Iodine deficiency (ID) during early pregnancy has an adverse effect on children's psychomotor and motor function but the mechanism has not been clarified. Therefore, our aim was to study the effect of maternal marg...Iodine deficiency (ID) during early pregnancy has an adverse effect on children's psychomotor and motor function but the mechanism has not been clarified. Therefore, our aim was to study the effect of maternal marginal ID on cerebellar neurodevelopment and the underlying mechanism. After obtaining marginal ID rats, we examined interactions between Bergmann gila cells (BGs) and Purkinje cells (PCs) using immunofluorescence and expression of the glutamate transporter and receptor by western blot. Our results showed that marginal ID reduced the number of contacted points between BGs and PCs,展开更多
The interaction of iodine as an cr-acceptor with a synthetic ligand,benzene-1,3-disulfonylamid-kriptofix[22](BDSAK) as a π-donor has been investigated spectrophotometrically in chloroform(CHCl3) and dichlorometh...The interaction of iodine as an cr-acceptor with a synthetic ligand,benzene-1,3-disulfonylamid-kriptofix[22](BDSAK) as a π-donor has been investigated spectrophotometrically in chloroform(CHCl3) and dichloromethane(DCM) solutions.The results of mole ratio plots and Job's method show the stoichiometry of complexation I2/BDSAK is 1:1.Stability constants have been calculated in various temperatures and thermodynamic parameters have also been determined from the temperatures dependence of the stability constants by using van't Hoff equation.The results indicate the iodine complex with BDSAK is enthalpy stabilized but entropy destabilized.展开更多
Objective To investigate the effects of mild insufficient iodine intake on thyroid function and autoantibodies in pregnant women,and to provide a basis for scientific supplementation of iodine to pregnant women.Method...Objective To investigate the effects of mild insufficient iodine intake on thyroid function and autoantibodies in pregnant women,and to provide a basis for scientific supplementation of iodine to pregnant women.Methods From December 2015 to March 2016,Suixi County展开更多
基金supported by the National Natural Science Foundation of China[grant numbers 81102126]Important Platform of Science and Technology for the Universities in Liaoning Province[grant number 16010]Program for Liaoning Innovative Research Team in University[grant number LT2015028]
文摘Iodine deficiency (ID) during early pregnancy has an adverse effect on children's psychomotor and motor function but the mechanism has not been clarified. Therefore, our aim was to study the effect of maternal marginal ID on cerebellar neurodevelopment and the underlying mechanism. After obtaining marginal ID rats, we examined interactions between Bergmann gila cells (BGs) and Purkinje cells (PCs) using immunofluorescence and expression of the glutamate transporter and receptor by western blot. Our results showed that marginal ID reduced the number of contacted points between BGs and PCs,
文摘The interaction of iodine as an cr-acceptor with a synthetic ligand,benzene-1,3-disulfonylamid-kriptofix[22](BDSAK) as a π-donor has been investigated spectrophotometrically in chloroform(CHCl3) and dichloromethane(DCM) solutions.The results of mole ratio plots and Job's method show the stoichiometry of complexation I2/BDSAK is 1:1.Stability constants have been calculated in various temperatures and thermodynamic parameters have also been determined from the temperatures dependence of the stability constants by using van't Hoff equation.The results indicate the iodine complex with BDSAK is enthalpy stabilized but entropy destabilized.
文摘Objective To investigate the effects of mild insufficient iodine intake on thyroid function and autoantibodies in pregnant women,and to provide a basis for scientific supplementation of iodine to pregnant women.Methods From December 2015 to March 2016,Suixi County