A highly selective nitric oxide（NO） sensor is fabricated and applied to devise an enhanced flow injection analysis（FIA） system for S-nitrosothiols（RSNOs） measurement in biological samples.The NO sensor is prepar...A highly selective nitric oxide（NO） sensor is fabricated and applied to devise an enhanced flow injection analysis（FIA） system for S-nitrosothiols（RSNOs） measurement in biological samples.The NO sensor is prepared using a polytetrafluoroethylene（PTFE） gas-permeable membrane loaded with Teflon AF？ solution,a copolymer of tetrafluoroethylene and 2,2-bis（trifluoroethylene）-4,5-difluoro -l,3-dioxole,to improve selectivity.This method is much simpler and possesses good performance over a wide range of RSNOs concentrations.Standard deviation for three parallel measurements of blood plasma is 4.0%.The use of the gas sensing configuration as the detector enhances selectivity of the FIA measurement vs.using less selective electrochemical detectors that do not use PTFE/Teflon type outer membranes.展开更多
基金the Project of Base for Introducing Talents of Discipline to Universities(111 project,NoB07012)National Scholarship Fund of the China Scholarship Council for supporting visiting students in foreign universities
文摘A highly selective nitric oxide（NO） sensor is fabricated and applied to devise an enhanced flow injection analysis（FIA） system for S-nitrosothiols（RSNOs） measurement in biological samples.The NO sensor is prepared using a polytetrafluoroethylene（PTFE） gas-permeable membrane loaded with Teflon AF？ solution,a copolymer of tetrafluoroethylene and 2,2-bis（trifluoroethylene）-4,5-difluoro -l,3-dioxole,to improve selectivity.This method is much simpler and possesses good performance over a wide range of RSNOs concentrations.Standard deviation for three parallel measurements of blood plasma is 4.0%.The use of the gas sensing configuration as the detector enhances selectivity of the FIA measurement vs.using less selective electrochemical detectors that do not use PTFE/Teflon type outer membranes.
