Regression Function Comparison for Paired Data

In this paper,the regression function comparison for paired data is studied.The proposed test statistic is based on the weighted integral of characteristic function marked by the difference of responses.There are several merits of the proposed statistic.For instance,it takes a simple V-statistic form.No bandwidth is needed.No moment conditions are required for covariates.It can be applied to covariates of any fixed dimension.The asymptotic results are also developed.It is proven that n times the proposed test statistic converges to a finite limit under the null hypothesis and the test is consistent against any fixed alternatives.Local alternative hypotheses which converge to the null hypothesis at the rate of n-1/2 are also detected.A suitable Bootstrap algorithm is also proposed for the implementation of the proposed test statistic.Simulation studies are carried out to illustrate the merits of the proposed method.A real data example is also used to illustrate the proposed testing procedures.

On stability of discontinuous systems via vector Lyapunov functions

This paper deals with the stability of systems with discontinuous righthand side （with solutions in Filippov＇s sense） via locally Lipschitz continuous and regular vector Lyapunov functions. A new type of “set-valued derivative” of vector Lyapunov functions is introduced, some generalized comparison principles on discontinuous systems are shown. Furthermore, Lyapunov stability theory is developed for a class of discontinuous systems based on locally Lipschitz continuous and regular vector Lyapunov functions.

Nutech functional score: A novel scoring system to assess spinal cord injury patients

AIM To develop a new scoring system, nutech functional scores(NFS) for assessing the patients with spinal cord injury(SCI).METHODS The conventional scale, American Spinal Injury Association's(ASIA) impairment scale is a measure which precisely describes the severity of the SCI.However, it has various limitations which lead to incomplete assessment of SCI patients.We have developed a 63 point scoring system, i.e., NFS for patients suffering with SCI.A list of symptoms either common or rare that were found to be associated with SCI was recorded for each patient.On the basis of these lists, we have developed NFS.RESULTS These lists served as a base to prepare NFS, a 63 point positional(each symptom is sub-graded and get points based on position) and directional(moves in direction BAD → GOOD) scoring system.For non-progressive diseases, 1, 2, 3, 4, 5 denote worst, bad, moderate, good and best(normal), respectively.NFS for SCI has been divided into different groups based on the affected part of the body being assessed, i.e., motor assessment(shoulders, elbow, wrist, fingers-grasp, fingers-release, hip, knee, ankle and toe), sensory assessment, autonomic assessment, bed sore assessment and general assessment.As probability based studies required a range of(-1, 1) or at least the range of(0, 1) to be useful for real world analysis, the grades were converted to respective numeric values.CONCLUSION NFS can be considered as a unique tool to assess the improvement in patients with SCI as it overcomes the limitations of ASIA impairment scale.

The Light of Human Nature——on the Function of Character Lena Grove in Light in August

This paper aims at explaining the importance and function of the character Lena Grove in William Faulkner’s famous novel Light in August. The meaning of the title is explored by making comparisons between Lena and other main characters.

失业保险制度的功能转型与变迁路径——基于美、德、日三国的比较研究

在社会保险体系之中,失业保险建立的时间通常相对较晚,且存在颇多争议。基于制度变迁理论建立分析框架,探究美国、德国、日本失业保险发展变迁的共性与差异的结果显示:美国失业保险体系长期保持较低的保障水平,注重发挥逆周期调节功能,具有很强的漂移特征;德国通过“哈茨改革”实现“二元化”制度层叠,划清国家责任与企业责任、个人责任的边界,增强失业保险运行的可持续性;日本“三事业”改革用雇佣保险替代失业保险,服务于促进终身就业的战略。以典型国家为参照,我国应继续扩大失业保险的覆盖面并合理调适失业保险制度目标;通过层叠制度设置为非正规就业群体提供“保基本”的失业救助;拓展失业保险的功能,将稳定就业与逆周期调节纳入制度目标,激活经济运行动能;建立失业保险储备基金与费率灵活调整机制,促进基金稳健运行。

Therapeutic effect of regulating autophagy in spinal cord injury: a network meta-analysis of direct and indirect comparisons

Objective:An increasing number of studies indicate that autophagy plays an important role in the pathogenesis of spinal cord injury,and that regulating autophagy can enhance recovery from spinal cord injury.However,the effect of regulating autophagy and whether autophagy is detrimental or beneficial after spinal cord injury remain unclear.Therefore,in this study we evaluated the effects of autophagy regulation on spinal cord injury in rats by direct and indirect comparison,in an effort to provide a basis for further research.Data source:Relevant literature published from inception to February 1,2018 were included by searching Wanfang,CNKI,Web of Science,MEDLINE(OvidSP),PubMed and Google Scholar in English and Chinese.The keywords included"autophagy","spinal cord injury",and"rat".Data selection:The literature included in vivo experimental studies on autophagy regulation in the treatment of spinal cord injury(including intervention pre-and post-spinal cord injury).Meta-analyses were conducted at different time points to compare the therapeutic effects of promoting or inhibiting autophagy,and subgroup analyses were also conducted.Outcome measure:Basso,Beattie,and Bresnahan scores.Results:Of the 622 studies,33 studies of median quality were included in the analyses.Basso,Beattie,and Bresnahan scores were higher at 1 day(MD=1.80,95%CI:0.81-2.79,P=0.0004),3 days(MD=0.92,95%CI:0.72-1.13,P<0.00001),1 week(MD=2.39,95%CI:1.85-2.92,P<0.00001),2 weeks(MD=3.26,95%CI:2.40-4.13,P<0.00001),3 weeks(MD=3.13,95%CI:2.51-3.75,P<0.00001)and 4 weeks(MD=3.18,95%CI:2.43-3.92,P<0.00001)after spinal cord injury with upregulation of autophagy compared with the control group(drug solvent control,such as saline group).Basso,Beattie,and Bresnahan scores were higher at 1 day(MD=6.48,95%CI:5.83-7.13,P<0.00001),2 weeks(MD=2.43,95%CI:0.79-4.07,P=0.004),3 weeks(MD=2.96,95%CI:0.09-5.84,P=0.04)and 4 weeks(MD=4.41,95%CI:1.08-7.75,P=0.01)after spinal cord injury with downregulation of autophagy compared with the control group.Indirect comparison of upregulation and downregulation of autophagy showed no differences in Basso,Beattie,and Bresnahan scores at 1 day(MD=-4.68,95%CI:-5.840 to-3.496,P=0.94644),3 days(MD=-0.28,95%CI:-2.231-1.671,P=0.99448),1 week(MD=1.83,95%CI:0.0076-3.584,P=0.94588),2 weeks(MD=0.81,95%CI:-0.850-2.470,P=0.93055),3 weeks(MD=0.17,95%Cl:-2.771-3.111,P=0.99546)or 4 weeks(MD=-1.23,95%Cl:-4.647-2.187,P=0.98264)compared with the control group.Conclusion:Regulation of autophagy improves neurological function,whether it is upregulated or downregulated.There was no difference between upregulation and downregulation of autophagy in the treatment of spinal cord injury.The variability in results among the studies may be associated with differences in research methods,the lack of clearly defined autophagy characteristics after spinal cord injury,and the limited autophagy monitoring techniques.Thus,methods should be standardized,and the dynamic regulation of autophagy should be examined in future studies.

半夏泻心汤治疗功能性消化不良的机制研究

目的 评估不同功能性消化不良(FD)造模方法的效果,并探讨半夏泻心汤对FD的治疗作用及潜在机制。方法 BALB/c小鼠随机分为空白组、碘乙酰胺组、洛哌丁胺组、夹尾组和食醋组。经过1周干预,观察各组小鼠状态并检测其胃肠动力、激素水平及病理变化,评估并确定一种较为理想的FD造模方法。造模后给予不同剂量半夏泻心汤进行干预,观察小鼠胃肠功能的改变,并通过免疫组化、ELISA、Western blot等实验方法研究相关蛋白表达情况。结果 对4种造模方法进行比较发现,碘乙酰胺组、洛哌丁胺组和食醋组小鼠与空白组相比体质量有所减轻;碘乙酰胺组和食醋组小鼠胃排空率及小肠推进率下降;夹尾组及食醋组小鼠血清中胃肠激素发生变化。最后评估碘乙酰胺法为最优的FD造模方法。给药结果显示半夏泻心汤对FD小鼠进食量及体质量无明显影响,中、高剂量可改善FD小鼠身体状态,提高其胃排空率与小肠推进率。免疫组织化学、ELISA、Western blot等实验结果证实,中、高剂量半夏泻心汤可显著降低FD小鼠十二指肠及血清内TNF-α及IL-6的表达水平。结论 碘乙酰胺法是一种更优的FD造模方法。半夏泻心汤可改善FD小鼠状态,提高胃肠动力,通过降低炎症因子分泌达到治疗FD的作用。

11份饲用甜高粱品种在凉山州的生产性能及营养价值评价

为筛选出适宜在凉山州中低海拔地区种植的饲用甜高粱品种,本研究采用随机区组设计,对11份甜高粱(Sorghum saccharatum Moench)的农艺性状、生产性能和营养成分相关指标进行测定,通过隶属函数法和Topsis(Technique for order preference by similarity to an ideal solution)法进行综合分析。参试品种中‘大力士’的鲜草和干物质产量最高,分别为80850.91 kg·hm^(-2)和22234.02 kg·hm^(-2),显著高于其他品种(P<0.05)。干鲜比最大的为‘丰甜’(0.38),茎叶比最小的为‘F10’(2.07)。‘BMR 3631’的粗蛋白(Crude protein,CP)含量和相对牧草质量(Relative forage quality,RFQ)显著高于其他品种(P<0.05),中性洗涤纤维(Neutral detergent fiber,NDF)和酸性洗涤纤维(Acid detergent fiber,ADF)含量均最低。相关性分析表明鲜草产量与株高呈显著正相关关系(P<0.05),CP含量与鲜干物质产量呈显著负相关关系(P<0.05),ADF和NDF含量与株高呈极显著正相关关系(P<0.01)。隶属函数与Topsis综合分析表明‘德胜’和‘大力士’两个品种具有较高的饲草产量和营养品质,适宜在当地种植。

建筑碳排放软件对比分析及计算研究

为更好地控制建筑碳排放量,建筑碳排放的测算与管理至关重要。基于此,对PKPM-CES建筑碳排放计算软件V3、东禾建筑碳排放软件、绿建斯维尔建筑碳排放CEEB 2023等3款建筑施工领域常用的碳排放软件进行了对比研究,分析其适用范围和计算过程,通过实际案例对其计算结果进行对比分析并总结各自的优缺点,以期为技术人员选择软件提供参考,并为新软件的开发提供建议。

河西走廊地区不同饲用高粱品种的生产性能与营养品质比较分析

试验旨在解决河西走廊干旱半干旱种植区畜牧业发展过程中存在的优质、高产饲草紧缺的问题。试验选取9个不同饲草高粱品种作为研究对象,通过测定分析其生育期、生产特性、草产量和营养品质等性状,开展品种比较试验,运用模糊数学隶属函数进行综合评价。结果显示:参试品种的物候期虽有差异,但均能够完成整个生育进程;克沃2号、超级糖王、辽甜1号的鲜草产量分别为125 803.10、118 317.04、102 914.09 kg/hm^(2),干草产量分别为43 817.22、45 350.92、30 565.49 kg/hm^(2),均显著高于其他品种(P<0.05);粗蛋白(CP)和粗脂肪(EE)含量最高的品种是BJ0906,依次为12.56%、2.96%,显著高于其他品种(P<0.05);水溶性碳水化合物(WSC)含量最高的品种是雅津4148,为40.60%,显著高于其他品种(P<0.05);中性洗涤纤维(NDF)、酸性洗涤纤维(ADF)含量最低的品种是BJ0906,依次为40.24%、27.34%,显著低于除超级糖王外的其他品种(P<0.05);相对饲用价值(RFV)和相对牧草品质(RFQ)最高的是BJ0906,最低的是大力士。平均隶属函数值较高的是BJ0906、超级糖王,综合生产性能表现最差的品种是大力士。研究表明,BJ0906和超级糖王适合在河西走廊干旱半干旱种植区大面积种植,在实际生产种植过程中可根据不同的用途选择合适的品种。

基于TestBed/TBrun的高效测试执行方法

在使用TestBed/TBrun工具执行软件单元测试用例过程中,存在长数组无法自动赋值和结果比对导致测试效率低的问题。针对该问题,提出了一种基于TestBed/TBrun的高效测试执行方法。通过在后台文件中建立可自动识别读取长数组的通用驱动函数和自动对比测试结果的比对函数,对软件单元中的长数组输入/输出变量进行自动赋值及结果比对。经测试验证,该方法降低了用例执行耗时,提高了测试执行效率。

基于双光频梳及受激布里渊散射的微波频率测量

提出了一种基于双光频梳和受激布里渊散射的高精度微波频率测量方法,利用两个双平行马赫-曾德尔调制器将待测微波信号和扫描信号调制在两路光频梳上,并分别作为信号光和泵浦光输入色散位移光纤中。利用双光频梳和不断频移的扫描信号,系统可同时实现波分复用和时分复用。同时,在双光频梳和受激布里渊散射的作用下,系统可发生一系列的受激布里渊散射,通过测量各信道输出的光功率实现待测微波频率的测量。为进一步提升测量精度,利用测量得到的光功率值构建幅度比较函数,从而实现频率测量误差修正。通过实验仿真验证了所提方法的有效性,测量误差为±2.5 MHz。

汉韩典型性话语标记语语用功能对比研究——以提请注意式话语标记语为例

某种语言形式从一般属性,经过语法化过程,在原本意义基础上增添了其程序上的意义,具有了话语标记语的功能。典型性话语标记语的语法化程度较高,与其原本意义相比,各话语标记语的程序意义占主导地位。因此所属不同语系的汉韩两语典型性话语标记语的表现形式差异显著。拟以提请注意式话语标记语为例,依据关联理论从语言认知学的角度对汉韩典型性话语标记语的语用功能进行跨语言对比分析,考察其相似性与差异性。弥补学界从大类型视角对话语标记语跨语言研究的不足,加深对典型性话语标记语的认知,以期对语言教学和习得研究有所裨益。

几类新型中值定理中值点的渐近性

研究几类新型中值定理中值点的渐近性,利用比较函数和引理,在一定条件下,建立了几类新型中值定理中值点更广泛的渐近估计式,所得结果推广和改进了有关文献中的相应结果。

基于价值工程的高速公路路线方案比选方法研究

为积极贯彻新时期“以功能为基点”的设计理念,提出一种基于价值工程的高速公路路线方案比选方法。首先通过对高速公路功能的系统性分析构建了路线方案功能评价指标体系,综合采用极值处理法、二元对比权重分析法、1~9标度法等计算各指标评分、指标权重及方案功能评分;然后利用国内相关统计数据和养护成本预测模型,计算出全寿命周期成本;最后引入价值工程理论计算出各方案的价值指数,通过比较价值指数的大小选取最优方案。将该方法应用于武汉至重庆高速公路汉川至天门段路线方案比选中,结果验证了该方法的科学性和实用性,可为高速公路路线方案决策提供理论依据。

利用隶属函数法综合评价4个华北型黄瓜品种

为了科学地筛选出适宜鲁南地区的早春黄瓜优良品种,提高早春黄瓜种植茬口产量,获得更高的经济效益,将4个华北型黄瓜杂交新品种(津早218、圣优93、圣夏108、冬灵48)进行春提早栽培,对其植物学特性、果实外观品质、商品性、品质、产量和抗病性等进行比较,并利用模糊隶属函数法对瓜条性状、产量,品质、抗病性进行综合评价。结果表明:圣优93采收天数较其他品种延长5~7 d;与其他试验品种相比,圣优93霜霉病病情指数最低,为15.38,并且产量显著高于其他参试品种,为213035.70 kg·hm^(-2);圣优93可溶性固形物含量方面与津早218没有显著差异,但均显著高于其他参试品种,其总糖量方面显著高于其他品种,极显著高于冬灵48;经模糊隶属函数法综合排名,圣优93总隶属函数值排名第1。综上所述,圣优93可作为该地区黄瓜品种栽培的首要选择,隶属函数法能够较客观地评价各品种表现,可辅助黄瓜新品种的综合评价。

石家庄市中华大街与北三环互通立交设计

石家庄市北三环市政化改造项目启动,石太高速公路、黄石高速公路在三环内的部分被命名为“北三环”,中华大街与北三环节点作为规划枢纽立交成为此次改造的关键节点。节点北侧紧邻西环铁路线,南侧紧邻高标准行洪通道及高层建筑,周边用地条件受限。结合建设条件,给出多个互通立交设计方案,通过交通功能、工程投资、水利防洪等方面的综合比选,确定立交总体设计方案。

补中益气汤加味联合吉西他滨在非肌层浸润性膀胱癌术后中的应用

目的 探讨补中益气汤加味联合吉西他滨在非肌层浸润性膀胱癌术后的应用价值。方法 选取2022年1月至2024年1月陕西省商洛市中心医院收治的102例非肌层浸润性膀胱癌患者为对象,按随机数字表法分为对照组和观察组,各51例。对照组术后予以吉西他滨治疗,观察组予以补中益气汤联合吉西他滨治疗。评估2组临床疗效、中医证候积分、免疫功能、治疗安全性。结果 观察组有效率高于对照组(P <0.05)。观察组中医证候评分均低于对照组(P <0.05)。治疗后,观察组CD4^(+)、CD3^(+)、CD4^(+)/CD8^(+)高于治疗前,CD8^(+)低于治疗前(P <0.05)。2组不良反应发生率差异无统计学意义(P> 0.05)。结论 补中益气汤加味联合吉西他滨在非肌层浸润性膀胱癌术后应用效果良好,可减轻患者主要中医证候,提高机体免疫功能,治疗安全性良好。

系统功能语言学视角下英汉语强调句式对比与转换探析

论述系统功能语言学理论概念和强调句式概念,而后通过举例说明英汉语强调句式在强调主语、谓语、宾语和状语等方面的不同具有一定的必要性。分析英汉语强调句式转换策略和不同侧重点,以系统功能语言学理论来构建强调语义模型,揭示强调句式的差异和转换逻辑,彰显强调句式在英汉语言交流中发挥的修辞作用,以提升不同文化背景下的人们对英汉语言的欣赏程度。