Study on Female Sexual Dysfunction in Type 2 Diabetic Chinese Women

Objective To investigate the female sexual dysfunction(FSD)in type 2 diabetes patients,by comparing the sexual function between type 2 diabetic women and non-diabetic women with Female Sexual Function Index(FSFI).Methods 215 type 2 diabetic women and 107 age-matched non-diabetes women were enrolled with similar backgrounds.Their sexual functions were evaluated with FSFI.Metabolic parameters such as body mass index,blood lipid profile,hemoglobin AlC,plasma glucose were also collected.Results Total score of FSFI of the type 2 diabetic women were significantly lower than that of the non-diabetic controls(18.27±8.96 vs.23.02±5.78,P=0.000).Scores of the FSFI domains(desire,arousal,lubrication,orgasm,satisfaction,pain)of the type 2 diabetic group were also lower than those of the control group.According to the FSD criterion(FSFI〈25)available in China,the percentage of FSD in the type 2 diabetic group was significantly higher than that of the control group(79.2%vs.55.0%,P〈0.001).These trends seemed more prominent in pre-menopause subgroups.The logistic regression analysis indicated that age and diabetes were independent risk factors of FSD.Body Mass Index(BMI)also had influence in the diabetes group.Conclusion Findings from this study showed that there are more FDS in Chinese type 2 diabetic women than in their non-diabetic counterparts,especially in pre-menopause participants.

Female Sexual Dysfunction among Chinese Primiparous Women

Objective: To compare sexual function between primiparous women who underwent cesarean section (CS) and those who delivered vaginally. Methods: This cross-sectional study was conducted from October 2011 to April 2012 in Beijing, China. The target population included women aged 18 - 45 years who had given birth only once at least 6 months prior. The questionnaire was self-administered including female sexual function measured using the Female Sexual Function Index (FSFI). Data were analyzed using R software with the significance level of 0.05. Results: A total of 1456 participants were included and 102 women (7.0%) declined. The median age of the participants was 35 years. The median time interval after childbirth was 6 years. The median FSFI score was 26.9 and prevalence of female sexual dysfunction (FSD) was 34.2%. Both the FSFI scores and the proportions of individuals with sexual disorders were similar between women undergoing CS and those having vaginal delivery for both individual domains and the full scale. Conclusion: There were insignificant differences in female sexual function scores and FSD prevalence between women undergoing CS versus vaginal delivery.

The Use of Natural Products for the Treatment of Female Sexual Dysfunction: A Systematic Review of Randomized Clinical Trials

Female sexual dysfunction (FSD) affects 40% of the world’s females, most of which are disorders linked to desire or interest/excitement. Whilst all types of therapy that attempt to improve female sexual desire have long been established, the results are contradictory. Objective: To analyze all available evidence to validate the effectiveness of natural therapies in the treatment of FSD. Method: The study was registered at http://www.prospero.org (CRD42019127700). We searched the Institute for Scientific Information Web of Knowledge, MEDLINE, Pubmed, Scopus and Cochrane databases for all articles published in peer- reviewed journals in April 2019 (in any language). The PICOS standard is women with FSD;(intervention) of any type of Natural therapy;(outcome) primary outcome: frequency of changes, severity, and average mean scores on sexual symptoms measured with a validated instrument, secondary outcome: quality of life;(study design) and randomized clinical trial (RCT). Results: The literature search strategy identified 95 articles, 81 of which were excluded at the different search stages. Finally, we systematically reviewed 15 RCTs, 11 of which referred to primary FSD, and four of which analyzed women with drug-induced FSD (DFSD). Most of them analyzed hypoactive sexual desire disorder. Although differences related to placebo were found in most people, the majority of the studies are considered to be of poor quality and low external effectiveness. Conclusion: Although the quality of the evidence is not high, most natural product interventions appear to improve FSD, particularly hypoactive sexual desire disorders including those categorized as primary and drug-induced.

Female Sexual Dysfunction in Elfayoum Governorate

Introduction: female sexual dysfunction (FSD) is a complex and poorly understood condition that affects females of all ages. Female sexual dysfunction has been a cyclic rather than a linear process that emphasizes biologic, psychological, social, hormonal, and environmental factors. Female sexual dysfunction is a high prevalent disorder reaching up to 60% of females with reported higher levels in postmenopausal. Aim of the work: was to estimate prevalence of FSD and its related factors in Elfayoum city. Subject and Method: This study was a cross sectional descriptive study conducted in Elfayoum city included 508 married females (above 21 years old) during the period from September 2016 to March 2017. Results: The prevalence of FSD among studied group was 61.2% versus 38.8% had normal sexual function, desire dysfunction was 42.3%, arousal dysfunction was 39.2%, lubrication dysfunction was 25%, orgasm dysfunction was 58.5%, satisfaction dysfunction was 58.1% and pain was 43.3%. There was statistically significant negative correlation between Female Sexual Function Index (FSFI) score and each of female and husband age, duration of marriage, and number of children. Low mean of FSFI score was found among females with irregular menstrual cycle, using contraceptive, not pregnant, mutilated and females who’s their husband had erectile or ejaculation disorders. Conclusion and recommendation: High prevalence of FSD among females in Elfayoum governorate. Many factors are found to affect FSD as FGM, each of female and husband age, duration of marriage, and number of children.

Assessment of Female Sexual Dysfunction in Patients with Premenopausal Female Pattern Hair Loss

Introduction: Female sexual dysfunction (FSD) is a serious problem that affects negatively the quality of life, interpersonal relationships and female self- confidence and might be a direct cause of psychopathological disturbances. Female pattern hair loss (FPHL) is a common cosmetically disturbing condition affecting many women with social and psychological consequences. Aim of the Work: Assessment of the relationship between female sexual dysfunction and Female pattern hair loss in premenopausal females. Methods: A case-control study was carried on 47 female patients with FPHL and 43 age- matched control women without FPHL among premenopausal women attending dermatology and Andrology outpatient’s clinics, Suez Canal University hospital during the period from May 2018 to January 2019. History taking, clinical examination and hormonal investigation (Free Testosterone, Total Testosterone, and SHBG) were performed to all participants in the study. Main Outcome Measures: The Female Sexual Function Index (FSFI) was used to assess the key aspects of female sexual function in patients and controls. FPHL was diagnosed and graded by Ludwig’s classification. Results: Mean age of patients group was 30.12 ± 5.49 years, Regarding FPHL grading, 55.3%, 42.6% & 2.1% of patients were grades 1, 2 and 3 Ludwig’s classification respectively. FSD was found in 44.7% of patients while it was 44.2% in control group (P > 0.05). FSFI score in patients group was 26.40 ± 4.61 and in control group was 27.05 ± 3.12 (P > 0.05). Correlation between FSD prevalence and grade of FPHL by Ludwig’s classification was statistically insignificant. FSD was significantly compromised by increasing age and parity in patients and control groups (P < 0.05). Conclusions: The present study suggests that FSD was not significantly related to FPHL. Increased age and parity may have strong impact on sexual function in premenopausal women, while androgen hormones levels were not determinant factor.

Therapeutic Approach in Female Sexual Dysfunctions in an Outpatient Clinic of Sexology in the Public Health System: A Longitudinal and Prospective Study

INTRODUCTION: Sexuality is one of the parameters of quality of life, and it is essential to include care for sexual dysfunctions in primary health care. OBJECTIVE: To evaluate the therapeutic approach in female sexual dysfunction in a public health outpatient clinic. DESIGN: A prospective cohort of women with sexual dysfunctions in an outpatient clinic of sexology in the Public Health System. The Female Sexual Function Index (FSFI) and scored 0 - 10 their sexual satisfaction were applied at the beginning and end of the follow-up. RESULTS: Eighty-nine women were included with a median age of 45 years, 69 (77.5%) had less than 11 years of schooling and 95.5% lived with a partner. The main reasons for referral for follow-up at the outpatient clinic of sexuality were dysfunction of hypoactive sexual desire disorder in 67.4% and pain related to sexual function in 46%. The average number of consultations was five and the main therapeutic interventions were guidance and clarification on sexuality (86.5%), use of topical estrogen (56.2%), and relaxation techniques (37.1%). All FSFI-19 domains had better post-intervention rates (p ≤ 0.005). Considering the domains of the FSFI-19, the medians of desire, arousal, lubrication, orgasm, pleasure and pain were higher in the post-intervention period in relation to the pre-intervention period (p ≤ 0.0001 for all analysis). In addition, the score given by the participant on their sexual satisfaction was higher at the post-intervention time compared to the pre-intervention period (p ≤ 0.0001). CONCLUSION: In public health, even with the care being performed by different professionals in each consultation, we conclude that through simple interventions, it is possible to improve the sexualities of the women attended. Still, offering care in sexuality is fundamental as part of primary health care and the training of medical professionals.

Sexual Dysfunction among Chinese Nurses:Prevalence and Predictors

This study aimed to estimate the prevalence of and identify the factors influencing female sexual dysfunction （FSD） among Chinese nurses. A cross-sectional survey was conducted from March 2013 to May 2014 among 6 hospitals in Suzhou, China. In total, 2,030 married female nurses were included in the analysis.

Sexual Satisfaction Is Reduced in the Female Patient and Sexually Intimate Partners Following Cancer Therapy

As cancer survival has continued to improve, cancer patients and their sexually intimate partner (SIP) are confronted with a number of issues including sexual function and overall sexual health. Our study objective was to assess changes in sexual function in women undergoing cancer treatment and their SIP, and attempt to identify areas of needed support and improvement. In this questionnaire-based observational study, females (n = 11) completed a Female Sexual Function Index (FSFI) and for SIP’s (n = 11), a Brief Sexual Function Inventory (BSFI). Level of satisfaction prior to and within 3 months following treatment with surgery, chemotherapy and/or radiation was compared. Mean pre-and post-treatment total (30.7 ± 2.7 vs. 23.2 ± 3.7, p < 0.001) and individual FSFI domains were significantly different for desire (4.2 ± 0.6 vs. 2.6 ± 0.6, p < 0.001), arousal (4.9 ± 0.4 vs. 3.5 ± 0.7, p = 0.001), lubrication (5.5 ± 0.4 vs. 4.5 ± 0.8, p = 0.006), orgasm (5.0 ± 0.6 vs. 3.8 ± 0.7, p = 0.001), satisfaction (5.3 ± 0.6 vs. 3.5 ± 0.9, p < 0.001), though no differences were noted with dyspareunia. For SIP’s, BSFI domain scores for level of satisfaction were significantly lower following partner treatment of SIPs (3.5 ± 5.2 vs. 2.5 ± 5.2, p = 0.004). Overall, female sexual dysfunction was identified in 9% of patients prior to cancer treatment and 91% (n = 11, p < 0.001) following treatment. In conclusion, cancer treatment significantly affects sexual function in female cancer patients and their SIPs. While long term effects on sexual dysfunction are still unclear, short-term health care strategies including treatment, counseling, and appropriate referral for cancer patients and their SIPs should not be overlooked.

Female Sexual Function after Surgical Treatment of Urinary Incontinence

Introduction: Urinary incontinence is a common problem that can affect the quality of life of women of all ages and can negatively influence the exercise of sexuality. Aim: The aim of this study was to compare sexual function of women before and after surgical treatment for urinary incontinence. Method: The sample consisted of 38 women with urinary incontinence and surgical treatment (Burch or Sling procedure). The Female Sexual Function Index (FSFI) was used to evaluate sexual dysfunction before and after surgical treatment. Results: The mean age of the women in the study was 48 ± 8.8 years, and 58% were 50 years old or younger. By analyzing FSFI, it was observed that the majority of subjects had an overall index of sexual dysfunction (score < 26 points) before surgery. The desire and arousal domains improved significantly after surgery for all women included in the study. It was also observed that women with higher levels of education had more positive results related to desire. Conclusions: In our sample, in general, sexual function improved after surgical treatment of urinary incontinence, regardless of technique used, particularly in the discounter and pain domain. There was a substantial improvement of the sexual function among women who had presented with cystocele. Desire and arousal improved significantly after surgery, very likely due to the improvement of self-esteem after surgery.

Sexual dysfunctions and their treatment in liver diseases

Sexual dysfunction(SD)is a prevalent but very commonly ignored aspect in the treatment of liver diseases and cirrhosis.The etiology of SD is multifactorial and therefore treatment strategies are complex,especially in females.Phosphodiesterase inhibitors are useful and effective in erectile dysfunction in males but in females,no single drug is available for SD,therefore multimodal treatment is required depending upon the cause.The foremost and fundamental requirement in both genders is to be stress-free and have adequate control of liver diseases.Improved quality of life is helpful in improving SD and vice versa is also true.Therefore,patients suffering from liver diseases should come forward and ask for treatment for SD,and physicians should actively enquire about SD while history taking and evaluating these patients.SD results in deterioration of quality of life,and both are modifiable and treatable aspects of liver diseases,which are never addressed actively,due to social taboos and fears of SD treatment in the presence of liver diseases.The diagnosis of SD does not require costly investigations,as the diagnosis can be established based on validated questionnaires available for both genders,therefore detailed targeted history taking using questionnaires is essential.Data are emerging in this area but is still at an early stage.More studies should be dedicated to SD in liver diseases.

Relationship between Female Sexual Function and Depression or Anxiety in Japan

Background: Sexual dysfunction is sexual complaints or disorders. There are various causes, but the onset leads to deterioration of relationships and quality of life with partners. There is still a deep-rooted awareness that sexuality is a secret in Japan. Aim: This study aims to clarify the relationship between female sexual function and depression or anxiety. Method: Four hundred and fifty-eight Japanese healthy women who worked in four randomly selected medical institutions in Okinawa Prefecture in Japan from March to May 2012 were asked to agree to a consent form of their own free will and participate in self-reported questionnaires. For their evaluation, the Female Sexual Function Index (FSFI;Rosen et al. 2000, which includes the six domains of desire, arousal, lubrication, orgasm, pain, and satisfaction) and the Kessler Psychological Distress Scale (K6;Kessler, 2002, which includes the following six items: felt nervous, hopeless, restless or fidgety, worthless, depressed, and felt that everything was an effort) was used. Moreover, participants’ characteristics showed age, marriage, menopause, annual income, and drinking. In addition, JMP16.2 and R 4.2.0 was used to perform Pearson’s chi-square test, Fisher’s exact test, Mann-Whitney U test, Kruskal-Wallis test, Steel-Dwass test, Spearman’s Rank-Order Correlation, and Cronbach’s alpha. This study was approved by the university and the medical institutional review board (IRB). Results: 178 women were included in the final analysis, and the median (IQR, interquartile range) was 39 (32 - 48) years old, and the mean ± SD (standard deviation) was 40.2 ± 10.4 years old. The median (IQR) and mean ± SD of FSFI Total Score were 22.0 (9.3 - 26.6) and 19.2 ± 9.6. The median (IQR) and the mean ± SD of K6 Total Score were 3 (0 - 7) and 4.2 ± 4.5. 16% of all women with a K6 Total Score of 10 and more, and 5% of all women with a K6 Total Score of 13 and more considered a serious mental illness. There was no clear association between female sexual function and depression or anxiety in all health worker participants between FSFI Total Score and K6 Total Score by Spearman’s Rank-Order Correlation Coefficient (ρ). However, there was a moderate correlation between the K6 Total Score and the FSFI Total Score in health worker participants with a K6 Total Score of 11 or more (n =19, ρ = ?0.62, P = 0.005). Moreover, there was a weak correlation between them in both married and drinking women or married and non-menopausal women. In the Mann-Whitney U test where few participants had morbid depression, significant relationships were found in the association between a sexual function with high depression or anxiety, whereas the low group had a K6 cut-off value of 11. Conclusion: Female sexual morbidity for high depression or anxiety should be managed with interventions. Especially, the intervention for decreasing female sexual function in the K6 Total Score of 11 or more will be needed, and a randomized study is required for more evidence.

Effective of Behavioral Treatment Combined with Psychological Counseling for Female Coital Disorder of Chinese

Objective: To explore the effects of the behavioral treatment combined with psychological counseling on female coital disorder in China. Methods: One hundred and sixteen female patients with coital disorder were divided into sexual behavior training combined with psychological counseling group (group A, 59 cases) and psychological counseling alone group (group B, 57 cases). Results: Forty-five cases cured (76.27%), eight eases improved (13.56%), and six cases invalid (10.17%), the general rate of effectiveness being 89.83% in group A while eleven cases cured (19.30%), twenty-one cases improved (36.84%), and twenty-five cases invalid (43.86%), the general rate of effectiveness being 56.14% in group B. The curative effect of group A was better than group B (P Conclusions: The behavioral treatment combined with psychological counseling is significantly effective in treating female coital disorder than psychological counseling alone and its long term follow-up results show that most of patients were satisfied with their sex life. However, the response of behavioral treatment of some patients who had bad experience on sexual things in the progress of their growing up or had long course of disease were not so good which deserves our special attention in the future study.

骶神经磁刺激联合生物反馈在以产后性交痛为主的FSD患者中的应用效果

目的:探讨骶神经磁刺激联合生物反馈在以产后性交痛为主的女性性功能障碍(FSD)患者中的应用效果。方法:选取2023年1—12月毕节市七星关区妇幼保健院收治的200例以产后性交痛为主的FSD患者作为研究对象,根据康复治疗方案的不同将研究对象分为观察组和对照组,各100例。对照组采用常规盆底功能康复治疗,观察组采用骶神经磁刺激联合生物反馈治疗,比较两组盆底肌力评分、性功能评分、盆底肌电值及雌激素水平。结果:观察组治疗15 d、30 d盆底肌力评分高于对照组,差异有统计学意义(P<0.05);观察组治疗30 d女性性功能调查量表(FSFI)评分高于对照组,差异有统计学意义(P<0.05);观察组治疗后盆底肌电值正常比例及雌二醇、孕酮和促卵泡激素水平高于对照组,差异有统计学意义(P<0.05)。结论:骶神经磁刺激联合生物反馈治疗可提高以产后性交痛为主要表现的FSD患者的盆底肌力评分、性功能评分、盆底肌电值正常比例及雌激素水平。

Prevalence and Factors Associated with Female Sexual Dysfunction in Beijing, China

Background： Female sexual dysfunction （FSD） is a highly prevalent and often underestimated problem. However, large-scale, population-based epidemiological surveys of FSD are scarce in China. The present study was conducted to evaluate the prevalence and the potential risk factors of FSD across a selection of social groups in Beijing, China, based on the Female Sexual Function Index （FSFI）. Methods： A cross-sectional study based on the multiple-stage cluster sampling was performed with adult women throughout the Dongcbeng and Shunyi districts of Beijing. The Chinese version of FSFI was used, as well as questions on demographic characteristics, the disease-related context, and social relationships. Results： A total of 6000 consecutive women entered this study, with an actual response from 5024 women, corresponding to a response rate of 83.7%. A total of 4697 （78.3%） questionnaires were effective. The prevalence of adult FSD in Beijing was 2973 （63.3%） using a score of 26.55 as the boundary value, whereas the total mean FSFI score was 23.92 ~ 6.37. However, 1423 （30.3%） women did not seek help. By multivariate logistic regression analysis, the possible potential risk factors included age （odds ratio [OR] = 1.051 ）, dissatisfaction with the spouse＇s sexual ability （OR = 3.520）, poor marital affection （OR = 2.087）, spouse sexual difficulties （OR = 1.720）, dissatisfaction with married life （OR = 1.476）, living in a rural area （OR = 1.292）, chronic pelvic pain （OR = 1.261）, chronic disease （OR = 1.534）, previous pelvic surgery （OR = 1.605）, vaginal delivery （OR = 2.285）, lower education （OR = 3.449） and postmenopausal （OR = 3.183）. Conclusions： As suggested by the FSFI scores, female sexual problems are highly prevalent in Beijing. Dissatisfaction with the spouse＇s sexual ability, poor marital affection, sexual difficulties of the spouse, dissatisfaction with the marriage, rural life, CPP, and postmenopausal were conceivable risk factors for FSD in Beijing women.

Better renal replacement therapy to improve sexual function in female patients with end-stage renal disease:A cross-sectional study

Background Sexual dysfunction is commonly observed in patients with end-stage renal disease(ESRD).Sexual dysfunction in correlation with ESRD is associated with physiological and psychological problems resulting in low sexual desire,arousal,difficulties in achieving orgasm,and pain during intercourse.Studies on female sexual dysfunction(FSD)in correlation with renal replacement therapy are limited,and previous studies reporting contradictive results have indicated that the best modality for providing better outcomes(especially on FSD)remains unclear.Thus,this study aimed to compare the sexual function between female patients with ESRD who were on continuous ambulatory peritoneal dialysis(CAPD)and those on hemodialysis(HD).Materials and methods This study enrolled female patients who were randomly selected from the urology and renal division of the Internal Medicine Outpatient Clinic of our hospital from January 2020 to August 2021 and divided into the following groups:predialysis,HD,CAPD,and control groups.The participants were asked to fill out the Female Sexual Function Index(FSFI)questionnaires,and their data were recorded and analyzed using GraphPad Prism 9.0.0.Results Of the 280 patients,200 female patients were included in this study.The rate of FSD(cutoff:26.55)was 42%in the control group,72%in the predialysis group,62%in the CAPD group,and 66%the in HD group.The control group had a higher mean score in all parameters(p<0.05).The total FSFI mean score indicated no significant difference(p>0.05)between the patients on HD and those on CAPD;the mean of each point was almost identical except for satisfaction,which was higher among patients on CAPD(p<0.05).Significant differences in the components of desire,arousal,orgasm,and satisfaction were observed between the groups.Conclusions Patients on CAPD had better FSFI scores than the female patients with ESRD who were on HD,and the scores of both groups of patients were better than those of the predialysis group.

五倍可利洁娜霜用于女性性功能障碍(FSD)及性器官保健的研究

目的:探讨五倍可利洁娜霜对FSD中性交不适、性交疼痛的治疗及性器官保健方法。方法:对918例性交不适、性交疼痛患者采用五倍可利洁娜治疗,直接涂擦外阴皮肤、阴道口内外,一疗程(20天)后观察治疗结果,经统计处理后进行疗效分析。结果:性交不适、性交疼痛,一疗程痊愈率分别为:84.95%、78.54%;总有效率分别为:97.85%、95.75%。结论:五倍可利洁娜霜对FSD中的性交不适和性交疼痛有良好的治疗效果,特别是对因阴道干涩、性交疼痛难忍而长期终止性生活的情况,有助于性机能的恢复、重启。在应用中未发现任何毒副作用,不含激素类成份,可广泛用于FSD中相关病症的治疗,或用于围绝经期及有性活动人群的性器官保健。

Sexual Function in Pregnant Women in the Public Health System

Introduction: Pregnancy is a unique situation and involves changes in sexuality. The aim is to evaluate sexual function and satisfaction in pregnant women under prenatal care provided by the public health system. Method: Cross-sectional study with pregnant women receiving ambulatory care in the public health system in the Southern region of Brazil conducted between November 2014 and September 2015. Results: 283 pregnant women were studied. The mean age was 27.7 ± 6.3 years;64% were white and 31.1% were nulliparous. In the total sample, 8.50% were in the first trimester of pregnancy, 37.4% were in the second trimester, and 54.1% were in the third trimester. The rate of global sexual dysfunction (score 26 points) was 55.5%, following the application of The Female Sexual Function Index (FSFI). Sexual dysfunction was significantly more prevalent in the third trimester (62%) compared to the first (33.3%) and second (50.9%) trimesters (p = 0.015). There was a significant difference in all domains, except in the desired domain, according to the trimester. Pregnant women in the third trimester showed significantly lower scores compared to those in the first trimester in the domains with significance. Conclusion: The prevalence of sexual dysfunction among pregnant women in the public system was high. Knowing that more than 50% of the pregnant women presented sexual dysfunction, it is essential to approach sexuality during prenatal care involving the couple.

度洛西汀在女性慢性盆腔痛治疗中的作用研究

目的研究度洛西汀在女性慢性盆腔痛治疗中的作用。方法选取金华市中心医院和金华市妇幼保健院2021年6月至2023年6月盆腔疼痛患者126例,随机分成对照组和观察组,剔除失访及未完成治疗12例,对照组56例,观察组58例,对照组给予盆底电刺激治疗,观察组在对照组治疗基础上应用度洛西汀,两组均治疗3个月,治疗前后应用视觉模拟评分法(Visual analogue scale,VAS)、盆底功能障碍问卷简要版-20(Pelvic floor dysfunction inventory-20,PFDI-20)、盆底器官脱垂/尿失禁性生活问卷-12(Pelvic organ prolapse-urinary incontinence sexual function questionnaire-12,PISQ-12)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)及医院焦虑抑郁量表(Hospital anxiety and depression scale,HAD)观察两组患者治疗前后病情的改善状况。结果治疗前两组VAS、PFDI-20、PISQ-12、PSQI、HAD评分比较,差异无统计学意义(P>0.05),治疗3个月分别对比VAS(观察组:1.20±0.16,对照组:1.51±0.20,P<0.05)、PFDI-20(观察组:5.69±5.4,对照组:8.95±4.27,P<0.05)、PISQ-12(观察组:40.79±3.11,对照组:30.86±5.88,P<0.05)、PSQI(观察组:7.79±1.39,对照组:10.59±1.95,P<0.05)及HAD(观察组:6.21±1.74,对照组:9.29±2.38,P<0.05),差异有统计学意义。结论度洛西汀在女性慢性盆腔痛治疗过程中有助于改善患者疼痛、焦虑、抑郁状态,提高患者生活及睡眠质量,对女性慢性盆腔痛有改善作用,同时对患者性生活质量也有明显改善作用。

绝经过渡期和绝经后期女性睾酮水平对女性性功能的影响

目的探索绝经过渡期和绝经后期女性雄激素水平对性功能的影响。方法募集2023年1月至2023年12月首次来首都医科大学附属北京妇产医院就诊的绝经过渡期和绝经后期女性,纳入符合纳入标准和排除标准的女性450例,收集人口统计学资料和既往病史、应用女性性功能指数(female sexual function index,FSFI)量表、改良Kupperman评分量表评价女性性功能和围绝经期症状;测量人体测量学指标;检测实验室指标包括总睾酮、游离睾酮、生物活性睾酮、4-雄烯二酮和雌激素。采用相关和回归分析探索雄激素水平对女性性功能的影响。结果与绝经过渡期相比,绝经后期女性FSFI量表的各维度得分和总分明显下降(P<0.05)。多元线性回归分析显示生物活性睾酮水平与性唤起得分(β=0.190,P<0.05)和FSFI总分(β=0.178,P<0.05)呈正相关,游离睾酮水平与性欲(β=0.166,P<0.05)、性满意度(β=0.176,P<0.05)、FSFI总分(β=0.126,P<0.05)呈正相关。改良Kupperman评分与FSFI总分及各维度得分呈负相关(P<0.05)。结论女性性功能障碍与游离睾酮和生物活性睾酮水平下降有关,与总睾酮水平无关。

阴道哑铃结合热敏灸、Kegel运动训练治疗产后盆底功能障碍的效果

目的分析阴道哑铃结合热敏灸、Kegel运动训练治疗产后盆底功能障碍(PFD)的效果。方法选择2021年1月至2023年12月诊治的PFD初产妇118例,依照随机抽签法分为观察组和对照组,每组59例。对照组采用阴道哑铃结合Kegel运动训练,观察组给予阴道哑铃结合热敏灸、Kegel运动训练。比较2组治疗效果,干预前后阴道收缩力、盆底肌力、盆底功能、女性性功能指数、尿失禁分级情况。结果观察组总有效率[98.31%(58/59)]高于对照组[84.75%(50/59)](P<0.05)。干预后,观察组阴道收缩力相关指标、盆底肌力、性功能指数均高于对照组(P<0.01);干预后,观察组盆底功能相关评分低于对照组(P<0.01);干预后,观察组尿失禁分级优于对照组(P<0.05)。结论PFD患者经阴道哑铃结合热敏灸、Kegel运动训练干预盆底肌力、盆底功能、尿失禁分级得到了改善,女性性功能指数、阴道收缩力得到了提升,效果较好。