AIM:To compare the clinical outcomes of wavefront guided femtosecond LASIK(WFG LASIK)and conventional femtosecond LASIK(NWFG LASIK)in eyes with myopia and myopia astigmatism.METHODS:This was a retrospective,nonrandomi...AIM:To compare the clinical outcomes of wavefront guided femtosecond LASIK(WFG LASIK)and conventional femtosecond LASIK(NWFG LASIK)in eyes with myopia and myopia astigmatism.METHODS:This was a retrospective,nonrandomized,comparative investigation enrolling 236 eyes of 122 patients(18-50 y)with low&moderate and high myopia.The WFG group including 97 eyes(50 patients)undergone WFG LASIK and the NWFG group including 139 eyes(72 patients)undergone conventional LASIK.Mean efficacy index,high order aberrations(HOAs),pupil size and the quality of visual questionnaire were evaluated 6 mo postoperatively.RESULTS:There is no difference between WFG group(-0.054±0.049 in logMAR)and NWFG group(-0.040±0.056)in uncorrected distance visual acuity(UDVA)postoperatively.The myopia astigmatism is higher in WFG group than that in NWFG group(P<0.05).However,the mean efficacy index(MEI)in the WFG group(1.09±0.106)is better than that in the NWFG group(1.036±0.124;P<0.001).Increased HOAs were observed in NWFG group(0.30±0.196)than that in WFG group(0.146±0.188;P<0.001).The pupil size is larger in WFG group(5.15±0.76 mm)than that in NWFG group(4.32±0.52 mm).The patients are satisfied with the clinical surgery,yet WFG group showed better visual quality using the questionnaire survey.Meanwhile,high myopia would result in worse MEI,HOAs and visual quality than low&moderate myopia.CONCLUSION:WFG and NWFG FS-LASIK are both effective and safe procedures to correct low&moderate and high myopia,but WFG FS-LASIK gives a better postoperative MEI,aberrometric control and predictable outcome.Meanwhile,WFG FS-LASIK is better than NWFG FS-LASIK in correction of myopia astigmatism.Low&moderate myopia allow better clinical outcomes than high myopia using any surgical method.展开更多
AIM: To assess the loss of contrast sensitivity (CS) function for INTRACOR or intrastromal femtosecond laser presbyopia procedure to conventional LASIK procedures.METHODS: Patients were recruited from a refractive...AIM: To assess the loss of contrast sensitivity (CS) function for INTRACOR or intrastromal femtosecond laser presbyopia procedure to conventional LASIK procedures.METHODS: Patients were recruited from a refractive surgery center for either INTRACOR or conventional LASIK. INTRACOR was performed on 8 eyes and LASIK was performed for 40 eyes in an overlapping period. Pre-operative evaluation and post-operative follow up for up to three months was done. Drops of CS in 4 spatial frequency (3 cpd, 6 cpd, 12 cpd and 18 cpd) right before and 3mo after the surgery were compared by Wilcoxon signed ranks test.RESULTS: For INTRACOR, CS threshold showed significant drop at both glare and non-glare condition, the drop was seen in all 4 spatial frequency. The averaged loss over the 4 spatial frequencies 3mo after surgery was 1.18 for non-glare and 0.71 for glare. For LASIK the CS threshold drop was most significant in 12 cpd for glare.CONCLUSION: INTRACOR procedure produces a gain of near vision for presbyopia patients but also introduces a high lost of contrast sensitivity plus worsen of vision quality. Pre-surgical patient selection and advise should be given with specific regards to night driving and glare conditions.展开更多
AIM:To compare the speed of visual recovery following myopic thin-flap LASIK with four femtosecond lasers.METHODS:Eighty-eight eyes of 46 patients who were consecutively scheduled for bilateral LASIK with the Intra ...AIM:To compare the speed of visual recovery following myopic thin-flap LASIK with four femtosecond lasers.METHODS:Eighty-eight eyes of 46 patients who were consecutively scheduled for bilateral LASIK with the Intra Lase FS60(Group 1),Femto LDV Crystal Line(Group 2),Wavelight FS200(Group 3)and Visu Max(Group 4)femtosecond lasers were enrolled in.Monocular uncorrected distance visual acuity(UDVA),best-corrected distant visual acuity(CDVA),refraction,contrast sensitivity and higher-order aberrations(HOAs)were evaluated at 1,3d,1wk and 1mo postoperatively.RESULTS:Sixteen eyes(72.7%)achieved 20/16 and 8eyes(36.4%)were 20/12.5 at 1d in Group 2,which was significantly more than other 3 groups.At 1wk,20 eyes(90.9%)achieved 20/16 in Groups 2 and 4.At 1mo,20 eyes(90.9%)achieved 20/16 in Group 2 and Group 4,which were significantly more than other two groups.While by1 mo,the difference of the residual spherical equivalent(SE)was not statistically significant among 4 groups(P=0.121).The induction of spherical aberration(SA)were significantly less for Groups 2,3,4 than for Group 1 one day after surgery(P=0.015).The differences among 4groups were not statistically significant before and after surgery on every time points(all P〉0.05).CONCLUSION:The thin-flap LASIK procedure using the Femto LDV Crystal Line and Visu Max femtosecond laser show faster visual performance recovery.展开更多
目的:对比分析飞秒激光和角膜板层刀行准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后患者的视觉质量及角膜瓣变化。方法:选取2009-03/2012-03将接受飞秒激光35例70眼患者和接受角膜板层刀的患者45例90眼进行对比研...目的:对比分析飞秒激光和角膜板层刀行准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后患者的视觉质量及角膜瓣变化。方法:选取2009-03/2012-03将接受飞秒激光35例70眼患者和接受角膜板层刀的患者45例90眼进行对比研究,两组术后视觉质量和角膜瓣进行对比。结果:视觉质量比较:两组患者所行的手术均有显著的可预测性、有效性及安全性,且术后像差和对比敏感度及视力差异不显著,组间差异无统计学意义(P>0.05);角膜瓣比较:两组患者在水平方向的角膜瓣厚度组间差异无统计学意义(P>0.05)。结论:飞秒激光和角膜板层刀行LASIK术后具有良好的视觉效果,且角膜瓣厚度差异不显著,值得临床推广使用。展开更多
基金National Natural Science Foundation of China(No.81800624,No.81700839,No.82171081)the“Chen Guang”Project the Shanghai Municipal Education Commission and the Shanghai Education Development Foundation(No.18CG40)+1 种基金234 Mountain Climbing Plan of Changhai Hospital(No.2020YXK048,No.2020YXK058)“Sailing Project”Naval Medical University。
文摘AIM:To compare the clinical outcomes of wavefront guided femtosecond LASIK(WFG LASIK)and conventional femtosecond LASIK(NWFG LASIK)in eyes with myopia and myopia astigmatism.METHODS:This was a retrospective,nonrandomized,comparative investigation enrolling 236 eyes of 122 patients(18-50 y)with low&moderate and high myopia.The WFG group including 97 eyes(50 patients)undergone WFG LASIK and the NWFG group including 139 eyes(72 patients)undergone conventional LASIK.Mean efficacy index,high order aberrations(HOAs),pupil size and the quality of visual questionnaire were evaluated 6 mo postoperatively.RESULTS:There is no difference between WFG group(-0.054±0.049 in logMAR)and NWFG group(-0.040±0.056)in uncorrected distance visual acuity(UDVA)postoperatively.The myopia astigmatism is higher in WFG group than that in NWFG group(P<0.05).However,the mean efficacy index(MEI)in the WFG group(1.09±0.106)is better than that in the NWFG group(1.036±0.124;P<0.001).Increased HOAs were observed in NWFG group(0.30±0.196)than that in WFG group(0.146±0.188;P<0.001).The pupil size is larger in WFG group(5.15±0.76 mm)than that in NWFG group(4.32±0.52 mm).The patients are satisfied with the clinical surgery,yet WFG group showed better visual quality using the questionnaire survey.Meanwhile,high myopia would result in worse MEI,HOAs and visual quality than low&moderate myopia.CONCLUSION:WFG and NWFG FS-LASIK are both effective and safe procedures to correct low&moderate and high myopia,but WFG FS-LASIK gives a better postoperative MEI,aberrometric control and predictable outcome.Meanwhile,WFG FS-LASIK is better than NWFG FS-LASIK in correction of myopia astigmatism.Low&moderate myopia allow better clinical outcomes than high myopia using any surgical method.
文摘AIM: To assess the loss of contrast sensitivity (CS) function for INTRACOR or intrastromal femtosecond laser presbyopia procedure to conventional LASIK procedures.METHODS: Patients were recruited from a refractive surgery center for either INTRACOR or conventional LASIK. INTRACOR was performed on 8 eyes and LASIK was performed for 40 eyes in an overlapping period. Pre-operative evaluation and post-operative follow up for up to three months was done. Drops of CS in 4 spatial frequency (3 cpd, 6 cpd, 12 cpd and 18 cpd) right before and 3mo after the surgery were compared by Wilcoxon signed ranks test.RESULTS: For INTRACOR, CS threshold showed significant drop at both glare and non-glare condition, the drop was seen in all 4 spatial frequency. The averaged loss over the 4 spatial frequencies 3mo after surgery was 1.18 for non-glare and 0.71 for glare. For LASIK the CS threshold drop was most significant in 12 cpd for glare.CONCLUSION: INTRACOR procedure produces a gain of near vision for presbyopia patients but also introduces a high lost of contrast sensitivity plus worsen of vision quality. Pre-surgical patient selection and advise should be given with specific regards to night driving and glare conditions.
文摘AIM:To compare the speed of visual recovery following myopic thin-flap LASIK with four femtosecond lasers.METHODS:Eighty-eight eyes of 46 patients who were consecutively scheduled for bilateral LASIK with the Intra Lase FS60(Group 1),Femto LDV Crystal Line(Group 2),Wavelight FS200(Group 3)and Visu Max(Group 4)femtosecond lasers were enrolled in.Monocular uncorrected distance visual acuity(UDVA),best-corrected distant visual acuity(CDVA),refraction,contrast sensitivity and higher-order aberrations(HOAs)were evaluated at 1,3d,1wk and 1mo postoperatively.RESULTS:Sixteen eyes(72.7%)achieved 20/16 and 8eyes(36.4%)were 20/12.5 at 1d in Group 2,which was significantly more than other 3 groups.At 1wk,20 eyes(90.9%)achieved 20/16 in Groups 2 and 4.At 1mo,20 eyes(90.9%)achieved 20/16 in Group 2 and Group 4,which were significantly more than other two groups.While by1 mo,the difference of the residual spherical equivalent(SE)was not statistically significant among 4 groups(P=0.121).The induction of spherical aberration(SA)were significantly less for Groups 2,3,4 than for Group 1 one day after surgery(P=0.015).The differences among 4groups were not statistically significant before and after surgery on every time points(all P〉0.05).CONCLUSION:The thin-flap LASIK procedure using the Femto LDV Crystal Line and Visu Max femtosecond laser show faster visual performance recovery.
文摘目的:对比分析飞秒激光和角膜板层刀行准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后患者的视觉质量及角膜瓣变化。方法:选取2009-03/2012-03将接受飞秒激光35例70眼患者和接受角膜板层刀的患者45例90眼进行对比研究,两组术后视觉质量和角膜瓣进行对比。结果:视觉质量比较:两组患者所行的手术均有显著的可预测性、有效性及安全性,且术后像差和对比敏感度及视力差异不显著,组间差异无统计学意义(P>0.05);角膜瓣比较:两组患者在水平方向的角膜瓣厚度组间差异无统计学意义(P>0.05)。结论:飞秒激光和角膜板层刀行LASIK术后具有良好的视觉效果,且角膜瓣厚度差异不显著,值得临床推广使用。