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具有POLE致病性突变子宫内膜癌的临床病理及分子特征分析
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作者 蔡宇梦 周杨 +4 位作者 汪昊 庞钧译 吴焕文 师晓华 梁智勇 《诊断病理学杂志》 2024年第4期282-286,322,共6页
目的探讨具有POLE致病性突变子宫内膜癌(EC)的临床病理及分子特征。方法选取179例EC患者,根据POLE基因突变、错配修复(MMR)蛋白表达及p53表达/TP53突变进行分子分型,分析POLE mut型EC的临床病理及分子特征。结果POLE mut20例,MMRd 48例,... 目的探讨具有POLE致病性突变子宫内膜癌(EC)的临床病理及分子特征。方法选取179例EC患者,根据POLE基因突变、错配修复(MMR)蛋白表达及p53表达/TP53突变进行分子分型,分析POLE mut型EC的临床病理及分子特征。结果POLE mut20例,MMRd 48例,NSMP 90例,p53 abn 21例。POLE mut EC多为FIGOⅠ期(17/20),中-低分化子宫内膜样癌(EEC)(13/20)、局限于内膜/浅肌层(17/20)、肿瘤浸润性淋巴细胞(TILs)显著(17/20)、无/局灶(LVSI)(18/20)、无淋巴结转移(19/20)。4个亚组间临床病理特征的差异均有统计学意义(P<0.05)。POLE mut型预后最好,具有多重分类特征的病例预后更接近POLE mut型。结论POLE mut EC提示着较高的组织学分级,较早的临床分期及较好的预后;POLE mut可继发dMMR/MSI-H表型及p53/TP53异常,应归类为POLE mut型。 展开更多
关键词 子宫内膜癌 分子分型 pole 错配修复缺陷 TP53
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Design and Evaluation of a Consequent Pole K-shaped Permanent Magnet Motor for Outboard Application Using a Hybrid Mathematical Model
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作者 Mehrage Ghods Jawad Faiz Hamed Gorginpour 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第4期379-393,共15页
Nowadays,there is considerable research interest in proposing modern permanent magnet(PM)electric machine structures for applications such as electric vehicles.Several radial and axial topologies with different arrang... Nowadays,there is considerable research interest in proposing modern permanent magnet(PM)electric machine structures for applications such as electric vehicles.Several radial and axial topologies with different arrangements of PM in the stator and rotor have been introduced for PM Vernier motors(PMVM)with the aim of increasing the performance characteristics such as power factor,efficiency,rotational torque torque density and wider constant torque-speed region.Meanwhile,the spoke PM arrangement has provided higher torque density than the surface and V-shaped arrangement.But in contrast,the V-shaped arrangement has a more sinusoidal flux and less cogging torque.In this paper,a 620 W,12-slot 16-pole Vernier PM motor with a fractional slot arrangement.Consequent K-shaped pole is introduced,which has the advantages of spoke and V-shaped magnetic arrangements.After presenting and confirming the concept of the proposed structure based on functional comparison with conventional structures,an analytical modeling based on the harmonic analysis method is introduced to accurately predict the performance of the machine,and finally the proposed structure is prototyped and the experimental results are simulated and modeling are compared. 展开更多
关键词 Non-linear harmonic model Conformal mapping Magnetic saturation Consequent pole K-shaped Vernier PM Machine Flux-modulation effects
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Effectiveness of Chromated Copper Arsenate against Deteriorating Agents of Eucalyptus Poles and Posts in Four Eco-Regions in Kenya
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作者 Miriam Gathogo Evanson Omuse George Muthike 《Open Journal of Forestry》 2024年第3期281-296,共16页
Previous studies done elsewhere have shown that Eucalyptus poles treated with chromated copper arsenate (CCA) can last over 30 years. Kenya is exceptional because in some eco-regions, the Eucalyptus poles’ life span ... Previous studies done elsewhere have shown that Eucalyptus poles treated with chromated copper arsenate (CCA) can last over 30 years. Kenya is exceptional because in some eco-regions, the Eucalyptus poles’ life span has greatly reduced to 5 years. The current study was designed to evaluate wood deteriorating agents of CCA-treated Eucalyptus poles and variability in four eco-regions of Kenya, namely, dryland, coastal, highland and humid lake. A total of 360 Eucalyptus pole samples were used for this experiment. Three CCA treatments were used to treat transmission poles at 20 kg/cm3 fencing posts samples at 6 kg/cm3, and a control group. Results indicated that termites and wood-decay fungi attacks caused wood deterioration in the four eco-regions. The proportion of power transmission pole degradation by wood deteriorating agents varied across eco-regions, between treatments and control and between time after treatments. Dryland eco-regions had the highest termite-related degradation (41.82%) while wood-decay fungi attack was highest in the highland eco-regions (9.20%). Samples treated with 6 kg/cm3 recorded the lowest level of wood deterioration, manifested by minimal superficial termite and wood-decay fungi attack. Samples treated with 20 kg/cm3 were characterized by moderate termite and wood-decay fungi attacks observed around the heartwood region, unlike sapwood. This study concluded that the deterioration of Eucalyptus CCA-treated poles is a question of climatic variability and hence, to increase the poles’ lifespan, CCA treatment should be tailored according to the characteristics of the ecoregion of use. Further investigations will inform the diversity of termites and decay-fungi across different eco-regions. 展开更多
关键词 Wood Deteriorating Agents CCA Transmission poles Wood-Decay Fungi
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Study on the Effect of Magnetic Pole Clipping Angle on the Eddy Current Loss of Permanent Magnets in the Rotor of Magnetically Levitated Permanent Magnet Synchronous High-Speed Electric Spindles
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作者 Xiangjun Shen Houcai Liu +2 位作者 Huimin Kang Ruirong He Jiale Xi 《Open Journal of Applied Sciences》 2024年第11期3261-3281,共21页
Aiming at the problem of high temperature and even demagnetization failure of permanent magnet (PM) due to PM eddy current loss in PM synchronous high-speed motors, this paper proposes a technique to lessen PM eddy cu... Aiming at the problem of high temperature and even demagnetization failure of permanent magnet (PM) due to PM eddy current loss in PM synchronous high-speed motors, this paper proposes a technique to lessen PM eddy current loss by cutting the angle of PM poles to change the shape of PM structure. Firstly, an analysis is conducted on the mechanism of PM synchronous high-speed motor eddy current loss production, the theoretical analytical model of PM eddy current loss is deduced, and it is theoretically proved that the magnetic pole shaving angle can reduce PM eddy current loss. Then, a 25 KW surface-type PM synchronous high-speed motor as an object, using two-dimensional time-step finite element method (FEM) to model and analyze PM eddy current loss. The results show that the smaller the PM pole shaving angle, the less its eddy current loss will be, it is possible to minimize the pole shaving angle of eddy current loss by 9.8% compared to the unshaved angle. Finally, the temperature field of the PM is calculated using a finite element method, and the outcomes demonstrate that the maximum temperature of the PM with a magnetic pole shaving angle can be reduced by about 5% compared with the unshaved angle. 展开更多
关键词 Magnetic pole Clipping Permanent Magnet (PM) Eddy Current Loss Temperature Field Two-Dimensional Time-Stepped Finite Element Method (FEM)
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Research on the Mechanical Analysis of Run-Up Speed in Pole Vaulting and the Application of Key Auxiliary Training Methods
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作者 Qin Xia 《Journal of Educational Theory and Management》 2024年第4期82-86,共5页
Analyzing from the perspective of physics mechanics,the pole vault is a project which transforms kinetic energy into elastic potential energy.The magnitude of kinetic energy depends on the vaulter’s approaching speed... Analyzing from the perspective of physics mechanics,the pole vault is a project which transforms kinetic energy into elastic potential energy.The magnitude of kinetic energy depends on the vaulter’s approaching speed,while the magnitude of elastic potential energy depends on height.Therefore,the run-up speed determines the vaulter’s performance in pole vault to a certain extent.the horizontal speed of the pole-holding approach phase transitioning into vertical upward speed plays a crucial role in executing pole vault techniques,and the model of approaching speed establishes a theoretical foundation for vaulters to break through the pole limitation.In terms of specialized technical assistance in speed training,short-distance speed exercises are used in the approaching phase;in the swinging phase,gymnastic rings,single bar and suspension rope exercises are employed for suspension;in the stretch phase,trampoline exercises play a important role in rotation phase,etc. 展开更多
关键词 pole vault techniques Run-up speed model Training techniques
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采用提篮钢板技术治疗粉碎性髌骨下极骨折的疗效分析
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作者 齐巍 高烁 +1 位作者 王一兵 周力 《骨科临床与研究杂志》 2025年第1期26-31,共6页
目的探讨应用提篮钢板技术治疗粉碎性髌骨下极骨折的临床疗效。方法回顾性分析唐山市第二医院创伤一科2021年3月至2024年3月应用提篮钢板技术治疗的18例粉碎性髌骨下极骨折患者的临床资料,其中男10例,女8例,年龄21~73(44.1±14.2)岁... 目的探讨应用提篮钢板技术治疗粉碎性髌骨下极骨折的临床疗效。方法回顾性分析唐山市第二医院创伤一科2021年3月至2024年3月应用提篮钢板技术治疗的18例粉碎性髌骨下极骨折患者的临床资料,其中男10例,女8例,年龄21~73(44.1±14.2)岁;左膝7例,右膝11例;交通伤8例,摔伤10例。应用提篮钢板技术治疗粉碎性髌骨下极骨折。住院期间观察记录患者年龄、性别、术前疼痛评分(FPS-R)。患者出院后于术后6周、8周、10周、12周、6个月、12个月门诊复查随访,记录骨折愈合时间、膝关节屈曲康复时间、末次随访FPS-R,末次随访B?stman髌骨骨折疗效评分。结果18例患者术前FPS-R评分6(4,6)分,切口均一期愈合,无失访患者;随访时间6~12个月;骨折愈合时间8(6,8.5)周;膝关节屈曲康复时间:90°需3(3,4)周,120°需6(6,8)周,全范围需10(8,10)周;末次随访FPS-R评分2(0,2)分;末次随访B?stman髌骨骨折疗效评分29(28,30)分,优17例,良1例,优良率为100%。18例患者骨折愈合良好,未出现感染、切口愈合不良、内固定物失效、内固定激惹等并发症。结论应用提篮钢板技术治疗粉碎性髌骨下极骨折疗效确切、满意。该技术可达到骨折坚强内固定、早期功能锻炼的目的,术后并发症少,骨折愈合率高,膝关节功能恢复好,疗效优良率高。该技术内固定材料获取容易,手术技术简单,适合在基层医院推广应用。 展开更多
关键词 骨折固定术 骨固定钢丝 髌骨下极骨折 微型接骨板
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交替极径向磁力联轴器的磁热耦合分析
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作者 田杰 余浩 董刚 《机械工程师》 2025年第1期1-3,11,共4页
为研究交替极径向磁力联轴器在运行时各部件的温度分布状况,在理论分析的基础上,确定了该磁力联轴器的热源、导热系数及散热系数。通过有限元分析软件对其进行了温度场分析,得到了交替极径向磁力联轴器整体及各部件的温度分布状况,为该... 为研究交替极径向磁力联轴器在运行时各部件的温度分布状况,在理论分析的基础上,确定了该磁力联轴器的热源、导热系数及散热系数。通过有限元分析软件对其进行了温度场分析,得到了交替极径向磁力联轴器整体及各部件的温度分布状况,为该类型磁力联轴器的设计奠定了一定的基础。 展开更多
关键词 交替极磁力联轴器 温度场 磁热耦合
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POLE突变在肿瘤发生发展中的作用 被引量:6
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作者 黄茜 张声 《临床与病理杂志》 2015年第12期2173-2179,共7页
POLE为DNA聚合酶的催化亚基,具有5'3'DNA聚合酶活性和3'→5'核酸外切酶活性,对DNA复制和校正具有重要作用。POLE突变将引起校正功能缺失,可能导致肿瘤发生。近年来,TCGA在多种肿瘤中检出POLE突变,POLE突变的肿瘤以其独... POLE为DNA聚合酶的催化亚基,具有5'3'DNA聚合酶活性和3'→5'核酸外切酶活性,对DNA复制和校正具有重要作用。POLE突变将引起校正功能缺失,可能导致肿瘤发生。近年来,TCGA在多种肿瘤中检出POLE突变,POLE突变的肿瘤以其独特超强突变分子表型及良好的预后成为近期研究热点。本文综述POLE的结构、功能及其突变在肿瘤发生发展中的作用的研究进展。 展开更多
关键词 pole 肿瘤 预后
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South Pole温度风速廓线的统计分析 被引量:1
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作者 汪平 吴晓庆 《大气与环境光学学报》 CAS 2013年第5期334-343,共10页
利用2008年South Pole的探空资料,通过大气温度和风速廓线,确定了South Pole地区冬季(6,7,8月)和夏季(12,1,2月)的大气边界层结构、边界层和对流层顶的高度。对近地面的温度、水汽压、风速和风向进行了统计分析。结果表明,South Pole大... 利用2008年South Pole的探空资料,通过大气温度和风速廓线,确定了South Pole地区冬季(6,7,8月)和夏季(12,1,2月)的大气边界层结构、边界层和对流层顶的高度。对近地面的温度、水汽压、风速和风向进行了统计分析。结果表明,South Pole大气边界层大多时候为稳定型,但在夏季也存在不稳定的情况,尤其在1月份较多;夏季夜晚的边界层平均高度为389 m,比白天的304 m大,冬季夜晚的边界层平均高度为591 m,大于夏季夜晚;夏季白天对流层顶平均高度比夜晚略大,分别为6172 m和5770m。South Pole高层大气理查森数的倒数基本都小于4,发生湍流的可能性很小。 展开更多
关键词 SOUTH pole 温度风速廓线 边界层顶 对流层顶
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交流绕组设计过程的画分连三步曲
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作者 程小华 《防爆电机》 2025年第1期16-18,29,共4页
把交流绕组设计过程归纳为“画分连”三步曲(画图、分带、连端),表述精炼,便于操作,便于记忆。并提出了多匝线圈的等价画法。同时指出,设计交流绕组时,星形图不是必需的。
关键词 交流绕组设计 画分连三步曲 星形图 展开图 切割图 槽距电角 极相带
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Rugged Resonant Pole and Its Applications in Soft-Switching Converter
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作者 肖岚 严仰光 《Journal of Southeast University(English Edition)》 EI CAS 2002年第3期225-232,共8页
The soft switching operation principle and operation performance of rugged resonant pole (RRP) is given. The applications of RRP in soft switching DC DC converter and soft switching inverter are discussed in detail. R... The soft switching operation principle and operation performance of rugged resonant pole (RRP) is given. The applications of RRP in soft switching DC DC converter and soft switching inverter are discussed in detail. RRP can constitute buck boost soft switching DC DC converter and isolated soft switching DC DC converter with the automatic limitation performance of output power. Partial series resonant DC DC converter with RRP can realize the zero voltage/zero current switching of power devices. RR... 展开更多
关键词 rugged resonant pole soft switching DC DC converter INVERTER
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基于某车型Euro NCAP侧面柱碰胸压性能研究分析
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作者 周晓雷 董伟 +2 位作者 王刚刚 李文杰 王坤 《汽车实用技术》 2025年第1期90-96,共7页
文章基于某款新能源车型按欧盟新车评价规程(Euro NCAP)进行的整车安全性能开发,对侧柱碰工况的胸压问题进行的性能研究,通过胸压问题的理论研究得出影响因子,并采用有限元仿真分析、滑台试验和整车碰撞验证结合的研究方式,提出车身结... 文章基于某款新能源车型按欧盟新车评价规程(Euro NCAP)进行的整车安全性能开发,对侧柱碰工况的胸压问题进行的性能研究,通过胸压问题的理论研究得出影响因子,并采用有限元仿真分析、滑台试验和整车碰撞验证结合的研究方式,提出车身结构、气囊包型、座椅发泡设计等的优化方案,最终提升了整车碰撞安全性能。研究表明,乘员的安全空间、气囊对假人安全约束、座椅状态的稳定性等都对胸压性能产生影响,据此提出的方案最后通过实车碰撞试验验证了优化方案的可行性。 展开更多
关键词 侧柱碰 胸压性能 Euro NCAP 气囊 座椅
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H37地极坐标序列的低频变化及其与POLE95相应结果的比较 被引量:1
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作者 廖德春 《中国科学院上海天文台年刊》 1997年第18期34-40,共7页
利用依巴谷暂定星表(H37)为统一参考架解算出的地极坐标序列和POLE95序列,分析了地极坐标的长期变化、Markowitz变化和其它低频变化。从两个序列得到他极移动长期漂移速度的平均值为3.86mas/yr,方向为西经82°.7;对Markowit... 利用依巴谷暂定星表(H37)为统一参考架解算出的地极坐标序列和POLE95序列,分析了地极坐标的长期变化、Markowitz变化和其它低频变化。从两个序列得到他极移动长期漂移速度的平均值为3.86mas/yr,方向为西经82°.7;对Markowitz波动的分析表明,其周期约为25~30年,周期和振幅的变化程度分别为10%和40%。 展开更多
关键词 地极坐标 地极移动 长期极移 依巴谷暂定星表 漂移速度
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基于South Pole站和McMurdo站的极区电离层闪烁统计特性 被引量:2
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作者 李鹏辉 胡红桥 +2 位作者 方涵先 刘瑞源 杨升高 《极地研究》 CAS CSCD 2016年第1期19-24,共6页
利用South Pole和Mc Murdo两站2013年12月至2014年11月期间的电离层相位闪烁数据,统计分析了两站电离层相位闪烁发生率的周日分布和季节分布。统计结果表明,两站的相位闪烁发生率在季节分布上,春秋季明显大于夏冬季;在周日分布上呈双峰... 利用South Pole和Mc Murdo两站2013年12月至2014年11月期间的电离层相位闪烁数据,统计分析了两站电离层相位闪烁发生率的周日分布和季节分布。统计结果表明,两站的相位闪烁发生率在季节分布上,春秋季明显大于夏冬季;在周日分布上呈双峰结构。在磁中午附近和磁子夜后有较大的闪烁发生率。磁中午附近是因为极隙区的软电子沉降和电离层对流导致的电离层不均匀性,造成较强的无线电波闪烁;磁子夜附近闪烁增强可能是穿越极盖区的等离子体云破碎造成较大密度梯度导致。总体上说,Mc Murdo站的闪烁发生率高于South Pole站,这可能是因为它们所处的磁纬不同所致。 展开更多
关键词 SOUTH pole McMurdo站 极区电离层 相位 闪烁发生率
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Mach-Zehnder Electro-Optic Polymer Modulator with C orona Poled Core Layer 被引量:3
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作者 杨晓红 杜云 +1 位作者 石志文 吴荣汉 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2001年第8期971-974,共4页
A Mach-Zehnder(MZ) electro-optic(EO) modulator are real iz ed,with three optical layers as polymer materials.The functional layer is the co rona poled crosslinkable polyurethane.The ridge waveguide is fabricated by us... A Mach-Zehnder(MZ) electro-optic(EO) modulator are real iz ed,with three optical layers as polymer materials.The functional layer is the co rona poled crosslinkable polyurethane.The ridge waveguide is fabricated by using the spin-coating,poling,photolithography and oxygen reactive ion etching(RIE) techniques.The mode and the modulation properties of these devices are demonstra ted in a micron control system,while the light source works at the wavelength of 1 31 or 1 55 micron. 展开更多
关键词 poled polymer M Z waveguide electro-optic modulator
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基于粘合棚杆地膜的小拱棚铺膜机的设计与实验
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作者 陈建东 张山鹰 李峰 《农机化研究》 北大核心 2025年第2期81-85,90,共6页
旨在为小拱棚铺膜机的研发提供了一种新的研究方向与思路。设计时,使用一种带棚杆的复合地膜,即将棚杆按一定间隔事先粘接在地膜上,制作成一种特殊的地膜。这种地膜在铺膜机鸭嘴式拱形模具的压制下,将棚杆与地膜一起从鸭嘴式拱形模具中... 旨在为小拱棚铺膜机的研发提供了一种新的研究方向与思路。设计时,使用一种带棚杆的复合地膜,即将棚杆按一定间隔事先粘接在地膜上,制作成一种特殊的地膜。这种地膜在铺膜机鸭嘴式拱形模具的压制下,将棚杆与地膜一起从鸭嘴式拱形模具中拉出并压入地膜两边开好的沟槽中,再经覆土、压实,完成小拱棚铺设工作。这种铺设方法的优点是铺设机械设备简单、价格低、铺设过程中棚杆的间距恒定、棚杆与地膜入土深度稳定、铺设过程能实现连续高效作业、铺设质量稳定,且操作简单、安全可靠;缺点是地膜与铺膜机必需是专用的、通用性差。 展开更多
关键词 小拱棚 铺膜机 粘合棚杆地膜
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系统极点数量与位置变化对系统性能的影响
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作者 石璐瑶 张衡 +1 位作者 臧程成 张凤婷 《自动化应用》 2025年第1期40-42,共3页
为探讨极点数量与位置变化对系统性能的影响,在已有系统函数上增加极点或改变极点位置,观察系统在时域、频域以及根轨迹曲线的变化,分析系统在不同域的性能指标随极点数量和位置的变化。在时域分析中,改变系统极点数量和极点位置,观察... 为探讨极点数量与位置变化对系统性能的影响,在已有系统函数上增加极点或改变极点位置,观察系统在时域、频域以及根轨迹曲线的变化,分析系统在不同域的性能指标随极点数量和位置的变化。在时域分析中,改变系统极点数量和极点位置,观察系统阶跃响应曲线变化,分析系统动态性能参数随极点数量、位置变化的规律。在频域分析中,改变系统极点数量和极点位置,观察Nyquist曲线和Bode图的变化,分析稳定裕度随极点数量、位置变化的规律。通过观察极点数量、位置变化在不同域呈现的变化特点,分析极点对系统性的影响规律,为设计和优化系统提供了重要的参考依据和理论支持。 展开更多
关键词 MATLAB 极点 时域分析法 频域分析法
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Improvement of Electrochemical Machining Accuracy by Using Dual Pole Tool 被引量:10
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作者 ZHU Di, XU Hui-yu (Department of Mechanical Engineering, Nanjing University of Aeronaut ics & Astronautics, Nanjing 210016, China) 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2002年第S1期118-,共1页
Electrochemical machining (ECM) is one of the best al ternatives for producing complex shapes in advanced materials used in aircraft a nd aerospace industries. However, the reduction of the stray material removal co n... Electrochemical machining (ECM) is one of the best al ternatives for producing complex shapes in advanced materials used in aircraft a nd aerospace industries. However, the reduction of the stray material removal co ntinues to be major challenges for industries in addressing accuracy improvement . This study presents a method of improving machining accuracy in ECM by using a dual pole tool with a metallic bush outside the insulated coating of a cathode tool. The bush is connected with anode and so the electric field at the side gap area is substantially weakened. The modeling and simulation indicate that the p ositive bush brings down the current density at the side gap area of the machine d hole and hence reduces the stray material removal there. It has been experimen tally observed that the machining accuracy and the process stability are signifi cantly improved. 展开更多
关键词 electrochemical machining dual pole tool accura cy
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Pole基因在子宫内膜癌中的研究进展 被引量:2
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作者 王蒙蒙 张丽华 《诊断病理学杂志》 2021年第7期582-584,共3页
2013年美国癌症基因组图谱(TCGA)提出依据分子改变将子宫内膜癌分为Pole突变型,MSI(微卫星不稳定)高突变型,高拷贝数型,低拷贝数型。其中,pole基因突变型具有形态学高度恶性,但具有较好预后,对免疫抑制剂反应良好的临床病理特征,同时pol... 2013年美国癌症基因组图谱(TCGA)提出依据分子改变将子宫内膜癌分为Pole突变型,MSI(微卫星不稳定)高突变型,高拷贝数型,低拷贝数型。其中,pole基因突变型具有形态学高度恶性,但具有较好预后,对免疫抑制剂反应良好的临床病理特征,同时pole基因突变可能与合并多个基因突变的子宫内膜癌有关,因此认识和了解pole基因突变与子宫内膜癌的关系非常重要。另外,对于pole突变合并P53,或者错配修复蛋白基因突变以及P53和错配修复蛋白基因同时突变,或者三个基因同时发生突变时,pole基因与其他基因的相互作用本文将复习文献,对pole基因突变的子宫内膜癌中研究进展进行综述。 展开更多
关键词 pole基因 子宫内膜癌 分子分型
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Retrograde intrarenal surgery vs miniaturized percutaneous nephrolithotomy to treat lower pole renal stones 1.5-2.5 cm in diameter 被引量:7
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作者 Mao-Mao Li Hou-Meng Yang +2 位作者 Xiao-Ming Liu Hong-Gang Qi Guo-Bin Weng 《World Journal of Clinical Cases》 SCIE 2018年第15期931-935,共5页
AIM To compare the outcomes of retrograde intrarenal surgery(RIRS) and miniaturized percutaneous nephrolithotomy(mini-PCNL) in treating lower pole(LP) renal stones with a diameter of 1.5-2.5 cm.METHODS A total of 216 ... AIM To compare the outcomes of retrograde intrarenal surgery(RIRS) and miniaturized percutaneous nephrolithotomy(mini-PCNL) in treating lower pole(LP) renal stones with a diameter of 1.5-2.5 cm.METHODS A total of 216 patients who underwent mini-PCNL(n = 103) or RIRS n = 113) for LP stones with a diameter of 1.5-2.5 cm were enrolled between December 2015 and April 2017 at the Urology Department of Ningbo Urology and Nephrology Hospital.RESULTS Significant differences were found in the hospital stay(9.39 ± 4.01 vs 14.08 ± 5.26, P < 0.0001) and hospitalization costs(2624.5 ± 513.36 vs 3255.2 ± 976.5, P < 0.0001) between the RIRS and mini-PCNL groups. The mean operation time was not significantly different between the RIRS group(56.48 ± 24.77) and the mini-PCNL group(60.04 ± 30.38, P = 0.345). The stone-free rates at the first postoperative day(RIRS vs mini-PCNL: 90.2% vs 93.2%, P = 0.822) and the second month postoperatively(RIRS vs mini-PCNL: 93.8% vs 95.1%, P = 0.986) were not significantly different.CONCLUSION RIRS and mini-PCNL are both safe and effective methods for treating LP stones with a diameter of 1.5-2.5 cm. RIRS can be considered as an alternative to PCNL for the treatment for LP stones of 1.5-2.5 cm. 展开更多
关键词 RETROGRADE intrarenal surgery PERCUTANEOUS nephrolithotripsy LOWER pole kidney stones MINIATURIZED PERCUTANEOUS NEPHROLITHOTOMY
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