With the rapid development of mechanical equipment, the mechanical health monitoring field has entered the era of big data. However, the method of manual feature extraction has the disadvantages of low efficiency and ...With the rapid development of mechanical equipment, the mechanical health monitoring field has entered the era of big data. However, the method of manual feature extraction has the disadvantages of low efficiency and poor accuracy, when handling big data. In this study, the research object was the asynchronous motor in the drivetrain diagnostics simulator system. The vibration signals of different fault motors were collected. The raw signal was pretreated using short time Fourier transform (STFT) to obtain the corresponding time-frequency map. Then, the feature of the time-frequency map was adap- tively extracted by using a convolutional neural network (CNN). The effects of the pretreatment method, and the hyper parameters of network diagnostic accuracy, were investigated experimentally. The experimental results showed that the influence of the preprocessing method is small, and that the batch-size is the main factor affecting accuracy and training efficiency. By investigating feature visualization, it was shown that, in the case of big data, the extracted CNN features can represent complex mapping relationships between signal and health status, and can also overcome the prior knowledge and engineering experience requirement for feature extraction, which is used by tra- ditional diagnosis methods. This paper proposes a new method, based on STFT and CNN, which can complete motor fault diagnosis tasks more intelligently and accurately.展开更多
The application of ultrasound techniques to monitor the condition of structures is becoming more prominent because these techniques can detect the early symptoms of defects such as cracks and other defects.The early d...The application of ultrasound techniques to monitor the condition of structures is becoming more prominent because these techniques can detect the early symptoms of defects such as cracks and other defects.The early detection of defects is of vital importance to avoid major failures with catastrophic consequences.An assessment of an ultrasound technique was used to investigate fatigue damage behaviour.Fatigue tests were performed according to the ASTM E466-96 standard with the attachment of an ultrasound sensor to the test specimen.AISI 1045 carbon steel was used due to its wide application in the automotive industry.A fatigue test was performed under constant loading stress at a sampling frequency of 8 Hz.Two sets of data acquisition systems were used to collect the fatigue strain signals and ultrasound signals.All of the signals were edited and analysed using a signal processing approach.Two methods were used to evaluate the signals,the integrated Kurtosis-based algorithm for z-filter technique(I-kaz) and the short-time Fourier transform(STFT).The fatigue damage behaviour was observed from the initial stage until the last stage of the fatigue test.The results of the I-kaz coefficient and the STFT spectrum were used to explain and describe the behaviour of the fatigue damage.I-kaz coefficients were ranged from 60 to 61 for strain signals and ranged from 5 to 76 for ultrasound signals.I-kaz values tend to be high at failure point due to high amplitude of respective signals.STFT spectrogram displays the colour intensity which represents the damage severity of the strain signals.I-kaz technique is found very useful and capable in assessing both stationary and non-stationary signals while STFT technique is suitable only for non-stationary signals by displaying its spectrogram.展开更多
In this work, power efficient butterfly unit based FFT architecture is presented. The butterfly unit is designed using floating-point fused arithmetic units. The fused arithmetic units include two-term dot product uni...In this work, power efficient butterfly unit based FFT architecture is presented. The butterfly unit is designed using floating-point fused arithmetic units. The fused arithmetic units include two-term dot product unit and add-subtract unit. In these arithmetic units, operations are performed over complex data values. A modified fused floating-point two-term dot product and an enhanced model for the Radix-4 FFT butterfly unit are proposed. The modified fused two-term dot product is designed using Radix-16 booth multiplier. Radix-16 booth multiplier will reduce the switching activities compared to Radix-8 booth multiplier in existing system and also will reduce the area required. The proposed architecture is implemented efficiently for Radix-4 decimation in time(DIT) FFT butterfly with the two floating-point fused arithmetic units. The proposed enhanced architecture is synthesized, implemented, placed and routed on a FPGA device using Xilinx ISE tool. It is observed that the Radix-4 DIT fused floating-point FFT butterfly requires 50.17% less space and 12.16% reduced power compared to the existing methods and the proposed enhanced model requires 49.82% less space on the FPGA device compared to the proposed design. Also, reduced power consumption is addressed by utilizing the reusability technique, which results in 11.42% of power reduction of the enhanced model compared to the proposed design.展开更多
AIM: To determine if brain-derived neurotrophic factor (BDNF) could offer protention to retinal ganglion cells following a superior colliculus (SC) lesion in mice using pattern electroretinogram (PERG) and opti...AIM: To determine if brain-derived neurotrophic factor (BDNF) could offer protention to retinal ganglion cells following a superior colliculus (SC) lesion in mice using pattern electroretinogram (PERG) and optical coherence tomography (OCT) as a measures of ganglion cell response and retinal health. METHODS: Seven C57BIJ6J mice with BDNF protection were tested with PERG and OCT before and after SC lesions, RESULTS: Compared with baseline PERG, the amplitude of PERG decreased 11.7% after SC lesions, but not significantly(P〉0.05). Through fast Fourier transform (FFT) analysis of the PERGs before and after SC lesions, it was found that dominant frequency of PERGs stayed unchanged, suggesting that the ganglion cells of the retina remained relatively healthy inspite of damage to the ends of the ganglion cell axons. Also, OCT showed no changes in retinal thickness after lesions. CONCLUSION: It was concluded that BDNF is essential component of normal retinal and helps retina keeping normal function. While retina lack of BDNF, ex vivo resource of BDNF provides protection to the sick retina. It implies that BDNF is a kind therapeutic neurotrophic factor to retina neurodegeneration diseases, such as glaucoma, age related macular degeneration.展开更多
In this paper, we present a method for constructing multivariate tight framelet packets associated with an arbitrary dilation matrix using unitary extension principles. We also prove how to construct various tight fra...In this paper, we present a method for constructing multivariate tight framelet packets associated with an arbitrary dilation matrix using unitary extension principles. We also prove how to construct various tight frames for L2 (JRa) by replacing some mother framelets.展开更多
Since its inception in the 1970s,multi-dimensional magnetic resonance(MR)has emerged as a powerful tool for non-invasive investigations of structures and molecular interactions.MR spectroscopy beyond one dimension all...Since its inception in the 1970s,multi-dimensional magnetic resonance(MR)has emerged as a powerful tool for non-invasive investigations of structures and molecular interactions.MR spectroscopy beyond one dimension allows the study of the correlation,exchange processes,and separation of overlapping spectral information.The multi-dimensional concept has been re-implemented over the last two decades to explore molecular motion and spin dynamics in porous media.Apart from Fourier transform,methods have been developed for processing the multi-dimensional time-domain data,identifying the fluid components,and estimating pore surface permeability via joint relaxation and diffusion spectra.Through the resolution of spectroscopic signals with spatial encoding gradients,multi-dimensional MR imaging has been widely used to investigate the microscopic environment of living tissues and distinguish diseases.Signals in each voxel are usually expressed as multi-exponential decay,representing microstructures or environments along multiple pore scales.The separation of contributions from different environments is a common ill-posed problem,which can be resolved numerically.Moreover,the inversion methods and experimental parameters determine the resolution of multi-dimensional spectra.This paper reviews the algorithms that have been proposed to process multidimensional MR datasets in different scenarios.Detailed information at the microscopic level,such as tissue components,fluid types and food structures in multi-disciplinary sciences,could be revealed through multi-dimensional MR.展开更多
A semi-analytical method based on space harmonics to investigate the vibration of and sound radiation from an infinite, fluid-loaded plate is presented. The plate is reinforced with two sets of orthogonally and equall...A semi-analytical method based on space harmonics to investigate the vibration of and sound radiation from an infinite, fluid-loaded plate is presented. The plate is reinforced with two sets of orthogonally and equally spaced beam stiffeners, which are assumed to be line forces. The response of the stiffened plate to a convected harmonic pressure in the wave-number space is obtained by adopting the Green's function and Fourier transform methods. Using the boundary conditions and space harmonic method, we establish the relationship between the stiffener forces and the vibration displacement of the plate. In this paper, the stiffener forces are expressed in terms of harmonic amplitudes of the plate displacement, which are calculated by using a numerical reduction technique. Finally, the Fourier inverse transform is employed to find expressions of the vibration and sound radiation in physical space. Agreements with existing results prove the validity of this approach and more numerical results are presented to show that this method converges rapidly.展开更多
We prove the boundedness of fractional integral with a rough kernel on Triebel-Lizorkin spaces, where the rough kernel belongs to the block space and does not need to satisfy any moment conditions on the unit sphere.
In this article, we study the convex bodies associated with Lp-projections in the Brunn-Minkowski-Firey theory, and apply the Fourier analytic methods to prove the linear stability in the Shephard problem for Lp-proje...In this article, we study the convex bodies associated with Lp-projections in the Brunn-Minkowski-Firey theory, and apply the Fourier analytic methods to prove the linear stability in the Shephard problem for Lp-projections of convex bodies.展开更多
In this article, we extend the well known Wendel's theorem to the context of vector-valued L1-spaces on hypergroups. In this regard, various cases have been studied.
Compared to small molecule process analytical technology (PAT) applications, biotechnology product PAT applications have certain unique challenges and opportunities. Understanding process dynamics of bioreactor cell...Compared to small molecule process analytical technology (PAT) applications, biotechnology product PAT applications have certain unique challenges and opportunities. Understanding process dynamics of bioreactor cell culture process is essential to establish an appropriate process control strategy for biotechnology product PAT applications. Inline spectroscopic techniques for real time monitoring of bioreactor cell culture process have the distinct potential to develop PAT approaches in manufac- turing biotechnology drug products. However, the use of inline Fourier transform infrared (FTIR) spectroscopic techniques for bioreactor cell culture process monitoring has not been reported. In this work, real time inline FTIR Spectroscopy was applied to a lab scale bioreactor mAb IgG3 cell culture fluid biomolecular dynamic model. The technical feasibility of using FTIR Spectroscopy for real time tracking and monitoring four key cell culture metabolites (including glucose, glutamine, lactate, and ammonia) and protein yield at increasing levels of complexity (simple binary system, fully formulated media, actual bioreactor cell culture process) was evaluated via a stepwise approach. The FTIR fingerprints of the key metabolites were identified. The multivariate partial least squares (PLS) calibration models were established to correlate the process FTIR spectra with the concentrations of key metabolites and protein yield of in-process samples, either individually for each metabolite and protein or globally for all four metabolites simultaneously. Applying the 2'ld derivative pre-processing algorithm to the FTIR spectra helps to reduce the number of PLS latent variables needed significantly and thus simplify the interpretation of the PLS models. The validated PLS models show promise in predicting the concentration profiles of glucose, glutamine, lactate, and ammonia and protein yield over the course of the bioreactor cell culture process. Therefore, this work demonstrated the technical feasibility of real time monitoring of the bioreactor cell culture process via FTIR spectroscopy. Its implications for enabling cell culture PAT were discussed.展开更多
基金Supported by National Natural Science Foundation of China(Grant No.51405241,51505234,51575283)
文摘With the rapid development of mechanical equipment, the mechanical health monitoring field has entered the era of big data. However, the method of manual feature extraction has the disadvantages of low efficiency and poor accuracy, when handling big data. In this study, the research object was the asynchronous motor in the drivetrain diagnostics simulator system. The vibration signals of different fault motors were collected. The raw signal was pretreated using short time Fourier transform (STFT) to obtain the corresponding time-frequency map. Then, the feature of the time-frequency map was adap- tively extracted by using a convolutional neural network (CNN). The effects of the pretreatment method, and the hyper parameters of network diagnostic accuracy, were investigated experimentally. The experimental results showed that the influence of the preprocessing method is small, and that the batch-size is the main factor affecting accuracy and training efficiency. By investigating feature visualization, it was shown that, in the case of big data, the extracted CNN features can represent complex mapping relationships between signal and health status, and can also overcome the prior knowledge and engineering experience requirement for feature extraction, which is used by tra- ditional diagnosis methods. This paper proposes a new method, based on STFT and CNN, which can complete motor fault diagnosis tasks more intelligently and accurately.
基金Projects(UKM-KK-03-FRGS0118-2010,UKM-OUP-NBT-28-135/2011)supported by FRGS Universiti Kebangsaan Malaysia,Malaysia
文摘The application of ultrasound techniques to monitor the condition of structures is becoming more prominent because these techniques can detect the early symptoms of defects such as cracks and other defects.The early detection of defects is of vital importance to avoid major failures with catastrophic consequences.An assessment of an ultrasound technique was used to investigate fatigue damage behaviour.Fatigue tests were performed according to the ASTM E466-96 standard with the attachment of an ultrasound sensor to the test specimen.AISI 1045 carbon steel was used due to its wide application in the automotive industry.A fatigue test was performed under constant loading stress at a sampling frequency of 8 Hz.Two sets of data acquisition systems were used to collect the fatigue strain signals and ultrasound signals.All of the signals were edited and analysed using a signal processing approach.Two methods were used to evaluate the signals,the integrated Kurtosis-based algorithm for z-filter technique(I-kaz) and the short-time Fourier transform(STFT).The fatigue damage behaviour was observed from the initial stage until the last stage of the fatigue test.The results of the I-kaz coefficient and the STFT spectrum were used to explain and describe the behaviour of the fatigue damage.I-kaz coefficients were ranged from 60 to 61 for strain signals and ranged from 5 to 76 for ultrasound signals.I-kaz values tend to be high at failure point due to high amplitude of respective signals.STFT spectrogram displays the colour intensity which represents the damage severity of the strain signals.I-kaz technique is found very useful and capable in assessing both stationary and non-stationary signals while STFT technique is suitable only for non-stationary signals by displaying its spectrogram.
文摘In this work, power efficient butterfly unit based FFT architecture is presented. The butterfly unit is designed using floating-point fused arithmetic units. The fused arithmetic units include two-term dot product unit and add-subtract unit. In these arithmetic units, operations are performed over complex data values. A modified fused floating-point two-term dot product and an enhanced model for the Radix-4 FFT butterfly unit are proposed. The modified fused two-term dot product is designed using Radix-16 booth multiplier. Radix-16 booth multiplier will reduce the switching activities compared to Radix-8 booth multiplier in existing system and also will reduce the area required. The proposed architecture is implemented efficiently for Radix-4 decimation in time(DIT) FFT butterfly with the two floating-point fused arithmetic units. The proposed enhanced architecture is synthesized, implemented, placed and routed on a FPGA device using Xilinx ISE tool. It is observed that the Radix-4 DIT fused floating-point FFT butterfly requires 50.17% less space and 12.16% reduced power compared to the existing methods and the proposed enhanced model requires 49.82% less space on the FPGA device compared to the proposed design. Also, reduced power consumption is addressed by utilizing the reusability technique, which results in 11.42% of power reduction of the enhanced model compared to the proposed design.
文摘AIM: To determine if brain-derived neurotrophic factor (BDNF) could offer protention to retinal ganglion cells following a superior colliculus (SC) lesion in mice using pattern electroretinogram (PERG) and optical coherence tomography (OCT) as a measures of ganglion cell response and retinal health. METHODS: Seven C57BIJ6J mice with BDNF protection were tested with PERG and OCT before and after SC lesions, RESULTS: Compared with baseline PERG, the amplitude of PERG decreased 11.7% after SC lesions, but not significantly(P〉0.05). Through fast Fourier transform (FFT) analysis of the PERGs before and after SC lesions, it was found that dominant frequency of PERGs stayed unchanged, suggesting that the ganglion cells of the retina remained relatively healthy inspite of damage to the ends of the ganglion cell axons. Also, OCT showed no changes in retinal thickness after lesions. CONCLUSION: It was concluded that BDNF is essential component of normal retinal and helps retina keeping normal function. While retina lack of BDNF, ex vivo resource of BDNF provides protection to the sick retina. It implies that BDNF is a kind therapeutic neurotrophic factor to retina neurodegeneration diseases, such as glaucoma, age related macular degeneration.
文摘In this paper, we present a method for constructing multivariate tight framelet packets associated with an arbitrary dilation matrix using unitary extension principles. We also prove how to construct various tight frames for L2 (JRa) by replacing some mother framelets.
基金supported by the National Natural Science Foundation of China(No.61901465,82222032,82172050).
文摘Since its inception in the 1970s,multi-dimensional magnetic resonance(MR)has emerged as a powerful tool for non-invasive investigations of structures and molecular interactions.MR spectroscopy beyond one dimension allows the study of the correlation,exchange processes,and separation of overlapping spectral information.The multi-dimensional concept has been re-implemented over the last two decades to explore molecular motion and spin dynamics in porous media.Apart from Fourier transform,methods have been developed for processing the multi-dimensional time-domain data,identifying the fluid components,and estimating pore surface permeability via joint relaxation and diffusion spectra.Through the resolution of spectroscopic signals with spatial encoding gradients,multi-dimensional MR imaging has been widely used to investigate the microscopic environment of living tissues and distinguish diseases.Signals in each voxel are usually expressed as multi-exponential decay,representing microstructures or environments along multiple pore scales.The separation of contributions from different environments is a common ill-posed problem,which can be resolved numerically.Moreover,the inversion methods and experimental parameters determine the resolution of multi-dimensional spectra.This paper reviews the algorithms that have been proposed to process multidimensional MR datasets in different scenarios.Detailed information at the microscopic level,such as tissue components,fluid types and food structures in multi-disciplinary sciences,could be revealed through multi-dimensional MR.
基金Project supported by the National Natural Science Foundation of China (Nos. 05475150,50875030,10872039 and 90816025)
文摘A semi-analytical method based on space harmonics to investigate the vibration of and sound radiation from an infinite, fluid-loaded plate is presented. The plate is reinforced with two sets of orthogonally and equally spaced beam stiffeners, which are assumed to be line forces. The response of the stiffened plate to a convected harmonic pressure in the wave-number space is obtained by adopting the Green's function and Fourier transform methods. Using the boundary conditions and space harmonic method, we establish the relationship between the stiffener forces and the vibration displacement of the plate. In this paper, the stiffener forces are expressed in terms of harmonic amplitudes of the plate displacement, which are calculated by using a numerical reduction technique. Finally, the Fourier inverse transform is employed to find expressions of the vibration and sound radiation in physical space. Agreements with existing results prove the validity of this approach and more numerical results are presented to show that this method converges rapidly.
基金This work was supported in part by the National Natural Science Foundation of China (Grant Nos. 11561057, 11471309, 11271175) and the Natural Science Foundation of Jiangxi Province (No 20151BAB211002).
文摘We prove the boundedness of fractional integral with a rough kernel on Triebel-Lizorkin spaces, where the rough kernel belongs to the block space and does not need to satisfy any moment conditions on the unit sphere.
基金Supported by the National Natural Science Foundation of China(11161019)
文摘In this article, we study the convex bodies associated with Lp-projections in the Brunn-Minkowski-Firey theory, and apply the Fourier analytic methods to prove the linear stability in the Shephard problem for Lp-projections of convex bodies.
基金supported by senior research fellowship of CSIR,India
文摘In this article, we extend the well known Wendel's theorem to the context of vector-valued L1-spaces on hypergroups. In this regard, various cases have been studied.
文摘Compared to small molecule process analytical technology (PAT) applications, biotechnology product PAT applications have certain unique challenges and opportunities. Understanding process dynamics of bioreactor cell culture process is essential to establish an appropriate process control strategy for biotechnology product PAT applications. Inline spectroscopic techniques for real time monitoring of bioreactor cell culture process have the distinct potential to develop PAT approaches in manufac- turing biotechnology drug products. However, the use of inline Fourier transform infrared (FTIR) spectroscopic techniques for bioreactor cell culture process monitoring has not been reported. In this work, real time inline FTIR Spectroscopy was applied to a lab scale bioreactor mAb IgG3 cell culture fluid biomolecular dynamic model. The technical feasibility of using FTIR Spectroscopy for real time tracking and monitoring four key cell culture metabolites (including glucose, glutamine, lactate, and ammonia) and protein yield at increasing levels of complexity (simple binary system, fully formulated media, actual bioreactor cell culture process) was evaluated via a stepwise approach. The FTIR fingerprints of the key metabolites were identified. The multivariate partial least squares (PLS) calibration models were established to correlate the process FTIR spectra with the concentrations of key metabolites and protein yield of in-process samples, either individually for each metabolite and protein or globally for all four metabolites simultaneously. Applying the 2'ld derivative pre-processing algorithm to the FTIR spectra helps to reduce the number of PLS latent variables needed significantly and thus simplify the interpretation of the PLS models. The validated PLS models show promise in predicting the concentration profiles of glucose, glutamine, lactate, and ammonia and protein yield over the course of the bioreactor cell culture process. Therefore, this work demonstrated the technical feasibility of real time monitoring of the bioreactor cell culture process via FTIR spectroscopy. Its implications for enabling cell culture PAT were discussed.