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Improving beef hamburger quality and fatty acid profiles through dietary manipulation and exploitation of fat depot heterogeneity
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作者 Cletos Mapiye Jennifer L Aalhus +6 位作者 Payam Vahmani David C Rolland Timothy A McAllister Hushton C Block Bethany Uttaro Spencer D Proctor Michael E R Dugan 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2015年第1期111-121,共11页
Background: Hamburger is the most consumed beef product in North America, but lacks in nutritional appeal due to its high fat content and high proportion of saturated fatty acids (SFA). Objectives of the present st... Background: Hamburger is the most consumed beef product in North America, but lacks in nutritional appeal due to its high fat content and high proportion of saturated fatty acids (SFA). Objectives of the present study were to improve the FA profiles of hamburgers made with perirenal fat (PRF) and subcutaneous fat (SCF) when feeding steers different diets along with examining differences in sensory attributes and oxidative stability. Diets included a control diet containing 70:30 red clover silage: barley based concentrate, a diet containing sunflower-seed (SS) substituted for barley, and diets containing SS with 15% wheat dried distillers' grain with solubles (DDGS-15) or 30% DDGS (DDGS-30). Hamburgers were made from triceps brachii and either PRF or SCF (80:20 w/w). Results: Perirenal fat versus SCF hamburgers FA had 14.3% more (P 〈0.05) 18:0, 11.8% less cis (c)9-18:1 (P 〈0.05), and 1.82% more total trdns (t)-18:1 mainly in the form of tl 1-18:1. During sensory evaluation, PRF versus SCF hamburgers had greater (P 〈0.05) mouth coating, but the difference was less than one panel unit. Examining effects of steer diet within PRF hamburgers, feeding the SS compared to the control diet increased (P 〈0.05) t-18:1 by 2.89% mainly in the form of tl 1-18:1, feeding DGGS-15 diet led to no further changes (P 〉0.05), but feeding DDGS-30 diet reduced the proportions of (P 〈0.05) of t-18:1 chiefly tl 1-18:1. Feeding SS and DDGS diets had small but significant (P 〈0.05) effects on hamburger sensory attributes and oxidative stability. Conclusions: Feeding high-forage diets including SS and 15% DDGS, and taking advantage of the FA heterogeneity between fat depots offers an opportunity to differentially enhance beef hamburgers with 18:2n-6 biohydrogenation products (Le., t11-18:1) with potential human health benefits without compromising their sensory attributes and oxidative stability during retail display. 展开更多
关键词 BEEF DDGS fat depot fatty acids Sensory attributes Oxidative stability
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The Profile of Abundant and Essential Fatty Acids in Depot Fat Varies More in Kiwi (<i>Apteryx mantelli</i>) than in Other Avian Species
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作者 Murray Alan Potter Charlotte Jane Minson Roger Graham Lentle 《Food and Nutrition Sciences》 2013年第9期158-164,共7页
Direct and dendrographic comparison of the profiles of abundant fatty acids in depot fat was unable to separate 10 avian species on a basis of their overall proportions but was able to distinguish broad dietary groups... Direct and dendrographic comparison of the profiles of abundant fatty acids in depot fat was unable to separate 10 avian species on a basis of their overall proportions but was able to distinguish broad dietary groups or those in a habitat with distinctive nutritional characteristics such as avian marine carnivores. In all species considered, including North Island brown kiwi (Apteryx mantelli), oleic (C18:1) and palmitic acids (C16:0) were most abundant. The relative proportions of linolenic (C18:3) acid were 4% or lower across all species, while the relative proportions of palmitoleic acid (C18:0) were less than 7% in nine of the avian species, with the exception being the insectivorous red-eyed vireo (Vireo olivaceous). The levels of linoleic acid (C18:2) were lower in avian marine carnivores than in avian herbivores, insectivores, and omnivores. Whilst the mean values of the individual fatty acids in fat from various avian species were separated by hierarchical cluster analysis, the wide range of values of each fatty acid precluded any correlation of clustering with any known variation in dietary items. Similarly, the wide range in fatty acid composition of kiwi fat rendered it unhelpful in determining the optimum composition of the captive diet. 展开更多
关键词 fatty Acids Composition depot fat Diet Apteryx mantelli AVIAN
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心包脂肪体积的研究进展及临床应用价值 被引量:3
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作者 李江 孙钢 《医学影像学杂志》 2013年第6期977-979,共3页
心包脂肪组织(pericardial adipose tissue,PAT)特殊的解剖学分布、复杂的生理生化特性以及与冠状动脉粥样硬化的密切相关性使其成为世界性研究热点。PAT体积增加已被公认是动脉粥样硬化性疾病和代谢综合征的一个重要危险因素。PAT体积... 心包脂肪组织(pericardial adipose tissue,PAT)特殊的解剖学分布、复杂的生理生化特性以及与冠状动脉粥样硬化的密切相关性使其成为世界性研究热点。PAT体积增加已被公认是动脉粥样硬化性疾病和代谢综合征的一个重要危险因素。PAT体积与冠状动脉粥样硬化的发生发展密切相关,对内脏脂肪组织的鉴别和评价至关重要,故PAT体积对冠状动脉粥样硬化性心脏病的风险预测及诊断具有极高的临床应用价值,并可能成为冠心病的治疗靶点。 展开更多
关键词 心包脂肪 内脏脂肪库 冠状动脉粥样硬化 代谢综合征
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肥胖对动脉粥样硬化的影响 被引量:14
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作者 孙恒 齐潇雁 肖新华 《中国动脉硬化杂志》 CAS 2019年第10期829-834,共6页
肥胖是一种由多种因素引起的慢性代谢性疾病,表现为体内脂肪堆积过多和(或)脂肪分布异常。动脉粥样硬化的主要病变特征是动脉内膜下脂质沉积,伴有平滑肌细胞和胶原纤维增多,逐步发展形成动脉粥样硬化性斑块。大量的基础和临床研究表明,... 肥胖是一种由多种因素引起的慢性代谢性疾病,表现为体内脂肪堆积过多和(或)脂肪分布异常。动脉粥样硬化的主要病变特征是动脉内膜下脂质沉积,伴有平滑肌细胞和胶原纤维增多,逐步发展形成动脉粥样硬化性斑块。大量的基础和临床研究表明,肥胖能够加剧动脉粥样硬化的发生危险,其可能的机制包括脂代谢异常、胰岛素抵抗、炎症、内皮功能障碍等,但是迄今为止肥胖对动脉粥样硬化的影响机制尚未完全清楚。本文将重点从心外膜及血管周围的异位脂肪沉积、新型脂肪因子、脂肪组织相关外泌体、脂肪棕色化等新的观点阐述肥胖对动脉粥样硬化的影响,为肥胖致动脉粥样硬化的防治提供一些新的思路。 展开更多
关键词 肥胖 异位脂肪沉积 外泌体 棕色化 动脉粥样硬化
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肥胖者胰岛素抵抗与总体脂、局部体脂关系的研究 被引量:69
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作者 陈蕾 贾伟平 +4 位作者 项坤三 陆俊茜 包玉倩 薛凤仙 陆蔚 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2001年第5期276-279,共4页
目的 应用扩展高胰岛素 正葡萄糖钳夹技术 ,研究正常糖耐量中国人中正常体重者及超重 /肥胖者胰岛素敏感性的异同 ,以及体脂含量及分布与胰岛素敏感性的关系。方法 对 2 2例居住上海地区中国人 ,其中正常体重组 (BMI <2 5kg/m2 ) ... 目的 应用扩展高胰岛素 正葡萄糖钳夹技术 ,研究正常糖耐量中国人中正常体重者及超重 /肥胖者胰岛素敏感性的异同 ,以及体脂含量及分布与胰岛素敏感性的关系。方法 对 2 2例居住上海地区中国人 ,其中正常体重组 (BMI <2 5kg/m2 ) 9例 ,超重 /肥胖组 (BMI≥ 2 5kg/m2 ) 13例 ,进行扩展高胰岛素 正葡萄糖钳夹试验 ,并应用核磁共振技术 (MRI)测定局部体脂。结果  (1)超重 /肥胖组较之正常体重组胰岛素介导的葡萄糖利用率降低〔(3 .37± 0 .15 )mg·kg-1·min-1比 (5 .86± 0 .6 5 )mg·kg-1·min-1,P <0 .0 1〕 ,以糖原合成障碍为主〔(1.5 1± 0 .15 )mg·kg-1·min-1比 (3.17± 0 .6 2 )mg·kg-1·min-1,P <0 .0 1〕。 (2 )超重 /肥胖组胰岛素抑制脂氧化及血游离脂肪酸水平的作用减弱。(3)局部体脂中以腹内脂肪增加对胰岛素敏感性的影响最显著 (r =- 0 .80 ,P <0 .0 1)。结论中国人正常糖耐量、超重 /肥胖个体胰岛素敏感性下降 。 展开更多
关键词 葡萄糖钳制技术 肥胖 胰岛素敏感性 体脂含量 局部体脂
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β3-肾上腺能受体基因Trp64Arg突变对中国人体脂、血糖与血脂水平、胰岛素分泌及作用的影响 被引量:14
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作者 项坤三 贾伟平 +6 位作者 陆惠娟 郑泰山 陆俊茜 唐峻岭 丁炜 孙多奇 李杰 《中华医学遗传学杂志》 CAS CSCD 北大核心 1998年第6期337-340,共4页
目的明确β3-肾上腺能受体(ADRB3)基因Trp64Arg突变对中国人体脂含量与分布、血糖脂水平、胰岛素分泌及作用有无影响。方法在308例中国人[非糖尿病(ND)161例,2型糖尿病(DM)147例]中检测ADRB... 目的明确β3-肾上腺能受体(ADRB3)基因Trp64Arg突变对中国人体脂含量与分布、血糖脂水平、胰岛素分泌及作用有无影响。方法在308例中国人[非糖尿病(ND)161例,2型糖尿病(DM)147例]中检测ADRB3基因Trp64Arg突变基因型,并测体块指数(BMI)、理想体重百分数(PDW)、葡萄糖兴奋前后血糖、胰岛素、C肽、游离脂肪酸以及空腹血脂谱和血压。结果(1)中国人ADRB3基因Trp64Arg突变中Arg64等位基因频率与日本人相近,略高于高加索人。(2)ND组中Trp64Arg突变与各临床情况变异均无相关。(3)DM者中Trp64Arg突变与BMI(P=0.019)、PDW(P=0.001)、腰围(P=0.045)相关。在女性DM中,该突变与BMI(P=0.001)、PDW(P=0.001)、腰围(P=0.023)相关更明显,尚与腹部及皮下脂肪面积(P=0.032及P=0.023)相关。女性DM伴肥胖、超重及体重正常者中Arg64等位基因频率分别为21%、14%及4%(P=0.026)。Logistic回归分析表明,与Trg64Arg突变唯一独立相关的临床变量是BMI(P=0.0027)。? 展开更多
关键词 糖尿病 ADRB3 体脂 血糖 血脂 胰岛素 基因突变
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