The basic conditions of the enterprise informatization in Heilongjiang province are analyzed and 4 models are designed to drive the industrial and commercial information enterprise. The 4 models are the Resource Integ...The basic conditions of the enterprise informatization in Heilongjiang province are analyzed and 4 models are designed to drive the industrial and commercial information enterprise. The 4 models are the Resource Integration Informatization Model, the Flow Management Informatization Model, the Intranet E-commerce Informatization Model and the Network Enterprise Informatization Model. The conditions for using and problems needing attentions of these 4 models are also analyzed.展开更多
In the past decade,the e-government affairs keep developing,which prom otes the reform of governmental affairs and the enhancement of administrative efficiency.However,the phenomenon of inform ation silo has bad influ...In the past decade,the e-government affairs keep developing,which prom otes the reform of governmental affairs and the enhancement of administrative efficiency.However,the phenomenon of inform ation silo has bad influence upon the governm ental information resources sharing and the efficiency of the e-government affairs,hindering inform ation connectivity,so that the government management cannot meet the need of society,nor can the e-governm ent develop in the long run.This paper attempts to analyze the embodiment and causes of the phenomenon of information silo,putting forward measures of solving the problem of inform ation silo.展开更多
Escherichia coli is a model organism with a clear genetic background that is widely used in metabolic engineering and synthetic biology research.To gain a complete picture of the complexly metabolic and regulatory int...Escherichia coli is a model organism with a clear genetic background that is widely used in metabolic engineering and synthetic biology research.To gain a complete picture of the complexly metabolic and regulatory interactions in E.coli,researchers often need to retrieve information from various databases which cover diferent types of interactions.A central one-stop service integrating various molecular interactions in E.coli would be helpful for the community.We constructed a database called E.coli integrated network(EcoIN)by integrating known molecular interaction information from databases and literature.EcoIN contains nearly 160,000 pairs of interactions and users can easily search the diferent types of interacting partners for a metabolite,gene or protein,and thus gain access to a more comprehensive interaction map of E.coli.To illustrate the application of EcoIN,we used the full path algorithm to identify metabolic feedback/feedforward regulatory loops having at least two diferent types of regulatory interactions.Applying this algorithm to analyze the regulatory loops for the amino acid biosynthetic pathways,we found some multi-step regulation loops which may afect the metabolic fux and are potential new engineering targets.The EcoIN database is freely accessible at http://ecoin.ibiodesign.net/and analysis codes are available at GitHub:https://github.com/maozhitao/EcoIN.展开更多
文摘The basic conditions of the enterprise informatization in Heilongjiang province are analyzed and 4 models are designed to drive the industrial and commercial information enterprise. The 4 models are the Resource Integration Informatization Model, the Flow Management Informatization Model, the Intranet E-commerce Informatization Model and the Network Enterprise Informatization Model. The conditions for using and problems needing attentions of these 4 models are also analyzed.
文摘In the past decade,the e-government affairs keep developing,which prom otes the reform of governmental affairs and the enhancement of administrative efficiency.However,the phenomenon of inform ation silo has bad influence upon the governm ental information resources sharing and the efficiency of the e-government affairs,hindering inform ation connectivity,so that the government management cannot meet the need of society,nor can the e-governm ent develop in the long run.This paper attempts to analyze the embodiment and causes of the phenomenon of information silo,putting forward measures of solving the problem of inform ation silo.
基金Publication costs are funded by the National Key Research and Development Program of China(2018YFA0900300,2018YFA0901400)the International Partnership Program of Chinese Academy of Sciences(153D31KYSB20170121)Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIPPTJS-001,TSBICIP-KJGG-005).
文摘Escherichia coli is a model organism with a clear genetic background that is widely used in metabolic engineering and synthetic biology research.To gain a complete picture of the complexly metabolic and regulatory interactions in E.coli,researchers often need to retrieve information from various databases which cover diferent types of interactions.A central one-stop service integrating various molecular interactions in E.coli would be helpful for the community.We constructed a database called E.coli integrated network(EcoIN)by integrating known molecular interaction information from databases and literature.EcoIN contains nearly 160,000 pairs of interactions and users can easily search the diferent types of interacting partners for a metabolite,gene or protein,and thus gain access to a more comprehensive interaction map of E.coli.To illustrate the application of EcoIN,we used the full path algorithm to identify metabolic feedback/feedforward regulatory loops having at least two diferent types of regulatory interactions.Applying this algorithm to analyze the regulatory loops for the amino acid biosynthetic pathways,we found some multi-step regulation loops which may afect the metabolic fux and are potential new engineering targets.The EcoIN database is freely accessible at http://ecoin.ibiodesign.net/and analysis codes are available at GitHub:https://github.com/maozhitao/EcoIN.
