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基于FP-growth的老年行人交通事故损伤致因研究
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作者 刘永涛 张慧臣 +3 位作者 袁诗泉 高隆鑫 王鹏 赵晨 《中国安全生产科学技术》 CAS CSCD 北大核心 2024年第6期176-182,共7页
为研究老年行人交通事故相关因素及其对损伤程度的影响,以中国交通事故深度调查数据库中2013—2023年710起机动车-老年行人事故为分析对象,利用FP-growth算法挖掘出4类影响因素28个类型变量共5594项关联规则。研究结果表明:行人年龄、... 为研究老年行人交通事故相关因素及其对损伤程度的影响,以中国交通事故深度调查数据库中2013—2023年710起机动车-老年行人事故为分析对象,利用FP-growth算法挖掘出4类影响因素28个类型变量共5594项关联规则。研究结果表明:行人年龄、碰撞速度、事故时间段及事故地点是影响老年行人事故死亡率的显著因素。特别是,行人年龄和碰撞速度对死亡率有显著影响,随着碰撞速度的增加,死亡率显著上升;60岁及以上老年行人年龄每增加1岁,其死亡率提升0.037倍。此外,事故发生在夜间、郊区或村庄的死亡率更高。研究结果可为提高老年行人交通安全,制定相关安全措施提供一定参考。 展开更多
关键词 fp-growth算法 逻辑回归模型 老年行人安全 交通事故数据分析
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基于FP-growth算法的交通事故数据关联规则挖掘研究
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作者 马健 谢雨晴 +2 位作者 张丽岩 王燕 周欢生 《科技创新与生产力》 2024年第9期95-97,共3页
为了探寻多种事故影响因素共同作用下诱发交通事故的某种规律以及各因素间的关系,本文采用FP-growth算法对收集到的交通事故数据进行分析研究,挖掘其中的潜在价值信息,找出事故发生的原因,根据分析结果给相关部门提出建议,帮助城市交通... 为了探寻多种事故影响因素共同作用下诱发交通事故的某种规律以及各因素间的关系,本文采用FP-growth算法对收集到的交通事故数据进行分析研究,挖掘其中的潜在价值信息,找出事故发生的原因,根据分析结果给相关部门提出建议,帮助城市交通管理者制定更有效的管理措施,以达到降低交通事故发生频率的目的。 展开更多
关键词 交通事故 关联规则 fp-growth
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基于改进FP-Growth算法和贝叶斯的营业线施工安全风险分析
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作者 蔡近近 宋瑞 +2 位作者 何世伟 赵日鑫 姜俊平 《铁道科学与工程学报》 EI CAS CSCD 北大核心 2024年第8期3370-3381,共12页
铁路营业线施工事故致因因素众多且存在关联关系,挖掘事故致因之间的关联关系和因果关系对事故的预防管控具有重要意义。通过文本挖掘对2010—2022年某路局营业线事故调查报告进行处理,提取出51个事故致因因素。基于事故因果连锁理论将... 铁路营业线施工事故致因因素众多且存在关联关系,挖掘事故致因之间的关联关系和因果关系对事故的预防管控具有重要意义。通过文本挖掘对2010—2022年某路局营业线事故调查报告进行处理,提取出51个事故致因因素。基于事故因果连锁理论将致因因素分为人因层、设备层、环境层、管理层4个层级进行分层分析,构建铁路营业线施工事故致因体系。基于压缩算法和差分编码对传统FP-Growth算法进行改进,以此对铁路营业线施工事故致因进行挖掘,找到满足提升度要求的高支持度关联规则和高置信度关联规则,发现关键致因关联和事故致因规律。基于贝叶斯网络理论、致因关联关系和专家经验建立营业线施工安全风险贝叶斯网络,结合复杂网络理论分析网络节点度、聚类系数与节点介数等特征,找到关键致因因素。在此基础上,运用因果推理和故障诊断推理进一步剖析营业线施工过程中的高风险致因,并从“人防、物防、技防”3方面提出预防管控措施。案例结果表明:施工人员操作不当、施工造成接触网故障、施工导致设施设备侵限、施工作业损害电缆设备、施工造成轨道电路故障和施工、检修、清扫设备耽误列车类事故之间的关联关系较为频繁,且为红光带事故的高概率致因,在施工作业过程中应多层次重点预防管控。研究成果为铁路营业线施工安全管理提供一种新的风险分析方法。 展开更多
关键词 铁路营业线施工事故 改进fp-growth算法 关联规则挖掘 贝叶斯网络推理 致因体系
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基于FP-Growth算法的直流输电系统阀基电子设备缺陷关联性分析
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作者 肖耀辉 余俊松 +3 位作者 李为明 薛海平 王永平 戴剑丰 《电子器件》 CAS 2024年第4期1053-1059,共7页
换流阀控制设备作为直流输电系统的核心设备,对其阀基电子设备进行缺陷异常分析是保证直流输电系统稳定可靠运行的基础。提出一种基于FP-Growth算法的直流输电阀基电子设备缺陷关联性分析方法。首先基于阀基电子设备的基本结构与原理,... 换流阀控制设备作为直流输电系统的核心设备,对其阀基电子设备进行缺陷异常分析是保证直流输电系统稳定可靠运行的基础。提出一种基于FP-Growth算法的直流输电阀基电子设备缺陷关联性分析方法。首先基于阀基电子设备的基本结构与原理,采集阀基电子设备缺陷数据;接着对原始数据进行预处理,量化编码后导入FP-Growth算法,通过构建FP-Tree,计算其支持度和置信度,分析阀基电子设备的缺陷特征和影响因素以及各元件之间的关联关系。该方法能高效智能实现对直流输电系统核心设备缺陷的关联分析及故障溯源,为运维人员检修策略的制定提供了理论依据。最后以实际直流输电系统换流阀阀基电子设备缺陷数据仿真算例对所提方法的有效性进行了验证。 展开更多
关键词 直流输电系统 阀基电子设备 fp-growth算法 缺陷关联性分析
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基于FP-Growth算法的运毒嫌疑车辆智能推荐研究
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作者 陈柏翰 罗安飞 《贵州警察学院学报》 2024年第3期84-91,共8页
毒品运输是毒品犯罪的重要环节,虽然毒品运输的手段越来越多样化,但公路运输仍然是主要的运输方式之一,而运毒人员有着各自经典的运毒模式。文中对运毒模式进行特征挖掘,发现存在前后车伴随的规律,根据实际业务中前后车行为以半小时为... 毒品运输是毒品犯罪的重要环节,虽然毒品运输的手段越来越多样化,但公路运输仍然是主要的运输方式之一,而运毒人员有着各自经典的运毒模式。文中对运毒模式进行特征挖掘,发现存在前后车伴随的规律,根据实际业务中前后车行为以半小时为时间间隔导向,建模时选择PostgreSQL数据库。在数据库中建立过往车辆前半小时中间表、后半小时中间表、中间跨度表,运用人工智能数据挖掘技术实现从大量的通行车辆中抽取车辆伴随信息,采用FP-Growth算法挖掘频繁项集,查找高频出现车牌号,通过设定阈值并找到对应的关联规则,经过缉毒民警提供的黑名单进行过滤并排序,最后进行车辆嫌疑度的推荐,为民警拦截嫌疑车辆提供支持,能够在一定程度上提高对嫌疑车辆排查的针对性、准确性和有效性。 展开更多
关键词 毒品运输 运毒模式 特征挖掘 fp-growth算法 关联规则
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基于FP-growth算法的高维混合属性数据挖掘方法
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作者 梁树杰 《计算技术与自动化》 2024年第2期88-92,共5页
常规高维混合属性数据挖掘方法多采用云平台技术,无法完整保留数据的结构相似性,使得数据挖掘效率较低。为此,提出了基于FP-growth算法的高维混合属性数据挖掘方法。为了改善数据质量,根据高维混合属性数据在数据库中的存储结构,采用了... 常规高维混合属性数据挖掘方法多采用云平台技术,无法完整保留数据的结构相似性,使得数据挖掘效率较低。为此,提出了基于FP-growth算法的高维混合属性数据挖掘方法。为了改善数据质量,根据高维混合属性数据在数据库中的存储结构,采用了一种固定算法实现数据去噪,并依据数据类型计算分类型和数值型相似度,结合FP-growth算法对频繁项样本分支进行筛选生成项表头,保证数据结构相似性的完整性,通过搜索项表头输出有效关联规则,实现数据挖掘过程。实验结果表明,所提方法具有较高的挖掘效率。 展开更多
关键词 数据挖掘 fp-growth算法 固定算法 高维混合属性
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基于疗效加权FP-Growth算法的干燥综合征组方用药挖掘分析 被引量:4
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作者 丁弋美 侯佳奇 薛鸾 《世界科学技术-中医药现代化》 CSCD 北大核心 2023年第1期324-330,共7页
目的以数据挖掘方法探索干燥综合征组方用药规律,并探讨加权FP-Growth算法在中药方剂挖掘中的应用,为中医临床用药分析提供新思路。方法以中医临床疗效作为加权标准,以集对分析为基础计算疗效基数ρ,以w=(ρ_(对照组)-ρ_(实验组))/ρ_... 目的以数据挖掘方法探索干燥综合征组方用药规律,并探讨加权FP-Growth算法在中药方剂挖掘中的应用,为中医临床用药分析提供新思路。方法以中医临床疗效作为加权标准,以集对分析为基础计算疗效基数ρ,以w=(ρ_(对照组)-ρ_(实验组))/ρ_(对照组)+δ计算最终加权值,以加权FP-Growth算法为关联规则分析方法进行数据挖掘,分别计算支持度及提升度,对挖掘结果进行支持度和提升度的分析,综合得出分析结果。结果最常用中药前5位为:麦冬、生地黄、甘草、白芍、北沙参。综合支持度及提升度分析挖掘结果后提出以麦冬、生地黄、北沙参、甘草为基本底方,丹参、玄参、黄芪为祛瘀,解毒,补气加减方向的代表。并挖掘出了两个值得关注的高支持度药团:补脾肾的茯苓-山茱萸-山药-丹皮药团及补气血的白芍-太子参-五味子-当归药团。结论干燥综合征临床用药以养阴生津药为主,配伍具有经典方特色。加权FP-Growth算法用于组方用药分析可提炼核心组方思路及加减方向,有助于中医药经验的继承与发展。 展开更多
关键词 干燥综合征 用药分析 关联规则 fp-growth算法 集对分析
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数据点位置并行FP-Growth挖掘算法仿真 被引量:4
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作者 乔阳阳 王丽娟 《计算机仿真》 北大核心 2023年第5期501-505,共5页
当数据集发生非法入侵时,原数据属性会遭到破坏,且由于数据本身的不确定性及噪声等问题,入侵数据点位置的挖掘难度较大。为此,提出基于并行频繁模式增长算法(Frequent Pattern Growth, FP-Growth)的数据点位置智能挖掘方法。建立信息熵... 当数据集发生非法入侵时,原数据属性会遭到破坏,且由于数据本身的不确定性及噪声等问题,入侵数据点位置的挖掘难度较大。为此,提出基于并行频繁模式增长算法(Frequent Pattern Growth, FP-Growth)的数据点位置智能挖掘方法。建立信息熵-主成分分析法融合算法(Entropy-Principle Compoent Analysis, E-PCA),对大数据降维。融合入侵检测和K均值聚类算法(Intrusion Detection Systems K-means clustering algorithm, IDS K-means算法)和并行FP-Growth算法,实现入侵数据的检测。利用邻居节点数据投票的方式实现入侵数据点位置智能挖掘。实验表明,所提方法检测入侵数据时误报率低于1.0%,数据点位置挖掘准确率高于98%,且能够精准实现正常数据与异常数据的聚类。以上结果均证明了所提方法具有更优的应用性能。 展开更多
关键词 并行算法 数据点位置挖掘 入侵数据检测
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基于FP-Growth算法的煤矿安全信息管理系统设计及应用 被引量:3
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作者 郭爱伟 杨真 +1 位作者 杜科科 张新祯 《中国矿业》 2023年第3期67-73,共7页
为将煤矿安全生产管理关口再度前移,强化对煤矿生产一线的安全管理,提出了基于FP-Growth算法的煤矿安全信息管理系统。首先明确了系统设计目标及架构设计方案,以移动智能手持终端等为前端设备,采用B/S模式结合JAVA、CSS等语言研发出可... 为将煤矿安全生产管理关口再度前移,强化对煤矿生产一线的安全管理,提出了基于FP-Growth算法的煤矿安全信息管理系统。首先明确了系统设计目标及架构设计方案,以移动智能手持终端等为前端设备,采用B/S模式结合JAVA、CSS等语言研发出可运行于内部局域网(Intranet)和互联网(Internet)并支持多终端互动的安全信息管理系统;其次研发了系统主要功能模块包括事故隐患排查、风险分级管控、不安全行为治理及其他功能等;最后将系统应用于陕北某矿,并基于FP-Growth算法对该矿事故隐患数据进行深度挖掘,分析其不同维度数据间的关联性。研究及应用结果表明:该系统的应用能够对煤矿事故隐患起到预防预警的作用,可有效遏制生产一线安全生产风险与事故隐患的发生,有效保障煤矿的安全、高效生产,为煤矿安全生产提供辅助决策。 展开更多
关键词 fp-growth算法 安全信息管理系统 事故隐患 风险分级管控 不安全行为
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基于FP-growth算法的多尺度用电异常行为检测方法 被引量:1
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作者 武亚光 张才俊 程飞飞 《电子设计工程》 2023年第23期118-121,126,共5页
异常用电行为检测直接关系到电力公司的利益。针对上述问题,提出一种基于FP-growth算法的多尺度用电异常行为检测方法。通过采集器远程获取用电数据,并对缺失数据填补和数据进行标准化处理。通过计算特征的重要性指数和贡献率选取多尺... 异常用电行为检测直接关系到电力公司的利益。针对上述问题,提出一种基于FP-growth算法的多尺度用电异常行为检测方法。通过采集器远程获取用电数据,并对缺失数据填补和数据进行标准化处理。通过计算特征的重要性指数和贡献率选取多尺度用电行为特征。利用FP-growth算法建立特征与用电行为之间的关联规则,根据支持度和置信度判断是否存在异常,实现用电异常行为检测。实验结果表明,所研究方法的F1值始终高于0.8,说明该方法的检测更为准确。 展开更多
关键词 fp-growth算法 多尺度特征 用电异常行为 检测方法
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Gorenstein强FP-内射模
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作者 方慧江 杨刚 《吉林大学学报(理学版)》 CAS 北大核心 2024年第5期1079-1084,共6页
首先,借助内射模的零调复形和Hom函子的理论,引入Gorenstein强FP-内射模的概念.其次,利用马蹄引理和构造拉回图的方法,研究Gorenstein强FP-内射模的同调性质,证明Gorenstein强FP-内射模类GS FI是内射可解类,关于直积及直和项封闭,并且... 首先,借助内射模的零调复形和Hom函子的理论,引入Gorenstein强FP-内射模的概念.其次,利用马蹄引理和构造拉回图的方法,研究Gorenstein强FP-内射模的同调性质,证明Gorenstein强FP-内射模类GS FI是内射可解类,关于直积及直和项封闭,并且如果任意R-模的Gorenstein强FP-内射维数有限,则(⊥GS FI,GS FI)构成完全遗传的余挠对. 展开更多
关键词 fp-内射模 Gorenstein强fp-内射模 余挠对
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Effects of thinning on the understory light environment of different stands and the photosynthetic performance and growth of the reforestation species Phoebe bournei 被引量:2
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作者 Shicheng Su Nianqing Jin Xiaoli Wei 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期12-28,共17页
Light levels determine regeneration in stands and a key concern is how to regulate the light environment of different stand types to the requirements of the understory.In this study,we selected three stands typical in... Light levels determine regeneration in stands and a key concern is how to regulate the light environment of different stand types to the requirements of the understory.In this study,we selected three stands typical in south China(a Cryptomeria japonica plantation,a Quercus acutissima plantation,and a mixed stand of both)and three thinning intensities to determine the best understory light environ-ment for 3-year-old Phoebe bournei seedlings.The canopy structure,understory light environment,and photosynthe-sis and growth indicators were assessed following thin-ning.Thinning improved canopy structure and understory light availability of each stand;species composition was the reason for differences in the understory light environ-ment.Under the same thinning intensity,the mixed stand had the greatest light radiation and most balanced spectral composition.P.bournei photosynthesis and growth were closely related to the light environment;all three stands required heavy thinning to create an effective and sustained understory light environment.In a suitable understory light environment,the efficiency of light interception,absorption,and use by seedlings was enhanced,resulting in a higher carbon assimilation the main limiting factor was stomatal conductance.As a shade-avoidance signal,red/far-red radia-tion is a critical factor driving changes in photosynthesis and growth of P.bournei seedlings,and a reduction increased light absorption and use capacity and height:diameter ratios.The growth advantage transformed from diameter to height,enabling seedlings to access more light.Our findings suggest that the regeneration of shade-tolerant species such as P.bournei could be enhanced if a targeted approach to thinning based on stand type was adopted. 展开更多
关键词 THINNING Understory light environment Phoebe bournei Photosynthetic performance growth performance
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GbLMI1 over-expression improves cotton aboveground vegetative growth 被引量:1
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作者 Zhili Chong Yunxiao Wei +7 位作者 Kaili Li Muhammad Aneeq Ur Rahman Chengzhen Liang Zhigang Meng Yuan Wang Sandui Guo Liangrong He Rui Zhang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第10期3457-3467,共11页
Leaves are the main organ for photosynthesis and organic synthesis in cotton.Leaf shape has important effects on photosynthetic efficiency and canopy formation,thereby affecting cotton yield.Previous studies have show... Leaves are the main organ for photosynthesis and organic synthesis in cotton.Leaf shape has important effects on photosynthetic efficiency and canopy formation,thereby affecting cotton yield.Previous studies have shown that LMI1(LATE MERISTEM IDENTITY1)is the main gene regulating leaf shape.In this study,the LMI1 gene was inserted into the 35S promoter expression vector,and cotton plants overexpressing LMI1(OE)were obtained through genetic transformation.Statistical analysis of the biological traits of the T_(1) and T_(2) populations showed that compared to the wild type(WT),OE plants had significantly larger leaves,thicker stems and significantly greater dry weight.Furthermore,plant sections of the main vein and petiole showed that the numbers of cells in those tissues of OE plants were significantly greater.In addition,RNA-seq analysis revealed the differential expression of genes related to gibberellin synthesis and NAC gene family(genes containing the NAC domain)between the OE and WT plants,suggesting that LMI1 is involved in secondary wall formation and cell proliferation,which promotes stem thickening.Moreover,Gene Ontology(GO)analysis revealed enrichment in the terms of calcium ion binding,and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis showed enrichment in the terms of fatty acid degradation,phosphatidylinositol signal transduction system,and c AMP(cyclic adenosine monophosphate)signal pathway.These results suggested that LMI1 OE plants are responsive to gibberellin hormone signals,and have altered messenger signals(c AMP,Ca^(2+))which amplify this function,to promote stronger aboveground vegetative growth.This study found the LMI1 greatly increased the vegetative growth in cotton,which is the basic requirement for higher yield. 展开更多
关键词 LMI1 over-expressing COTTON vegetative growth
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一种基于FP-Growth数据挖掘算法和正则表达式进行车驾管系统智能监管的实现方式
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作者 张硕 《道路交通科学技术》 2023年第4期37-43,共7页
本文基于公安交通管理综合应用平台车驾管业务登记事项内容和基于传统表结构的车驾管数据库后台,通过FP-Growth数据挖掘算法和正则表达式,对前台窗口输入数据和数据库已有数据进行自动模式匹配,自动过滤错误数据或进行数据业务信息预警... 本文基于公安交通管理综合应用平台车驾管业务登记事项内容和基于传统表结构的车驾管数据库后台,通过FP-Growth数据挖掘算法和正则表达式,对前台窗口输入数据和数据库已有数据进行自动模式匹配,自动过滤错误数据或进行数据业务信息预警,实现对车驾管业务进行事中和事后监督,从而提高数据质量,完成业务监管。本文先介绍FP-Growth的概念及运行机制,自动挖掘数据中的规律的方法,再介绍正则表达式对系统前端数据的初步过滤方法,最后给出整套的数据监管流程。本文主要在理论层面讲述监管的运行原理和小规模实验结论,因实验环境设备所限,不涉及大量数据库真实数据的操作。最后对该算法的优化方向进行了讨论。 展开更多
关键词 fp-growth 正则表达式 业务监督 运行原理 小规模实验结论
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Effects of maternal methyl donor intake during pregnancy on ileum methylation and function in an intrauterine growth restriction pig model 被引量:1
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作者 Yan Lin Jiangnan Wu +8 位作者 Yong Zhuo Bin Feng Zhengfeng Fang Shengyu Xu Jian Li Hua Zhao De Wu Lun Hua Lianqiang Che 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第3期1173-1189,共17页
Background Intrauterine growth retardation(IUGR)affects intestinal growth,morphology,and function,which leads to poor growth performance and high mortality.The present study explored whether maternal dietary methyl do... Background Intrauterine growth retardation(IUGR)affects intestinal growth,morphology,and function,which leads to poor growth performance and high mortality.The present study explored whether maternal dietary methyl donor(MET)supplementation alleviates IUGR and enhances offspring’s growth performance by improving intestinal growth,function,and DNA methylation of the ileum in a porcine IUGR model.Methods Forty multiparous sows were allocated to the control or MET diet groups from mating until delivery.After farrowing,8 pairs of IUGR and normal birth weight piglets from 8 litters were selected for sampling before suckling colostrum.Results The results showed that maternal MET supplementation tended to decrease the IUGR incidence and increased the average weaning weight of piglets.Moreover,maternal MET supplementation significantly reduced the plasma concentrations of isoleucine,cysteine,urea,and total amino acids in sows and newborn pig-lets.It also increased lactase and sucrase activity in the jejunum of newborn piglets.MET addition resulted in lower ileal methionine synthase activity and increased betaine homocysteine S-methyltransferase activity in the ileum of newborn piglets.DNA methylation analysis of the ileum showed that MET supplementation increased the methyla-tion level of DNA CpG sites in the ileum of newborn piglets.Down-regulated differentially methylated genes were enriched in folic acid binding,insulin receptor signaling pathway,and endothelial cell proliferation.In contrast,up-regulated methylated genes were enriched in growth hormone receptor signaling pathway and nitric oxide biosyn-thetic process.Conclusions Maternal MET supplementation can reduce the incidence of IUGR and increase the weaning litter weight of piglets,which may be associated with better intestinal function and methylation status. 展开更多
关键词 ILEUM Intrauterine growth restriction Methyl donor METHYLATION SOWS
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基于“剪枝+并行”FP-Growth算法的密切接触人员快速追踪技术的研究
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作者 刘聪 《现代信息科技》 2023年第2期34-37,41,共5页
利用“剪枝+并行”式FP-Growth优化算法,通过提升计算精度和速度的方式对疫情发生地区确诊患者的密接人员、次密接人员和同时空关联人员实行快速精准的排查。与传统的FP-Growth算法相比,“剪枝+并行”式FP-Growth算法的计算性能得到显... 利用“剪枝+并行”式FP-Growth优化算法,通过提升计算精度和速度的方式对疫情发生地区确诊患者的密接人员、次密接人员和同时空关联人员实行快速精准的排查。与传统的FP-Growth算法相比,“剪枝+并行”式FP-Growth算法的计算性能得到显著提升。通过对某地区测试者7天内行迹及相关联人员信息进行时间和准确方面的测试比较发现,计算时长缩短了近30%,准确率由82%提升至91%。实验表明,利用优化后的FP-Growth算法能够较好地满足疫情发生地区快速精准确定相关联人员的要求。 展开更多
关键词 fp-growth算法 关联性 快速精准
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Dynamic changes of rumen microbiota and serum metabolome revealed increases in meat quality and growth performances of sheep fed bio‑fermented rice straw 被引量:1
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作者 Yin Yin Kyawt Min Aung +6 位作者 Yao Xu Zhanying Sun Yaqi Zhou Weiyun Zhu Varijakshapanicker Padmakumar Zhankun Tan Yanfen Cheng 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第3期1207-1226,共20页
Background Providing high-quality roughage is crucial for improvement of ruminant production because it is an essential component of their feed.Our previous study showed that feeding bio-fermented rice straw(BF)improv... Background Providing high-quality roughage is crucial for improvement of ruminant production because it is an essential component of their feed.Our previous study showed that feeding bio-fermented rice straw(BF)improved the feed intake and weight gain of sheep.However,it remains unclear why feeding BF to sheep increased their feed intake and weight gain.Therefore,the purposes of this research were to investigate how the rumen micro-biota and serum metabolome are dynamically changing after feeding BF,as well as how their changes influence the feed intake,digestibility,nutrient transport,meat quality and growth performances of sheep.Twelve growing Hu sheep were allocated into 3 groups:alfalfa hay fed group(AH:positive control),rice straw fed group(RS:negative control)and BF fed group(BF:treatment).Samples of rumen content,blood,rumen epithelium,muscle,feed offered and refusals were collected for the subsequent analysis.Results Feeding BF changed the microbial community and rumen fermentation,particularly increasing(P<0.05)relative abundance of Prevotella and propionate production,and decreasing(P<0.05)enteric methane yield.The histomorphology(height,width,area and thickness)of rumen papillae and gene expression for carbohydrate trans-port(MCT1),tight junction(claudin-1,claudin-4),and cell proliferation(CDK4,Cyclin A2,Cyclin E1)were improved(P<0.05)in sheep fed BF.Additionally,serum metabolome was also dynamically changed,which led to up-regulating(P<0.05)the primary bile acid biosynthesis and biosynthesis of unsaturated fatty acid in sheep fed BF.As a result,the higher(P<0.05)feed intake,digestibility,growth rate,feed efficiency,meat quality and mono-unsaturated fatty acid concentration in muscle,and the lower(P<0.05)feed cost per kg of live weight were achieved by feeding BF.Conclusions Feeding BF improved the growth performances and meat quality of sheep and reduced their feed cost.Therefore,bio-fermentation of rice straw could be an innovative way for improving ruminant production with mini-mizing production costs. 展开更多
关键词 Bio-fermentation growth rate Meat quality METABOLOME MICROBIOTA Rice straw
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Role of transforming growth factor-βin peripheral nerve regeneration 被引量:3
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作者 Zihan Ding Maorong Jiang +4 位作者 Jiaxi Qian Dandan Gu Huiyuan Bai Min Cai Dengbing Yao 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期380-386,共7页
Injuries caused by trauma and neurodegenerative diseases can damage the peripheral nervous system and cause functional deficits.Unlike in the central nervous system,damaged axons in peripheral nerves can be induced to... Injuries caused by trauma and neurodegenerative diseases can damage the peripheral nervous system and cause functional deficits.Unlike in the central nervous system,damaged axons in peripheral nerves can be induced to regenerate in response to intrinsic cues after reprogramming or in a growth-promoting microenvironment created by Schwann cells.However,axon regeneration and repair do not automatically result in the restoration of function,which is the ultimate therapeutic goal but also a major clinical challenge.Transforming growth factor(TGF)is a multifunctional cytokine that regulates various biological processes including tissue repair,embryo development,and cell growth and differentiation.There is accumulating evidence that TGF-βfamily proteins participate in peripheral nerve repair through various factors and signaling pathways by regulating the growth and transformation of Schwann cells;recruiting specific immune cells;controlling the permeability of the blood-nerve barrier,thereby stimulating axon growth;and inhibiting remyelination of regenerated axons.TGF-βhas been applied to the treatment of peripheral nerve injury in animal models.In this context,we review the functions of TGF-βin peripheral nerve regeneration and potential clinical applications. 展开更多
关键词 MYELINATION nerve repair and regeneration NEURITE NEUROINFLAMMATION peripheral nerve injury Schwann cell transforming growth factor-β Wallerian degeneration
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Activation of endogenous neurogenesis and angiogenesis by basic fibroblast growth factor-chitosan gel in an adult rat model of ischemic stroke 被引量:4
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作者 Hongmei Duan Shulun Li +11 位作者 Peng Hao Fei Hao Wen Zhao Yudan Gao Hui Qiao Yiming Gu Yang Lv Xinjie Bao Kin Chiu Kwok-Fai So Zhaoyang Yang Xiaoguang Li 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期409-415,共7页
Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactiv... Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactive materials can repair the damage caused by ischemic stroke by activating endogenous neurogenesis and angiogenesis is still unknown.In this study,we applied chitosan gel loaded with basic fibroblast growth factor to the stroke cavity 7 days after ischemic stroke in rats.The gel slowly released basic fibroblast growth factor,which improved the local microenvironment,activated endogenous neural stem/progenitor cells,and recruited these cells to migrate toward the penumbra and stroke cavity and subsequently differentiate into neurons,while enhancing angiogenesis in the penumbra and stroke cavity and ultimately leading to partial functional recovery.This study revealed the mechanism by which bioactive materials repair ischemic strokes,thus providing a new strategy for the clinical application of bioactive materials in the treatment of ischemic stroke. 展开更多
关键词 adult endogenous neurogenesis ANGIOGENESIS basic fibroblast growth factor-chitosan gel CHITOSAN functional recovery ischemic stroke neural stem cell newborn neuron
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Delineation of urban growth boundary based on FLUS model under the perspective of land use evaluation in hilly mountainous areas 被引量:1
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作者 ZHANG Yunping LIN Jianping +3 位作者 HUANG Yimin CHEN Zebin ZHU Chenhui YUAN Hao 《Journal of Mountain Science》 SCIE CSCD 2024年第5期1647-1662,共16页
With rapid economic development,the size of urban land in China is expanding dramatically.The Urban Growth Boundary(UGB)is an expandable spatial boundary for urban construction in a certain period in order to control ... With rapid economic development,the size of urban land in China is expanding dramatically.The Urban Growth Boundary(UGB)is an expandable spatial boundary for urban construction in a certain period in order to control the urban sprawl.Reasonable delineation of UGB can inhibit the disorderly spread of urban space and guide the normal development of the city.It is of practical significance for the construction of green urban space.The study utilizes GIS technology to establish a land construction suitability evaluation system for Nankang city,which is experiencing rapid urban expansion,and outlines the preliminary UGB under the future land use simulation(FLUS)model.At the same time,considering the coupled coordination of"Production-Living-Ecological Space",and based on the suitability evaluation,we revised the preliminary UGB by combining the advantages of the patch-generating land use simulation(PLUS)model and the convex hull model to delineate the final UGB.The results show that:1)the comprehensive score of the evaluation of the suitability of the construction of land from high to low shows the distribution of the center of the city to the surrounding circle type spread,the center of the city has the highest suitability score.The results of convex hull model show that the urban expansion type of Nankang is epitaxial.In the future,the urban expansion will mainly occur in the northern part of the city.The PLUS model predicts an increase of 3359.97 hm^(2)of construction land in Nankang by 2035,of which 2022.97 hm^(2)is urban construction land.2)The FLUS model has a prediction accuracy of 86.3%and delineates a preliminary UGB area of 9215.07 hm^(2).3)We used the results of the construction suitability evaluation,PLUS model simulation results,and convex hull model predictions to revise the originally delineated UGB.The final delineated UGB area is 8895.67 hm^(2)and it is capable of meeting the future development of the study area.The results of the delineation can promote sustainable urban development,and the delineation methodology can provide a reference basis for the preparation of territorial spatial planning. 展开更多
关键词 Urban sprawl FLUS model Spatial correction Urban growth boundary Sustainable development
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