A diode-end-pumped Q-switched high-efficiency Nd, Cr：YAG laser with simultaneous dual-wavelength emission at 946nm and 1.3μm is demonstrated. The maximum output power of 1.93 W with simultaneous dual-wavelength oper...A diode-end-pumped Q-switched high-efficiency Nd, Cr：YAG laser with simultaneous dual-wavelength emission at 946nm and 1.3μm is demonstrated. The maximum output power of 1.93 W with simultaneous dual-wavelength operation is achieved at an absorbed pump power of 13.32 W and an absorbed slope efficiency of 15.15%. The maximum optical-optical efficiency is 14.49% with pulse widths of 16.38ns at 946nm and 26.65ns at 1.3μm. A maximum total repetition rate of 43.25 kHz is obtained.展开更多
目的探讨祛湿清热针刺疗法对急性湿疹患者AhR、IFN-γ、EOS、IL-17水平的影响。方法选取2021年11月—2023年7月期间于马鞍山中医院收治的78例急性湿疹患者,采用随机数字表法分为对照组和治疗组,每组各39例。对照组给予常规治疗,治疗组...目的探讨祛湿清热针刺疗法对急性湿疹患者AhR、IFN-γ、EOS、IL-17水平的影响。方法选取2021年11月—2023年7月期间于马鞍山中医院收治的78例急性湿疹患者,采用随机数字表法分为对照组和治疗组,每组各39例。对照组给予常规治疗,治疗组给予祛湿清热针刺疗法治疗。治疗2周后,观察比较两组患者临床疗效、不良反应情况,治疗前后中医证候评分、湿疹面积及严重度指数(Eczema area and severity index,EASI)评分、视觉模拟评分法(Visual pain scale,VAS)评分、实验室检查指标[嗜酸性粒细胞(Eosinophil,EOS)、白细胞介素-17(Interleukin-17,IL-17)、干扰素-γ(Interferon,IFN-γ)、芳香烃受体(Aromatic hydrocarbon receptor,AhR)]、皮肤生理功能指标。结果治疗后治疗组临床总有效率97.44%(38/39)明显高于对照组82.05%(32/39),差异有统计学意义(P<0.05)。治疗后两组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者EASI、VAS评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组EASI、VAS评分均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者AhR、IL-17、IFN-γ、EOS水平均较治疗前降低,差异有统计学意义(P<0.05);且治疗组AhR、IL-17、IFN-γ、EOS水平均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者皮肤生理功能指标较治疗前升高,差异有统计学意义(P<0.05);且治疗组皮肤生理功能指标较对照组明显升高,差异有统计学意义(P<0.05)。治疗期间,治疗组不良反应发生率7.69%(3/39)与对照组17.95%(7/39)比较,差异无统计学意义(P>0.05)。结论祛湿清热针刺疗法能够有效降低急性湿疹患者AhR、IFN-γ、EOS、IL-17水平,降低炎症反应,疗效明显。展开更多
A high-performance LED-side-pumped two-rod Nd,Ce:YAG laser with continuous-wave(CW) and acousto–optical(A-O) Q-switched operation is demonstrated in this work. A symmetrically shaped flat–flat cavity with two identi...A high-performance LED-side-pumped two-rod Nd,Ce:YAG laser with continuous-wave(CW) and acousto–optical(A-O) Q-switched operation is demonstrated in this work. A symmetrically shaped flat–flat cavity with two identical LEDside-pumped laser modules is employed for power scalability. In the CW regime, the maximum output average power of laser at 1064 nm is 4.41 W, corresponding to a maximum optical conversion efficiency of 5.3% and a slope efficiency is 12.4%. In the active Q-switched regime, the pulse energy of laser reaches as high as 0.89 m J at a repetition rate of 800 Hz with a pulse width of 457.2 ns, the corresponding highest peak output power is 1.94 k W and the M~2 factor is measured to be about 8.8. To the best of the authors' knowledge, this is the first demonstration and the highest performance of a CW LED-side-pumped two-rod laser Nd,Ce:YAG with Watt-level output reported so far.展开更多
随着政企和金融客户对光传送网(optical transport network, OTN)专线业务开通时效、保护等级、网络复用要求的不断提升,政企大管道OTN专线已无法满足省内客户小颗粒带宽需求。同时,运营商OTN网络存在多厂家控制系统无法统一的问题,政...随着政企和金融客户对光传送网(optical transport network, OTN)专线业务开通时效、保护等级、网络复用要求的不断提升,政企大管道OTN专线已无法满足省内客户小颗粒带宽需求。同时,运营商OTN网络存在多厂家控制系统无法统一的问题,政企用户对跨域小颗粒专线开通和管理需求日益突出,迫切需要新型的跨域小颗粒承载技术,实现OTN专线端到端的自动发放。本文基于OTN网络多厂家管控系统的VC时隙互通原理和商用分布式应用设计的一款区块链操作系统(enterprise operation system, EOS),提出了一种新型跨域EOS业务开通技术,实现了异厂家协同、端到端、小颗粒的政企OTN业务专线应用。展开更多
基金Supported by the National Basic Research Program of China under Grant No 2013CB632704
文摘A diode-end-pumped Q-switched high-efficiency Nd, Cr：YAG laser with simultaneous dual-wavelength emission at 946nm and 1.3μm is demonstrated. The maximum output power of 1.93 W with simultaneous dual-wavelength operation is achieved at an absorbed pump power of 13.32 W and an absorbed slope efficiency of 15.15%. The maximum optical-optical efficiency is 14.49% with pulse widths of 16.38ns at 946nm and 26.65ns at 1.3μm. A maximum total repetition rate of 43.25 kHz is obtained.
文摘目的探讨祛湿清热针刺疗法对急性湿疹患者AhR、IFN-γ、EOS、IL-17水平的影响。方法选取2021年11月—2023年7月期间于马鞍山中医院收治的78例急性湿疹患者,采用随机数字表法分为对照组和治疗组,每组各39例。对照组给予常规治疗,治疗组给予祛湿清热针刺疗法治疗。治疗2周后,观察比较两组患者临床疗效、不良反应情况,治疗前后中医证候评分、湿疹面积及严重度指数(Eczema area and severity index,EASI)评分、视觉模拟评分法(Visual pain scale,VAS)评分、实验室检查指标[嗜酸性粒细胞(Eosinophil,EOS)、白细胞介素-17(Interleukin-17,IL-17)、干扰素-γ(Interferon,IFN-γ)、芳香烃受体(Aromatic hydrocarbon receptor,AhR)]、皮肤生理功能指标。结果治疗后治疗组临床总有效率97.44%(38/39)明显高于对照组82.05%(32/39),差异有统计学意义(P<0.05)。治疗后两组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者EASI、VAS评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组EASI、VAS评分均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者AhR、IL-17、IFN-γ、EOS水平均较治疗前降低,差异有统计学意义(P<0.05);且治疗组AhR、IL-17、IFN-γ、EOS水平均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者皮肤生理功能指标较治疗前升高,差异有统计学意义(P<0.05);且治疗组皮肤生理功能指标较对照组明显升高,差异有统计学意义(P<0.05)。治疗期间,治疗组不良反应发生率7.69%(3/39)与对照组17.95%(7/39)比较,差异无统计学意义(P>0.05)。结论祛湿清热针刺疗法能够有效降低急性湿疹患者AhR、IFN-γ、EOS、IL-17水平,降低炎症反应,疗效明显。
基金Project supported by the Fund from Nanjing University of Posts and Telecommunications,China(Grant Nos.JUH219002 and JUH219007)the Key Research and Development Program of Shandong Province,China(Grant No.2021CXGC010202)。
文摘A high-performance LED-side-pumped two-rod Nd,Ce:YAG laser with continuous-wave(CW) and acousto–optical(A-O) Q-switched operation is demonstrated in this work. A symmetrically shaped flat–flat cavity with two identical LEDside-pumped laser modules is employed for power scalability. In the CW regime, the maximum output average power of laser at 1064 nm is 4.41 W, corresponding to a maximum optical conversion efficiency of 5.3% and a slope efficiency is 12.4%. In the active Q-switched regime, the pulse energy of laser reaches as high as 0.89 m J at a repetition rate of 800 Hz with a pulse width of 457.2 ns, the corresponding highest peak output power is 1.94 k W and the M~2 factor is measured to be about 8.8. To the best of the authors' knowledge, this is the first demonstration and the highest performance of a CW LED-side-pumped two-rod laser Nd,Ce:YAG with Watt-level output reported so far.
