Improvement of Binocular Reconstruction Algorithm for Measuring 3D Pavement Texture Using a Single Laser Line Scanning Constraint

The dense and accurate measurement of 3D texture is helpful in evaluating the pavement function.To form dense mandatory constraints and improve matching accuracy,the traditional binocular reconstruction technology was improved threefold.First,a single moving laser line was introduced to carry out global scanning constraints on the target,which would well overcome the difficulty of installing and recognizing excessive laser lines.Second,four kinds of improved algorithms,namely,disparity replacement,superposition synthesis,subregion segmentation,and subregion segmentation centroid enhancement,were established based on different constraint mechanism.Last,the improved binocular reconstruction test device was developed to realize the dual functions of 3D texture measurement and precision self-evaluation.Results show that compared with traditional algorithms,the introduction of a single laser line scanning constraint is helpful in improving the measurement’s accuracy.Among various improved algorithms,the improvement effect of the subregion segmentation centroid enhancement method is the best.It has a good effect on both overall measurement and single pointmeasurement,which can be considered to be used in pavement function evaluation.

Contragestazol (DL111-IT) inhibits proliferation of human androgen-independent prostate cancer cell line PC3 in vitro and in vivo

Aim： To evaluate the antiproliferative activity of contragestazol （DL111-IT） on the human prostate cancer cell line PC3 in vitro and in vivo and to elucidate its potential molecular mechanisms. Methods： The cell killing ability of DL111-IT was measured by the 3-（4,5-dimethylthia-zol,2-yl）-2,5-diphenyltetrazolium bromide （MTT） reagent assay method and the tumor xenograft model. The cell cycle was analyzed by flow cytometry and protein expression, including retinoblastoma （pRb）, cyclin-dependent kinase 4 （CDK4） and cyclin D 1, was detected by Western blotting. Results： DL111-IT exhibited high efficiency on cell growth inhibition of the human androgen-independent prostate cancer cell line PC3. The drug concentration that yielded 50 % cell inhibition （IC50 value） was 9.9 mg/mL. In the PC3 tumor xenograft study, DL111-IT （1.25 mg/kg-20.0 mg/kg） given once a day for 10 days significantly inhibited tumor growth, with the inhibition rate ranging from 21% to 50 %. Flow cytometric analysis indicated that DL111-IT could cause GI arrest in the PC3 cell line, but not apoptosis. DL111-IT enhanced pRb expression and down-regulated CDK4 and cyclin D 1 expression, suggesting that cell cycle regulation might contribute to the anticancer property of DL 111- IT. Conclusion： DL111-1T inhibits the proliferation of human androgen-independent prostate cancer cell line PC3 in vitro and in vivo by a cell cycle regulation pathway.

STUDY ON THREE-DIMENSIONAL FINITE BODIES CONTAINING CRACKS USING THE FINITE ELEMENT METHOD OF LINES

The three-dimensional finite element method of lines is presented, and the basic processing description of 3D FEMOL in cracking questions is given in detail. Applications to 3D bodies with cracks indicate that good accuracy can be obtained with relatively coarse girds. In particular, application to the tension specimen shows very good agreement with the evaluation of stress intensity factors, which is better than the results of other methods. This implies a considerable potential for using this method in the 3D analysis of finite geometry solids and suggests a possible extension of this technique to nonlinear material behavior.

Application of 2-D and 3-D Geo-electrical Resistivity Tomography and Geotechnical Soil Evaluation for Engineering Site Investigation:A Case Study of Okerenkoko Primary School,Warri-Southwest,Delta State,Nigeria

In the design of building structures,joint efforts must be decided to resolve the depth of competent layers across the intended site to safeguard the durability of civil engineering structures and to avert the disastrous consequences of structural failure and collapse.In this study,an integrated methodology that employed DC resistivity tomography involving 2-D and 3-D techniques and geotechnical-soil analysis was used to evaluate subsoil conditions for engineering site investigation at Okerenkoko primary school,in the Warri-southwest area of Delta State,to adduce the phenomena responsible for the visible cracks/structural failure observed in the buildings.The results obtained brought to light the geological structure beneath the subsurface,which consists of four geoelectric layers identified as topsoil,dry/lithified upper sandy layer,wet sand(water-saturated)and peat/clay/sandy clayey soil(highly water-saturated).The deeply-seated peat/clay materials(ρ≤20Ωm)were delineated in the study area to the depths of 17.1 m and 19.8 m from 2-D and 3-D tomography respectively.3-D images presented as horizontal depth slices revealed the dominance of very low resistivity materials i.e.peat/clay/sandy clay within the fourth,fifth and sixth layers at depths ranging from 8.68-12.5 m,12.5-16.9 m and 16.9-21.9 m respectively.The dominance of mechanically unstable peat/clay/sandy clay layers beneath the subsurface,which are highly mobile in response to volumetric changes,is responsible for the noticeable cracks/failure detected on structures within the study site.These observations were validated by a geotechnical test of soil samples in the study area.Atterberg’s limits of the samples revealed plasticity indices of zero.Thus,the soil samples within the depth analyzed were representatives of sandy soil that does not possess any plasticity.The methods justifiably provided relevant information on the subsurface geology beneath the study site and should be appropriated as major tools for engineering site assessment/geotechnical projects.

3D object reconstruction by point coordinates of 2D line drawings

It is a research subject in computer vision to 3D reconstruction of an object represented by a single 2D line drawing. Previous works on 3D reconstruction from 2D line drawings focus on objects with lines, plane, view, and so on. This paper mainly studies the 3D reconstruction from 2D line drawings. Besides, a new approach is proposed： it is that for the research of the point coordinates of 2D line drawings, so as to achieve the object reconstruction by the reconstruction of point coordinates. The reconstruction process includes： （1） the collection of point coordinates （X,Y） of 2D line drawings; （2） the derivation of mathematical formula about the reconstruction of the point of 2D line drawings, and calculating the corresponding point of the 3D coordinates; （3） the regeneration of 3D graphics with 3D points; （4） analyze error by the proportional of parallel of axonometric projection, in order to prove the accuracy of the method.

3D Geology Modeling from 2D Prospecting Line Profile Map

Using prospecting line profile map in combination with drilling and other information for 3D reconstruction of geological model is an important method of 3D geological modeling.?This paper?discusses the theory and implementation method of 2D prospecting line map into 3D prospecting line map and then into 3D model. The authors propose that it needs twice upgrading dimension to reconstruction 3D geology model from prospecting line profile map. The first upgrading dimension is to convert profile from 2D into 3D profile,?i.e.?the 2D points in the 2D profile map upgrading dimensional transformation to 3D points in a 3D profile. The second upgrading dimension is that transform 0D point 1D curve and 2D polygon feature into 1D curve, 2D surface and 3D solid feature. The paper reexamines contents and forms in prospecting line map from the two different viewpoints of geology and geographic information science. The process of 3D geology modeling from 2D prospecting map is summarized as follows. Firstly, profile is divided into several sections by beginning, end and drill point of the prospecting line. Next, a 3D folded upright profile frame is built by 2D folded prospecting line on the plan map. Then, 2D points of features on 2D profile are converted into 3D points on 3D profile section by section. And then, adding switch control points for the long line crossover two segments. Lastly, 1D curve features are upgraded to 2D surface.

3D Reconstruction from 2D Line Drawings only with Visible Vertices and Edges

The human vision system can reconstruct a 3D object easily from single 2D line drawings even if the hidden lines of the object are invisible. Now, there are many methods have emulated this ability, but when the hidden lines of the object are invisible, these methods cannot reconstruct a complete 3D object. Therefore, we put forward a new algorithm to settle this hard problem. Our approach consists of two steps： （1） infer the invisible vertices and edges to complete the line drawing, （2） propose a vertex-based optimization method to reconstruct a 3D object.

3D reconstruction of complex curved objects from line drawings

An active research topic in computer vision and graphics is developing algorithms that can reconstruct the 3D surface of curved objects from line drawings. There are a number of algorithms have been dedicated to solve this problem, but they can＇t solve this problem when the geometric structure of a curved object becomes complex. This paper proposes a novel approach to reconstructing a complex curved 3D object from single 2D line drawings. Our approach has three steps： （1） decomposing a complex line drawing into several simpler line drawings and transforming them into polyhedron; （2） reconstructing the 3D wireframe of curved object from these simpler line drawings and generating the curved faces; （3） combining the 3D objects into the complete objects. A number of examples are given to demonstrate the ability of our approach to successfully perform reconstruction of curved objects which are more complex than previous methods.

新疆于田Mw7.2地震3D同震形变场解算与分析

基于OKADA弹性半空间模型和差分干涉测量获取的升、降轨两种不同视角的同震形变场,分析了于田地震三维同震形变场特征。结果表明:在垂直方向上,断层西盘沉降,最大沉降形变量达-109.7 cm,东盘隆升,最大隆升形变量为19.2 cm;在东西方向上,断层西盘以朝西运动为主,最大形变量达-51.4 cm,东盘朝东运动,最大形变量达98.5 cm;在南北方向上,断裂西盘以朝南运动为主,最大形变量达-66.5 cm,断裂东盘朝北运动,最大形变量为25.8 cm;合成后的水平向形变表明,断层具有西盘朝南走滑、东盘朝北走滑的形变特征,揭示出于田地震断层为正断兼左旋走滑的破裂机制。

2-(3羧基-1-丙酰氨基)-2-脱氧-D-葡萄糖对人胃癌细胞系(SGC-7901)的诱导凋亡作用

目的 观察2-(3-羧基-1-丙酰氨基)-2-脱氧-D-葡萄糖(COADG)体外诱导人胃癌细胞(SGC-7901)凋亡的作用,探讨其可能作用机理。方法 采用MTT法,筛选药物作用最佳浓度。用流式细胞仪、琼脂糖凝胶电泳分析诱导凋亡前后的细胞DNA含量分析诱导凋亡前后的细胞DNA含量,透射电镜观察凋亡细胞的超微结构。结果2-(3-羧基-1-丙酰氨基)-2-脱氧-D-葡萄糖能明显抑制胃癌细胞的增长,MTT法显示抑制程度具有时间和剂量效应关系,统计组间比较差异有显著性;流式细胞仪分析可见亚二倍体(Sub-G1)凋亡峰;电镜观察到凋亡小体。结论2-(3-羧基-1-丙酰氨基)-2-脱氧-D-葡萄糖有诱导人胃癌细胞(SGC-7901)凋亡的作用。

地下圆形衬砌洞室对SH波的散射(Ⅰ):3-D级数解

针对地下圆形衬砌洞室对入射平面SH波的散射问题,采用波函数展开法,研究了不同频率入射波作用下,圆形衬砌洞室散射的三维级数解.结果表明:当入射波所在平面与圆形衬砌洞室Z轴互相垂直时,该级数解退化为半无限二维空间中的结果.级数解为定量研究圆形衬砌洞室对不同入射角度和入射波长下的SH波的散射引起的地震动的影响提供了理论依据.

柴胡皂苷D对人乳腺癌SK-BR-3细胞株增殖与凋亡的影响

目的:探讨柴胡皂苷D对人乳腺癌SK-BR-3细胞株增殖与凋亡的影响。方法:设置对照组、150 mg·L-1柴胡皂苷D组、100 mg·L-1柴胡皂苷D组、50 mg·L-1柴胡皂苷D组和25 mg·L-1柴胡皂苷D组,采用CCK-8实验方法检测柴胡皂苷D对人乳腺癌SK-BR-3细胞株增殖的影响;采用流式细胞术检测柴胡皂苷D对人乳腺癌细胞株SK-BR-3的细胞周期及细胞凋亡的影响。结果:柴胡皂苷D各浓度组细胞存活率分别为(85.3±4.13)%、(68.85±3.85)%、(45.28±3.25)%、(23.51±2.23)%,与对照组相比较,差异具有统计学意义(P<0.05)。柴胡皂苷D各浓度组G1期细胞比例分别为(58.23±2.21)%、(55.51±2.34)%、(45.67±3.23)%、(33.55±4.12)%,S期细胞的比例分别为(12.67±2.32)%、(10.34±2.45)%、(8.23±3.12)%、(7.34±3.98)%,G2期细胞所占的比例分别为(29.10±2.25)%、(34.15±3.45)%、(46.10±3.01)%、(59.11±2.34)%。柴胡皂苷D各浓度组G2期细胞所占比例与对照组比较,差异具有统计学意义(P<0.05)。柴胡皂苷D各浓度组细胞凋亡率分别为(9.00±1.35)%、(20.20±1.45)%、(38.50±2.50)%、(50.25±3.75)%,均高于对照组,差异具有统计学意义(P<0.05)。结论:柴胡皂苷D可明显阻滞SK-BR-3细胞株的增殖,将SK-BR-3细胞株的细胞周期阻滞于G2期,以促进该细胞的凋亡。

Evaluation of earthquake impact on magnitude of the minimum principal stress along a shotcrete lined pressure tunnel in Nepal

In situ stress condition in rock mass is influenced by both tectonic activity and geological environment such as faulting and shearing in the rock mass.This influence is of significance in the Himalayan region,where the tectonic movement is active,resulting in periodic dynamic earthquakes.Each large-scale earthquake causes both accumulation and sudden release of strain energy,instigating changes in the in situ stress environment in the rock mass.This paper first highlights the importance of the magnitude of the minimum principal stress in the design of unlined or shotcrete lined pressure tunnel as water conveyance system used for hydropower schemes.Then we evaluated the influence of local shear faults on the magnitude of the minimum principal stress along the shotcrete lined high pressure tunnel of Upper Tamakoshi Hydroelectric Project(UTHP)in Nepal.A detailed assessment of the in situ stress state is carried out using both measured data and three-dimensional(3D)numerical analyses with FLAC3D.Finally,analysis is carried out on the possible changes in the magnitude of the minimum principal stress in the rock mass caused by seismic movement(dynamic loading).A permanent change in the stress state at and nearby the area of shear zones along the tunnel alignment is found to be an eminent process.

A Novel Airborne 3D Laser Point Cloud Hole Repair Algorithm Considering Topographic Features

Hole repair processing is an important part of point cloud data processing in airborne 3-dimensional(3D)laser scanning technology.Due to the fragmentation and irregularity of the surface morphology,when applying the 3D laser scanning technology to mountain mapping,the conventional mathematical cloud-based point cloud hole repair method is not ideal in practical applications.In order to solve this problem,we propose to repair the valley and ridge line first,and then repair the point cloud hole.The main technical steps of the method include the following points:First,the valley and ridge feature lines are extracted by the GIS slope analysis method;Then,the valley and ridge line missing from the hole are repaired by the mathematical interpolation method,and the repaired results are edited and inserted to the original point cloud;Finally,the traditional repair method is used to repair the point cloud hole whose valley line and ridge line have been repaired.Three experiments were designed and implemented in the east bank of the Xiaobaini River to test the performance of the proposed method.The results showed that compared with the direct point cloud hole repair method in Geomagic Studio software,the average repair accuracy of the proposed method,in the 16 m buffer zone of valley line and ridge line,is increased from 56.31 cm to 31.49 cm.The repair performance is significantly improved.

Exploring Local Regularities for 3D Object Recognition

In order to find better simplicity measurements for 3D object recognition, a new set of local regularities is developed and tested in a stepwise 3D reconstruction method, including localized minimizing standard deviation of angles（L-MSDA）, localized minimizing standard deviation of segment magnitudes（L-MSDSM）, localized minimum standard deviation of areas of child faces （L-MSDAF）, localized minimum sum of segment magnitudes of common edges （L-MSSM）, and localized minimum sum of areas of child face （L-MSAF）. Based on their effectiveness measurements in terms of form and size distortions, it is found that when two local regularities： L-MSDA and L-MSDSM are combined together, they can produce better performance. In addition, the best weightings for them to work together are identified as 10% for L-MSDSM and 90% for L-MSDA. The test results show that the combined usage of L-MSDA and L-MSDSM with identified weightings has a potential to be applied in other optimization based 3D recognition methods to improve their efficacy and robustness.

ESTABLISHMENT OF A HUMAN B CELL LINE THAT RESPONDS SPECIFICALLY TO B CELL GROWTH FACTOR

A human B cell line （3D5） that responds specifically to B cell growth factor （BCGF） hasbeen developed by a sequence of Staphylococcus aureus Cowen I activation,EB virus im-mortalization,and cloning.Proliferative response to PHA-stimulated T cell supernatant（PHA-T-Sup） and nonresponsiveness to rIL-2 stimulation were factors used to screen positivecells.Phenotype analysis with a flow cytometer indicated that:1) 3D5 is a B cell line:100% of the cells were positive for B1 marker and 59% were positive for sIg,while T3and Mo 1 were negative:2) 3D5 is an activated B cell line:both Tac and 4F2 markersof activated （but not of resting） B cells were 100% positive:3) 3D5 expresses high molecularweight BCGF （HMW-BCGF） receptor-associated epitope BA5.3D5 cells proliferated inresponse to cpBCGF stimulation in a dose-dependent manner.HMW-BCGF also induced3D5 cells to proliferate.Interestingly.no proliferation could be detected in the presenceof rIL-2,rIL-4,or rIFN-r.The data show that 3D5 cells are specifically BCGF-responsiveB cells.Using 3D5 cells as target,BCGF activity was detected in crude BCGF preparationsedimented by 85% （NH4）2SO4 and chromatographed in a DEAE-Sephadex A-25 column fromPHA-T-Sup.T24 cell supernatant with B cell differentiation factor （BCDF） activity couldnot induce 3D5 cells to differentiate into immunoglobulin-secreting cells.

Optimization on the High Precision 3D Seismic Acquisition Parameters in Leijia Tight Sandstone Oil Area

The main targets of seismic exploration research in Leijia carbonatite tight sandstone oil area of Liaohe depression are thin reservoirs prediction and minor faults identification, which is one of the important representatives of complex exploration objects in Liaohe depression. High precision 3D seismic exploration has significantly improved the ability of thin reservoirs prediction and minor faults identification of this area. Reducing the cost of high precision 3D seismic exploration through optimizing the acquisition parameters is very important for the next step exploration and development of Liaohe depression and similar areas. Based on high precision 3D seismic acquisition data in Leijia tight sandstone oil area, multiple sub-geometries are obtained with different bin sizes, different folds, different aspect ratio, different line intervals by extracting receiver points and shot points, and PSTM processing is performed respectively, obtained PSTM datasets of the sub-geometries, extract time slices, amplitude slices along the layer, coherent slices and so on. We evaluate the data results of the sub-geometries from the aspects of signal-to-noise ratio, thin reservoirs resolution, acquisition footprint and so on. Considering the exploration cost and data effect of each sub-geometry, the optimal direction of the main parameters of high precision seismic exploration in Liaohe depression is put forward, and the acquisition effect of adjacent area by the optimized parameters is given.

高原环境3500t/d熟料线100%燃无烟煤生产的系统设计

在1 420 m海拔的贵州毕节江天水泥100%燃无烟煤工程设计中,对当地产无烟煤取样进行了燃烧特性研究分析,确定窑用无烟煤细度(R0.08mm)控制≤3%,分解炉用无烟煤细度(R0.08mm)控制≤2%。并重点对分解炉的形式与结构进行调整,控制分解炉系统煤粉停留时间约31.84 s;同时采用专用四通道窑头燃烧器、高效篦冷机和大窑门罩等措施,确保煤粉在窑炉内的快速完全燃烧。投产后,该生产线系统稳定,实现了优质高产运行。

SHOWREEL I Hold the Line（别挂机）

在这部来自荷兰导演和动画家Sem Assink的喜剧战争短片中，瞎子带领瞎子穿越一片满是灰尘的荒原，它通过2D背景和3D人物的混合达到了它的效果。

D-氨基葡萄糖衍生物诱导Eca-109细胞凋亡的机制

目的探讨2-(3-羧基-1-丙酰氨基)-2-脱氧-D-葡萄糖{2-[(3-carboxy-1-oxoprogy1)amino]-2-deoxy-D-Glucose,CO-PADG}诱导Eca-109细胞凋亡的机制。方法不同浓度COPADG作用于人食管癌Eca-109细胞24h,检测Eca-109细胞的抑制率、凋亡率、细胞内活性氧(reactive oxygen spe-cies,ROS)、线粒体跨膜电位。结果Eca-109细胞凋亡率与COPADG浓度呈正相关,r=1.0,P<0.01;Eca-109细胞线粒体膜电位水平与Eca-109细胞凋亡率相关,r=1.0,P<0.01;ROS水平与Eca-109细胞凋亡率呈正相关,r=1.0,P<0.01;ROS水平与Eca-109细胞线粒体膜电位水平呈负相关,r=1.0,P<0.01。结论COPADG可促进Eca-109细胞凋亡,提高Eca-109细胞内ROS水平,并降低线粒体膜电位。实验结果提示COPADG提高ROS,降低Eca-109细胞线粒体膜电位启动细胞凋亡通路促使Eca-109细胞凋亡,并且线粒体膜电位的下降是通过提高ROS实现的。