BACKGROUND Complex hypospadias is a surgical challenge.AIM To present the long-term outcomes of two-stage repair of complex hypospadias using a scrotal septal flap.METHODS This was a retrospective study of patients wi...BACKGROUND Complex hypospadias is a surgical challenge.AIM To present the long-term outcomes of two-stage repair of complex hypospadias using a scrotal septal flap.METHODS This was a retrospective study of patients with complex hypospadias who were operated on between January 1st,2001,and January 1st,2019,at a single hospital using a scrotal septal flap(two-stage surgery)or prepuce flap(one-stage surgery;control group).In the scrotal group,the urethra was first repaired using oral mucosa;in the second stage,a scrotal septal flap was used as a second impermeable layer.Maximal/average urinary flow rates after surgery were compared.All patients were followed for≥6 mo(range:6-96 mo).RESULTS Ninety-seven patients were included(46 in the scrotal group and 51 in the prepuce group).The maximal urinary flow rate was 15.4±2.1 mL/s in the scrotal group and 14.3±3.0 mL/s in the control group(P=0.035).The average urinary flow rate was 8.4±2.3 mL/s in the scrotal group and 7.5±1.5 mL/s in the control group(P=0.019).The proportion of patients achieving good therapeutic effects was higher in the scrotal group than in the control group[24(52.2%)vs 16(31.4%),P=0.042;34(73.9%)vs 25(49.0%),P=0.014].The scrotal flap two-stage surgery was independently associated with a higher maximal urinary flow rate(OR=2.416,95%CI:1.026-5.689,P=0.044)and with a higher average flow rate(OR=2.484,95%CI:1.054-5.854,P=0.038).CONCLUSION In complex hypospadias,a scrotal septal flap could be a versatile and reliable option for resurfacing the penis.展开更多
<span style="font-family:Verdana;">Fournier’s syndrome is a poly microbial necrotizing fasciitis, of severe evolution of the perineum and external genitals. </span><b><b><span sty...<span style="font-family:Verdana;">Fournier’s syndrome is a poly microbial necrotizing fasciitis, of severe evolution of the perineum and external genitals. </span><b><b><span style="font-family:Verdana;">Objectives:</span></b><span style="font-family:Verdana;"></span></b><span style="font-family:Verdana;"> We report the experience of the service in the management of Fournier gangrene of the external genital organs by inguinal flap pediculated in front of the loss of significant substances of the scrotum.</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">Patients and method: This was a mono-centric retrospective study from January 2008 to August 2021 in the General Surgery Department of the Bocar Sidi Sall University Hospital (CHU BSS) in Kati. It focused on patients treated for Fournier gangrene of external genitals.</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The variables studied were age, sex, blood count, germs encountered, the antibiogram, duration of evolution, reconstruction of the scrotum by pedicle flap, and morbidity. <b></b></span><b><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"></span></b></span><b> </b><span style="font-family:Verdana;">During the study period we collected 5 cases of Fournier gangrene of external genitals in the service. The average age was 57.6 years and all the patients were male. The average duration of evolution was 5 days for an average age of 57.6 years. All patients were male. <i></i></span><i><i><span style="font-family:Verdana;">Echerichia coli</span></i><span style="font-family:Verdana;"></span></i> (<i><i><span style="font-family:Verdana;">E.</span></i><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">coli</span></i><span style="font-family:Verdana;"></span></i>)<span> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">was the frequently observed germ followed by <i></i></span><i><i><span style="font-family:Verdana;">Enterobacter fécalis</span></i><span style="font-family:Verdana;"></span></i> (<i></i></span><i><i><span style="font-family:Verdana;">E. fecalis</span></i><span style="font-family:Verdana;"></span></i>).<span style="font-family:;" "=""> </span><span style="font-family:Verdana;">They were resistant to the usual antibiotics. The germs were 100% sensitive to imipenem</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;"> and nitrofurantoin, 70% to gentamycin. The wide necrosectomy followed 3 weeks later by the inguinal flap pedicular plasty greatly improved the surgical procedures. Conclusion: Fournier’s syndrome is a medical surgical emergency whose prognosis is strongly related to early management.</span>展开更多
基金Special Research Fund for Plastic Surgery Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,No.B2018009Beijing Municipal Science&Technology Commission-Functional Urethral Reconstruction of Hypospadias by Tissue Transplantation,No.Z161100000516015.
文摘BACKGROUND Complex hypospadias is a surgical challenge.AIM To present the long-term outcomes of two-stage repair of complex hypospadias using a scrotal septal flap.METHODS This was a retrospective study of patients with complex hypospadias who were operated on between January 1st,2001,and January 1st,2019,at a single hospital using a scrotal septal flap(two-stage surgery)or prepuce flap(one-stage surgery;control group).In the scrotal group,the urethra was first repaired using oral mucosa;in the second stage,a scrotal septal flap was used as a second impermeable layer.Maximal/average urinary flow rates after surgery were compared.All patients were followed for≥6 mo(range:6-96 mo).RESULTS Ninety-seven patients were included(46 in the scrotal group and 51 in the prepuce group).The maximal urinary flow rate was 15.4±2.1 mL/s in the scrotal group and 14.3±3.0 mL/s in the control group(P=0.035).The average urinary flow rate was 8.4±2.3 mL/s in the scrotal group and 7.5±1.5 mL/s in the control group(P=0.019).The proportion of patients achieving good therapeutic effects was higher in the scrotal group than in the control group[24(52.2%)vs 16(31.4%),P=0.042;34(73.9%)vs 25(49.0%),P=0.014].The scrotal flap two-stage surgery was independently associated with a higher maximal urinary flow rate(OR=2.416,95%CI:1.026-5.689,P=0.044)and with a higher average flow rate(OR=2.484,95%CI:1.054-5.854,P=0.038).CONCLUSION In complex hypospadias,a scrotal septal flap could be a versatile and reliable option for resurfacing the penis.
文摘<span style="font-family:Verdana;">Fournier’s syndrome is a poly microbial necrotizing fasciitis, of severe evolution of the perineum and external genitals. </span><b><b><span style="font-family:Verdana;">Objectives:</span></b><span style="font-family:Verdana;"></span></b><span style="font-family:Verdana;"> We report the experience of the service in the management of Fournier gangrene of the external genital organs by inguinal flap pediculated in front of the loss of significant substances of the scrotum.</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">Patients and method: This was a mono-centric retrospective study from January 2008 to August 2021 in the General Surgery Department of the Bocar Sidi Sall University Hospital (CHU BSS) in Kati. It focused on patients treated for Fournier gangrene of external genitals.</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The variables studied were age, sex, blood count, germs encountered, the antibiogram, duration of evolution, reconstruction of the scrotum by pedicle flap, and morbidity. <b></b></span><b><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"></span></b></span><b> </b><span style="font-family:Verdana;">During the study period we collected 5 cases of Fournier gangrene of external genitals in the service. The average age was 57.6 years and all the patients were male. The average duration of evolution was 5 days for an average age of 57.6 years. All patients were male. <i></i></span><i><i><span style="font-family:Verdana;">Echerichia coli</span></i><span style="font-family:Verdana;"></span></i> (<i><i><span style="font-family:Verdana;">E.</span></i><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">coli</span></i><span style="font-family:Verdana;"></span></i>)<span> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">was the frequently observed germ followed by <i></i></span><i><i><span style="font-family:Verdana;">Enterobacter fécalis</span></i><span style="font-family:Verdana;"></span></i> (<i></i></span><i><i><span style="font-family:Verdana;">E. fecalis</span></i><span style="font-family:Verdana;"></span></i>).<span style="font-family:;" "=""> </span><span style="font-family:Verdana;">They were resistant to the usual antibiotics. The germs were 100% sensitive to imipenem</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;"> and nitrofurantoin, 70% to gentamycin. The wide necrosectomy followed 3 weeks later by the inguinal flap pedicular plasty greatly improved the surgical procedures. Conclusion: Fournier’s syndrome is a medical surgical emergency whose prognosis is strongly related to early management.</span>