Objective:The objective of this study is to explore the clinical effects of structured skin care plan of integrated Chinese and Western medicine in intervening elderly patients with incontinence-associated dermatitis(...Objective:The objective of this study is to explore the clinical effects of structured skin care plan of integrated Chinese and Western medicine in intervening elderly patients with incontinence-associated dermatitis(IAD).Materials and Methods:Totally,66 elderly patients with IAD were randomly divided into the experiment group(32 cases)and control group(34 cases).The control group was given routine nursing care,while the experiment group was given a structured skin care plan.The observational course was 2 weeks.The treatment efficiency and healing time were compared between the two groups.Results:After 2-week intervention,the total effective rate of the experiment group was higher than that of the control group(97.1%vs.78.1%,X^(2)=3.913,P=0.048).The skin assessment tool score of the experiment group was lower than that of the control group(0.56±1.58 vs.1.75±2.46,Z=−−2.401,P=0.016).The healing time of the experiment group was shorter than that of the control group(7.29±4.76 days vs.10.69±6.36 days,Z=−2.280,P=0.026).Conclusion:The structured skin care plan of integrated Chinese and Western medicine showed a good effect in elderly IAD patients,and provided a reference for clinical treatment and care of elderly patients with IAD.展开更多
Objective:To discuss the specific application of Zhuang Medicine Crystal Sugar Ye'An Decoction in senile skin pruritus and its effects on serum IgE detection level.Methods:90 patients with senile skin pruritus adm...Objective:To discuss the specific application of Zhuang Medicine Crystal Sugar Ye'An Decoction in senile skin pruritus and its effects on serum IgE detection level.Methods:90 patients with senile skin pruritus admitted to our hospital from February 2019 to April 2020 were randomly grouped.The general treatment effect,itching,secondary skin lesion severity,sernum IL-6,IgE level and adverse reactions between 45 patients treated with Chlorcyclizine Hydrochloride Tablets(The control group)and 45 patients treated with Crystal Sugar Ye'An Decoction were compared.Results:The total effective rate of the treatment in the observation group was 93.33%,much higher than that in the control group,75.56%.The difference was verified and statistically significant(P<0.05).Before the treatment,the itching area,frequency,duration and severity of secondary skin lesions were at the same level(P>0.05).After the treatment,the above data were all reduced,and the reduction of the observation group was more significant than that of the control group,indicating the difference was statistically significant(P<0.05).Before the treatment,there was no difference in serum IL-6 and IgE test data between the two groups(P>0.05).After the treatment,the tendency all declined,and that of the observation group was more obvious,indicating the difference was statistically significant(P<0.05).During the experiment,no obvious adverse reactions were observed in both groups.Conclusion:In the treatment of patients with senile pruritus,the application of Zhuang Medicine Crystal Sugar Ye’An Decoction is not only safe and reliable,but can promote the improvement of patients'symptoms,adjust the level of inflammatory factors,and enhance clinical efficacy.展开更多
Objective:This study aimed to evaluate the influence of advanced glycation end-product(AGE)accumulation on the prevalence and severity of overactive bladder(OAB)in community-dwelling elderly adults.Methods:We conducte...Objective:This study aimed to evaluate the influence of advanced glycation end-product(AGE)accumulation on the prevalence and severity of overactive bladder(OAB)in community-dwelling elderly adults.Methods:We conducted a cross-sectional study involving 269 Japanese community dwellers aged≥75 years in 2015.AGE accumulation was non-invasively measured via skin autofluorescence(SAF)values using AGE Reader.The primary and secondary outcomes were the presence and severity of OAB evaluated using the Overactive Bladder Symptom Score(OABSS).Individuals with an urgency score of≥2 and sum score of≥3 were considered to have OAB.The associations of SAF with the prevalence and severity of OAB were assessed using logistic and linear regression models,respectively,adjusted for clinically important confounders.Results:The median age of participants was 78 years.Of 269 participants,110(40.9%)were men and 75(27.9%)had OAB.The median SAF was 2.2 arbitrary units(AUs).Increasing median SAF was observed with increasing age.Multivariable analysis revealed that SAF was not associated with either the likelihood of having OAB(odds ratio per AU=0.77,95%confidence interval:0.37-1.62)or the natural log-transformed OABSS(0 per AU=-0.07,95%confidence interval:-0.26-0.12).Conclusions:In this study,AGE accumulation,as assessed by SAF,was not associated with the prevalence and severity of OAB in Japanese community-dwelling elderly people aged≥75 years.展开更多
目的通过系统评价和Meta分析明确维持性血液透析(maintenance hemodialysis,MHD)患者皮肤瘙痒的影响因素。方法检索PubMed、Web of Science、CINAHL、Medline、Embase、Cochrane of Library、中国知网、万方数据知识服务平台、维普中文...目的通过系统评价和Meta分析明确维持性血液透析(maintenance hemodialysis,MHD)患者皮肤瘙痒的影响因素。方法检索PubMed、Web of Science、CINAHL、Medline、Embase、Cochrane of Library、中国知网、万方数据知识服务平台、维普中文期刊服务平台、中国生物医学文献数据库,检索时间为建库至2024年2月。由2名研究员独立筛选文献、提取资料及评价偏倚风险后,采用Stata 18.0对MHD患者皮肤瘙痒的影响因素进行Meta分析,其余影响因素进行描述性分析。结果共纳入14篇文献,涉及5285例病例,共计30项影响因素,归纳为社会人口学因素和疾病相关因素2个主题。Meta分析结果显示:C反应蛋白(OR=1.44,95%CI:1.04~2.00)为MHD患者皮肤瘙痒的影响因素(P<0.05);血磷(OR=1.75,95%CI:1.02~2.99)为相关因素(P<0.05)。结论MHD患者发生皮肤瘙痒的原因复杂,受研究数量和质量的限制,其他影响因素仍需高质量的研究予以验证。展开更多
基金This study is supported by the Young Teacher Project of Beijing University of Chinese Medicine(No.:2018-JYB-JS134).
文摘Objective:The objective of this study is to explore the clinical effects of structured skin care plan of integrated Chinese and Western medicine in intervening elderly patients with incontinence-associated dermatitis(IAD).Materials and Methods:Totally,66 elderly patients with IAD were randomly divided into the experiment group(32 cases)and control group(34 cases).The control group was given routine nursing care,while the experiment group was given a structured skin care plan.The observational course was 2 weeks.The treatment efficiency and healing time were compared between the two groups.Results:After 2-week intervention,the total effective rate of the experiment group was higher than that of the control group(97.1%vs.78.1%,X^(2)=3.913,P=0.048).The skin assessment tool score of the experiment group was lower than that of the control group(0.56±1.58 vs.1.75±2.46,Z=−−2.401,P=0.016).The healing time of the experiment group was shorter than that of the control group(7.29±4.76 days vs.10.69±6.36 days,Z=−2.280,P=0.026).Conclusion:The structured skin care plan of integrated Chinese and Western medicine showed a good effect in elderly IAD patients,and provided a reference for clinical treatment and care of elderly patients with IAD.
基金National Key R&D Program(N0:2017YFC1703903)Youth Fund Project of Guangxi First-Class Discipline Construction Projects(No.2019XK048)+2 种基金General Project of Guangxi First-Class Discipline Construction Projects(No.:Guijiao Scientific Research 2019XK043)Guangxi First-Class Discipline Construction Projects(No.:Gui Education Scientific Research[2018]12)The High-Level Talent Team Cultivation Project of Qihuang Engineering of the Guangxi University of Chinese Medicine(No.2018005)。
文摘Objective:To discuss the specific application of Zhuang Medicine Crystal Sugar Ye'An Decoction in senile skin pruritus and its effects on serum IgE detection level.Methods:90 patients with senile skin pruritus admitted to our hospital from February 2019 to April 2020 were randomly grouped.The general treatment effect,itching,secondary skin lesion severity,sernum IL-6,IgE level and adverse reactions between 45 patients treated with Chlorcyclizine Hydrochloride Tablets(The control group)and 45 patients treated with Crystal Sugar Ye'An Decoction were compared.Results:The total effective rate of the treatment in the observation group was 93.33%,much higher than that in the control group,75.56%.The difference was verified and statistically significant(P<0.05).Before the treatment,the itching area,frequency,duration and severity of secondary skin lesions were at the same level(P>0.05).After the treatment,the above data were all reduced,and the reduction of the observation group was more significant than that of the control group,indicating the difference was statistically significant(P<0.05).Before the treatment,there was no difference in serum IL-6 and IgE test data between the two groups(P>0.05).After the treatment,the tendency all declined,and that of the observation group was more obvious,indicating the difference was statistically significant(P<0.05).During the experiment,no obvious adverse reactions were observed in both groups.Conclusion:In the treatment of patients with senile pruritus,the application of Zhuang Medicine Crystal Sugar Ye’An Decoction is not only safe and reliable,but can promote the improvement of patients'symptoms,adjust the level of inflammatory factors,and enhance clinical efficacy.
基金supported by a Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research(KAKENHI)[Grant No.JP18K09975].
文摘Objective:This study aimed to evaluate the influence of advanced glycation end-product(AGE)accumulation on the prevalence and severity of overactive bladder(OAB)in community-dwelling elderly adults.Methods:We conducted a cross-sectional study involving 269 Japanese community dwellers aged≥75 years in 2015.AGE accumulation was non-invasively measured via skin autofluorescence(SAF)values using AGE Reader.The primary and secondary outcomes were the presence and severity of OAB evaluated using the Overactive Bladder Symptom Score(OABSS).Individuals with an urgency score of≥2 and sum score of≥3 were considered to have OAB.The associations of SAF with the prevalence and severity of OAB were assessed using logistic and linear regression models,respectively,adjusted for clinically important confounders.Results:The median age of participants was 78 years.Of 269 participants,110(40.9%)were men and 75(27.9%)had OAB.The median SAF was 2.2 arbitrary units(AUs).Increasing median SAF was observed with increasing age.Multivariable analysis revealed that SAF was not associated with either the likelihood of having OAB(odds ratio per AU=0.77,95%confidence interval:0.37-1.62)or the natural log-transformed OABSS(0 per AU=-0.07,95%confidence interval:-0.26-0.12).Conclusions:In this study,AGE accumulation,as assessed by SAF,was not associated with the prevalence and severity of OAB in Japanese community-dwelling elderly people aged≥75 years.
文摘目的通过系统评价和Meta分析明确维持性血液透析(maintenance hemodialysis,MHD)患者皮肤瘙痒的影响因素。方法检索PubMed、Web of Science、CINAHL、Medline、Embase、Cochrane of Library、中国知网、万方数据知识服务平台、维普中文期刊服务平台、中国生物医学文献数据库,检索时间为建库至2024年2月。由2名研究员独立筛选文献、提取资料及评价偏倚风险后,采用Stata 18.0对MHD患者皮肤瘙痒的影响因素进行Meta分析,其余影响因素进行描述性分析。结果共纳入14篇文献,涉及5285例病例,共计30项影响因素,归纳为社会人口学因素和疾病相关因素2个主题。Meta分析结果显示:C反应蛋白(OR=1.44,95%CI:1.04~2.00)为MHD患者皮肤瘙痒的影响因素(P<0.05);血磷(OR=1.75,95%CI:1.02~2.99)为相关因素(P<0.05)。结论MHD患者发生皮肤瘙痒的原因复杂,受研究数量和质量的限制,其他影响因素仍需高质量的研究予以验证。
