Background Previous studies have shown that an echocardiographic right/left ventricular end-diastolic diameter ratio(RV/LV ratio)≥0.9 is an independent predictor of poor prognosis in patients with acute pulmonary emb...Background Previous studies have shown that an echocardiographic right/left ventricular end-diastolic diameter ratio(RV/LV ratio)≥0.9 is an independent predictor of poor prognosis in patients with acute pulmonary embolism. The prognostic value of the RV/LV ratio in patients with idiopathic pulmonary arterial hypertension(IPAH) is still unknown. Methods We retrospectively enrolled 95 consecutive patients with newly diagnosed IPAH and 16 of them were reevaluated by echocardiography at 3-12 months following targeted therapy.Follow-up data were obtained by telephone interviews and review of the patients’ records.Results The RV/LV ratio was in parallel with the severity of World Health Orgnization(WHO) functional class and mean right atrial pressure.The RV/LV ratio was positively correlated with total pulmonary resistance(P P P 2 saturation(P P = 0.001),weight and absence of targeted therapy were independent predictors of death.No significant changes in the RV/LV ratio before and after targeted therapy were observed. A baseline RV/LV ratio≥0.84 or a further increase in the RV/LV ratio during targeted therapy indicated a poor prognosis. Conclusions The RV/LV ratio helps to assess the severity of IPAH and serves as an independent predictor of prognosis in patients with IPAH.展开更多
Objective To investigate the relations between the pathological contraction of the valve and sub-valvular apparatus in rheumatic mitral stenosis and end-diastolic volume of left ventricle. Method From 1990-2004, 90 pa...Objective To investigate the relations between the pathological contraction of the valve and sub-valvular apparatus in rheumatic mitral stenosis and end-diastolic volume of left ventricle. Method From 1990-2004, 90 patients with only moderate or severe rheumatic mitral stenosis （mitral group）, and 24 patients with combined moderate or severe rheumatic mitral stenosis and significant aortic regurgitation （ combined valves group）, diagnostically confirmed by surgery and pathology, were measured using echocardiaogram the end-diastolic volume and diameter, stroke volume and ejection fraction of left ventricle. Result Compared with mitral group combined valves group showed slight increases of end-diastolic volume and diameter （116.49 ± 37.93 ml and 136.72±70.67 ml, respectively; 49.34 ± 6.71 mm and 51.08 ± 8.32 mm, respectively; both P 〈 0.05）, and slight decreases of ejection fraction, but significant increases of stroke volume （71.37 ± 25.01 ml and 91.06 ± 36.67 ml, respectively; P〈0.05） of left ventricle. Conclusion The pathological shortening of mitral valve and sub-valvular apparatus caused by long-term rheumatic disease is the main cause of decreased left ventricular volume in mitral stenosis.展开更多
The exact solution for the combined KS and KdV equation is obtained via introducing a simple and effective nonlinear transformations.This method is very concise and primary and can be applied to other unintegrable non...The exact solution for the combined KS and KdV equation is obtained via introducing a simple and effective nonlinear transformations.This method is very concise and primary and can be applied to other unintegrable nonlinear evolution equations.It is common knowledge that the Korteweg de Vries(KdV) equation [1] (1)has been proposed as model equation for the weakly nonlinear long waves which occur in many different physical systems; the Kuramoto-Sivashinsky (KS) equationis one of the simplest nonliaear partial differential equations that exhibit Chaotic behavior frequently encounted in the study of continous media [2-4] . Many interesting mathematical and physical properties of eqs. (1) and (2) have been studied widely. But, in several problems where a lonq wavelength oscilatory instability is found, the noulineai evolution of the perturbations near rriticality is governed by the dispersion modified Kuramoto-Sivashi nsky equation(3)ft is clear that this equation is a combination of the KdV and展开更多
BACKGROUND Coronary artery stenosis(CAS)is the most common type of heart disease and the leading cause of death in both men and women globally.CAS occurs when the arteries that supply blood to the heart muscle harden ...BACKGROUND Coronary artery stenosis(CAS)is the most common type of heart disease and the leading cause of death in both men and women globally.CAS occurs when the arteries that supply blood to the heart muscle harden and become narrower due to plaque buildup-cholesterol and other material-on their inner walls.As a result,the heart muscle cannot receive the blood or oxygen it needs.Most heart attacks happen when a blood clot suddenly cuts off the hearts'blood supply,causing permanent heart damage.AIM To analyze the relationship between the left ventricular ejection fraction(LVEF),left ventricular strain(LVS),and coronary stenosis.METHODS A total of 190 participants were enrolled in this trail.The control group comprised 93 healthy individuals,and observation group comprised 97 patients with coronary heart disease who were hospitalized between July 2020 and September 2021.Coronary lesions were assessed using the Gensini score,and the LVEF and LVS were measured using magnetic resonance imaging(MRI).The interaction between the LVEF and LVS was examined using a linear regression model.The relationship between LVEF and coronary stenosis was examined using Spearman’s correlation.RESULTS The LVEF of the observation group was lower than that of the control group.The left ventricular end-systolic volume(LVESV)and left ventricular end-diastolic volume(LVEDV)of the observation group were significantly higher than those of the control group(P<0.05).The longitudinal and circumferential strains(LS,CS)of the observation group were significantly higher than those of the control group;however,the radial strain(RS)of the observation group was significantly lower than that of the control group(P<0.05).LVS,LS,and CS were significantly negatively correlated with the LVEF,and RS was positively correlated with the LVEF.There were significant differences in the LVEF,LVESV,and LVEDV of patients with different Gensini scores;the LVEF significantly decreased and the LVESV and LVEDV increased with increasing Gensini scores(P<0.05).In the observation group,the LVEF was negatively correlated and the LVESV and LVEDV were positively correlated with coronary stenosis(P<0.05).CONCLUSION The LVEF measured using MRI is significantly linearly correlated with LVS and negatively correlated with coronary stenosis.展开更多
文摘Background Previous studies have shown that an echocardiographic right/left ventricular end-diastolic diameter ratio(RV/LV ratio)≥0.9 is an independent predictor of poor prognosis in patients with acute pulmonary embolism. The prognostic value of the RV/LV ratio in patients with idiopathic pulmonary arterial hypertension(IPAH) is still unknown. Methods We retrospectively enrolled 95 consecutive patients with newly diagnosed IPAH and 16 of them were reevaluated by echocardiography at 3-12 months following targeted therapy.Follow-up data were obtained by telephone interviews and review of the patients’ records.Results The RV/LV ratio was in parallel with the severity of World Health Orgnization(WHO) functional class and mean right atrial pressure.The RV/LV ratio was positively correlated with total pulmonary resistance(P P P 2 saturation(P P = 0.001),weight and absence of targeted therapy were independent predictors of death.No significant changes in the RV/LV ratio before and after targeted therapy were observed. A baseline RV/LV ratio≥0.84 or a further increase in the RV/LV ratio during targeted therapy indicated a poor prognosis. Conclusions The RV/LV ratio helps to assess the severity of IPAH and serves as an independent predictor of prognosis in patients with IPAH.
文摘Objective To investigate the relations between the pathological contraction of the valve and sub-valvular apparatus in rheumatic mitral stenosis and end-diastolic volume of left ventricle. Method From 1990-2004, 90 patients with only moderate or severe rheumatic mitral stenosis （mitral group）, and 24 patients with combined moderate or severe rheumatic mitral stenosis and significant aortic regurgitation （ combined valves group）, diagnostically confirmed by surgery and pathology, were measured using echocardiaogram the end-diastolic volume and diameter, stroke volume and ejection fraction of left ventricle. Result Compared with mitral group combined valves group showed slight increases of end-diastolic volume and diameter （116.49 ± 37.93 ml and 136.72±70.67 ml, respectively; 49.34 ± 6.71 mm and 51.08 ± 8.32 mm, respectively; both P 〈 0.05）, and slight decreases of ejection fraction, but significant increases of stroke volume （71.37 ± 25.01 ml and 91.06 ± 36.67 ml, respectively; P〈0.05） of left ventricle. Conclusion The pathological shortening of mitral valve and sub-valvular apparatus caused by long-term rheumatic disease is the main cause of decreased left ventricular volume in mitral stenosis.
文摘The exact solution for the combined KS and KdV equation is obtained via introducing a simple and effective nonlinear transformations.This method is very concise and primary and can be applied to other unintegrable nonlinear evolution equations.It is common knowledge that the Korteweg de Vries(KdV) equation [1] (1)has been proposed as model equation for the weakly nonlinear long waves which occur in many different physical systems; the Kuramoto-Sivashinsky (KS) equationis one of the simplest nonliaear partial differential equations that exhibit Chaotic behavior frequently encounted in the study of continous media [2-4] . Many interesting mathematical and physical properties of eqs. (1) and (2) have been studied widely. But, in several problems where a lonq wavelength oscilatory instability is found, the noulineai evolution of the perturbations near rriticality is governed by the dispersion modified Kuramoto-Sivashi nsky equation(3)ft is clear that this equation is a combination of the KdV and
文摘BACKGROUND Coronary artery stenosis(CAS)is the most common type of heart disease and the leading cause of death in both men and women globally.CAS occurs when the arteries that supply blood to the heart muscle harden and become narrower due to plaque buildup-cholesterol and other material-on their inner walls.As a result,the heart muscle cannot receive the blood or oxygen it needs.Most heart attacks happen when a blood clot suddenly cuts off the hearts'blood supply,causing permanent heart damage.AIM To analyze the relationship between the left ventricular ejection fraction(LVEF),left ventricular strain(LVS),and coronary stenosis.METHODS A total of 190 participants were enrolled in this trail.The control group comprised 93 healthy individuals,and observation group comprised 97 patients with coronary heart disease who were hospitalized between July 2020 and September 2021.Coronary lesions were assessed using the Gensini score,and the LVEF and LVS were measured using magnetic resonance imaging(MRI).The interaction between the LVEF and LVS was examined using a linear regression model.The relationship between LVEF and coronary stenosis was examined using Spearman’s correlation.RESULTS The LVEF of the observation group was lower than that of the control group.The left ventricular end-systolic volume(LVESV)and left ventricular end-diastolic volume(LVEDV)of the observation group were significantly higher than those of the control group(P<0.05).The longitudinal and circumferential strains(LS,CS)of the observation group were significantly higher than those of the control group;however,the radial strain(RS)of the observation group was significantly lower than that of the control group(P<0.05).LVS,LS,and CS were significantly negatively correlated with the LVEF,and RS was positively correlated with the LVEF.There were significant differences in the LVEF,LVESV,and LVEDV of patients with different Gensini scores;the LVEF significantly decreased and the LVESV and LVEDV increased with increasing Gensini scores(P<0.05).In the observation group,the LVEF was negatively correlated and the LVESV and LVEDV were positively correlated with coronary stenosis(P<0.05).CONCLUSION The LVEF measured using MRI is significantly linearly correlated with LVS and negatively correlated with coronary stenosis.
