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Dynamically triggered seismicity on a tectonic scale:A review
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作者 Chengzhi Qi Mingyang Wang +2 位作者 Gevorg Kocharyan Artem Kunitskikh Zefan Wang 《Deep Underground Science and Engineering》 2024年第1期1-24,共24页
Earthquakes triggered by dynamic disturbances have been confirmed by numerous observations and experiments.In the past several decades,earthquake triggering has attracted increasing attention of scholars in relation t... Earthquakes triggered by dynamic disturbances have been confirmed by numerous observations and experiments.In the past several decades,earthquake triggering has attracted increasing attention of scholars in relation to exploring the mechanism of earthquake triggering,earthquake prediction,and the desire to use the mechanism of earthquake triggering to reduce,prevent,or trigger earthquakes.Natural earthquakes and large‐scale explosions are the most common sources of dynamic disturbances that trigger earthquakes.In the past several decades,some models have been developed,including static,dynamic,quasi‐static,and other models.Some reviews have been published,but explosiontriggered seismicity was not included.In recent years,some new results on earthquake triggering have emerged.Therefore,this paper presents a new review to reflect the new results and include the content of explosion‐triggered earthquakes for the reference of scholars in this area.Instead of a complete review of the relevant literature,this paper primarily focuses on the main aspects of dynamic earthquake triggering on a tectonic scale and makes some suggestions on issues that need to be resolved in this area in the future. 展开更多
关键词 dynamic disturbances dynamic models problems for future research quasi‐static models static models triggered seismicity
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A Unique Modelling Strategy to Dynamically Simulate the Performance of a Lobe Pump for Industrial Applications
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作者 Deepak Kumar Kanungo Rabiranjan Murmu Harekrushna Sutar 《Advances in Chemical Engineering and Science》 CAS 2024年第2期57-73,共17页
The performance of a newly designed tri-lobe industrial lobe pump of high capacity is simulated by using commercial CFD solver Ansys Fluent. A combination of user-defined-functions and meshing strategies is employed t... The performance of a newly designed tri-lobe industrial lobe pump of high capacity is simulated by using commercial CFD solver Ansys Fluent. A combination of user-defined-functions and meshing strategies is employed to capture the rotation of the lobes. The numerical model is validated by comparing the simulated results with the literature values. The processes of suction, displacement, compression and exhaust are accurately captured in the transient simulation. The fluid pressure value remains in the range of inlet pressure value till the processes of suction and displacement are over. The instantaneous process of compression is accurately captured in the simulation. The movement of a particular working chamber is traced along the gradual degree of lobe’s rotation. At five different degrees of lobe’s rotation, pressure contour plots are reported which clearly shows the pressure values inside the working chamber. Each pressure value inside the working chamber conforms to the particular process in which the working chamber is operating. Finally, the power requirement at the shaft of rotation is estimated from the simulated values. The estimated value of power requirement is 3.61 BHP FHP whereas the same calculated theoretically is 3 BHP FHP. The discrepancy is attributed to the assumption of symmetry of blower along the thickness. 展开更多
关键词 CFD Lobe Pump Moving Dynamic Mesh Pressure Fluctuation Transient Simulation
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Generation of dynamically perfused functional vascular network system within hydrogel using3D bio-printing technology 被引量:1
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作者 Vivian K.Lee Seung-Schik Yoo +1 位作者 Peter Vincent Guohao Dai 《医用生物力学》 EI CAS CSCD 北大核心 2013年第S1期9-11,共3页
Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissu... Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissue.However,maintaining the viability of a thick tissue structure during tissue growth and maturation is challenging due to lack of adequate vascular perfusion.In a simple tissue model with 展开更多
关键词 HYDROGEL printing PERFUSION dynamically challenging VIABILITY maintaining DESIRED THICK capable
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Coherent control of negative refraction based on local-field enhancement and dynamically induced chirality
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作者 巴诺 高金伟 +2 位作者 田杏霞 吴熙 吴金辉 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第7期284-291,共8页
This paper studies the electromagnetic response of a coherently driven dense atomic ensemble to a weak probe. It finds that negative refraction with little absorption may be achieved in the presence of local-field enh... This paper studies the electromagnetic response of a coherently driven dense atomic ensemble to a weak probe. It finds that negative refraction with little absorption may be achieved in the presence of local-field enhanced interaction and dynamically induced chirality. The complex refractive index governing the probe refraction and absorption depends critically on the atomic density, the steady population distribution, the coherence dephasings, and the frequency de- tunings, and is also sensitive to the phase of the driving field because the photonic transition paths form a close loop. Thus, it can periodically tune the refractive index at a fixed frequency from negative to positive values and vice versa just by modulating the driving phase. Moreover, the optimal negative refraction is found to be near the probe magnetic resonance, which then requires the electric fields of the probe and the drive being on two-photon resonance due to the dipole synchronisation. 展开更多
关键词 negative refraction dynamically induced chirality local field enhancement electromag-netically induced transparency
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Frequency Domain Goodness of Fit Test Based Spectrum Sensing Method with Dynamically Varying Noise
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作者 Rui Gao Peihan Qi Zhenghua Zhang 《China Communications》 SCIE CSCD 2020年第12期172-179,共8页
In cognitive radio networks,spectrum sensing under circumstances of dynamically varying noise and lacking prior information is a key challenge to the conventional spectrum sensing algorithms.Since the necessary inform... In cognitive radio networks,spectrum sensing under circumstances of dynamically varying noise and lacking prior information is a key challenge to the conventional spectrum sensing algorithms.Since the necessary information is rather difficult to obtain practically,most existing spectrum sensing methods are fettered in applications.Motivated by these,in this paper,a Frequency domain Goodness of Fit Test(FGoF)based spectrum sensing method is proposed.The FGoF makes full use of underlying information in Guard-Bands and the advantages of GoF test works for any distribution.Analytical and simulated results show that the FGoF is a robust spectrum sensing method in cognitive radio with the inherent advantages of invulnerability to dynamically varying noise. 展开更多
关键词 spectrum sensing goodness of fit test dynamically varying noise noise uncertainty
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Dynamically Reconfigurable Encryption System of the AES
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作者 WANG Youren WANG Li YAO Rui ZHANG Zhai CUI Jiang 《Wuhan University Journal of Natural Sciences》 CAS 2006年第6期1569-1572,共4页
Reconfigurable computing has grown to become an important and large field of research, it offers advantages over traditional hardware and software implementations of computational algorithms. The Advanced Encryption S... Reconfigurable computing has grown to become an important and large field of research, it offers advantages over traditional hardware and software implementations of computational algorithms. The Advanced Encryption Standard (AES) algorithm is widely applied in government department and commerce. This paper analyzed the AES algorithms with different cipher keys, adopted a novel key scheduler that generated the round key real-time, proposed a dynamically reconfigurable encryption system which supported the AES algorithm with different cipher keys, and designed the architecture of the reconfigurable system. The dynamically reconfigurable AES system had been realized on FPGA. The result proves that the reconfigurable AES system is flexible, lower cost and high security level. 展开更多
关键词 dynamically reconfigurable hardware field programmable gate array (FPGA) advanced encryption standard (AES) algorithm cipher key
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DFIG Voltage Control Based on Dynamically Adjusted Control Gains
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作者 Zhiqiang Jin Can Huang 《Journal of Power and Energy Engineering》 2014年第8期45-58,共14页
The increasing penetration of wind power presents many technical challenges to power system operations. An important challenge is the need of voltage control to maintain the terminal voltage of a wind plant to make it... The increasing penetration of wind power presents many technical challenges to power system operations. An important challenge is the need of voltage control to maintain the terminal voltage of a wind plant to make it a PV bus like conventional generators with excitation control. In the previous work for controlling wind plant, especially the Doubly Fed Induction Generator (DFIG) system, the proportional-integral (PI) controllers are popularly applied. These approaches usually need to tune the PI controllers to obtain control gains as a tradeoff or compromise among various operating conditions. In this paper, a new voltage control approach based on a different philosophy is presented. In the proposed approach, the PI control gains for the DFIG system are dynamically adjusted based on the dynamic, continuous sensitivity which essentially indicates the dynamic relationship between the change of control gains and the desired output voltage. Hence, this control approach does not require any good estimation of fixed control gains because it has the self-learning mechanism via the dynamic sensitivity. This also gives the plug-and-play feature of DFIG controllers to make it promising in utility practices. Simulation results verify that the proposed approach performs as expected under various operating conditions. 展开更多
关键词 GAIN Tuning dynamically Adjusted CONTROL GAIN RENEWABLE Energy Voltage CONTROL WIND Power
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Field structure at mode Ⅲ dynamically propagating crack tip in elastic-viscoplastic materials
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作者 贾斌 王振清 李永东 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2008年第7期919-925,共7页
An elastic-viscoplastic mechanics model is used to investigate asymptotically the mode Ⅲ dynamically propagating crack tip field in elastic-viscoplastic materials. The stress and strain fields at the crack tip posses... An elastic-viscoplastic mechanics model is used to investigate asymptotically the mode Ⅲ dynamically propagating crack tip field in elastic-viscoplastic materials. The stress and strain fields at the crack tip possess the same power-law singularity under a linear-hardening condition. The singularity exponent is uniquely determined by the viscosity coefficient of the material. Numerical results indicate that the motion parameter of the crack propagating speed has little effect on the zone structure at the crack tip. The hardening coefficient dominates the structure of the crack-tip field. However, the secondary plastic zone has little influence on the field. The viscosity of the material dominates the strength of stress and strain fields at the crack tip while it does have certain influence on the crack-tip field structure. The dynamic crack-tip field degenerates into the relevant quasi-static solution when the crack moving speed is zero. The corresponding perfectly-plastic solution is recovered from the linear-hardening solution when the hardening coefficient becomes zero. 展开更多
关键词 elastic-viscoplastic materials dynamically propagating crack mode crack crack tip field zone structure
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Specification and Verification of Dynamically Reconfigurable Systems Using Dynamic Linear Hybrid Automata
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作者 Ryo Yanase Tatsunori Sakai +1 位作者 Makoto Sakai Satoshi Yamane 《Journal of Software Engineering and Applications》 2016年第9期452-478,共27页
A dynamically reconfigurable system can change its configuration during operation, and studies of such systems are being carried out in many fields. In particular, medical technology and aerospace engineering must ens... A dynamically reconfigurable system can change its configuration during operation, and studies of such systems are being carried out in many fields. In particular, medical technology and aerospace engineering must ensure system safety because any defect will have serious consequences. Model checking is a method for verifying system safety. In this paper, we propose the Dynamic Linear Hybrid Automaton (DLHA) specification language and show a method to analyze reachability for a system consisting of several DLHAs. 展开更多
关键词 Formal Method Model Checking Hybrid Automata Embedded Systems dynamically Reconfigurable Systems
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Dynamically loading IFC models on a web browser based on spatial semantic partitioning
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作者 Hong-Lei Lu Jia-Xing Wu +1 位作者 Yu-Shen Liu Wan-Qi Wang 《Visual Computing for Industry,Biomedicine,and Art》 2019年第1期26-37,共12页
Industry foundation classes(IFC)is an open and neutral data format specification for building information modeling(BIM)that plays a crucial role in facilitating interoperability.With increases in web-based BIM applica... Industry foundation classes(IFC)is an open and neutral data format specification for building information modeling(BIM)that plays a crucial role in facilitating interoperability.With increases in web-based BIM applications,there is an urgent need for fast loading large IFC models on a web browser.However,the task of fully loading large IFC models typically consumes a large amount of memory of a web browser or even crashes the browser,and this significantly limits further BIM applications.In order to address the issue,a method is proposed for dynamically loading IFC models based on spatial semantic partitioning(SSP).First,the spatial semantic structure of an input IFC model is partitioned via the extraction of story information and establishing a component space index table on the server.Subsequently,based on user interaction,only the model data that a user is interested in is transmitted,loaded,and displayed on the client.The presented method is implemented via Web Graphics Library,and this enables large IFC models to be fast loaded on the web browser without requiring any plug-ins.When compared with conventional methods that load all IFC model data for display purposes,the proposed method significantly reduces memory consumption in a web browser,thereby allowing the loading of large IFC models.When compared with the existing method of spatial partitioning for 3D data,the proposed SSP entirely uses semantic information in the IFC file itself,and thereby provides a better interactive experience for users. 展开更多
关键词 Building information modelling Industry foundation classes IFC models dynamically loading online
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Study of the structure and the mechanical properties of dynamically cured PP/MAH-g-SEBS/epoxy blends 被引量:7
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作者 Xue Liang Jiang Yin Xi Zhang 《Chinese Chemical Letters》 SCIE CAS CSCD 2009年第7期877-880,共4页
A new method concerning with the simultaneous reinforcing and toughening of polypropylene (PP) was reported. Dynamical cure of the epoxy resin was successfully applied in the PP/maleic anhydride-grafted styrene-ethy... A new method concerning with the simultaneous reinforcing and toughening of polypropylene (PP) was reported. Dynamical cure of the epoxy resin was successfully applied in the PP/maleic anhydride-grafted styrene-ethylene-butylene-styrene (SEBS) triblock copolymer, and the obtained blends named as dynamically cured PP/MAH-g-SEBS/epoxy blends. The stiffness and toughness of the blends are in a good balance, and MAH-g-SEBS was acted as not only an impact modifier but also a compatibilizer. The structure of the dynamically cured PP/MAH-g-SEBS/epoxy blends is the embedding of the epoxy particles by the MAH-g- SEBS.C2009 Xue Liang Jiang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. 展开更多
关键词 Dynamical cure Epoxy resin PP MAH-g-SEBS
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Influence of rolling parameters on dynamically recrystallized microstructures in AZ31 magnesium alloy sheets 被引量:11
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作者 Lili Guo Fumio Fujita 《Journal of Magnesium and Alloys》 SCIE EI CAS 2015年第2期95-105,共11页
Conventional rolling experiments via the embedded pin in rolling sheet method were carried out at different reduction rates,starting rolling temperatures,and rolling speeds,and the effects of rolling parameters(i.e.,t... Conventional rolling experiments via the embedded pin in rolling sheet method were carried out at different reduction rates,starting rolling temperatures,and rolling speeds,and the effects of rolling parameters(i.e.,temperature,equivalent strain,and rolling time)on dynamically recrystallized(DRX)microstructures of AZ31 alloy during hot rolling were studied quantitatively.The temperature-strain dependence of the high-angle grain boundary fraction(HAGB%)was examined through electron backscattered diffraction.Results showed that as-rolled microstructures with high HAGB%may be obtained under average rolling temperatures of 270-320℃,equivalent strains higher than 0.8,and a rolling speed of 246 mm/s.These results may be related to the DRX kinetics and dynamic recovery which are controlled by deformation temperature and strain.HAGB%decreased with increasing rolling time(decreasing rolling speed),which is attributed to dynamic recovery,and the recrystallized grain size decreased as rolling time increased.However,further increases in rolling time increased average grain sizes but decreased mean subgrain sizes;these results are attributed to increases in the low-angle grain boundary(LAGB)length per unit area with rolling time.LAGB formation was controlled by dynamic recovery,which consistently follows polygonization or formation of new subgrains inside larger grains;hence,average subgrain sizes decreased with the rolling time.The effect of dynamic recovery on HAGB and LAGB formation and their related mechanisms over a wide range of strains and temperatures were discussed in detail. 展开更多
关键词 Magnesium alloys Hot rolling Dynamic recrystallization(DRX) MICROSTRUCTURE
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Dynamically Exploring the QCD Matter at Finite Temperatures and Densities:A Short Review 被引量:6
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作者 Shanjin Wu Chun Shen Huichao Song 《Chinese Physics Letters》 SCIE CAS CSCD 2021年第8期23-31,共9页
We provide a concise review on recent theory advancements towards full-fledged(3+1)D dynamical descriptions of relativistic nuclear collisions at finite baryon density.Heavy-ion collisions at different collision energ... We provide a concise review on recent theory advancements towards full-fledged(3+1)D dynamical descriptions of relativistic nuclear collisions at finite baryon density.Heavy-ion collisions at different collision energies produce strongly coupled matter and probe the QCD phase transition at the crossover,critical point,and first-order phase transition regions.Dynamical frameworks provide a quantitative tool to extract properties of hot QCD matter and map fireballs to the QCD phase diagram.Outstanding challenges are highlighted when confronting current theoretical frameworks with current and forthcoming experimental measurements from the RHIC beam energy scan programs. 展开更多
关键词 DENSITY DYNAMICAL COLLISION
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A Polynomial Prediction Filter Method for Estimating Multisensor Dynamically Varying Biases 被引量:3
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作者 GAO Yu ZHANG Jian-qiu HU Bo 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2007年第3期240-246,共7页
The estimation of the sensor measurement biases in a multisensor system is vital for the sensor data fusion. A solution is provided for the estimation of dynamically varying multiple sensor biases without any knowledg... The estimation of the sensor measurement biases in a multisensor system is vital for the sensor data fusion. A solution is provided for the estimation of dynamically varying multiple sensor biases without any knowledge of the dynamic bias model parameters. It is shown that the sensor bias pseudomeasurement can be dynamically obtained via a parity vector. This is accomplished by multiplying the sensor uncalibrated measurement equations by a projection matrix so that the measured variable is eliminated from the equations. Once the state equations of the dynamically varying sensor biases are modeled by a polynomial prediction filter, the dynamically varying multisensor biases can be obtained by Kalman filter. Simulation results validate that the proposed method can estimate the constant biases and dynamic biases of multisensors and outperforms the methods reported in literature. 展开更多
关键词 signal processing dynamic bias estimation simulation MULTISENSOR Kalman filter
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A Concept of Dynamically Reconfigurable Real-time Vision System for Autonomous Mobile Robotics 被引量:3
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作者 Aymeric De Cabrol Thibault Garcia +1 位作者 Patrick Bonnin Maryline Chetto 《International Journal of Automation and computing》 EI 2008年第2期174-184,共11页
This paper describes specific constraints of vision systems that are dedicated to be embedded in mobile robots. If PC-based hardware architecture is convenient in this field because of its versatility, flexibility, pe... This paper describes specific constraints of vision systems that are dedicated to be embedded in mobile robots. If PC-based hardware architecture is convenient in this field because of its versatility, flexibility, performance, and cost, current real-time operating systems are not completely adapted to long processing with varying duration, and it is often necessary to oversize the system to guarantee fail-safe functioning. Also, interactions with other robotic tasks having more priority are difficult to handle. To answer this problem, we have developed a dynamically reconfigurable vision processing system, based on the innovative features of Cleopatre real-time applicative layer concerning scheduling and fault tolerance. This framework allows to define emergency and optional tasks to ensure a minimal quality of service for the other subsystems of the robot, while allowing to adapt dynamically vision processing chain to an exceptional overlasting vision process or processor overload. Thus, it allows a better cohabitation of several subsystems in a single hardware, and to develop less expensive but safe systems, as they will be designed for the regular case and not rare exceptional ones. Finally, it brings a new way to think and develop vision systems, with pairs of complementary operators. 展开更多
关键词 Real-time vision dynamic reconfiguration embedded systems ROBUSTNESS real-time operating system
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STUDY ON THE MISCIBILITY OF DYNAMICALLY VULCANIZED EPDM/PP BLEND BY POSITRON ANNIHILATION SPECTROSCOPY 被引量:2
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作者 Tao Jiang Xue-liang Jiang +3 位作者 Shi-yuan Cheng Yi-qun Dai Shao-jie Wang Bo Wang Faculty of Chemistry & Material, Hubei University, Wuhan 430062, China Department of Physics, Wuhan University, Wuhan 430072, China 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2000年第2期123-128,共6页
Positron annihilation spectroscopy (PAS) was utilized to investigate the relationship between the free-volume hole properties and miscibility of dynamically vulcanized EPDM/PP blend. The results showed that the noncry... Positron annihilation spectroscopy (PAS) was utilized to investigate the relationship between the free-volume hole properties and miscibility of dynamically vulcanized EPDM/PP blend. The results showed that the noncrystalline region of PP and EPDM in the blend was partially miscible and the miscibility of the blend became worse when the weight percent of EPDM was <50%. This was also demonstrated by DMTA and mechanical properties of the blends with various compositions. 展开更多
关键词 EPDM PP dynamic vulcanization MISCIBILITY PAS
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Free-Fall Penetration Behaviors of A New Dynamically Installed Plate Anchor in Marine Clay 被引量:1
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作者 LAI Ying HUANG Yun-han +1 位作者 CHEN Chuan ZHU Bin 《China Ocean Engineering》 SCIE EI CSCD 2020年第6期795-805,共11页
A new dynamically installed plate anchor, the Flying Wing Anchor~?, has been developed as a sustainable anchor concept for deep-water offshore wind turbines. The anchor is firstly installed by free-fall penetration an... A new dynamically installed plate anchor, the Flying Wing Anchor~?, has been developed as a sustainable anchor concept for deep-water offshore wind turbines. The anchor is firstly installed by free-fall penetration and then followed by drag embedment. If the anchor is subjected to environmental loads, it dives deeper to mobilize a higher capacity. This study presents a series of free-fall penetration tests with model anchors in different weights to assess the anchor behavior during the free-fall penetration performance in one-layer soil with a constant shear strength profile. Anchor velocities and embedment depths were measured by a magnetometer. An energy-based model and a force-based model were calibrated against the test results of model anchors with different weights. Based on the calibrated force-based model, a series of design charts were developed to estimate the embedment depth of anchors in different sizes and with different impact velocities in various marine clays. The framework to plot design charts presented herein can be potentially applied to other dynamically installed anchors to predict embedment depth in engineering practice. 展开更多
关键词 dynamic anchor dynamic installation plate anchor scale effect design chart
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On the dynamically formed oxide films in molten Mg 被引量:1
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作者 Mohammad Mahdi Jalilvand Mehdi Akbarifar +1 位作者 Mehdi Divandari Hassan Saghafian 《Journal of Magnesium and Alloys》 SCIE 2020年第1期219-230,共12页
The so-called“Oxide/Metal/Oxide sandwich”method is one of the technique used to investigate the dynamic oxidation of metals which happens during the casting process.In this study,characteristics of the oxide films f... The so-called“Oxide/Metal/Oxide sandwich”method is one of the technique used to investigate the dynamic oxidation of metals which happens during the casting process.In this study,characteristics of the oxide films formed on the molten magnesium in dynamic conditions have been investigated using the aforementioned method.The air bubbles were released into the cast sample at the pressure of 0.2 atm through a quartz tube of 1 mm internal diameter.The interface of two adjacent entrapped bubbles is considered as the Oxide/Metal/Oxide(OMO)sandwich.The sandwiches were characterized by the aid of the optical and scanning electron microscopy and also X-Ray diffraction analyses.Two different approaches,including measuring the width of the folds formed on the oxide films and the edge of the sandwiches,were used to estimate the thickness of the films.The thicknesses were estimated to be in the range of 200 to 800 nm.The features such as fold,wrinkle,and crack were observed on the OMO sandwiches.On the microscopic scale,the oxide films were rough and porous.This is attributed to the non-protective behavior of oxide films.The XRD patterns indicated that the oxide films formed on the pure molten magnesium in dynamic conditions are crystallized MgO. 展开更多
关键词 Dynamic oxidation Bifilm MAGNESIUM Oxide films Casting defects
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Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides 被引量:1
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作者 Femke Mathot Nadia Rbia +4 位作者 Roman Thaler Allan B.Dietz Andre Jvan Wijnen Allen T.Bishop Alexander Y.Shin 《Neural Regeneration Research》 SCIE CAS CSCD 2021年第8期1613-1621,共9页
It was hypothesized that mesenchymal stem cells(MSCs) could provide necessary trophic factors when seeded onto the surfaces of commonly used nerve graft substitutes. We aimed to determine the gene expression of MSCs w... It was hypothesized that mesenchymal stem cells(MSCs) could provide necessary trophic factors when seeded onto the surfaces of commonly used nerve graft substitutes. We aimed to determine the gene expression of MSCs when influenced by Avance■ Nerve Grafts or Neura Gen■ Nerve Guides. Human adipose-derived MSCs were cultured and dynamically seeded onto 30 Avance■ Nerve Grafts and 30 Neura Gen■ Nerve Guides for 12 hours. At six time points after seeding, quantitative polymerase chain reaction analyses were performed for five samples per group. Neurotrophic [nerve growth factor(NGF), glial cell line-derived neurotrophic factor(GDNF), pleiotrophin(PTN), growth associated protein 43(GAP43) and brain-derived neurotrophic factor(BDNF)], myelination [peripheral myelin protein 22(PMP22) and myelin protein zero(MPZ)], angiogenic [platelet endothelial cell adhesion molecule 1(PECAM1/CD31) and vascular endothelial cell growth factor alpha(VEGFA)], extracellular matrix(ECM) [collagen type alpha I(COL1A1), collagen type alpha III(COL3A1), Fibulin 1(FBLN1) and laminin subunit beta 2(LAMB2)] and cell surface marker cluster of differentiation 96(CD96) gene expression was quantified. Unseeded Avance■ Nerve Grafts and Neura Gen■ Nerve Guides were used to evaluate the baseline gene expression, and unseeded MSCs provided the baseline gene expression of MSCs. The interaction of MSCs with the Avance■ Nerve Grafts led to a short-term upregulation of neurotrophic(NGF, GDNF and BDNF), myelination(PMP22 and MPZ) and angiogenic genes(CD31 and VEGFA) and a long-term upregulation of BDNF, VEGFA and COL1A1. The interaction between MSCs and the Neura Gen■ Nerve Guide led to short term upregulation of neurotrophic(NGF, GDNF and BDNF) myelination(PMP22 and MPZ), angiogenic(CD31 and VEGFA), ECM(COL1A1) and cell surface(CD96) genes and long-term upregulation of neurotrophic(GDNF and BDNF), angiogenic(CD31 and VEGFA), ECM genes(COL1A1, COL3A1, and FBLN1) and cell surface(CD96) genes. Analysis demonstrated MSCs seeded onto Neura Gen■ Nerve Guides expressed significantly higher levels of neurotrophic(PTN), angiogenic(VEGFA) and ECM(COL3A1, FBLN1) genes in the long term period compared to MSCs seeded onto Avance■ Nerve Grafts. Overall, the interaction between human MSCs and both nerve graft substitutes resulted in a significant upregulation of the expression of numerous genes important for nerve regeneration over time. The in vitro interaction of MSCs with the Neura Gen■ Nerve Guide was more pronounced, particularly in the long term period(> 14 days after seeding). These results suggest that MSC-seeding has potential to be applied in a clinical setting, which needs to be confirmed in future in vitro and in vivo research. 展开更多
关键词 Avance■Nerve Grafts dynamic seeding mesenchymal stem cell NeuraGen■Nerve Guides peripheral nerve repair qPCR
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A Model with Traffic Routers, Dynamically Managing Signal Phases to Address Traffic Congestion in Real Time 被引量:1
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作者 Rajendra S. Parmar Bhushan Trivedi Aleksandar Stevanovic 《Journal of Transportation Technologies》 2018年第1期75-90,共16页
On-road Vehicular traffic congestion has detrimental effect on three lifelines: Economy, Productivity and Pollution (EPP). With ever increasing population of vehicles on road, traffic congestion is a major challenge t... On-road Vehicular traffic congestion has detrimental effect on three lifelines: Economy, Productivity and Pollution (EPP). With ever increasing population of vehicles on road, traffic congestion is a major challenge to the economy, productivity and pollution, notwithstanding continuous developments in alternative fuels, alternative sources of energy. The research develops accurate and precise model in real time which computes congestion detection, dynamic signaling algorithm to evenly distribute vehicle densities while ensuring avoidance of starvation and deadlock situation. The model incorporates road segment length and breadth, quality and achievable average speed to compute road capacity. Vehicles installed with GPS enabled devices provide their location, which enables computing road occupancy. Road occupancy is evaluated based on number of vehicles as well as area occupied by vehicles. Ratio of road occupancy and road capacity provides congestion index important to compute signal phases. The algorithm ensures every direction is serviced once during a signaling cycle ensuring no starvation. Secondly, the definition of minimum and maximum signal timings ensures against dead lock situation. A simulator is developed to validate the proposition and proves it can ease congestion by more than 50% which is better than any of the contemporary approaches offering 15% improvement. In case of higher congestion index, alternate routes are suggested based on evaluation of traffic density graphs for shortest route or knowledge database. The algorithm to compute shortest route is optimized drastically, reducing computation cost to 3*√2N vis-à-vis computation cost of N2 by classical algorithms. The proposal brings down the cost of implementation per traffic junction from USD 30,000 to USD 2000. 展开更多
关键词 Dynamic TRAFFIC Assignment INTELLIGENT Transportation Systems INTELLIGENT Vehicles ROAD TRAFFIC Control ROAD TRAFFIC Sensing TRAFFIC Management VEHICLE DETECTION VEHICLE Routing TRAFFIC Signals Vehicular CONGESTION DETECTION System Vehicular TRAFFIC VEHICLE Mobility Sensors
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