Deep learning-based magnetic resonance imaging reconstruction for improving the image quality of reduced-field-of-view diffusionweighted imaging of the pancreas

BACKGROUND It has been reported that deep learning-based reconstruction(DLR)can reduce image noise and artifacts,thereby improving the signal-to-noise ratio and image sharpness.However,no previous studies have evaluated the efficacy of DLR in improving image quality in reduced-field-of-view(reduced-FOV)diffusionweighted imaging(DWI)[field-of-view optimized and constrained undistorted single-shot(FOCUS)]of the pancreas.We hypothesized that a combination of these techniques would improve DWI image quality without prolonging the scan time but would influence the apparent diffusion coefficient calculation.AIM To evaluate the efficacy of DLR for image quality improvement of FOCUS of the pancreas.METHODS This was a retrospective study evaluated 37 patients with pancreatic cystic lesions who underwent magnetic resonance imaging between August 2021 and October 2021.We evaluated three types of FOCUS examinations:FOCUS with DLR(FOCUS-DLR+),FOCUS without DLR(FOCUS-DLR−),and conventional FOCUS(FOCUS-conv).The three types of FOCUS and their apparent diffusion coefficient(ADC)maps were compared qualitatively and quantitatively.RESULTS FOCUS-DLR+(3.62,average score of two radiologists)showed significantly better qualitative scores for image noise than FOCUS-DLR−(2.62)and FOCUS-conv(2.88)(P<0.05).Furthermore,FOCUS-DLR+showed the highest contrast ratio and 600 s/mm^(2)(0.72±0.08 and 0.68±0.08)and FOCUS-DLR−showed the highest CR between cystic lesions and the pancreatic parenchyma for the b-values of 0 and 600 s/mm2(0.62±0.21 and 0.62±0.21)(P<0.05),respectively.FOCUS-DLR+provided significantly higher ADCs of the pancreas and lesion(1.44±0.24 and 3.00±0.66)compared to FOCUS-DLR−(1.39±0.22 and 2.86±0.61)and significantly lower ADCs compared to FOCUS-conv(1.84±0.45 and 3.32±0.70)(P<0.05),respectively.CONCLUSION This study evaluated the efficacy of DLR for image quality improvement in reduced-FOV DWI of the pancreas.DLR can significantly denoise images without prolonging the scan time or decreasing the spatial resolution.The denoising level of DWI can be controlled to make the images appear more natural to the human eye.However,this study revealed that DLR did not ameliorate pancreatic distortion.Additionally,physicians should pay attention to the interpretation of ADCs after DLR application because ADCs are significantly changed by DLR.

A trajectory shaping guidance law with field-of-view angle constraint and terminal limits

In this paper, a trajectory shaping guidance law,which considers constraints of field-of-view(FOV) angle, impact angle, and terminal lateral acceleration, is proposed for a constant speed missile against a stationary target. First, to decouple constraints of the FOV angle and the terminal lateral acceleration, the third-order polynomial with respect to the line-ofsight(LOS) angle is introduced. Based on an analysis of the relationship between the looking angle and the guidance coefficient,the boundary of the coefficient that satisfies the FOV constraint is obtained. The terminal guidance law coefficient is used to guarantee the convergence of the terminal conditions. Furthermore, the proposed law can be implemented under bearingsonly information, as the guidance command does not involve the relative range and the LOS angle rate. Finally, numerical simulations are performed based on a kinematic vehicle model to verify the effectiveness of the guidance law. Overall, the work offers an easily implementable guidance law with closed-form guidance gains, which is suitable for engineering applications.

Near-Range Large Field-of-View Three-Dimensional Photon-Counting Imaging with a Single-Pixel Si-Avalanche Photodiode

Large field-of-view（FoV） three-dimensional（3 D） photon-counting imaging is demonstrated with a single-pixel single-photon detector based on a Geiger-mode Si-avalanche photodiode. By removing the collecting lens（CL）before the detector, the FoV is expanded to ±10°. Thanks to the high detection efficiency, the signal-to-noise ratio of the imaging system is as high as 7.8 dB even without the CL when the average output laser pulse energy is about 0.45 pJ/pulse for imaging the targets at a distance of 5 m. A 3 D image overlaid with the reflectivity data is obtained according to the photon-counting time-of-flight measurement and the return photon intensity.

Study of a millimeter-wave squint indirect holographic algorithm suitable for imaging with large field-of-view

In this paper a millimeter-wave （MMW） squint indirect holographic method is presented, which is suitable for imaging with a large field-of-view. The proposed system employs the squint operation mode to remove the background and twin- image interferences, which achieves a similar effect to off-axis holography but leaves out the large-aperture quasi-optical component. The translational scanning manner enables a large field of view and ensures the image uniformity, which is difficult to realize in off-axis holography. In addition, a corresponding imaging algorithm for the presented scheme is developed to reconstruct the image from the recorded hologram. Some imaging results on typical objects, obtained with electromagnetic simulation, demonstrate good performance of the imaging scheme and validate the effectiveness of the image reconstruction algorithm.

Calibration of Camera with Large Field-of-View Based on Flexible Planar Target

For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve this problem,a calibration method based on flexible planar target is proposed.In this method,distortion factor is firstly acquired by the invariance of cross ratio,and existing feature points are adjusted with the distortion factor.Then,a large number of points that will be used for the calibration are constructed with the adjusted feature points.Simultaneously,Tsai method is modified so as to reduce the complexity of calibration,which makes the process linear.The simulation and real experiments show that the method proposed in this paper is simple,linear,accurate and robust,and the precision of this method is close to that of Tsai method using abundant points.The method can satisfy the requirement of high precision calibration for camera with large field-of-view.

Understanding wide field-of-view flat lenses:an analytical solution[Invited]

Wide field-of-view(FOV)optics are widely used in various imaging,display,and sensing applications.Conventional wide FOV optics rely on complicated lens assembly comprising multiple elements to suppress coma and other Seidel aberrations.The emergence of flat optics exemplified by metasurfaces and diffractive optical elements(DOEs)offers a promising route to expand the FOV without escalating complexity of optical systems.To date,design of large FOV flat lenses has been relying upon iterative numerical optimization.Here,we derive,for the first time,to the best of our knowledge,an analytical solution to enable computationally efficient design of flat lenses with an ultra-wide FOV approaching 180°.This analytical theory further provides critical insights into working principles and otherwise non-intuitive design trade-offs of wide FOV optics.

Large-field objective lens for multi-wavelength microscopy at mesoscale and submicron resolution

Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.

Command filtered integrated estimation guidance and control for strapdown missiles with circular field of view

In this paper,an integrated estimation guidance and control(IEGC)system is designed based on the command filtered backstepping approach for circular field-of-view(FOV)strapdown missiles.The threedimensional integrated estimation guidance and control nonlinear model with limited actuator deflection angle is established considering the seeker's FOV constraint.The boundary time-varying integral barrier Lyapunov function(IBLF)is employed in backstepping design to constrain the body line-of-sight(BLOS)in IEGC system to fit a circular FOV.Then,the nonlinear adaptive controller is designed to estimate the changing aerodynamic parameters.The generalized extended state observer(GESO)is designed to estimate the acceleration of the maneuvering targets and the unmatched time-varying disturbances for improving tracking accuracy.Furthermore,the command filters are used to solve the"differential expansion"problem during the backstepping design.The Lyapunov theory is used to prove the stability of the overall closed-loop IEGC system.Finally,the simulation results validate the integrated system's effectiveness,achieving high accuracy strikes against maneuvering targets.

Optimal three-dimensional impact time guidance with seeker’s field-of-view constraint

This paper proposes a new three-dimensional optimal guidance law for impact time control with seeker’s Field-of-View(FOV) constraint to intercept a stationary target. The proposed guidance law is devised in conjunction with the concept of biased Proportional Navigation Guidance(PNG). The guidance law developed leverages a nonlinear function to ensure the boundedness of velocity lead angle to cater to the seeker’s FOV limit. It is proven that the impact time error is nullified in a finite-time under the proposed method. Additionally, the optimality of the biased command is theoretically analyzed. Numerical simulations confirm the superiority of the proposed method and validate the analytic findings.

Atmospheric Correction of SeaWiFS Data for the Retrieval of SuspendedSediment in East China Coastal Waters

The data of SeaWiFS (Sea-Viewing Wide Field-of-View Sensor), installed on SeaStar, has been used to generate SSC (suspended sediment concentration) of complex and turbid coastal waters in China. In view of the problems of the SeaDAS (SeaWiFS Data Analysis System) algorithm applied to China coastal waters, a new atmospheric correction algorithm is discussed, developed, and used for the SSC of East China coastal waters. The advantages of the new algorithm are described through the comparison of the results from different algorithms.

Flexible reduced field of view magnetic resonance imaging based on single-shot spatiotemporally encoded technique

In many ultrafast imaging applications, the reduced field-of-view（r FOV） technique is often used to enhance the spatial resolution and field inhomogeneity immunity of the images. The stationary-phase characteristic of the spatiotemporallyencoded（SPEN） method offers an inherent applicability to r FOV imaging. In this study, a flexible r FOV imaging method is presented and the superiority of the SPEN approach in r FOV imaging is demonstrated. The proposed method is validated with phantom and in vivo rat experiments, including cardiac imaging and contrast-enhanced perfusion imaging. For comparison, the echo planar imaging（EPI） experiments with orthogonal RF excitation are also performed. The results show that the signal-to-noise ratios of the images acquired by the proposed method can be higher than those obtained with the r FOV EPI. Moreover, the proposed method shows better performance in the cardiac imaging and perfusion imaging of rat kidney, and it can scan one or more regions of interest（ROIs） with high spatial resolution in a single shot. It might be a favorable solution to ultrafast imaging applications in cases with severe susceptibility heterogeneities, such as cardiac imaging and perfusion imaging. Furthermore, it might be promising in applications with separate ROIs, such as mammary and limb imaging.

A distributed cooperative guidance law for salvo attack of multiple anti-ship missiles

The consensus problem of impact time is addressed for multiple anti-ship missiles. A new distributed cooperative guidance law with the form of biased proportional navigation guidance （BPNG） is presented. The proposed guidance law employs the available measurements of relative impact time error as the feedback information to achieve the consensus of impact time among mis- siles and, by exploiting the special structure of the biased cooperative control term, it can handle the seeker＇s field-of-view （FOV） constraint. The proposed scheme ensures convergence to consensus of impact time under either fixed or switching sensing/communication network, and the topological requirements are less restrictive than those in the existing results. Numerical examples are provided to illustrate the effectiveness of the proposed guidance law.

Integrated cooperative guidance framework and cooperative guidance law for multi-missile

An integrated cooperative guidance framework for multi-missile cooperatively attacking a single stationary target is proposed in this paper by combining both the centralized and decentralized communication topologies. Once missiles are distributed into several groups, missiles within a single group communicate with the centralized leader-follower framework, while the leaders from different groups communicate using the nearest-neighbor topology. To implement the integrated cooperative guidance framework, a group of Finite-Time Cooperative Guidance（FTCG） laws considering the saturation constraint on FOV（FTCG-FOV） are firstly derived within the centralized leader-follower framework to satisfy the communication topology of missiles in a single group.Then, an improved sequential approach is developed to adapt the FTCG-FOV to satisfy the communication topology between groups. The numerical simulations demonstrate the effectiveness and high efficiency of the integrated cooperative guidance framework and the cooperative guidance laws, as well as the superiority of the developed sequential approach.

Two-phase guidance law for impact time control under physical constraints

An impact-time-control guidance law is required for the simultaneous attack of suicide attack unmanned aerial vehicles.Based on the nonlinear model,a two-phase guidance strategy is proposed.The impact time is derived in a simple analytical form of initial states and switching states,and it can be controlled by switching at an appropriate range.Firstly,a two-phase guidance law is designed to make the magnitude of the heading error decrease monotonically from its initial value to zero.And then,the feasible interval of the switching ranges and of the impact times under the acceleration constraint are given analytically in sequence.Furthermore,a general form of twophase guidance law is proposed,which allows the magnitude of the heading error to increase in the first phase,to improve the applicability of the methodology.Having the same structure as proportional navigation guidance with a time-varying gain,the proposed algorithms are simple and easy to implement.The corresponding feedback form is presented for realistic implementation.When a predefined impact time is taken within its permissible set,the constraints on the acceleration and fieldof-view will not be violated during the interception.Finally,simulations validate the effectiveness of the methodology in impact time control and salvo attack.

Impact Angle/Time Constraint Guidance Design Based on Fast Terminal Error Dynamics

Considering the problem that the optimal error dynamics can only converge at the terminal time,an impact angle/time constraint missile guidance law with finite-time convergence is designed in this paper,which is based on the pure proportional navigation(PPN)guidance law and the fast terminal error dynamics(FTED)approach.The missile guidance model and FTED equation are given first,and the dynamic equation of impact angle/time error based on PPN is also derived.Then,the guidance law is designed based on FTED,and the guidance error can converge to 0 in a finite time.Furthermore,considering the field of view constraint,the guidance law is improved by using the saturation function mapping method.Finally,a numerical simulation example is given to verify the effectiveness of the guidance law,which shows that the guidance law proposed in this paper can make the missile quickly adjust to the desired states in advance,and effectively relieve the overload saturation pressure of the actuator.