In 1945,Porter et al.published an electon microscopy study of cultured chick fibroblasts in which they observed:'a granular background and details of a darker lacelike reticulum which in places appears to be made up...In 1945,Porter et al.published an electon microscopy study of cultured chick fibroblasts in which they observed:'a granular background and details of a darker lacelike reticulum which in places appears to be made up of chains of"vesicles"'(Porter et al.,1945).This constituted the first published observation of the endoplasmic reticulum(ER)and,while it was not evident at that time,this cytoplasmic system of interconnecting membrane-lined channels, comprising vesicles, tubules and cisternae, has numerous important functions.展开更多
文摘In 1945,Porter et al.published an electon microscopy study of cultured chick fibroblasts in which they observed:'a granular background and details of a darker lacelike reticulum which in places appears to be made up of chains of"vesicles"'(Porter et al.,1945).This constituted the first published observation of the endoplasmic reticulum(ER)and,while it was not evident at that time,this cytoplasmic system of interconnecting membrane-lined channels, comprising vesicles, tubules and cisternae, has numerous important functions.