Objective To explore the safety and efficacy of frameless stereotactic brain biopsy.Methods Diagnostic accuracy was calculated by comparing biopsy diagnosis with definitive pathology in 62 patients who underwent frame...Objective To explore the safety and efficacy of frameless stereotactic brain biopsy.Methods Diagnostic accuracy was calculated by comparing biopsy diagnosis with definitive pathology in 62 patients who underwent frameless stereotactic brain biopsy between January 2008 and December 2010 in Xiamen University Southeast Hospital.Preoperative characteristics and histological diagnosis were reviewed and then information was analysed to identify factors associated with the biopsy not yielding a diagnosis and complications.Results Diagnostic yield was 93.5%.No differences were found between pathological diagnosis and frozen pathological diagnosis.The most common lesions were astrocytic lesions,included 16 cases of low-grade glioma and 12 cases of malignant glioma.Remote hemorrhage,metastasis,and lymphoma were following in incidence.Multiple brain lesions were found in 17 cases (27.4%).Eleven cases were frontal lesions (17.7%),8 were frontotemporal (12.9%),6 were frontoparietal (9.7%),and 5 each were temporal,parietal,and parietotemporal lesions (8.1%).Postoperative complications occurred in 21.0% of the patients after biopsies,including 10 haemorrhages (16.1%) and 3 temporary neurological deficits (1 epilepsy,1 headache,and 1 partial hemiparesis).No patient required operation for hematoma evacuation.Conclusion Frameless stereotactic biopsy is an effective and safe technique for histologic diagnosis of brain lesions,particularly for multifocal and frontal lesions.展开更多
The key technologies involved in the evolution of the Cloud-based Radio Access Network(C-RAN) are discussed in this paper. Taking the Frameless Network Architecture(FNA) as a starting point, a cell-lessbased network t...The key technologies involved in the evolution of the Cloud-based Radio Access Network(C-RAN) are discussed in this paper. Taking the Frameless Network Architecture(FNA) as a starting point, a cell-lessbased network topology for a multi-tier Heterogeneous Network(Het Net) and ultra-dense network is proposed. The FNA network topology modeling is researched with centralized processing and distributed antenna deployments. The Antenna Element(AE) is released as a new dimensional radio resource that is included in the centralized Radio Resource Management(RRM) processes. This contributes to the on-demand user-centric serving-set associations with cell-edge effect elimination. The Control Plane(CP) and User Plane(UP) separation and adaptation are introduced for energy efficiency improvements. The centralized RRM and different optimization goals are discussed for fully exploring the merits from the centralized computing of C-RAN. Considering the complexity, near-optimal approaches for specific users' Quality-of-Service(Qo S) requirements are addressed. Finally, based on the research highlighted above, the way forward of C-RAN evolution is discussed.展开更多
文摘Objective To explore the safety and efficacy of frameless stereotactic brain biopsy.Methods Diagnostic accuracy was calculated by comparing biopsy diagnosis with definitive pathology in 62 patients who underwent frameless stereotactic brain biopsy between January 2008 and December 2010 in Xiamen University Southeast Hospital.Preoperative characteristics and histological diagnosis were reviewed and then information was analysed to identify factors associated with the biopsy not yielding a diagnosis and complications.Results Diagnostic yield was 93.5%.No differences were found between pathological diagnosis and frozen pathological diagnosis.The most common lesions were astrocytic lesions,included 16 cases of low-grade glioma and 12 cases of malignant glioma.Remote hemorrhage,metastasis,and lymphoma were following in incidence.Multiple brain lesions were found in 17 cases (27.4%).Eleven cases were frontal lesions (17.7%),8 were frontotemporal (12.9%),6 were frontoparietal (9.7%),and 5 each were temporal,parietal,and parietotemporal lesions (8.1%).Postoperative complications occurred in 21.0% of the patients after biopsies,including 10 haemorrhages (16.1%) and 3 temporary neurological deficits (1 epilepsy,1 headache,and 1 partial hemiparesis).No patient required operation for hematoma evacuation.Conclusion Frameless stereotactic biopsy is an effective and safe technique for histologic diagnosis of brain lesions,particularly for multifocal and frontal lesions.
基金supported by the National High Technology Research and Development Program of China No.2014AA01A701Nature and Science Foundation of China under Grants No.61471068,61421061+2 种基金Beijing Nova Programme No.Z131101000413030International Collaboration Project No.2015DFT10160National Major Project No.2016ZX03001009-003
文摘The key technologies involved in the evolution of the Cloud-based Radio Access Network(C-RAN) are discussed in this paper. Taking the Frameless Network Architecture(FNA) as a starting point, a cell-lessbased network topology for a multi-tier Heterogeneous Network(Het Net) and ultra-dense network is proposed. The FNA network topology modeling is researched with centralized processing and distributed antenna deployments. The Antenna Element(AE) is released as a new dimensional radio resource that is included in the centralized Radio Resource Management(RRM) processes. This contributes to the on-demand user-centric serving-set associations with cell-edge effect elimination. The Control Plane(CP) and User Plane(UP) separation and adaptation are introduced for energy efficiency improvements. The centralized RRM and different optimization goals are discussed for fully exploring the merits from the centralized computing of C-RAN. Considering the complexity, near-optimal approaches for specific users' Quality-of-Service(Qo S) requirements are addressed. Finally, based on the research highlighted above, the way forward of C-RAN evolution is discussed.