Objective: Investigate the curative effect of acupuncture on dysphasia in hypophrenia children. Methods:One hundred and sixty children with hypophrenia and dysphasia were randomly divided into an acupuncture group o...Objective: Investigate the curative effect of acupuncture on dysphasia in hypophrenia children. Methods:One hundred and sixty children with hypophrenia and dysphasia were randomly divided into an acupuncture group of 80 cases, a language training group of 40 cases and a composite group of 40 cases for clinical observation. Total intelligence quotient (TIQ), vocal intelligence quotient (VIQ) and practical intelligence quotient (PIQ) were compared between pretreatment and posttreatment in the children themselves and between the groups before and after treatment. Results. The total efficacy rate was 77.5% in the acupuncture group, 82. 5% in the composite group and 52.5% in the language training group. Conclusion. Acupuncture significantly raises TIQ, VIQ and PIQ in the sick children. Language training only raises VIQ to some degree. Acupuncture in cooperation with language training is an effective way to treat this disease.展开更多
目的对鼻咽癌放疗后吞咽障碍患者分别实施Shaker训练和下颏抗阻力(chin tuck against resistance,CTAR)训练,分析三种训练对患者的影响。方法选择2017年2月—2019年2月厦门大学附属第一医院收治的84例鼻咽癌内镜手术后化疗患者为研究对...目的对鼻咽癌放疗后吞咽障碍患者分别实施Shaker训练和下颏抗阻力(chin tuck against resistance,CTAR)训练,分析三种训练对患者的影响。方法选择2017年2月—2019年2月厦门大学附属第一医院收治的84例鼻咽癌内镜手术后化疗患者为研究对象,按随机数字表法将患者分为对照组、Shaker组以及CTAR练组,每组各28例。三组均进行常规吞咽训练,Shaker组联合Shaker训练,CTAR组联合CTAR训练。分析三组患者吞咽能力、日常生活质量、康复治疗效果以及并发症情况。结果干预前三组患者电视透视检查(video fluoroscopy swallowing study,VFSS)评级、功能性经口摄食量表(functional oral intake scale,FOIS)评级以及吞咽障碍特异性生活质量量表(swallowing-quality of life,SWAL-QOL)评分比较,差异无统计学意义(P>0.05)。干预后Shaker组和CTAR组患者VFSS评分低于对照组,FOIS和SWAL-QOL评分高于对照组,差异有统计学意义(P<0.05)。Shaker组和CTAR组之间各评分比较,差异无统计学意义(P>0.05)。对照组患者治疗总有效率为71.43%,Shaker组患者治疗总有效率为92.86%,CTAR组患者治疗总有效率为96.43%。对照组的治疗有效率明显低于Shaker组和CTAR组,差异有统计学意义(P<0.05)。Shaker组和CTAR组治疗总有效率比较,差异无统计学意义(P>0.05)。对照组、Shaker组以及CTAR组并发症发生率分别为32.14%、7.14%以及3.57%。对照组明显高于Shaker组和CTAR组,差异有统计学意义(P<0.05);Shaker组与CTAR组比较,差异无统计学意义(P>0.05)。结论Shaker和CTAR训练均能有效缓解鼻咽癌放疗后患者的吞咽障碍症状,提高摄食功能,并发症较少,改善患者预后。展开更多
目的:探讨关节镜治疗轻度成人髋臼发育不良(developmental dysphasia of the hip,DDH)的可行性和临床疗效。方法:回顾性研究于2011年5月~2014年7月在我科因DDH行关节镜手术治疗并最终获得随访的27例患者。平均年龄39.6±10.1岁(21~5...目的:探讨关节镜治疗轻度成人髋臼发育不良(developmental dysphasia of the hip,DDH)的可行性和临床疗效。方法:回顾性研究于2011年5月~2014年7月在我科因DDH行关节镜手术治疗并最终获得随访的27例患者。平均年龄39.6±10.1岁(21~59岁);男2例,女25例;左髋11例,右髋16例。本组仅收集符合Perner分型Ⅰ度,即轻度髋臼发育不良的患者,测量每位患者的外侧中心边缘角(LCE角)和股骨头覆盖率。手术在髋关节镜下进行,主要操作包括髋臼盂唇损伤的修整或缝合,髋臼或股骨头软骨损伤的清理。应用改良的髋关节Harris评分对术后疗效进行评价,同时对患者进行满意度评估。结果:27例患者从起病到手术时间为4个月到10年,平均21.6±32.3个月。随访时间33.2±9.6个月(21~53个月)。LCE角为19.8°±6.2°(13.1°~27.7°),股骨头覆盖率为67.4%±6.1%(57.4%~75.0%)。手术中证实,27例患者均存在盂唇损伤,9例行盂唇缝合术,18例行盂唇修整术;8例髋臼和股骨头软骨均无损伤,19例髋关节负重区的股骨头或/和髋臼软骨损伤,行软骨病灶清理术。Harris评分由术前的66.9±12.2分(45~90分)增加到术后的90.1±5.1分(86~100分),P<0.001。患者满意度评估中,21例(77.8%)非常满意,4例(14.8%)满意,2例(7.4%)一般。结论:髋关节镜下治疗轻度成人髋臼发育不良可以显著改善患者的髋关节症状和功能,减缓髋关节骨关节病进展,是一项安全、有效、微创的技术。展开更多
The minimal invasiveness of endoscopic submucosal dissection(ESD) prompted us to apply this technique to large-size early esophageal squamous cell carcinoma and Barrett's adenocarcinoma, despite the limitationsin ...The minimal invasiveness of endoscopic submucosal dissection(ESD) prompted us to apply this technique to large-size early esophageal squamous cell carcinoma and Barrett's adenocarcinoma, despite the limitationsin the study population and surveillance duration. A post-ESD ulceration of greater than three-fourths of esophageal circumference was advocated as an important risk factor for refractory strictures that require several sessions of dilation therapy. Most of the preoperative conditions are asymptomatic, but dilatation treatment for dysphagia associated with the stricture has potential risks of severe complications and a worsening of quality of life. Possible mechanisms of dysphasia were demonstrated based on dysmotility and pathological abnormalities at the site:(1) delayed mucosal healing;(2) severe inflammation and disorganized fibrosis with abundant extracellular matrices in the submucosa; and(3) atrophy in the muscularis proper. However, reports on the administration of anti-scarring agents, preventive dilation therapies, and regenerative medicine demonstrated limited success in stricture prevention, and there were discrepancies in the study designs and protocols of these reports. The development and consequent long-term assessments of new prophylactic technologies on the promotion of wound healing and control of the inflammatory/tumor microenvironment will require collaboration among various research fields because of the limited accuracy of preoperative staging and high-risk of local recurrence.展开更多
文摘Objective: Investigate the curative effect of acupuncture on dysphasia in hypophrenia children. Methods:One hundred and sixty children with hypophrenia and dysphasia were randomly divided into an acupuncture group of 80 cases, a language training group of 40 cases and a composite group of 40 cases for clinical observation. Total intelligence quotient (TIQ), vocal intelligence quotient (VIQ) and practical intelligence quotient (PIQ) were compared between pretreatment and posttreatment in the children themselves and between the groups before and after treatment. Results. The total efficacy rate was 77.5% in the acupuncture group, 82. 5% in the composite group and 52.5% in the language training group. Conclusion. Acupuncture significantly raises TIQ, VIQ and PIQ in the sick children. Language training only raises VIQ to some degree. Acupuncture in cooperation with language training is an effective way to treat this disease.
文摘【目的】评价醒脑开窍针刺法治疗脑卒中后吞咽困难的疗效。【方法】计算机检索中文数据库如中国生物医学文献数据库(CBM)、中国学术文献网络出版总库(CNKI)、中文科技期刊数据库(维普VIP)和万方数据库(Wanfang Data),及外文数据库如Pub Med、Web of Science、EMbase、The Cochrane Library等(从数据库建库到2014年12月)有关醒脑开窍针刺法治疗脑卒中后吞咽困难的随机对照试验(RCT)的文献。由2位评价员按纳入和排除标准独立筛选文献、提取资料和评价纳入研究的方法学质量后,采用Rev Man 5.3.0进行Meta分析。【结果】共纳入8个RCT,涉及766例患者。Meta分析显示:(1)对于恢复期患者,疗程4周的醒脑开窍针刺法联合常规治疗(内科常规治疗或内科常规治疗+吞咽功能训练)总有效率高于不联合治疗组(P<0.01);(2)对于急性期患者,疗程4周的醒脑开窍针刺法联合内科常规治疗与不联合治疗的总有效率无差别(P=0.05);(3)联合醒脑开窍针刺法对肺部并发症作用尚不确定。【结论】醒脑开窍针刺法联合常规治疗(吞咽功能训练、内科治疗)有利于脑卒中恢复期患者的吞咽功能恢复。对于脑卒中后吞咽困难的治疗时机、疗程、并发症等的疗效评估等仍然需要设计合理、报告规范的大规模、高质量的随机对照试验的验证。
文摘目的:探讨关节镜治疗轻度成人髋臼发育不良(developmental dysphasia of the hip,DDH)的可行性和临床疗效。方法:回顾性研究于2011年5月~2014年7月在我科因DDH行关节镜手术治疗并最终获得随访的27例患者。平均年龄39.6±10.1岁(21~59岁);男2例,女25例;左髋11例,右髋16例。本组仅收集符合Perner分型Ⅰ度,即轻度髋臼发育不良的患者,测量每位患者的外侧中心边缘角(LCE角)和股骨头覆盖率。手术在髋关节镜下进行,主要操作包括髋臼盂唇损伤的修整或缝合,髋臼或股骨头软骨损伤的清理。应用改良的髋关节Harris评分对术后疗效进行评价,同时对患者进行满意度评估。结果:27例患者从起病到手术时间为4个月到10年,平均21.6±32.3个月。随访时间33.2±9.6个月(21~53个月)。LCE角为19.8°±6.2°(13.1°~27.7°),股骨头覆盖率为67.4%±6.1%(57.4%~75.0%)。手术中证实,27例患者均存在盂唇损伤,9例行盂唇缝合术,18例行盂唇修整术;8例髋臼和股骨头软骨均无损伤,19例髋关节负重区的股骨头或/和髋臼软骨损伤,行软骨病灶清理术。Harris评分由术前的66.9±12.2分(45~90分)增加到术后的90.1±5.1分(86~100分),P<0.001。患者满意度评估中,21例(77.8%)非常满意,4例(14.8%)满意,2例(7.4%)一般。结论:髋关节镜下治疗轻度成人髋臼发育不良可以显著改善患者的髋关节症状和功能,减缓髋关节骨关节病进展,是一项安全、有效、微创的技术。
文摘The minimal invasiveness of endoscopic submucosal dissection(ESD) prompted us to apply this technique to large-size early esophageal squamous cell carcinoma and Barrett's adenocarcinoma, despite the limitationsin the study population and surveillance duration. A post-ESD ulceration of greater than three-fourths of esophageal circumference was advocated as an important risk factor for refractory strictures that require several sessions of dilation therapy. Most of the preoperative conditions are asymptomatic, but dilatation treatment for dysphagia associated with the stricture has potential risks of severe complications and a worsening of quality of life. Possible mechanisms of dysphasia were demonstrated based on dysmotility and pathological abnormalities at the site:(1) delayed mucosal healing;(2) severe inflammation and disorganized fibrosis with abundant extracellular matrices in the submucosa; and(3) atrophy in the muscularis proper. However, reports on the administration of anti-scarring agents, preventive dilation therapies, and regenerative medicine demonstrated limited success in stricture prevention, and there were discrepancies in the study designs and protocols of these reports. The development and consequent long-term assessments of new prophylactic technologies on the promotion of wound healing and control of the inflammatory/tumor microenvironment will require collaboration among various research fields because of the limited accuracy of preoperative staging and high-risk of local recurrence.