BACKGROUND Ductal carcinoma in situ(DCIS)arising within fibroadenoma is a type of tumor that is rarely encountered in clinic,with only about 100 cases of carcinoma arising within a fibroadenoma reported in the literat...BACKGROUND Ductal carcinoma in situ(DCIS)arising within fibroadenoma is a type of tumor that is rarely encountered in clinic,with only about 100 cases of carcinoma arising within a fibroadenoma reported in the literature.Here,we present two cases of breast DCIS arising within a fibroadenoma and discuss their clinical and imaging findings as well as treatment.CASE SUMMARY The patients did not have cancer-related personal and family histories.Case 1(a 49-year-old woman)was diagnosed with a bilateral breast nodule in May 2018 and was followed(preoperative imaging data including ultrasound and mammography)for 3 years;she underwent an excisional biopsy to address an enlargement in nodule size.Case 2(a 37-year-old woman)was diagnosed with a left breast nodule in June 2021 and consequently received vacuum-assisted biopsy of the tumor which appeared as“irregularly shaped”and“unevenly textured”tissue on ultrasound.The pathological diagnosis was clear in both cases.Both patients underwent breast-conserving surgery and sentinel lymph node biopsy.The two cases received or planned to receive radiotherapy as well as endocrine therapy(tamoxifen).CONCLUSION Breast DCIS arising within a fibroadenoma is rare,but patients treated with radiotherapy and endocrine therapy can have good prognosis.展开更多
Osteoid osteoma is a benign bone tumor that is commonly seen in males in their second and third decade of life. The tumor commonly occurs in long bones (proximal femur and tibia) and rarely in the spine, hands and fee...Osteoid osteoma is a benign bone tumor that is commonly seen in males in their second and third decade of life. The tumor commonly occurs in long bones (proximal femur and tibia) and rarely in the spine, hands and feet. It presents with bone pain worsening at night and responds well to nonsteroidal anti-inflammatory drugs. It is usually treated conservatively but sometimes with surgery if medical treatment fails. We present a case of 19-year-old girl, who presented with mild pain over lateral aspect of right ankle for 6 months duration. The pain was provoked by sporting activities, and was initially relieved by analgesics, until recently, hence her presentation. CT scan was done and showed a well-defined central nodule of bone. She had an open excisional biopsy, and the histology showed a diagnosis of osteoid osteoma. Post-operative healing was uneventful, the fracture united after 6 weeks and she was able to ambulate without any pain 3 months post-surgery.展开更多
Schwannomas are benign, well-encapsulated and slow growing tumor arising from Schwann cells of the peripheral nerve sheath. They commonly saw in the head and neck, rarely from deep peroneal nerve in the lower limb. We...Schwannomas are benign, well-encapsulated and slow growing tumor arising from Schwann cells of the peripheral nerve sheath. They commonly saw in the head and neck, rarely from deep peroneal nerve in the lower limb. We present a case of 42-year-old active national hockey coach, who presented with mild pain and numbness over lateral aspect of left leg for 2 years. The pain was provoked by sporting activities, and was initially relieved by analgesics, until recently, hence his presentation. MRI was done and showed well-defined oval lesion within the deep intermuscular fascia between tibialis anterior and extensor halluces longus muscles. He had an open dissection, and the histology showed a diagnosis of schwannoma. Post-operative healing was uneventful, the pain and numbness improving after 12 months.展开更多
文摘BACKGROUND Ductal carcinoma in situ(DCIS)arising within fibroadenoma is a type of tumor that is rarely encountered in clinic,with only about 100 cases of carcinoma arising within a fibroadenoma reported in the literature.Here,we present two cases of breast DCIS arising within a fibroadenoma and discuss their clinical and imaging findings as well as treatment.CASE SUMMARY The patients did not have cancer-related personal and family histories.Case 1(a 49-year-old woman)was diagnosed with a bilateral breast nodule in May 2018 and was followed(preoperative imaging data including ultrasound and mammography)for 3 years;she underwent an excisional biopsy to address an enlargement in nodule size.Case 2(a 37-year-old woman)was diagnosed with a left breast nodule in June 2021 and consequently received vacuum-assisted biopsy of the tumor which appeared as“irregularly shaped”and“unevenly textured”tissue on ultrasound.The pathological diagnosis was clear in both cases.Both patients underwent breast-conserving surgery and sentinel lymph node biopsy.The two cases received or planned to receive radiotherapy as well as endocrine therapy(tamoxifen).CONCLUSION Breast DCIS arising within a fibroadenoma is rare,but patients treated with radiotherapy and endocrine therapy can have good prognosis.
文摘Osteoid osteoma is a benign bone tumor that is commonly seen in males in their second and third decade of life. The tumor commonly occurs in long bones (proximal femur and tibia) and rarely in the spine, hands and feet. It presents with bone pain worsening at night and responds well to nonsteroidal anti-inflammatory drugs. It is usually treated conservatively but sometimes with surgery if medical treatment fails. We present a case of 19-year-old girl, who presented with mild pain over lateral aspect of right ankle for 6 months duration. The pain was provoked by sporting activities, and was initially relieved by analgesics, until recently, hence her presentation. CT scan was done and showed a well-defined central nodule of bone. She had an open excisional biopsy, and the histology showed a diagnosis of osteoid osteoma. Post-operative healing was uneventful, the fracture united after 6 weeks and she was able to ambulate without any pain 3 months post-surgery.
文摘Schwannomas are benign, well-encapsulated and slow growing tumor arising from Schwann cells of the peripheral nerve sheath. They commonly saw in the head and neck, rarely from deep peroneal nerve in the lower limb. We present a case of 42-year-old active national hockey coach, who presented with mild pain and numbness over lateral aspect of left leg for 2 years. The pain was provoked by sporting activities, and was initially relieved by analgesics, until recently, hence his presentation. MRI was done and showed well-defined oval lesion within the deep intermuscular fascia between tibialis anterior and extensor halluces longus muscles. He had an open dissection, and the histology showed a diagnosis of schwannoma. Post-operative healing was uneventful, the pain and numbness improving after 12 months.
