The Chaling wild abortive type （CL-type） cytoplasmic male sterile line, E-Jing A, was characterized by stable sterility with a sterile plant percentage of 100%, a pollen sterile degree of 98% with dominated typical ...The Chaling wild abortive type （CL-type） cytoplasmic male sterile line, E-Jing A, was characterized by stable sterility with a sterile plant percentage of 100%, a pollen sterile degree of 98% with dominated typical abortive pollens, and showed the characteristics of good outcrossing with a stigma exsertion rate of 48.2% and an outcrossing rate varied from 30% to 50%, good combining ability, and fine grain quality. E-Jing A was sensitive to temperature. Its duration from sowing to heading was 78-90 d when it was sown from mid May to early June at Wuhan. The breeding procedure of E-Jing A and its characteristics, relationship of restoring and maintaining were introduced.展开更多
目的观察盲肠结扎穿孔术(CLP)脓毒症模型大鼠心肌损伤的发生情况,以及应用中药912液进行干预的效果及其对心肌的保护作用机制。方法采用CLP制备脓毒症大鼠模型;按照随机数字表法分组。共有56只存活Wistar大鼠进入该实验,其中假手术组8只...目的观察盲肠结扎穿孔术(CLP)脓毒症模型大鼠心肌损伤的发生情况,以及应用中药912液进行干预的效果及其对心肌的保护作用机制。方法采用CLP制备脓毒症大鼠模型;按照随机数字表法分组。共有56只存活Wistar大鼠进入该实验,其中假手术组8只,CLP模型组24只,中药912液治疗组24只,后两组再分为术后3、24和72 h 3个时间点亚组。观察各组不同时间点心肌损伤指标〔肌钙蛋白T(TnT)、脑钠素(BNP)〕,血清炎症因子水平〔肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、IL-10〕和血浆一氧化氮(NO)、丙二醛(MDA)的动态变化。结果CLP模型组大鼠术后3 h血浆TnT、TNF-α、IL-6、NO、MDA水平即开始较假手术组明显升高,BNP、IL-10到24 h时也明显升高(P<0.05或P<0.01);而中药912液组的TnT、BNP、TNF-α、IL-6、NO、MDA虽较假手术组升高,但明显低于CLP模型组,IL-10则高于CLP模型组(P<0.05或P<0.01)。结论脓毒症后可出现明显的心肌损伤,中药912液可通过抑制NO和自由基介导的组织损伤改善脓毒症时的心肌损伤。展开更多
基金Supported by the Great Special Science and Technology Project of Hubei Province during the Eleventh Five-Year Plan(2006AA201A03)~~
文摘The Chaling wild abortive type （CL-type） cytoplasmic male sterile line, E-Jing A, was characterized by stable sterility with a sterile plant percentage of 100%, a pollen sterile degree of 98% with dominated typical abortive pollens, and showed the characteristics of good outcrossing with a stigma exsertion rate of 48.2% and an outcrossing rate varied from 30% to 50%, good combining ability, and fine grain quality. E-Jing A was sensitive to temperature. Its duration from sowing to heading was 78-90 d when it was sown from mid May to early June at Wuhan. The breeding procedure of E-Jing A and its characteristics, relationship of restoring and maintaining were introduced.
文摘目的观察盲肠结扎穿孔术(CLP)脓毒症模型大鼠心肌损伤的发生情况,以及应用中药912液进行干预的效果及其对心肌的保护作用机制。方法采用CLP制备脓毒症大鼠模型;按照随机数字表法分组。共有56只存活Wistar大鼠进入该实验,其中假手术组8只,CLP模型组24只,中药912液治疗组24只,后两组再分为术后3、24和72 h 3个时间点亚组。观察各组不同时间点心肌损伤指标〔肌钙蛋白T(TnT)、脑钠素(BNP)〕,血清炎症因子水平〔肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、IL-10〕和血浆一氧化氮(NO)、丙二醛(MDA)的动态变化。结果CLP模型组大鼠术后3 h血浆TnT、TNF-α、IL-6、NO、MDA水平即开始较假手术组明显升高,BNP、IL-10到24 h时也明显升高(P<0.05或P<0.01);而中药912液组的TnT、BNP、TNF-α、IL-6、NO、MDA虽较假手术组升高,但明显低于CLP模型组,IL-10则高于CLP模型组(P<0.05或P<0.01)。结论脓毒症后可出现明显的心肌损伤,中药912液可通过抑制NO和自由基介导的组织损伤改善脓毒症时的心肌损伤。
