Risk factors for predicting early variceal rebleeding after endoscopic variceal ligation

AIM: To analyze the clinical risk factors for early variceal rebleeding after endoscopic variceal ligation (EVL).METHODS: 342 cirrhotic patients with esophageal varices who received elective EVL to prevent bleeding or rebleeding at our endoscopy center between January 2005 and July 2010.were included in this study.The early rebleeding cases after EVL were confirmed by clinical signs or endoscopy.A case-control study was performed comparing the patients presenting with early rebleeding with those without this complication.RESULTS: The incidence of early rebleeding after EVL was 7.60%,and the morbidity of rebleeding was 26.9%.Stepwise multivariate logistic regression analysis showed that four variables were independent risk factors for early rebleeding: moderate to excessive ascites [odds ratio (OR) 62.83,95% CI: 9.39-420.56,P < 0.001],the number of bands placed (OR 17.36,95% CI: 4.00-75.34,P < 0.001),the extent of varices (OR 15.41,95% CI: 2.84-83.52,P = 0.002) and prothrombin time (PT) > 18 s (OR 11.35,95% CI: 1.93-66.70,P = 0.007).CONCLUSION: The early rebleeding rate after EVL is mainly affected by the volume of ascites,number of rubber bands used to ligate,severity of varices and prolonged PT.Effective measures for prevention and treatment should be adopted before and after EVL.

经胃镜使用套扎器单环套扎治疗食管黏膜下肿瘤57例

目的:探讨经胃镜使用套扎器单环套扎食管黏膜下肿瘤的治疗价值.方法:对57例经超声胃镜微探头诊断为食管黏膜下肿瘤的患者进行有弹性的单环套扎治疗.结果:57例患者的食管黏膜下肿瘤均完全切除,未发生任何并发症(穿孔、出血).1例1 mo复查时病变无改变,给与重新套扎.经过1 mo、3 mo及6 mo的胃镜随访,所有病例无复发,无不良反应.结论:经胃镜对食管黏膜下肿瘤进行有弹性的单环套扎术是有效和安全的治疗方法.

内镜下套扎术联合药物治疗食管静脉曲张出血的效果

目的探讨食管静脉曲张出血行内镜下套扎术联合药物治疗的效果。方法选择2011年10月-2013年10月在浙江省湖州市中心医院诊治的食管静脉曲张出血患者124例，按照随机数字表法分成两组，每组各62例，对照组予以内镜下套扎术联合常规止血抗炎药物治疗，研究组予以内镜下套扎术与泮托拉唑、生长抑素、普萘洛尔等联合药物治疗，分析不同分级的再出血、两组止血效果、并发症情况。结果不同Child—Pugh分级再出血率比较，Child—PughC级明显高于Child—PughA及B组，差异有统计学意义（P〈0．05）。且研究组出血再发率为3．23％．复发率为6．45％，比对照组（19．35％、24．19％）降低，差异有统计学意义（P〈0．05）。同时研究组伴发食管溃疡、门脉高压胃病发生率为3．23％、3．23％，比对照组（19．35％、20．97％）降低，差异有统计学意义（P〈0．05）。结论针对食管静脉曲张出血患者，予内镜下套扎术与联合药物治疗，患者的止血效果良好，且并发症较少，具有一定临床应用和研究价值。

内镜下食管静脉曲张套扎术的护理

目的 :总结内镜下食管静脉曲张套扎术护理配合的经验。方法 :术前建立静脉通道 ,备齐有关药物及急救器械 ;术中监测患者的生命体征 ;术后患者卧床休息 ,密切观察病情变化 ,有无早期再出血。结果 :本组 4 5例共结扎312点 ,12例套扎 1次 ,11例套扎 2次 ,2 2例套扎 3次 ,急症止血 15例 ,达10 0 % ;术后 2周复查 ,静脉闭塞 2 9例 ,达 6 4 %。结论 :内镜下食管静脉曲张套扎术 ,由于术前、术中、术后护理的密切配合 ,提高了静脉曲张套扎术的安全性和成功率。

单环套扎器治疗上消化道黏膜下肿瘤的疗效分析

目的评估单环套扎器治疗上消化道黏膜下肿瘤的安全性及实用性。方法经电子超声胃镜诊断为上消化道黏膜下肿瘤患者59例,其中来源于黏膜肌层24例,黏膜下层9例,固有肌层26例,均应用单环套扎器进行套扎治疗,随访观察疗效和安全性。结果食管病变于套扎后均未出现出血、穿孔等严重并发症,3例胃底固有肌层病变因穿孔转外科手术治疗。结论对于直径<1.2 cm的食管黏膜下肿瘤,套扎器治疗安全有效,胃底位于固有肌层的黏膜下肿瘤仍有一定的穿孔几率。