Graphical representation of hierarchical clustering results is of final importance in hierarchical cluster analysis of data. Unfortunately, almost all mathematical or statistical software may have a weak capability of...Graphical representation of hierarchical clustering results is of final importance in hierarchical cluster analysis of data. Unfortunately, almost all mathematical or statistical software may have a weak capability of showcasing such clustering results. Particularly, most of clustering results or trees drawn cannot be represented in a dendrogram with a resizable, rescalable and free-style fashion. With the “dynamic” drawing instead of “static” one, this research works around these weak functionalities that restrict visualization of clustering results in an arbitrary manner. It introduces an algorithmic solution to these functionalities, which adopts seamless pixel rearrangements to be able to resize and rescale dendrograms or tree diagrams. The results showed that the algorithm developed makes clustering outcome representation a really free visualization of hierarchical clustering and bioinformatics analysis. Especially, it possesses features of selectively visualizing and/or saving results in a specific size, scale and style (different views).展开更多
The Story of a Country House is one of the Swedish novelist Selma Lagerlöf’s short stories collected in her work From a Swedish Homestead.One of the crucial features in the story’s narrative is its telling of c...The Story of a Country House is one of the Swedish novelist Selma Lagerlöf’s short stories collected in her work From a Swedish Homestead.One of the crucial features in the story’s narrative is its telling of certain events and immediate retelling of part of that events by adopting another perspective,resulting in the overlapping of the narration of events that occur either in parallel with each other in the same time period in the story or in sequential time periods that happen to have significance on one another,thus the zigzag narration.We can see that the zigzag rendering of narration that does not follow the linear time order not only highlights the importance of the time period overlapped,but also leaves room for the introduction of different perspectives of various characters,if the introduction of a different perspective and voice is not the only purpose of shifting back the narrative time.We readers are thus granted access to more than one individual’s mindset to come to terms with the experiences partially shared by these characters to form a fuller picture of the whole situation.展开更多
<div style="text-align:justify;"> <span style="font-family:Verdana;"><strong>Background:</strong> The <sup>99m</sup>TcO<sub>4</sub><sup style=&quo...<div style="text-align:justify;"> <span style="font-family:Verdana;"><strong>Background:</strong> The <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy is commonly used for hyperthyroidism diagnosis. Uptake value of <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> on thyroid scintigraphy is an indicator of hyperthyroidism activity. Although, the correlation between free T3 value and free T4 value is not necessary clear in primary hyperthyroidism. <strong>Introduction: </strong>This study investigated the correlation between results of blood test and uptake of <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> on thyroid scintigraphy in primary hyperthyroidism. <strong>Methodlogy: </strong>In this retrspective study, uptake was calculated in patients diagnosed with primary hyperthyroidism (Graves’ disease/Basedow’s disease) based on clinical findings, blood tests, thyroid ultrasound, and <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy (uptake ≥3%) at St. Marianna University School of Medicine Hospital between 1 January 2010 and 31 December 2019. This uptake of <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> was compared with results of blood tests. <strong>Results:</strong> Fifty-four consecutively arriving patients at the hospital (12 men, 42 women;mean age 43.0 ± 14.0 years) were selected. Free T3 (n = 54) was 14.6 ± 6.8 pg/mL, free T4 (n = 53) was 5.0 ± 2.3 ng/mL, and uptake on thyroid scintigraphy was 10.0% ± 7.1%. The correlation coefficients were 0.60 (p < 0.01) between free T4 (all case), 0.39 (p < 0.01) between free T4 (under 7 ng/mL), 0.12 (p = 0.70) between free T4 (above 7 ng/mL) and <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy uptake. <strong>Conclusion:</strong> In primary hyperthyroidism (Graves’ disease), there is a correlation between free T4 value and <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy uptake, but there is no correlation in patients with high free T4 level.</span> </div>展开更多
目的探讨应用Free-style概念设计及切取小腿穿支螺旋桨皮瓣的可靠性及临床效果。方法2013年1月至2015年10月,对21例小腿或足踝部皮肤软组织缺损的患者,应用小腿Free-style穿支螺旋桨皮瓣进行修复。以多普勒超声确定距离创面最近的穿...目的探讨应用Free-style概念设计及切取小腿穿支螺旋桨皮瓣的可靠性及临床效果。方法2013年1月至2015年10月,对21例小腿或足踝部皮肤软组织缺损的患者,应用小腿Free-style穿支螺旋桨皮瓣进行修复。以多普勒超声确定距离创面最近的穿支,其中腓动脉穿支5例,胫后动脉穿支8例,胫前动脉穿支4例,腓肠内侧动脉穿支2例,未知名血管穿支2例,术中沿皮瓣一侧缘切开,确认穿支位置后,以此为皮瓣旋转点,设计螺旋桨皮瓣,大桨覆盖受区创面,小桨覆盖供区创面。术中发现动脉穿支与多普勒定位基本符合的12例,与多普勒定位相差小于2.0 cm的8例,明显不符合的1例,源血管不确切的2例,术中均及时修改设计。皮瓣切取面积7.0 cm × 4.0 cm-16.0 cm × 7.0 cm,11例患者供区直接缝合,10例患者供区取皮游离植皮。结果18例皮瓣顺利成活,3例皮瓣术后出现静脉危象,经蒂部拆线、换药等处理后成活。术后随访6-12个月,平均9个月,皮瓣色泽、质地优良,皮瓣蒂部平整,供、受区外形满意。结论应用Free-style概念设计及切取小腿穿支螺旋桨皮瓣,无需考虑穿支血管的来源,增加了手术灵活性,能有效提高皮瓣切取成功率,且操作简单,不损伤小腿主要血管,适合基层医院开展,是修复小腿及足踝部皮肤软组织缺损理想的方法。展开更多
文摘Graphical representation of hierarchical clustering results is of final importance in hierarchical cluster analysis of data. Unfortunately, almost all mathematical or statistical software may have a weak capability of showcasing such clustering results. Particularly, most of clustering results or trees drawn cannot be represented in a dendrogram with a resizable, rescalable and free-style fashion. With the “dynamic” drawing instead of “static” one, this research works around these weak functionalities that restrict visualization of clustering results in an arbitrary manner. It introduces an algorithmic solution to these functionalities, which adopts seamless pixel rearrangements to be able to resize and rescale dendrograms or tree diagrams. The results showed that the algorithm developed makes clustering outcome representation a really free visualization of hierarchical clustering and bioinformatics analysis. Especially, it possesses features of selectively visualizing and/or saving results in a specific size, scale and style (different views).
文摘The Story of a Country House is one of the Swedish novelist Selma Lagerlöf’s short stories collected in her work From a Swedish Homestead.One of the crucial features in the story’s narrative is its telling of certain events and immediate retelling of part of that events by adopting another perspective,resulting in the overlapping of the narration of events that occur either in parallel with each other in the same time period in the story or in sequential time periods that happen to have significance on one another,thus the zigzag narration.We can see that the zigzag rendering of narration that does not follow the linear time order not only highlights the importance of the time period overlapped,but also leaves room for the introduction of different perspectives of various characters,if the introduction of a different perspective and voice is not the only purpose of shifting back the narrative time.We readers are thus granted access to more than one individual’s mindset to come to terms with the experiences partially shared by these characters to form a fuller picture of the whole situation.
文摘<div style="text-align:justify;"> <span style="font-family:Verdana;"><strong>Background:</strong> The <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy is commonly used for hyperthyroidism diagnosis. Uptake value of <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> on thyroid scintigraphy is an indicator of hyperthyroidism activity. Although, the correlation between free T3 value and free T4 value is not necessary clear in primary hyperthyroidism. <strong>Introduction: </strong>This study investigated the correlation between results of blood test and uptake of <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> on thyroid scintigraphy in primary hyperthyroidism. <strong>Methodlogy: </strong>In this retrspective study, uptake was calculated in patients diagnosed with primary hyperthyroidism (Graves’ disease/Basedow’s disease) based on clinical findings, blood tests, thyroid ultrasound, and <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy (uptake ≥3%) at St. Marianna University School of Medicine Hospital between 1 January 2010 and 31 December 2019. This uptake of <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> was compared with results of blood tests. <strong>Results:</strong> Fifty-four consecutively arriving patients at the hospital (12 men, 42 women;mean age 43.0 ± 14.0 years) were selected. Free T3 (n = 54) was 14.6 ± 6.8 pg/mL, free T4 (n = 53) was 5.0 ± 2.3 ng/mL, and uptake on thyroid scintigraphy was 10.0% ± 7.1%. The correlation coefficients were 0.60 (p < 0.01) between free T4 (all case), 0.39 (p < 0.01) between free T4 (under 7 ng/mL), 0.12 (p = 0.70) between free T4 (above 7 ng/mL) and <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy uptake. <strong>Conclusion:</strong> In primary hyperthyroidism (Graves’ disease), there is a correlation between free T4 value and <sup>99m</sup>TcO<sub>4</sub><sup style="margin-left:-7px;">-</sup> thyroid scintigraphy uptake, but there is no correlation in patients with high free T4 level.</span> </div>
文摘目的探讨应用Free-style概念设计及切取小腿穿支螺旋桨皮瓣的可靠性及临床效果。方法2013年1月至2015年10月,对21例小腿或足踝部皮肤软组织缺损的患者,应用小腿Free-style穿支螺旋桨皮瓣进行修复。以多普勒超声确定距离创面最近的穿支,其中腓动脉穿支5例,胫后动脉穿支8例,胫前动脉穿支4例,腓肠内侧动脉穿支2例,未知名血管穿支2例,术中沿皮瓣一侧缘切开,确认穿支位置后,以此为皮瓣旋转点,设计螺旋桨皮瓣,大桨覆盖受区创面,小桨覆盖供区创面。术中发现动脉穿支与多普勒定位基本符合的12例,与多普勒定位相差小于2.0 cm的8例,明显不符合的1例,源血管不确切的2例,术中均及时修改设计。皮瓣切取面积7.0 cm × 4.0 cm-16.0 cm × 7.0 cm,11例患者供区直接缝合,10例患者供区取皮游离植皮。结果18例皮瓣顺利成活,3例皮瓣术后出现静脉危象,经蒂部拆线、换药等处理后成活。术后随访6-12个月,平均9个月,皮瓣色泽、质地优良,皮瓣蒂部平整,供、受区外形满意。结论应用Free-style概念设计及切取小腿穿支螺旋桨皮瓣,无需考虑穿支血管的来源,增加了手术灵活性,能有效提高皮瓣切取成功率,且操作简单,不损伤小腿主要血管,适合基层医院开展,是修复小腿及足踝部皮肤软组织缺损理想的方法。