 2010 was used to calculate doctors’ hourly pay in the public sector using the 2015 Consolidated Medical Salary Structure for medical and dental officers in Nigeria’s federal public service. The parameters used for the calculation were the official 40-hour working week and the average monthly gross pay of doctors on different grade levels. Hypothetical scenarios of hours lost due to absences associated with DP were created. The value of different hypothetical hour losses by the percentage of doctors assumed to engage in dual practice across all doctor grade levels was then computed. Results: The estimated annual value of hours lost from dual practice to a single public tertiary care hospital was N4,851,754 or 15,855 USD (best case scenario) and N19,407,017 or 63,422 USD (worst case scenario) for the normal routine work and N1,800,133 or 5883 USD (best case scenario) and N3,600,266 or 11,766 USD (worst case scenario) for the on-call duty. Conclusion: The government may have been paying salaries for large volumes of work not rendered in the public sector. The overall financial impact of dual practice in the Nigerian public system might be negative. 展开更多
关键词 dual Practice Hours Lost Nigeria Private Practice Public Healthcare Absences
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Enhanced Precision Therapy of Multiple Myeloma Through Engineered Biomimetic Nanoparticles with Dual Targeting
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作者 Ruogu Qi Shanshan Wang +8 位作者 Jiayi Yu Tianming Lu Zhiqiang Bi Weibo Liu Yuanyuan Guo Yong Bian Jianliang Shen Xuesong Zhang Wenhao Hu 《Engineering》 SCIE EI CAS CSCD 2024年第5期178-192,共15页
Multiple myeloma(MM)is the second most prevalent hematological malignancy.Current MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic efficacy.This study addressed these limitations th... Multiple myeloma(MM)is the second most prevalent hematological malignancy.Current MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic efficacy.This study addressed these limitations through the development of a potent MM-targeting chemotherapy strategy,which capitalized on the high binding affinity of alendronate for hydroxyapatite in the bone matrix and the homologous targeting of myeloma cell membranes,termed T-PB@M.The results from our investigations highlight the considerable bone affinity of T-PB@M,both in vitro and in vivo.Additionally,this material demonstrated a capability for drug release triggered by low pH conditions.Moreover,T-PB@M induced the generation of reactive oxygen species and triggered cell apoptosis through the poly(ADP-ribose)polymerase 1(PARP1)-Caspase-3-B-cell lymphoma-2(Bcl-2)pathway in MM cells.Notably,T-PB@M preferentially targeted bone-involved sites,thereby circumventing systemic toxic side effects and leading to prolonged survival of MM orthotopic mice.Therefore,this designed target-MM nanocarrier presents a promising and potentially effective platform for the precise treatment of MM. 展开更多
关键词 Multiple myeloma BORTEZOMIB Drug delivery dual targeting Controlled release
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Mg/Fe site-specific dual-doping to boost the performance of cobalt-free nickle-rich layered oxide cathode for high-energy lithium-ion batteries
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作者 Yunting Wang Gaohui Du +7 位作者 Di Han Wenhao Shi Jiahao Deng Huayu Li Wenqi Zhao Shukai Ding Qingmei Su Bingshe Xu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第4期670-679,共10页
Layer-type LiNi0.9Mn0.1O2is promising to be the primary cathode material for lithium-ion batteries(LIBs)due to its excellent electrochemical performance.Unfortunately,the cathode with high nickel content suffers from ... Layer-type LiNi0.9Mn0.1O2is promising to be the primary cathode material for lithium-ion batteries(LIBs)due to its excellent electrochemical performance.Unfortunately,the cathode with high nickel content suffers from severely detrimental structural transformation that causes rapid capacity attenuation.Herein,site-specific dual-doping with Fe and Mg ions is proposed to enhance the structural stability of LiNi0.9Mn0.1O2.The Fe3+dopants are inserted into transition metal sites(3b)and can favorably provide additional redox potential to compensate for charge and enhance the reversibility of anionic redox.The Mg ions are doped into the Li sites(3a)and serve as O_(2)^(-)-Mg^(2+)-O_(2)^(-)pillar to reinforce the electrostatic cohesion between the two adjacent transition-metal layers,which further suppress the cracking and the generation of harmful phase transitions,ultimately improving the cyclability.The theoretical calculations,including Bader charge and crystal orbital Hamilton populations(COHP)analyses,confirm that the doped Fe and Mg can form stable bonds with oxygen and the electrostatic repulsion of O_(2)^(-)-O_(2)^(-)can be effectively suppressed,which effectively mitigates oxygen anion loss at the high delithiation state.This dual-site doping strategy offers new avenues for understanding and regulating the crystalline oxygen redox and demonstrates significant potential for designing high-performance cobalt-free nickel-rich cathodes. 展开更多
关键词 Cobalt-free Layered oxide Cathode dual dopants Density functional theory calculation
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Anion storing,oxygen vacancy incorporated perovskite oxide composites for high-performance aqueous dual ion hybrid supercapacitors
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作者 Taehun Kang Puritut Nakhanivej +3 位作者 Kyung Jae Wang Yu Chen Yongchul G Chung Ho Seok Park 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第7期646-655,共10页
Dual ion storage hybrid supercapacitors(HsCs)are considered as a promising device to overcome the limited energy density of existing supercapacitors while preserving high power and long cyclability.However,the develop... Dual ion storage hybrid supercapacitors(HsCs)are considered as a promising device to overcome the limited energy density of existing supercapacitors while preserving high power and long cyclability.However,the development of high-capacity anion-storing materials,which can be paired with fast charg-ing capacitive electrodes,lags behind cation-storing counterparts.Herein,we demonstrate the surface faradaic OH-storage mechanism of anion storing perovskite oxide composites and their application in high-performance dual ion HsCs.The oxygen vacancy and nanoparticle size of the reduced LaMnO_(3)(r-LaMnO_(3))were controlled,while r-LaMnO_(3) was chemically coupled with ozonated carbon nanotubes(oCNTs)for the improved anion storing capacity and cycle performance.As taken by in-situ and ex-situ spectroscopic and computational analyses,OH-ions are inserted into the oxygen vacancies coordi-nating with octahedral Mn with the increase in the oxidation state of Mn during the charging process or vice versa.Configuring OH-storing r-LaMnO_(3)/oCNT composite with Na*storing MXene,the as-fabricated aqueous dual ion HSCs achieved the cycle performance of 73.3%over 10,000 cycles,delivering the max-imum energy and power densities of 47.5 w h kg^(-1) and 8 kw kg^(-1),respectively,far exceeding those of previously reported aqueous anion and dual ion storage cells.This research establishes a foundation for the unique anion storage mechanism of the defect engineered perovskite oxides and the advancement of dual ion hybrid energy storage devices with high energy and power densities. 展开更多
关键词 Anion storage dual ion storage Defect engineered perovskites Hybrid supercapacitors NANOCOMPOSITES
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A Sustainable Dual Cross‑Linked Cellulose Hydrogel Electrolyte for High‑Performance Zinc‑Metal Batteries
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作者 Haodong Zhang Xiaotang Gan +1 位作者 Yuyang Yan Jinping Zhou 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第6期63-75,共13页
Aqueous rechargeable Zn-metal batteries(ARZBs)are considered one of the most promising candidates for grid-scale energy storage.However,their widespread commercial application is largely plagued by three major challen... Aqueous rechargeable Zn-metal batteries(ARZBs)are considered one of the most promising candidates for grid-scale energy storage.However,their widespread commercial application is largely plagued by three major challenges:The uncontrollable Zn dendrites,notorious parasitic side reactions,and sluggish Zn^(2+) ion transfer.To address these issues,we design a sustainable dual crosslinked cellulose hydrogel electrolyte,which has excellent mechanical strength to inhibit dendrite formation,high Zn^(2+) ions binding capacity to suppress side reaction,and abundant porous structure to facilitate Zn^(2+) ions migration.Consequently,the Zn||Zn cell with the hydrogel electrolyte can cycle stably for more than 400 h under a high current density of 10 mA cm^(−2).Moreover,the hydrogel electrolyte also enables the Zn||polyaniline cell to achieve high-rate and long-term cycling performance(>2000 cycles at 2000 mA g^(−1)).Remarkably,the hydrogel electrolyte is easily accessible and biodegradable,making the ARZBs attractive in terms of scalability and sustainability. 展开更多
关键词 CELLULOSE dual cross-linked Aqueous rechargeable Zn-metal batteries Hydrogel electrolyte
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