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Metallurgical performance evaluation of space-weathered Chang’e-5 lunar soil
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作者 Chen Li Wenhui Ma +1 位作者 Yang Li Kuixian Wei 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第6期1241-1248,共8页
Space metallurgy is an interdisciplinary field that combines planetary space science and metallurgical engineering.It involves systematic and theoretical engineering technology for utilizing planetary resources in sit... Space metallurgy is an interdisciplinary field that combines planetary space science and metallurgical engineering.It involves systematic and theoretical engineering technology for utilizing planetary resources in situ.However,space metallurgy on the Moon is challenging because the lunar surface has experienced space weathering due to the lack of atmosphere and magnetic field,making the mi-crostructure of lunar soil differ from that of minerals on the Earth.In this study,scanning electron microscopy and transmission electron microscopy analyses were performed on Chang’e-5 powder lunar soil samples.The microstructural characteristics of the lunar soil may drastically change its metallurgical performance.The main special structure of lunar soil minerals include the nanophase iron formed by the impact of micrometeorites,the amorphous layer caused by solar wind injection,and radiation tracks modified by high-energy particle rays inside mineral crystals.The nanophase iron presents a wide distribution,which may have a great impact on the electromagnetic prop-erties of lunar soil.Hydrogen ions injected by solar wind may promote the hydrogen reduction process.The widely distributed amorph-ous layer and impact glass can promote the melting and diffusion process of lunar soil.Therefore,although high-energy events on the lun-ar surface transform the lunar soil,they also increase the chemical activity of the lunar soil.This is a property that earth samples and tradi-tional simulated lunar soil lack.The application of space metallurgy requires comprehensive consideration of the unique physical and chemical properties of lunar soil. 展开更多
关键词 space metallurgy Chang’e-5 lunar soil space weathering metallurgical performance
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血清ESM-1、E-cad对ACI-LAA溶栓后HT的预测价值
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作者 茹姗 邹婷 +2 位作者 杜磊 韩登峰 马建华 《脑与神经疾病杂志》 CAS 2024年第2期96-99,共4页
目的 探讨血清内皮细胞特异性分子-1 (ESM-1)、E-钙黏连蛋白(E-cad)对大动脉粥样硬化型脑梗死(ACI-LAA)溶栓后出血转化(HT)的预测价值。方法 选取2020年1月至2022年12月新疆医科大学第一附属医院收治的110例ACI-LAA患者,根据是否发生HT... 目的 探讨血清内皮细胞特异性分子-1 (ESM-1)、E-钙黏连蛋白(E-cad)对大动脉粥样硬化型脑梗死(ACI-LAA)溶栓后出血转化(HT)的预测价值。方法 选取2020年1月至2022年12月新疆医科大学第一附属医院收治的110例ACI-LAA患者,根据是否发生HT分为HT组和non-HT组。对比两组基础资料及血清ESM-1、E-cad水平。采用ROC曲线分析ESM-1、E-cad预测ACI-LAA患者发生HT的价值。结果 HT组患者NIHSS评分高于non-HT组,梗死面积大于non-HT组(P <0.05),HT组患者血清ESM-1、E-cad水平也高于non-HT组(P<0.05)。Logistic回归分析显示,梗死面积大、NIHSS评分高、血清ESM-1和E-cad水平升高是ACI-LAA患者发生HT的危险因素(P<0.05)。ESM-1联合E-cad预测ACI-LAA患者发生HT的曲线下面积为0.859,预测灵敏度为84.6%,特异度为72.6%。结论 血清ESM-1和E-cad水平与ACI-LAA患者HT密切相关,可作为早期预测发生HT的参考指标。 展开更多
关键词 动脉粥样硬化 脑梗死 出血转化 内皮细胞特异性分子-1 e-钙黏连蛋白
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miR-200c/ZEB1/E-cadherin轴在胆管癌转移侵袭中的作用及对胆管癌预后评估的价值
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作者 潘超 许蔚 +2 位作者 刘子君 陶平 杨士勇 《现代肿瘤医学》 CAS 2024年第7期1287-1294,共8页
目的:探讨微小RNA-200c(miR-200c)/锌指转录因子(ZEB1)/E-钙黏蛋白(E-cadherin)在胆管癌(HCCA)转移、侵袭中的作用及对HCCA预后评估的临床价值。方法:选取2020年08月至2022年12月间我院收治的胆管癌患者36例为研究对象,同时选取胆管良... 目的:探讨微小RNA-200c(miR-200c)/锌指转录因子(ZEB1)/E-钙黏蛋白(E-cadherin)在胆管癌(HCCA)转移、侵袭中的作用及对HCCA预后评估的临床价值。方法:选取2020年08月至2022年12月间我院收治的胆管癌患者36例为研究对象,同时选取胆管良性疾病患者(胆总管结石或胆管良性狭窄)20例作为对照。采用原位杂交、实时荧光定量PCR检测miR-200c在HCCA患者组织及血清中的表达;生存曲线分析miR-200c表达与总生存期的相关性;Transwell实验检测细胞的迁移及侵袭能力;免疫印迹检测ZEB1及E-cadherin蛋白的表达。体内研究构建裸鼠成瘤实验,采用免疫组化检测ZEB1及E-cadherin蛋白的表达;Tunel技术检测组织中的凋亡情况。受试者工作特征(ROC)曲线评估生物标志物对胆管癌预后的诊断效能。结果:miR-200c低表达于HCCA组织及血清中;生存曲线分析显示,miR-200c表达与患者的总生存期呈正相关性,TNM分期与患者的总生存期呈负相关性;miR-200c mimics抑制了胆管癌细胞的迁移和侵袭能力,并降低ZEB1表达而诱导E-cadherin表达;转染ZEB1逆转miR-200c的作用效应,促进胆管癌细胞的迁移和侵袭特性,抑制胆管癌细胞的凋亡。CA199、CEA和miR-200c联合检测诊断胆管癌预后的ROC曲线下面积为0.892,灵敏度0.8611,特异度0.8000。结论:miR-200c/ZEB1/Ecadherin轴参与胆管癌的转移侵袭;CA199、CEA和miR-200c联合检测对胆管癌预后的诊断效能良好,对临床胆管癌的治疗策略具有重要指导价值。 展开更多
关键词 胆管癌 微小RNA-200c(miR-200c) 锌指转录因子(ZEB1) e-钙黏蛋白(e-cadherin) 迁移 侵袭
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中药砒霜上调E-钙黏蛋白抑制宫颈癌Hela细胞生长、侵袭、迁移机制研究
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作者 李思瑾 李海盈 +3 位作者 何泽阳 李安 张亚文 李道成 《新中医》 CAS 2024年第14期145-152,共8页
目的:研究中药砒霜的主要成分三氧化二砷(As_(2)O_(3))抑制宫颈癌Hela细胞生长、侵袭、迁移的机制,观察As_(2)O_(3)对宫颈癌Hela细胞组蛋白脱乙酰基酶1(HDAC1)、E-钙黏蛋白表达的影响,以及联合HDAC1抑制剂伏立诺他(SAHA)的协同作用。方... 目的:研究中药砒霜的主要成分三氧化二砷(As_(2)O_(3))抑制宫颈癌Hela细胞生长、侵袭、迁移的机制,观察As_(2)O_(3)对宫颈癌Hela细胞组蛋白脱乙酰基酶1(HDAC1)、E-钙黏蛋白表达的影响,以及联合HDAC1抑制剂伏立诺他(SAHA)的协同作用。方法:以宫颈癌Hela细胞作为载体,随机分为空白对照组、As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组4组,采用CCK-8法测定不同药物浓度对Hela细胞活性的抑制情况,并筛选后续实验药物浓度;采用Transwell法、划痕法检测各组药物对Hela细胞侵袭、迁移能力的影响;采用实时荧光定量聚合酶链式反应及蛋白免疫印迹法检测HDAC1和E-钙黏蛋白的mRNA表达情况与蛋白表达情况。结果:随着各组药物浓度增加,Hela细胞的活性逐渐降低。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组的Hela细胞活性均低于空白对照组(P<0.05)。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组穿越Transwell小室膜的细胞数量均少于空白对照组(P<0.05);As_(2)O_(3)+SAHA组的细胞数量少于As_(2)O_(3)组、SAHA组(P<0.05);As_(2)O_(3)组的细胞数量少于SAHA组(P<0.05)。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组的Hela细胞迁移百分比均低于空白对照组(P<0.05);As_(2)O_(3)+SAHA组的Hela细胞迁移百分比低于As_(2)O_(3)组、SAHA组(P<0.05);As_(2)O_(3)组的Hela细胞迁移百分比低于SAHA组(P<0.05)。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组的HDAC1 mRNA表达水平均低于空白对照组(P<0.05);As_(2)O_(3)组的HDAC1 mRNA表达水平高于SAHA组(P<0.05);As_(2)O_(3)+SAHA组的HDAC1 mRNA表达水平低于As_(2)O_(3)组、SAHA组(P<0.05)。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组的E-钙黏蛋白mRNA表达水平均高于空白对照组(P<0.05);As_(2)O_(3)+SAHA组的E-钙黏蛋白mRNA表达水平高于As_(2)O_(3)组、SAHA组(P<0.05)。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组的HDAC1蛋白表达水平均低于空白对照组(P<0.05);As_(2)O_(3)+SAHA组的HDAC1蛋白表达水平低于As_(2)O_(3)组、SAHA组(P<0.05)。As_(2)O_(3)组、SAHA组、As_(2)O_(3)+SAHA组E-钙黏蛋白的蛋白表达水平均高于空白对照组(P<0.05);As_(2)O_(3)+SAHA组E-钙黏蛋白的蛋白表达水平高于As_(2)O_(3)组、SAHA组(P<0.05)。结论:As_(2)O_(3)抑制Hela细胞的最佳浓度为8μmol/L,联合SAHA时,最佳抑制浓度为4μmol/L。As_(2)O_(3)可能通过抑制HDAC1的表达,同时促进升高E-钙黏蛋白的表达,与SAHA发挥协同作用抑制Hela细胞生长、侵袭、迁移。 展开更多
关键词 宫颈癌 HELA细胞 砒霜 三氧化二砷 伏立诺他 组蛋白脱乙酰基酶1 e-钙黏蛋白
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血清E-cadherin、VEGF、CYFRA21-1水平在甲状腺癌患者手术前后的变化及其对术后复发转移的预测价值
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作者 孙晓光 李彬 洪帅 《实用临床医学(江西)》 CAS 2024年第1期34-37,49,共5页
目的探讨血清E-钙粘连蛋白(E-cadherin)、血管内皮生长因子(VEGF)、细胞角蛋白19片段抗原21-1(CYFRA21-1)水平在甲状腺癌患者手术前后的变化及其对术后复发转移的预测价值。方法选取118例行甲状腺癌根治术的分化型甲状腺癌(DTC)患者为... 目的探讨血清E-钙粘连蛋白(E-cadherin)、血管内皮生长因子(VEGF)、细胞角蛋白19片段抗原21-1(CYFRA21-1)水平在甲状腺癌患者手术前后的变化及其对术后复发转移的预测价值。方法选取118例行甲状腺癌根治术的分化型甲状腺癌(DTC)患者为研究组,118例健康体检者为对照组;根据术后6个月复发转移情况,将DTC患者分为复发转移组33例与未复发转移组85例。比较对照组与研究组(术前)、研究组手术前后、复发转移组与未复发转移组血清E-cadherin、VEGF、CYFRA21-1水平,采用ROC曲线分析上述各指标对术后复发转移的预测价值。结果研究组血清E-cadherin水平显著低于对照组,血清VEGF、CYFRA21-1水平显著高于对照组(P<0.05);研究组术后2周血清E-cadherin水平显著高于术前,血清VEGF、CYFRA21-1水平显著低于术前(P<0.05);未复发转移组术后2周血清E-cadherin水平显著高于术后复发转移组,血清VEGF、CYFRA21-1水平显著低于术后复发转移组(P<0.05)。术后2周上述各指标联合检测预测DTC患者术后复发转移的AUC为0.862,敏感度为90.91%,特异度为75.29%。结论DTC患者术后血清中E-cadherin表达上调,VEGF、CYFRA21-1表达下调,各指标联合检测对复发转移具有较高的预测效能,可作为临床评估DTC患者术后复发转移情况的辅助指标。 展开更多
关键词 e-钙粘连蛋白 血管内皮生长因子 细胞角蛋白19片段抗原21-1 甲状腺癌 复发转移
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Evaluation of the water conservation function in the Ili River Delta of Central Asia based on the InVEST model 被引量:1
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作者 CAO Yijie MA Yonggang +2 位作者 BAO Anming CHANG Cun LIU Tie 《Journal of Arid Land》 SCIE CSCD 2023年第12期1455-1473,共19页
The Ili River Delta(IRD)is an ecological security barrier for the Lake Balkhash and an important water conservation area in Central Asia.In this study,we selected the IRD as a typical research area,and simulated the w... The Ili River Delta(IRD)is an ecological security barrier for the Lake Balkhash and an important water conservation area in Central Asia.In this study,we selected the IRD as a typical research area,and simulated the water yield and water conservation from 1975 to 2020 using the water yield module of the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)model.We further analyzed the temporal and spatial variations in the water yield and water conservation in the IRD from 1975 to 2020,and investigated the main driving factors(precipitation,potential evapotranspiration,land use/land cover change,and inflow from the Ili River)of the water conservation variation based on the linear regression,piecewise linear regression,and Pearson's correlation coefficient analyses.The results indicated that from 1975 to 2020,the water yield and water conservation in the IRD showed a decreasing trend,and the spatial distribution pattern was"high in the east and low in the west";overall,the water conservation of all land use types decreased slightly.The water conservation volume of grassland was the most reduced,although the area of grassland increased owing to the increased inflow from the Ili River.At the same time,the increased inflow has led to the expansion of wetland areas,the improvement of vegetation growth,and the increase of regional evapotranspiration,thus resulting in an overall reduction in the water conservation.The water conservation depth and precipitation had similar spatial distribution patterns;the change in climate factors was the main reason for the decline in the water conservation function in the delta.The reservoir in the upper reaches of the IRD regulated runoff into the Lake Balkhash,promoted vegetation restoration,and had a positive effect on the water conservation;however,this positive effect cannot offset the negative effect of enhanced evapotranspiration.These results provide a reference for the rational allocation of water resources and ecosystem protection in the IRD. 展开更多
关键词 water conservation function water yield Integrated valuation of Ecosystem Services and Tradeoffs(InVEST)model climate change land use/land cover change(LUCC) Ili River Delta Lake Balkhash
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监理质量E-旁站管理及应用研究
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作者 周亚平 余群舟 +2 位作者 骆汉宾 谢丹妮 杨传可 《工程管理学报》 2024年第2期142-147,共6页
旁站是监理开展工作的重要方式之一,随着信息技术在土建行业的广泛应用,传统的监理旁站无论是在旁站内容的确定、旁站信息的采集与记录方式,还是在旁站信息的推送与反馈等方面都有提升和改进空间。在阐述监理质量E-旁站的概念与管理框... 旁站是监理开展工作的重要方式之一,随着信息技术在土建行业的广泛应用,传统的监理旁站无论是在旁站内容的确定、旁站信息的采集与记录方式,还是在旁站信息的推送与反馈等方面都有提升和改进空间。在阐述监理质量E-旁站的概念与管理框架的基础上,引入POP模型辅助确定E-旁站内容,并对监理质量E-旁站需要采集的信息进行分类,提出了E-旁站信息采集的要求。基于管理关系和职责,构建了E-旁站信息推送与反馈程序;设计了监理E-旁站管理APP并应用于实际工程。通过构建E-旁站管理模式,保证了监理旁站工作的及时性、有效性和可追溯性,进而提高监理旁站的工作效果。 展开更多
关键词 监理质量控制 e-旁站 POP模型 旁站信息
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Mass Valuation of Unimproved Land Value Case Study: Nairobi County
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作者 Edwin Kochulem Dennis Mwaniki Felix Mutua 《Journal of Geographic Information System》 2023年第1期122-139,共18页
The purpose of this study is to investigate mass valuation of unimproved land value using machine learning techniques. The study was conducted in Nairobi County. It is one of the 47 Kenyan Counties under the 2010 cons... The purpose of this study is to investigate mass valuation of unimproved land value using machine learning techniques. The study was conducted in Nairobi County. It is one of the 47 Kenyan Counties under the 2010 constitution. A total of 1440 geocoded data points containing the market selling price of vacant land in Nairobi were web scraped from major property listing websites. These data points were adopted as dependent variables given as unit price of vacant land per square meter. The Covariates used in this study were categorized into Accessibility, Environmental, Physical and Socio-Economic Factors. Due to multi-collinearity problem present in the covariates, PLS and PCA methods were adopted to transform the observed features using a set of vectors. These methods resulted in an uncorrelated set of components that were used in training machine learning algorithms. The dependent variable and uncorrelated components derived feature reduction methods were used as training data for training different machine learning regression models namely;Random forest, support vector regression and extreme gradient boosting regression (XGboost regression). PLS performed better than PCA because the former maximizes the covariance between dependent and independent variables while the latter maximizes variance between the independent variables only and ignores the relationship between predictors and response. The first 9 components were identified as significant both by PLS and PCA methods. The spatial distribution of vacant land value within Nairobi County was consistent for all the three machine learning models. It was also noted that the land value pattern was higher in the central business district and the pattern spread northwards and westwards relative to the CBD. A relative low vacant land value pattern was observed on the eastern side of the county and also at the extreme periphery of Nairobi County boundary. From the accuracy metrics of R-squared and MAPE, Random Forest Regression model performed better than XGBoost and SVR models. This confirms the capability of random forest model to predict valid estimates of vacant land value for purposes of property taxation in Nairobi County. 展开更多
关键词 Machine Learning Property valuation GIS PLS PCA
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圈与路的点被多重集可区别的E-全染色 被引量:1
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作者 陈祥恩 曹静 《华东师范大学学报(自然科学版)》 CAS CSCD 北大核心 2024年第2期14-22,共9页
图G的E-全染色是指使得相邻顶点染以不同色,每条边与它的端点染以不同的颜色的全染色.设f是图G的E-全染色,图G的一个顶点x在f下的多重色集合C˜(x)是指点x的颜色以及与x关联的边的颜色构成的多重集.若图G的任意两个不同顶点在f下的多重... 图G的E-全染色是指使得相邻顶点染以不同色,每条边与它的端点染以不同的颜色的全染色.设f是图G的E-全染色,图G的一个顶点x在f下的多重色集合C˜(x)是指点x的颜色以及与x关联的边的颜色构成的多重集.若图G的任意两个不同顶点在f下的多重色集合不同,则f称为图G的点被多重集可区别的E-全染色.对图G进行点被多重集可区别的E-全染色所需用的最少的颜色的数目叫做G的点被多重集可区别的E-全色数.利用反证法和构造具体染色的方法,讨论了圈与路的点被多重集可区别的E-全染色问题,给出了圈与路的最优的点被多重集可区别的E-全染色方案,并确定了圈与路的点被多重集可区别的E-全色数. 展开更多
关键词 多重色集合 e-全染色 点被多重集可区别的e-全染色
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MMP25和E-cadherin在类风湿关节炎中的诊断价值
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作者 方全钢 刘海芸 +1 位作者 万静 张水生 《江西医药》 CAS 2024年第2期143-147,154,共6页
目的探讨基质金属蛋白酶25(Matrix metalloproteinase 25,MMP25)和E-钙黏蛋白(E-cadherin)对类风湿关节炎的诊断意义。方法选取2020年1月至2023年10月我院67例类风湿关节炎患者为实验组,同期50例健康体检人群为对照组;采用酶联免疫吸附... 目的探讨基质金属蛋白酶25(Matrix metalloproteinase 25,MMP25)和E-钙黏蛋白(E-cadherin)对类风湿关节炎的诊断意义。方法选取2020年1月至2023年10月我院67例类风湿关节炎患者为实验组,同期50例健康体检人群为对照组;采用酶联免疫吸附试验(ELISA)检测二组血清中MMP25和E-cadherin蛋白水平。收集实验组患者ESR、CRP、CCP、RF、DAS28-ESR、DAS28-CRP指标,以及是否为初诊、是否合并并发症(贫血、间质性肺炎等)、病程、临床活动度等级,并与MMP25和E-cadherin水平进行相关性分析。结果实验组血清MMP25和E-cadherin水平均高于对照组,差异均有统计学意义(P<0.001)。与ESR、CRP、CCP和RF等指标进行散点图和简单线性回归性分析,结果显示:不同临床活动度患者表达MMP25水平差异有统计学意义(P<0.001),MMP25与病程(β=0.479,P<0.001),MMP25与CRP(β=0.271,P<0.05),MMP25与DAS28-ESR(β=0.660,P<0.001)和MMP25与DAS28-CRP(β=0.624,P<0.001)均有相关性。不同临床活动度患者表达E-cadherin水平差异有统计学意义(P<0.001),E-cadherin与ESR(β=0.425,P<0.001),E-cadherin与CRP(β=0.328,P<0.05),E-cadherin与DAS28-ESR(β=0.746,P<0.001),E-cadherin与DAS28-CRP(β=0.671,P<0.001)均有相关性。多重线性回归分析结果显示,MMP25表达水平与临床活动度正相关(β=1.032,P<0.001),E-cadherin表达水平与临床活动度正相关(β=0.407,P<0.05)、与病程长短正相关(β=0.497,P<0.001)。结论MMP25和E-cadherin表达水平可以作为类风湿关节炎评估临床活动度的标志物,此外,E-cadherin表达水平也可以衡量患者病程长短。 展开更多
关键词 基质金属蛋白酶25 e-钙黏蛋白 类风湿关节炎 诊断价值
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Economic Valuation of Auctioned Tourist Hunting Blocks in Tanzania
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作者 Reuben M. J. Kadigi Imani R. Nkuwi +2 位作者 Fredrick A. Ligate Hamza Kija Emmanuel B. Musamba 《Open Journal of Ecology》 2023年第4期199-228,共30页
Economic valuation of ecosystems is increasingly being recognized as an important exercise to inform sustainable utilization and conservation of natural assets. It helps in planning and establishing fair profit margin... Economic valuation of ecosystems is increasingly being recognized as an important exercise to inform sustainable utilization and conservation of natural assets. It helps in planning and establishing fair profit margins that accrue either directly or indirectly from the consumptive and non-consumptive uses of ecosystem goods and services. This paper is based on a study which estimated the economic values of tourist hunting blocks (HBs) in Tanzania using the Analytic Multicriteria Valuation Method (AMUVAM). The study used a sample size of 12 out of 24 vacant hunting blocks which were to be auctioned to potential hunting companies in December 2022. The economic values of HBs were estimated using the time horizon of 10 years (the mean tenure for winning company). The results show that the economic values ranged from USD 6,215,588 to USD 653,470,695 per hunting block and the Existence Value (EV) constituted about 19% of the Total Economic Value (TEV). EV ranged from USD 632,210 to USD 125,147,285. The study underscores the need for decisions to allocate ecosystems, such as HBs, to both direct and indirect uses, to be guided by a though understanding of their values. We further recommend building the capacity of staff charged with the role of managing and allocating uses of these ecosystems to enable them undertake economic valuation of ecosystems using both simple and more robust analytical tools, such as the GIS, relational databases, and worldwide websites based tools, like InVEST (Integrated Valuation of Environmental Services and Tradeoffs), ARIES (Artificial Intelligence for Ecosystem Services), and Co$ting Nature. 展开更多
关键词 ECOSYSTEMS Total Economic Value Biodiversity Conservation Analytic Multicriteria valuation Method Hunting Blocks
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Estimating the value of a statistical life in China: A contingent valuation study in six representative cities
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作者 Chaoji Cao Xinke Song +5 位作者 Wenjia Cai Yichao Li Jianhui Cong Xueying Yu Mengzhao Gao Can Wang 《Chinese Journal of Population,Resources and Environment》 2023年第4期269-278,共10页
The value of a statistical life(VSL)is a crucial tool for monetizing health impacts.To explore the VSL in China,this study examines people’s willingness to pay(WTP)to reduce death risk from air pollution in six repre... The value of a statistical life(VSL)is a crucial tool for monetizing health impacts.To explore the VSL in China,this study examines people’s willingness to pay(WTP)to reduce death risk from air pollution in six representative cities in China based on face-to-face contingent valuation interviews(n=3936)from March 7,2019 to September 30,2019.The results reveal that the WTP varied from CNY 455 to 763 in 2019(USD 66-111),corresponding to a VSL range of CNY 3.79-6.36 million(USD 549395-921940).The VSL in China in 2019 is estimated to be CNY 4.76 million(USD 689659).The statistics indicate that monthly expenditure levels,environmental concerns,risk attitudes,and assumed market acceptance,which have seldom been dis‐cussed in previous studies,significantly impact WTP and VSL.These findings will serve as a reference for ana‐lyzing mortality risk reduction benefits in future research and for policymaking. 展开更多
关键词 Air pollution Contingent valuation method Willingness to pay Value of a statistical life China
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基于e-阈值生成模糊蕴涵的新方法
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作者 张程 覃锋 《云南大学学报(自然科学版)》 CAS CSCD 北大核心 2024年第3期411-421,共11页
借助e-阈值和2个给定的模糊蕴涵,提出了一种构造模糊蕴涵的新方法;然后研究了新构造的模糊蕴涵的性质,接着揭示了与其它e-阈值生成模糊蕴涵的关系;最后,将这种构造方法推广到一族模糊蕴涵上,研究了它的一些性质并对它进行了刻画.
关键词 模糊连接词 模糊蕴涵 e-阈值生成蕴涵
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Evaluation and Quantitative Attribution Analysis of Water Yield Services in the Peak-cluster Depression Basins in Southwest of Guangxi,China
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作者 WANG Donghua TIAN Yichao +5 位作者 ZHANG Yali HUANG Liangliang TAO Jin YANG Yongwei LIN Junliang ZHANG Qiang 《Chinese Geographical Science》 SCIE CSCD 2023年第1期116-130,共15页
Karst environmental issues have become one of the hot spots in contemporary international geological research. The same problem of water shortage is one of the hot spots of global concern. The peak-cluster depression ... Karst environmental issues have become one of the hot spots in contemporary international geological research. The same problem of water shortage is one of the hot spots of global concern. The peak-cluster depression basins in southwest of Guangxi is an important water connotation and ecological barrier areas in the Pearl River Basin of China. Thus, studying the spatial and temporal variations and the influencing factors of its water yield services is critical to achieve the sustainable development of water resources and ecological environmental protection in this region. As such, this paper uses the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST) model to assess the spatial and temporal variabilities of water yield services and its trends in the peak-cluster depression basins in southwest of Guangxi from 2000 to 2020. This work also integrates precipitation(Pre), reference evapotranspiration(ET), temperature(Tem), digital elevation model(DEM), slope, normalized difference vegetation index(NDVI), land use/land cover(LULC) and soil type to reveal the main factors that influence water yield services with the help of Geodetector. Results show that: 1) in time scale,the total annual water yield in the study area show a fluctuating and increasing trend from 2000 to 2020, with a growth rate of 7.3753 × 10^(8)m^(3)/yr, and its multi-year average water yield was 538.07 mm;2) in spatial pattern, with high yield areas mainly distributed in the south of the study area(mainly including Shangsi County, Pingxiang City, Ningming County, Longzhou County and Jingxi County), and low yield areas mainly distributed in Baise City and Nanning City;3) the dominant factor of water yield within karst and non-karst landforms is not necessarily controlled by precipitation, and the explanation degree of DEM factors in karst areas is significantly higher than that in non-karst areas;4) amongst the climatic factors, Pre, ET and Tem are dominant in the spatial pattern of region water yield capacity. among which Pre has the highest explanatory power for the spatial heterogeneity of annual water production, with q values above0.8, and each driver showed a significant interaction on the spatial distribution of water yield, with Pre exhibiting the strongest interaction with LULC. 展开更多
关键词 water yield Integrated valuation of Ecosystem Services and Trade-offs(InVEST) Geodetector peak-cluster depression basins in southwest of Guangxi China
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血清β-catenin、E-cadherin水平与糖尿病肾病患者钙磷代谢、颈动脉钙化的关系
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作者 高剑 梁铮 +2 位作者 赵飞 刘小静 马宁 《国际检验医学杂志》 CAS 2024年第12期1469-1473,共5页
目的探讨血清E-钙黏蛋白(E-cadherin)、β-连环蛋白(β-catenin)水平与糖尿病肾病患者钙磷代谢、颈动脉钙化的关系。方法选择2019年5月至2022年11月该院收治的112例糖尿病肾病患者作为研究组,并根据双侧颈动脉彩超检查结果分为颈动脉钙... 目的探讨血清E-钙黏蛋白(E-cadherin)、β-连环蛋白(β-catenin)水平与糖尿病肾病患者钙磷代谢、颈动脉钙化的关系。方法选择2019年5月至2022年11月该院收治的112例糖尿病肾病患者作为研究组,并根据双侧颈动脉彩超检查结果分为颈动脉钙化组(n=44)和非颈动脉钙化组(n=68),另选同期于该院接受体检的90例体检健康者为对照组。检测并比较各组血清E-cadherin、β-catenin及钙磷代谢水平,采用Pearson相关分析血清E-cadherin、β-catenin水平与糖尿病肾病患者钙磷代谢的关系,采用受试者工作特征(ROC)曲线评估血清E-cadherin、β-catenin对糖尿病肾病患者颈动脉钙化的预测价值,采用多因素Logistic回归分析糖尿病肾病患者颈动脉钙化的影响因素。结果研究组糖化血红蛋白、血磷、钙磷乘积、甲状旁腺激素(iPTH)、肌酐、碱性磷酸酶、β-catenin水平均高于对照组,E-cadherin水平低于对照组(P<0.05)。颈动脉钙化组血磷、血钙、钙磷乘积、iPTH、肌酐、碱性磷酸酶、β-catenin水平均高于非颈动脉钙化组,E-cadherin水平低于非颈动脉钙化组(P<0.001)。Pearson相关分析显示,糖尿病肾病患者血清E-cadherin与血磷、血钙、钙磷乘积、iPTH、肌酐、碱性磷酸酶均呈负相关(r=-0.453、-0.654、-0.365、-0.490、-0.411、-0.377,均P<0.05),血清β-catenin水平与血磷、血钙、钙磷乘积、iPTH、肌酐、碱性磷酸酶均呈正相关(r=0.444、0.345、0.421、0.398、0.651、0.622,均P<0.001)。ROC曲线分析显示,血清E-cadherin、β-catenin及二者联合预测糖尿病肾病颈动脉钙化的曲线下面积分别为0.844(95%CI 0.795~0.894)、0.853(95%CI 0.801~0.901)、0.901(95%CI 0.851~0.952)。多因素Logistic回归分析显示,血清E-cadherin(OR=3.789,95%CI 2.055~6.983)、β-catenin(OR=4.104,95%CI 1.795~9.385)、钙磷乘积(OR=2.998,95%CI 1.895~4.743)、iPTH(OR=2.713,95%CI 1.787~4.118)均是糖尿病肾病患者颈动脉钙化的影响因素(P<0.05)。结论糖尿病肾病患者β-catenin水平升高,E-cadherin水平降低,二者与患者钙磷代谢、颈动脉钙化密切相关,可作为评估糖尿病肾病患者颈动脉钙化的有效指标,同时二者联合对颈动脉钙化的预测价值更高。 展开更多
关键词 糖尿病肾病 e-钙黏蛋白 Β-连环蛋白 钙磷代谢 颈动脉钙化
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miR-30e-5p靶向BIM调控缺氧诱导细胞凋亡的应用研究
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作者 吴宁夏 李飞 《临床医学进展》 2024年第6期344-352,共9页
目的:研究miR-30e-5p与H2O2损伤后心肌细胞凋亡的关系,探讨miR-30e-5p靶向BIM基因调控H2O2损伤后心肌细胞凋亡的作用,为心肌梗死的诊断以及治疗提供新的靶点。方法:将40天CA16分为正常组(N)、缺氧组(H)、过表达对照组(NC+H)、miR-30e-5... 目的:研究miR-30e-5p与H2O2损伤后心肌细胞凋亡的关系,探讨miR-30e-5p靶向BIM基因调控H2O2损伤后心肌细胞凋亡的作用,为心肌梗死的诊断以及治疗提供新的靶点。方法:将40天CA16分为正常组(N)、缺氧组(H)、过表达对照组(NC+H)、miR-30e-5p过表达组(miR+H)。N组置于正常培养箱下培养;H组置于缺氧培养箱培养24 h;NC+H组与miR+H组分别为稳定感染装载有miR-NC和miR-30e-5p的重组慢病毒后缺氧处理24 h。应用RT-qPCR检测CA16中miR-30e-5p和BIM的mRNA表达水平,应用Caspase-3活性实验和流式细胞技术检测hiPSC-CMs的凋亡水平。利用生物信息学miRNA数据库预测miR-30e-5p的靶基因,并应用双荧光素酶报告基因实验进行验证。结果:1) 与N组比较,H组miR-30e-5p表达水平明显下调;与NC+H组比较,miR+H组miR-30e-5p表达水平则明显上调。2) 与N组比较,H组Caspase-3活性水平明显升高;与NC+H组比较,miR+H组Caspase-3活性水平下降。3) 与N组比较,H组CA16细胞凋亡比例明显上升;与NC+H组比较,miR+H组CA16凋亡比例则明显下降。4) 与N组比较,H组蛋白BIM表达水平上调;与NC+H组比较,miR+H组蛋白BIM表达水平下调。5) 通过miRNA数据库分析发现BIM是miR-30e-5p的潜在靶基因之一。结论:1) miR-30e-5p调控缺氧诱导CA16的凋亡。2) BIM是miR-30e-5p的靶基因之一。3) miR-30e-5p靶向BIM调控缺氧诱导CA16的凋亡。4) miR-30e-5p在急性心肌梗死的发生、发展过程中可能发挥抑癌基因的作用。 展开更多
关键词 miR-30e-5p CA16 抑制缺氧 凋亡
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完全二部图K_(4,n)的点被多重集可区别的E-全染色
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作者 郭亚勤 陈祥恩 《吉林大学学报(理学版)》 CAS 北大核心 2024年第3期480-486,共7页
利用反证法、色集合事先分配法及构造具体染色等方法,讨论完全二部图K_(4,n)的点被多重集可区别的E-全染色,并确定K_(4,n)的点被多重集可区别的E-全色数.
关键词 完全二部图 e-全染色 e-全色数 多重集 色集合
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基于多种方法的小型蒸发与E-601型蒸发器蒸发量折算分析及应用
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作者 王君军 吴和俐 +1 位作者 敖芹 李扬 《山地气象学报》 2024年第2期62-67,共6页
【目的】探明贵阳蒸发量特征,为该市山塘水库蓄水等方面提供参考。【方法】利用贵阳市1983—2001年小型与E-601型蒸发器同期观测资料,运用折算系数法、线性回归法和多元回归法对小型蒸发量进行折算并与E-601型蒸发量对比检验,选择最优... 【目的】探明贵阳蒸发量特征,为该市山塘水库蓄水等方面提供参考。【方法】利用贵阳市1983—2001年小型与E-601型蒸发器同期观测资料,运用折算系数法、线性回归法和多元回归法对小型蒸发量进行折算并与E-601型蒸发量对比检验,选择最优方法折算小型蒸发资料延长大型蒸发序列,进而对蒸发量特征进行研究。【结果】小型与E-601型蒸发量之间存在显著相关。气温越高、日照越长、湿度越低、云量越少,蒸发量就越大,反之越低。小型较E-601型蒸发量年平均偏大61.3%,各月偏大43.5%~78.1%。E-601型蒸发器测量的蒸发值更能代表当地气候特征。折算系数、线性回归、多元回归模型均能对小型蒸发量进行较好地折算,为延长大型蒸发序列提供科学依据,其中线性回归法和折算系数法简单快捷,而多元回归模型则更适用于日值折算,计算较复杂。【结论】近62 a来贵阳市蒸发量呈增多趋势,其中上半年趋于减少,下半年趋于增多;结合降水量计算水分盈亏量发现贵阳市夏半年水分盈余集中期出现在5—7月,冬半年水分亏损期长,留冬用水充足。 展开更多
关键词 e-601型蒸发 小型蒸发 折算 贵阳
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完全二部图K5,n(n ≥ 7114)的点被多重集可区别的E-全染色
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作者 郭亚勤 《理论数学》 2024年第7期163-172,共10页
利用反证法、色集合事先分配法以及构造具体染色等方法,探讨了完全二部图K5,n(n ≥ 7114)的点被多重集可区别的E-全染色,确定了这一类图的点被多重集可区别的E-全色数。
关键词 完全二部图 e-全染色 e-全色数 多重集
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Spatiotemporal variations in ecosystem services and their trade-offs and synergies against the background of the gully control and land consolidation project on the Loess Plateau,China
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作者 WANG Jing WEI Yulu +2 位作者 PENG Biao LIU Siqi LI Jianfeng 《Journal of Arid Land》 SCIE CSCD 2024年第1期131-145,共15页
Studying the spatiotemporal variations in ecosystem services and their interrelationships on the Loess Plateau against the background of the gully control and land consolidation(GCLC)project has significant implicatio... Studying the spatiotemporal variations in ecosystem services and their interrelationships on the Loess Plateau against the background of the gully control and land consolidation(GCLC)project has significant implications for ecological protection and quality development of the Yellow River Basin.Therefore,in this study,we took Yan'an City,Shaanxi Province of China,as the study area,selected four typical ecosystem services,including soil conservation service,water yield service,carbon storage service,and habitat quality service,and quantitatively evaluated the spatiotemporal variation characteristics and trade-offs and synergies of ecosystem services from 2010 to 2018 using the Integrated Valuation of Ecosystem Services and Trade-offs(InVEST)model.We also analysed the relationship between the GCLC project and regional ecosystem service changes in various regions(including 1 city,2 districts,and 10 counties)of Yan'an City and proposed a coordinated development strategy between the GCLC project and the ecological environment.The results showed that,from 2010 to 2018,soil conservation service decreased by 7.76%,while the other three ecosystem services changed relatively little,with water yield service increasing by 0.56% and carbon storage service and habitat quality service decreasing by 0.16% and 0.14%,respectively.The ecological environment of Yan'an City developed in a balanced way between 2010 and 2018,and the four ecosystem services showed synergistic relationships,among which the synergistic relationships between soil conservation service and water yield service and between carbon storage service and habitat quality service were significant.The GCLC project had a negative impact on the ecosystem services of Yan'an City,and the impact on carbon storage service was more significant.This study provides a theoretical basis for the scientific evaluation of the ecological benefits of the GCLC project and the realization of a win-win situation between food security and ecological security. 展开更多
关键词 ecosystem services trade-offs and synergies gully control and land consolidation habitat quality Integrated valuation of Ecosystem Services and Trade-offs(InVEST)model Loess Plateau
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