Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby c...Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby contributing to the advancement of camouflage evaluation.In this study,images with various camouflage effects were presented to observers to generate electroencephalography(EEG)signals,which were then used to construct a brain functional network.The topological parameters of the network were subsequently extracted and input into a machine learning model for training.The results indicate that most of the classifiers achieved accuracy rates exceeding 70%.Specifically,the Logistic algorithm achieved an accuracy of 81.67%.Therefore,it is possible to predict target camouflage effectiveness with high accuracy without the need to calculate discovery probability.The proposed method fully considers the aspects of human visual and cognitive processes,overcomes the subjectivity of human interpretation,and achieves stable and reliable accuracy.展开更多
Landslides are common natural hazards occurring in most parts of the world and have considerable adverse economic effects. Residual shear strength of clay is one of the most important factors in the determination of s...Landslides are common natural hazards occurring in most parts of the world and have considerable adverse economic effects. Residual shear strength of clay is one of the most important factors in the determination of stability of slopes or landslides. This effect is more pronounced in sensitive clays which show large changes in shear strength from peak to residual states. This study analyses the prediction of the residual strength of clay based on a new prediction model, functional networks(FN) using data available in the literature. The performance of FN was compared with support vector machine(SVM) and artificial neural network(ANN) based on statistical parameters like correlation coefficient(R), Nash–Sutcliff coefficient of efficiency(E), absolute average error(AAE), maximum average error(MAE) and root mean square error(RMSE). Based on R and E parameters, FN is found to be a better prediction tool than ANN for the given data. However, the R and E values for FN are less than SVM. A prediction equation is presented that can be used by practicing geotechnical engineers. A sensitivity analysis is carried out to ascertain the importance of various inputs in the prediction of the output.展开更多
The structure and function of brain networks have been altered in patients with end-stage renal disease(ESRD).Manifold regularization(MR)only considers the pairing relationship between two brain regions and cannot rep...The structure and function of brain networks have been altered in patients with end-stage renal disease(ESRD).Manifold regularization(MR)only considers the pairing relationship between two brain regions and cannot represent functional interactions or higher-order relationships between multiple brain regions.To solve this issue,we developed a method to construct a dynamic brain functional network(DBFN)based on dynamic hypergraph MR(DHMR)and applied it to the classification of ESRD associated with mild cognitive impairment(ESRDaMCI).The construction of DBFN with Pearson’s correlation(PC)was transformed into an optimization model.Node convolution and hyperedge convolution superposition were adopted to dynamically modify the hypergraph structure,and then got the dynamic hypergraph to form the manifold regular terms of the dynamic hypergraph.The DHMR and L_(1) norm regularization were introduced into the PC-based optimization model to obtain the final DHMR-based DBFN(DDBFN).Experiment results demonstrated the validity of the DDBFN method by comparing the classification results with several related brain functional network construction methods.Our work not only improves better classification performance but also reveals the discriminative regions of ESRDaMCI,providing a reference for clinical research and auxiliary diagnosis of concomitant cognitive impairments.展开更多
The purpose of the paper is to provide a way to model the brain functional network based on the complex networks with brain anatomical architecture. We introduce the brain structural and functional researches, and del...The purpose of the paper is to provide a way to model the brain functional network based on the complex networks with brain anatomical architecture. We introduce the brain structural and functional researches, and delineate the brain anatomical and functional networks based on complex networks, then we discuss the brain functional complex network models; at last we put forward the brain functional networks modeling process and the data processing with fMRI (functional magnetic resonance imaging) in detailed.展开更多
Functional networks(FNs)hold significant promise in understanding brain function.Independent component analysis(ICA)has been applied in estimating FNs from functional magnetic resonance imaging(fMRI).However,determini...Functional networks(FNs)hold significant promise in understanding brain function.Independent component analysis(ICA)has been applied in estimating FNs from functional magnetic resonance imaging(fMRI).However,determining an optimal model order for ICA remains challenging,leading to criticism about the reliability of FN estimation.Here,we propose a SMART(splitting-merging assisted reliable)ICA method that automatically extracts reliable FNs by clustering independent components(ICs)obtained from multi-model-order ICA using a simplified graph while providing linkages among FNs deduced from different-model orders.We extend SMART ICA to multi-subject fMRI analysis,validating its effectiveness using simulated and real fMRI data.Based on simulated data,the method accurately estimates both group-common and group-unique components and demonstrates robustness to parameters.Using two age-matched cohorts of resting fMRI data comprising 1,950 healthy subjects,the resulting reliable group-level FNs are greatly similar between the two cohorts,and interestingly the subject-specific FNs show progressive changes while age increases.Furthermore,both small-scale and large-scale brain FN templates are provided as benchmarks for future studies.Taken together,SMART ICA can automatically obtain reliable FNs in analyzing multi-subject fMRI data,while also providing linkages between different FNs.展开更多
Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network lev...Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery.展开更多
Currently,functional connectomes constructed from neuroimaging data have emerged as a powerful tool in identifying brain disorders.If one brain disease just manifests as some cognitive dysfunction,it means that the di...Currently,functional connectomes constructed from neuroimaging data have emerged as a powerful tool in identifying brain disorders.If one brain disease just manifests as some cognitive dysfunction,it means that the disease may affect some local connectivity in the brain functional network.That is,there are functional abnormalities in the sub-network.Therefore,it is crucial to accurately identify them in pathological diagnosis.To solve these problems,we proposed a sub-network extraction method based on graph regularization nonnegative matrix factorization(GNMF).The dynamic functional networks of normal subjects and early mild cognitive impairment(eMCI)subjects were vectorized and the functional connection vectors(FCV)were assembled to aggregation matrices.Then GNMF was applied to factorize the aggregation matrix to get the base matrix,in which the column vectors were restored to a common sub-network and a distinctive sub-network,and visualization and statistical analysis were conducted on the two sub-networks,respectively.Experimental results demonstrated that,compared with other matrix factorization methods,the proposed method can more obviously reflect the similarity between the common subnetwork of eMCI subjects and normal subjects,as well as the difference between the distinctive sub-network of eMCI subjects and normal subjects,Therefore,the high-dimensional features in brain functional networks can be best represented locally in the lowdimensional space,which provides a new idea for studying brain functional connectomes.展开更多
Functional brain networks (FBN) based on resting-state functional magnetic resonance imaging (rs-fMRI) have become an important tool for exploring underlying organization patterns in the brain, which can provide an ob...Functional brain networks (FBN) based on resting-state functional magnetic resonance imaging (rs-fMRI) have become an important tool for exploring underlying organization patterns in the brain, which can provide an objective basis for brain disorders such as autistic spectrum disorder (ASD). Due to its importance, researchers have proposed a number of FBN estimation methods. However, most existing methods only model a type of functional connection relationship between brain regions-of-interest (ROIs), such as partial correlation or full correlation, which is difficult to fully capture the subtle connections among ROIs since these connections are extremely complex. Motivated by the multi-view learning, in this study we propose a novel Consistent and Specific Multi-view FBNs Fusion (CSMF) approach. Concretely, we first construct multi-view FBNs (i.e., multiple types of FBNs modelling various relationships among ROIs), and then these FBNs are decomposed into a consistent representation matrix and their own specific matrices which capture their common and unique information, respectively. Lastly, to obtain a better brain representation, it is fusing the consistent and specific representation matrices in the latent representation spaces of FBNs, but not directly fusing the original FBNs. This potentially makes it more easily to find the comprehensively brain connections. The experimental results of ASD identification on the ABIDE datasets validate the effectiveness of our proposed method compared to several state-of-the-art methods. Our proposed CSMF method achieved 72.8% and 76.67% classification performance on the ABIDE dataset.展开更多
With the advancements of software defined network(SDN)and network function virtualization(NFV),service function chain(SFC)placement becomes a crucial enabler for flexible resource scheduling in low earth orbit(LEO)sat...With the advancements of software defined network(SDN)and network function virtualization(NFV),service function chain(SFC)placement becomes a crucial enabler for flexible resource scheduling in low earth orbit(LEO)satellite networks.While due to the scarcity of bandwidth resources and dynamic topology of LEO satellites,the static SFC placement schemes may cause performance degradation,resource waste and even service failure.In this paper,we consider migration and establish an online migration model,especially considering the dynamic topology.Given the scarcity of bandwidth resources,the model aims to maximize the total number of accepted SFCs while incurring as little bandwidth cost of SFC transmission and migration as possible.Due to its NP-hardness,we propose a heuristic minimized dynamic SFC migration(MDSM)algorithm that only triggers the migration procedure when new SFCs are rejected.Simulation results demonstrate that MDSM achieves a performance close to the upper bound with lower complexity.展开更多
Background: The mechanisms by which acupuncture affects poststroke cognitive impairment (PSCI) remain unclear. Objective: To investigate brain functional network (BFN) changes in patients with PSCI after acupuncture t...Background: The mechanisms by which acupuncture affects poststroke cognitive impairment (PSCI) remain unclear. Objective: To investigate brain functional network (BFN) changes in patients with PSCI after acupuncture therapy. Methods: Twenty-two PSCI patients who underwent acupuncture therapy in our hospital were enrolled as research subjects. Another 14 people matched for age, sex, and education level were included in the normal control (HC) group. All the subjects underwent resting-state functional magnetic resonance imaging (rs-fMRI) scans;the PSCI patients underwent one scan before acupuncture therapy and another after. The network metric difference between PSCI patients and HCs was analyzed via the independent-sample t test, whereas the paired-sample t test was employed to analyze the network metric changes in PSCI patients before vs. after treatment. Results: Small-world network attributes were observed in both groups for sparsities between 0.1 and 0.28. Compared with the HC group, the PSCI group presented significantly lower values for the global topological properties (γ, Cp, and Eloc) of the brain;significantly greater values for the nodal attributes of betweenness centrality in the CUN. L and the HES. R, degree centrality in the SFGdor. L, PCG. L, IPL. L, and HES. R, and nodal local efficiency in the ORBsup. R, ORBsupmed. R, DCG. L, SMG. R, and TPOsup. L;and decreased degree centrality in the MFG. R, IFGoperc. R, and SOG. R. After treatment, PSCI patients presented increased degree centrality in the LING.L, LING.R, and IOG. L and nodal local efficiency in PHG. L, IOG. R, FFG. L, and the HES. L, and decreased betweenness centrality in the PCG. L and CUN. L, degree centrality in the ORBsupmed. R, and nodal local efficiency in ANG. R. Conclusion: Cognitive decline in PSCI patients may be related to BFN disorders;acupuncture therapy may modulate the topological properties of the BFNs of PSCI patients.展开更多
To investigate changes of functional activation areas of the cerebral cortex and the connectivity of motor cortex networks (MCNs) in stroke patients during the recovery, five patients with the infarct in their left ...To investigate changes of functional activation areas of the cerebral cortex and the connectivity of motor cortex networks (MCNs) in stroke patients during the recovery, five patients with the infarct in their left hemispheres are recruited. Functional magnetic resonance imaging (fMRI) is performed in the second, fourth, eighth, and sixteenth weeks after the stroke. Images are analyzed using the professional software SPM5 to obtain the bilateral activation of the motor cortex in left and right handgrip tests. MCN data are extracted from the active areas, and the structural and functional characteristic parameters are computed to indicate the connectivity of the network. Results show that the ipsilesional hemisphere recruits more areas with less active extent during the handgrip test, compared with the contralesional hemisphere. MCN shows a higher overall degree of statistical independence and more statistical dependence among motor areas with the gradual recovery. It can help physicians understand the recovery mechanism.展开更多
A novel nonlinear adaptive control method is presented for a near-space hypersonic vehicle (NHV) in the presence of strong uncertainties and disturbances. The control law consists of the optimal generalized predicti...A novel nonlinear adaptive control method is presented for a near-space hypersonic vehicle (NHV) in the presence of strong uncertainties and disturbances. The control law consists of the optimal generalized predictive controller (OGPC) and the functional link network (FLN) direct adaptive law. OGPC is a continuous-time nonlinear predictive control law. The FLN adaptive law is used to offset the unknown uncertainties and disturbances in a flight through the online learning. The learning process does not need any offline training phase. The stability analyses of the NHV close-loop system are provided and it is proved that the system error and the weight learning error are uniformly ultimately hounded. Simulation results show the satisfactory performance of the con- troller for the attitude tracking.展开更多
A constructive-pruning hybrid method (CPHM) for radial basis function (RBF) networks is proposed to improve the prediction accuracy of ash fusion temperatures (AFT). The CPHM incorporates the advantages of the c...A constructive-pruning hybrid method (CPHM) for radial basis function (RBF) networks is proposed to improve the prediction accuracy of ash fusion temperatures (AFT). The CPHM incorporates the advantages of the construction algorithm and the pruning algorithm of neural networks, and the training process of the CPHM is divided into two stages: rough tuning and fine tuning. In rough tuning, new hidden units are added to the current network until some performance index is satisfied. In fine tuning, the network structure and the model parameters are further adjusted. And, based on components of coal ash, a model using the CPHM is established to predict the AFT. The results show that the CPHM prediction model is characterized by its high precision, compact network structure, as well as strong generalization ability and robustness.展开更多
This paper studies the generalization capability of feedforward neural networks (FNN).The mechanism of FNNs for classification is investigated from the geometric and probabilistic viewpoints. It is pointed out that th...This paper studies the generalization capability of feedforward neural networks (FNN).The mechanism of FNNs for classification is investigated from the geometric and probabilistic viewpoints. It is pointed out that the outputs of the output layer in the FNNs for classification correspond to the estimates of posteriori probability of the input pattern samples with desired outputs 1 or 0. The theorem for the generalized kernel function in the radial basis function networks (RBFN) is given. For an 2-layer perceptron network (2-LPN). an idea of using extended samples to improve generalization capability is proposed. Finally. the experimental results of radar target classification are given to verify the generaliztion capability of the RBFNs.展开更多
Studies have shown that functional network connection models can be used to study brain net- work changes in patients with schizophrenia. In this study, we inferred that these models could also be used to explore func...Studies have shown that functional network connection models can be used to study brain net- work changes in patients with schizophrenia. In this study, we inferred that these models could also be used to explore functional network connectivity changes in stroke patients. We used independent component analysis to find the motor areas of stroke patients, which is a novel way to determine these areas. In this study, we collected functional magnetic resonance imaging datasets from healthy controls and right-handed stroke patients following their first ever stroke. Using independent component analysis, six spatially independent components highly correlat- ed to the experimental paradigm were extracted. Then, the functional network connectivity of both patients and controls was established to observe the differences between them. The results showed that there were 11 connections in the model in the stroke patients, while there were only four connections in the healthy controls. Further analysis found that some damaged connections may be compensated for by new indirect connections or circuits produced after stroke. These connections may have a direct correlation with the degree of stroke rehabilitation. Our findings suggest that functional network connectivity in stroke patients is more complex than that in hea- lthy controls, and that there is a compensation loop in the functional network following stroke. This implies that functional network reorganization plays a very important role in the process of rehabilitation after stroke.展开更多
Near-infrared (NIR) spectroscopy combined with chemometrics techniques was used to classify the pure bayberry juice and the one adulterated with 10% (w/w) and 20% (w/w) water. Principal component analysis (PCA) was ap...Near-infrared (NIR) spectroscopy combined with chemometrics techniques was used to classify the pure bayberry juice and the one adulterated with 10% (w/w) and 20% (w/w) water. Principal component analysis (PCA) was applied to reduce the dimensions of spectral data, give information regarding a potential capability of separation of objects, and provide principal component (PC) scores for radial basis function neural networks (RBFNN). RBFNN was used to detect bayberry juice adulterant. Multiplicative scatter correction (MSC) and standard normal variate (SNV) transformation were used to preprocess spectra. The results demonstrate that PC-RBFNN with optimum parameters can separate pure bayberry juice samples from water-adulterated bayberry at a recognition rate of 97.62%, but cannot clearly detect water levels in the adulterated bayberry juice. We conclude that NIR technology can be successfully applied to detect water-adulterated bayberry juice.展开更多
The control law design for a near-space hypersonic vehicle(NHV) is highly challenging due to its inherent nonlinearity,plant uncertainties and sensitivity to disturbances.This paper presents a novel functional link ...The control law design for a near-space hypersonic vehicle(NHV) is highly challenging due to its inherent nonlinearity,plant uncertainties and sensitivity to disturbances.This paper presents a novel functional link network(FLN) control method for an NHV with dynamical thrust and parameter uncertainties.The approach devises a new partially-feedback-functional-link-network(PFFLN) adaptive law and combines it with the nonlinear generalized predictive control(NGPC) algorithm.The PFFLN is employed for approximating uncertainties in flight.Its weights are online tuned based on Lyapunov stability theorem for the first time.The learning process does not need any offline training phase.Additionally,a robust controller with an adaptive gain is designed to offset the approximation error.Finally,simulation results show a satisfactory performance for the NHV attitude tracking,and also illustrate the controller's robustness.展开更多
Deep excavation during the construction of underground systems can cause movement on the ground,especially in soft clay layers.At high levels,excessive ground movements can lead to severe damage to adjacent structures...Deep excavation during the construction of underground systems can cause movement on the ground,especially in soft clay layers.At high levels,excessive ground movements can lead to severe damage to adjacent structures.In this study,finite element analyses(FEM)and the hardening small strain(HSS)model were performed to investigate the deflection of the diaphragm wall in the soft clay layer induced by braced excavations.Different geometric and mechanical properties of the wall were investigated to study the deflection behavior of the wall in soft clays.Accordingly,1090 hypothetical cases were surveyed and simulated based on the HSS model and FEM to evaluate the wall deflection behavior.The results were then used to develop an intelligent model for predicting wall deflection using the functional linked neural network(FLNN)with different functional expansions and activation functions.Although the FLNN is a novel approach to predict wall deflection;however,in order to improve the accuracy of the FLNN model in predicting wall deflection,three swarm-based optimization algorithms,such as artificial bee colony(ABC),Harris’s hawk’s optimization(HHO),and hunger games search(HGS),were hybridized to the FLNN model to generate three novel intelligent models,namely ABC-FLNN,HHO-FLNN,HGS-FLNN.The results of the hybrid models were then compared with the basic FLNN and MLP models.They revealed that FLNN is a good solution for predicting wall deflection,and the application of different functional expansions and activation functions has a significant effect on the outcome predictions of the wall deflection.It is remarkably interesting that the performance of the FLNN model was better than the MLP model with a mean absolute error(MAE)of 19.971,root-mean-squared error(RMSE)of 24.574,and determination coefficient(R^(2))of 0.878.Meanwhile,the performance of the MLP model only obtained an MAE of 20.321,RMSE of 27.091,and R^(2)of 0.851.Furthermore,the results also indicated that the proposed hybrid models,i.e.,ABC-FLNN,HHO-FLNN,HGS-FLNN,yielded more superior performances than those of the FLNN and MLP models in terms of the prediction of deflection behavior of diaphragm walls with an MAE in the range of 11.877 to 12.239,RMSE in the range of 15.821 to 16.045,and R^(2)in the range of 0.949 to 0.951.They can be used as an alternative tool to simulate diaphragm wall deflections under different conditions with a high degree of accuracy.展开更多
In this paper, adaptive identification and control of nonlinear dynamical systems are investigated using radial basis function networks (RBF). Firstly, a novel approach to train the RBF is introduced, which employs an...In this paper, adaptive identification and control of nonlinear dynamical systems are investigated using radial basis function networks (RBF). Firstly, a novel approach to train the RBF is introduced, which employs an adaptive fuzzy generalized learning vector quantization (AFGLVQ) technique and recursive least squares algorithm with variable forgetting factor (VRLS). The AFGLVQ adjusts the centers of the RBF while the VRLS updates the connection weights of the network. The identification algorithm has the properties of rapid convergence and persistent adaptability that make it suitable for real-time control. Secondly, on the basis of the one-step ahead RBF predictor, the control law is optimized iteratively through a numerical stable Davidon's least squares-based (SDLS) minimization approach. Four nonlinear examples are simulated to demonstrate the effectiveness of the identification and control algorithms.展开更多
Rhythm of brain activities represents oscillations of postsynaptic potentials in neocortex, therefore it can serve as an indicator of the brain activity state. In order to check the connectivity of brain rhythm, this ...Rhythm of brain activities represents oscillations of postsynaptic potentials in neocortex, therefore it can serve as an indicator of the brain activity state. In order to check the connectivity of brain rhythm, this paper develops a new method of constructing functional network based on phase synchronization. Electroencephalogram (EEG) data were collected while subjects looking at a green cross in two states, performing an attention task and relaxing with eyes-open. The EEG from these two states was filtered by three band-pass filters to obtain signals of theta (4-7 Hz), alpha (8-13 Hz) and beta (14-30 Hz) bands. Mean resultant length was used to estimate strength of phase synchronization in three bands to construct networks of both states, and mean degree K and cluster coefficient C of networks were calculated as a function of threshold. The result shows higher cluster coetticient in the attention state than in the eyes-open state in all three bands, suggesting that cluster coefficient reflects brain state. In addition, an obvious fronto-parietal network is found in the attention state, which is a well-known attention network. These results indicate that attention modulates the fronto-parietal connectivity in different modes as compared with the eyes-open state. Taken together this method is an objective and important tool to study the properties of neural networks of brain rhythm,展开更多
基金sponsored by the National Defense Science and Technology Key Laboratory Fund(Grant No.61422062205)the Equipment Pre-Research Fund(Grant No.JCKYS2022LD9)。
文摘Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby contributing to the advancement of camouflage evaluation.In this study,images with various camouflage effects were presented to observers to generate electroencephalography(EEG)signals,which were then used to construct a brain functional network.The topological parameters of the network were subsequently extracted and input into a machine learning model for training.The results indicate that most of the classifiers achieved accuracy rates exceeding 70%.Specifically,the Logistic algorithm achieved an accuracy of 81.67%.Therefore,it is possible to predict target camouflage effectiveness with high accuracy without the need to calculate discovery probability.The proposed method fully considers the aspects of human visual and cognitive processes,overcomes the subjectivity of human interpretation,and achieves stable and reliable accuracy.
文摘Landslides are common natural hazards occurring in most parts of the world and have considerable adverse economic effects. Residual shear strength of clay is one of the most important factors in the determination of stability of slopes or landslides. This effect is more pronounced in sensitive clays which show large changes in shear strength from peak to residual states. This study analyses the prediction of the residual strength of clay based on a new prediction model, functional networks(FN) using data available in the literature. The performance of FN was compared with support vector machine(SVM) and artificial neural network(ANN) based on statistical parameters like correlation coefficient(R), Nash–Sutcliff coefficient of efficiency(E), absolute average error(AAE), maximum average error(MAE) and root mean square error(RMSE). Based on R and E parameters, FN is found to be a better prediction tool than ANN for the given data. However, the R and E values for FN are less than SVM. A prediction equation is presented that can be used by practicing geotechnical engineers. A sensitivity analysis is carried out to ascertain the importance of various inputs in the prediction of the output.
基金supported by the National Natural Science Foundation of China (No.51877013),(ZJ),(http://www.nsfc.gov.cn/)the Jiangsu Provincial Key Research and Development Program (No.BE2021636),(ZJ),(http://kxjst.jiangsu.gov.cn/)+1 种基金the Science and Technology Project of Changzhou City (No.CE20205056),(ZJ),(http://kjj.changzhou.gov.cn/)by Qing Lan Project of Jiangsu Province (no specific grant number),(ZJ),(http://jyt.jiangsu.gov.cn/).
文摘The structure and function of brain networks have been altered in patients with end-stage renal disease(ESRD).Manifold regularization(MR)only considers the pairing relationship between two brain regions and cannot represent functional interactions or higher-order relationships between multiple brain regions.To solve this issue,we developed a method to construct a dynamic brain functional network(DBFN)based on dynamic hypergraph MR(DHMR)and applied it to the classification of ESRD associated with mild cognitive impairment(ESRDaMCI).The construction of DBFN with Pearson’s correlation(PC)was transformed into an optimization model.Node convolution and hyperedge convolution superposition were adopted to dynamically modify the hypergraph structure,and then got the dynamic hypergraph to form the manifold regular terms of the dynamic hypergraph.The DHMR and L_(1) norm regularization were introduced into the PC-based optimization model to obtain the final DHMR-based DBFN(DDBFN).Experiment results demonstrated the validity of the DDBFN method by comparing the classification results with several related brain functional network construction methods.Our work not only improves better classification performance but also reveals the discriminative regions of ESRDaMCI,providing a reference for clinical research and auxiliary diagnosis of concomitant cognitive impairments.
基金The authors thank the College of Information and Engineering Taishan Medical University colleagues for assistance with data collection and the manuscript comments. Special thanks to Polly and Xiaochen Xu for suggestions on writing in the English language. The authors are grateful to the anonymous referees for their valuable comments and suggestions. This research was supported by the Natural Science Foundation of Shandong (No. ZR2013FL031), State Accident Prevention Key Technology of Work Safety Program (No. 2013-084), Work Safety Science Technology Development Program of Shandong (No. LAJK2013-137), High-level Training Project of Taishan Medical University (No. 2013GCC09).
文摘The purpose of the paper is to provide a way to model the brain functional network based on the complex networks with brain anatomical architecture. We introduce the brain structural and functional researches, and delineate the brain anatomical and functional networks based on complex networks, then we discuss the brain functional complex network models; at last we put forward the brain functional networks modeling process and the data processing with fMRI (functional magnetic resonance imaging) in detailed.
基金supported by the National Natural Science Foundation of China(62076157 and 61703253)the Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province(20210033)the National Institutes of Health(R01MH123610 and R01EB006841).
文摘Functional networks(FNs)hold significant promise in understanding brain function.Independent component analysis(ICA)has been applied in estimating FNs from functional magnetic resonance imaging(fMRI).However,determining an optimal model order for ICA remains challenging,leading to criticism about the reliability of FN estimation.Here,we propose a SMART(splitting-merging assisted reliable)ICA method that automatically extracts reliable FNs by clustering independent components(ICs)obtained from multi-model-order ICA using a simplified graph while providing linkages among FNs deduced from different-model orders.We extend SMART ICA to multi-subject fMRI analysis,validating its effectiveness using simulated and real fMRI data.Based on simulated data,the method accurately estimates both group-common and group-unique components and demonstrates robustness to parameters.Using two age-matched cohorts of resting fMRI data comprising 1,950 healthy subjects,the resulting reliable group-level FNs are greatly similar between the two cohorts,and interestingly the subject-specific FNs show progressive changes while age increases.Furthermore,both small-scale and large-scale brain FN templates are provided as benchmarks for future studies.Taken together,SMART ICA can automatically obtain reliable FNs in analyzing multi-subject fMRI data,while also providing linkages between different FNs.
基金supported by the National Natural Science Foundation of China,Nos.81871836(to MZ),82172554(to XH),and 81802249(to XH),81902301(to JW)the National Key R&D Program of China,Nos.2018YFC2001600(to JX)and 2018YFC2001604(to JX)+3 种基金Shanghai Rising Star Program,No.19QA1409000(to MZ)Shanghai Municipal Commission of Health and Family Planning,No.2018YQ02(to MZ)Shanghai Youth Top Talent Development PlanShanghai“Rising Stars of Medical Talent”Youth Development Program,No.RY411.19.01.10(to XH)。
文摘Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery.
基金supported by the National Natural Science Foundation of China(No.51877013),(ZJ),(http://www.nsfc.gov.cn/)the Natural Science Foundation of Jiangsu Province(No.BK20181463),(ZJ),(http://kxjst.jiangsu.gov.cn/)sponsored by Qing Lan Project of Jiangsu Province(no specific grant number),(ZJ),(http://jyt.jiangsu.gov.cn/).
文摘Currently,functional connectomes constructed from neuroimaging data have emerged as a powerful tool in identifying brain disorders.If one brain disease just manifests as some cognitive dysfunction,it means that the disease may affect some local connectivity in the brain functional network.That is,there are functional abnormalities in the sub-network.Therefore,it is crucial to accurately identify them in pathological diagnosis.To solve these problems,we proposed a sub-network extraction method based on graph regularization nonnegative matrix factorization(GNMF).The dynamic functional networks of normal subjects and early mild cognitive impairment(eMCI)subjects were vectorized and the functional connection vectors(FCV)were assembled to aggregation matrices.Then GNMF was applied to factorize the aggregation matrix to get the base matrix,in which the column vectors were restored to a common sub-network and a distinctive sub-network,and visualization and statistical analysis were conducted on the two sub-networks,respectively.Experimental results demonstrated that,compared with other matrix factorization methods,the proposed method can more obviously reflect the similarity between the common subnetwork of eMCI subjects and normal subjects,as well as the difference between the distinctive sub-network of eMCI subjects and normal subjects,Therefore,the high-dimensional features in brain functional networks can be best represented locally in the lowdimensional space,which provides a new idea for studying brain functional connectomes.
文摘Functional brain networks (FBN) based on resting-state functional magnetic resonance imaging (rs-fMRI) have become an important tool for exploring underlying organization patterns in the brain, which can provide an objective basis for brain disorders such as autistic spectrum disorder (ASD). Due to its importance, researchers have proposed a number of FBN estimation methods. However, most existing methods only model a type of functional connection relationship between brain regions-of-interest (ROIs), such as partial correlation or full correlation, which is difficult to fully capture the subtle connections among ROIs since these connections are extremely complex. Motivated by the multi-view learning, in this study we propose a novel Consistent and Specific Multi-view FBNs Fusion (CSMF) approach. Concretely, we first construct multi-view FBNs (i.e., multiple types of FBNs modelling various relationships among ROIs), and then these FBNs are decomposed into a consistent representation matrix and their own specific matrices which capture their common and unique information, respectively. Lastly, to obtain a better brain representation, it is fusing the consistent and specific representation matrices in the latent representation spaces of FBNs, but not directly fusing the original FBNs. This potentially makes it more easily to find the comprehensively brain connections. The experimental results of ASD identification on the ABIDE datasets validate the effectiveness of our proposed method compared to several state-of-the-art methods. Our proposed CSMF method achieved 72.8% and 76.67% classification performance on the ABIDE dataset.
基金supported in part by the National Natural Science Foundation of China(NSFC)under grant numbers U22A2007 and 62171010the Open project of Satellite Internet Key Laboratory in 2022(Project 3:Research on Spaceborne Lightweight Core Network and Intelligent Collaboration)the Beijing Natural Science Foundation under grant number L212003.
文摘With the advancements of software defined network(SDN)and network function virtualization(NFV),service function chain(SFC)placement becomes a crucial enabler for flexible resource scheduling in low earth orbit(LEO)satellite networks.While due to the scarcity of bandwidth resources and dynamic topology of LEO satellites,the static SFC placement schemes may cause performance degradation,resource waste and even service failure.In this paper,we consider migration and establish an online migration model,especially considering the dynamic topology.Given the scarcity of bandwidth resources,the model aims to maximize the total number of accepted SFCs while incurring as little bandwidth cost of SFC transmission and migration as possible.Due to its NP-hardness,we propose a heuristic minimized dynamic SFC migration(MDSM)algorithm that only triggers the migration procedure when new SFCs are rejected.Simulation results demonstrate that MDSM achieves a performance close to the upper bound with lower complexity.
文摘Background: The mechanisms by which acupuncture affects poststroke cognitive impairment (PSCI) remain unclear. Objective: To investigate brain functional network (BFN) changes in patients with PSCI after acupuncture therapy. Methods: Twenty-two PSCI patients who underwent acupuncture therapy in our hospital were enrolled as research subjects. Another 14 people matched for age, sex, and education level were included in the normal control (HC) group. All the subjects underwent resting-state functional magnetic resonance imaging (rs-fMRI) scans;the PSCI patients underwent one scan before acupuncture therapy and another after. The network metric difference between PSCI patients and HCs was analyzed via the independent-sample t test, whereas the paired-sample t test was employed to analyze the network metric changes in PSCI patients before vs. after treatment. Results: Small-world network attributes were observed in both groups for sparsities between 0.1 and 0.28. Compared with the HC group, the PSCI group presented significantly lower values for the global topological properties (γ, Cp, and Eloc) of the brain;significantly greater values for the nodal attributes of betweenness centrality in the CUN. L and the HES. R, degree centrality in the SFGdor. L, PCG. L, IPL. L, and HES. R, and nodal local efficiency in the ORBsup. R, ORBsupmed. R, DCG. L, SMG. R, and TPOsup. L;and decreased degree centrality in the MFG. R, IFGoperc. R, and SOG. R. After treatment, PSCI patients presented increased degree centrality in the LING.L, LING.R, and IOG. L and nodal local efficiency in PHG. L, IOG. R, FFG. L, and the HES. L, and decreased betweenness centrality in the PCG. L and CUN. L, degree centrality in the ORBsupmed. R, and nodal local efficiency in ANG. R. Conclusion: Cognitive decline in PSCI patients may be related to BFN disorders;acupuncture therapy may modulate the topological properties of the BFNs of PSCI patients.
基金Supported by the National Natural Science Foundation of China (30670543)~~
文摘To investigate changes of functional activation areas of the cerebral cortex and the connectivity of motor cortex networks (MCNs) in stroke patients during the recovery, five patients with the infarct in their left hemispheres are recruited. Functional magnetic resonance imaging (fMRI) is performed in the second, fourth, eighth, and sixteenth weeks after the stroke. Images are analyzed using the professional software SPM5 to obtain the bilateral activation of the motor cortex in left and right handgrip tests. MCN data are extracted from the active areas, and the structural and functional characteristic parameters are computed to indicate the connectivity of the network. Results show that the ipsilesional hemisphere recruits more areas with less active extent during the handgrip test, compared with the contralesional hemisphere. MCN shows a higher overall degree of statistical independence and more statistical dependence among motor areas with the gradual recovery. It can help physicians understand the recovery mechanism.
基金Supported by the National Nature Science Foundation of China (90716028)~~
文摘A novel nonlinear adaptive control method is presented for a near-space hypersonic vehicle (NHV) in the presence of strong uncertainties and disturbances. The control law consists of the optimal generalized predictive controller (OGPC) and the functional link network (FLN) direct adaptive law. OGPC is a continuous-time nonlinear predictive control law. The FLN adaptive law is used to offset the unknown uncertainties and disturbances in a flight through the online learning. The learning process does not need any offline training phase. The stability analyses of the NHV close-loop system are provided and it is proved that the system error and the weight learning error are uniformly ultimately hounded. Simulation results show the satisfactory performance of the con- troller for the attitude tracking.
基金The National Natural Science Foundation of China(No.60875035)the Natural Science Foundation of Jiangsu Province(No.BK2008294)the National High Technology Research and Development Program of China(863 Program)(No.2006AA05A107)
文摘A constructive-pruning hybrid method (CPHM) for radial basis function (RBF) networks is proposed to improve the prediction accuracy of ash fusion temperatures (AFT). The CPHM incorporates the advantages of the construction algorithm and the pruning algorithm of neural networks, and the training process of the CPHM is divided into two stages: rough tuning and fine tuning. In rough tuning, new hidden units are added to the current network until some performance index is satisfied. In fine tuning, the network structure and the model parameters are further adjusted. And, based on components of coal ash, a model using the CPHM is established to predict the AFT. The results show that the CPHM prediction model is characterized by its high precision, compact network structure, as well as strong generalization ability and robustness.
文摘This paper studies the generalization capability of feedforward neural networks (FNN).The mechanism of FNNs for classification is investigated from the geometric and probabilistic viewpoints. It is pointed out that the outputs of the output layer in the FNNs for classification correspond to the estimates of posteriori probability of the input pattern samples with desired outputs 1 or 0. The theorem for the generalized kernel function in the radial basis function networks (RBFN) is given. For an 2-layer perceptron network (2-LPN). an idea of using extended samples to improve generalization capability is proposed. Finally. the experimental results of radar target classification are given to verify the generaliztion capability of the RBFNs.
基金supported by the National Natural Science Foundation of China,No.60905024
文摘Studies have shown that functional network connection models can be used to study brain net- work changes in patients with schizophrenia. In this study, we inferred that these models could also be used to explore functional network connectivity changes in stroke patients. We used independent component analysis to find the motor areas of stroke patients, which is a novel way to determine these areas. In this study, we collected functional magnetic resonance imaging datasets from healthy controls and right-handed stroke patients following their first ever stroke. Using independent component analysis, six spatially independent components highly correlat- ed to the experimental paradigm were extracted. Then, the functional network connectivity of both patients and controls was established to observe the differences between them. The results showed that there were 11 connections in the model in the stroke patients, while there were only four connections in the healthy controls. Further analysis found that some damaged connections may be compensated for by new indirect connections or circuits produced after stroke. These connections may have a direct correlation with the degree of stroke rehabilitation. Our findings suggest that functional network connectivity in stroke patients is more complex than that in hea- lthy controls, and that there is a compensation loop in the functional network following stroke. This implies that functional network reorganization plays a very important role in the process of rehabilitation after stroke.
基金supported by the National Natural Science Foundation of China (Nos. 60778024 and 30825027)the National Basic Re-search Program (973) of China (No. 2006BAD11A12)
文摘Near-infrared (NIR) spectroscopy combined with chemometrics techniques was used to classify the pure bayberry juice and the one adulterated with 10% (w/w) and 20% (w/w) water. Principal component analysis (PCA) was applied to reduce the dimensions of spectral data, give information regarding a potential capability of separation of objects, and provide principal component (PC) scores for radial basis function neural networks (RBFNN). RBFNN was used to detect bayberry juice adulterant. Multiplicative scatter correction (MSC) and standard normal variate (SNV) transformation were used to preprocess spectra. The results demonstrate that PC-RBFNN with optimum parameters can separate pure bayberry juice samples from water-adulterated bayberry at a recognition rate of 97.62%, but cannot clearly detect water levels in the adulterated bayberry juice. We conclude that NIR technology can be successfully applied to detect water-adulterated bayberry juice.
基金supported by the National Natural Science Foundation of China (9071602860974106)
文摘The control law design for a near-space hypersonic vehicle(NHV) is highly challenging due to its inherent nonlinearity,plant uncertainties and sensitivity to disturbances.This paper presents a novel functional link network(FLN) control method for an NHV with dynamical thrust and parameter uncertainties.The approach devises a new partially-feedback-functional-link-network(PFFLN) adaptive law and combines it with the nonlinear generalized predictive control(NGPC) algorithm.The PFFLN is employed for approximating uncertainties in flight.Its weights are online tuned based on Lyapunov stability theorem for the first time.The learning process does not need any offline training phase.Additionally,a robust controller with an adaptive gain is designed to offset the approximation error.Finally,simulation results show a satisfactory performance for the NHV attitude tracking,and also illustrate the controller's robustness.
基金financially supported by the Natural Science Foundation of Hunan Province(2021JJ30679)。
文摘Deep excavation during the construction of underground systems can cause movement on the ground,especially in soft clay layers.At high levels,excessive ground movements can lead to severe damage to adjacent structures.In this study,finite element analyses(FEM)and the hardening small strain(HSS)model were performed to investigate the deflection of the diaphragm wall in the soft clay layer induced by braced excavations.Different geometric and mechanical properties of the wall were investigated to study the deflection behavior of the wall in soft clays.Accordingly,1090 hypothetical cases were surveyed and simulated based on the HSS model and FEM to evaluate the wall deflection behavior.The results were then used to develop an intelligent model for predicting wall deflection using the functional linked neural network(FLNN)with different functional expansions and activation functions.Although the FLNN is a novel approach to predict wall deflection;however,in order to improve the accuracy of the FLNN model in predicting wall deflection,three swarm-based optimization algorithms,such as artificial bee colony(ABC),Harris’s hawk’s optimization(HHO),and hunger games search(HGS),were hybridized to the FLNN model to generate three novel intelligent models,namely ABC-FLNN,HHO-FLNN,HGS-FLNN.The results of the hybrid models were then compared with the basic FLNN and MLP models.They revealed that FLNN is a good solution for predicting wall deflection,and the application of different functional expansions and activation functions has a significant effect on the outcome predictions of the wall deflection.It is remarkably interesting that the performance of the FLNN model was better than the MLP model with a mean absolute error(MAE)of 19.971,root-mean-squared error(RMSE)of 24.574,and determination coefficient(R^(2))of 0.878.Meanwhile,the performance of the MLP model only obtained an MAE of 20.321,RMSE of 27.091,and R^(2)of 0.851.Furthermore,the results also indicated that the proposed hybrid models,i.e.,ABC-FLNN,HHO-FLNN,HGS-FLNN,yielded more superior performances than those of the FLNN and MLP models in terms of the prediction of deflection behavior of diaphragm walls with an MAE in the range of 11.877 to 12.239,RMSE in the range of 15.821 to 16.045,and R^(2)in the range of 0.949 to 0.951.They can be used as an alternative tool to simulate diaphragm wall deflections under different conditions with a high degree of accuracy.
文摘In this paper, adaptive identification and control of nonlinear dynamical systems are investigated using radial basis function networks (RBF). Firstly, a novel approach to train the RBF is introduced, which employs an adaptive fuzzy generalized learning vector quantization (AFGLVQ) technique and recursive least squares algorithm with variable forgetting factor (VRLS). The AFGLVQ adjusts the centers of the RBF while the VRLS updates the connection weights of the network. The identification algorithm has the properties of rapid convergence and persistent adaptability that make it suitable for real-time control. Secondly, on the basis of the one-step ahead RBF predictor, the control law is optimized iteratively through a numerical stable Davidon's least squares-based (SDLS) minimization approach. Four nonlinear examples are simulated to demonstrate the effectiveness of the identification and control algorithms.
基金supported by the Young Scientists Fund of the National Natural Science Foundation of China (Grant No. 30800242)
文摘Rhythm of brain activities represents oscillations of postsynaptic potentials in neocortex, therefore it can serve as an indicator of the brain activity state. In order to check the connectivity of brain rhythm, this paper develops a new method of constructing functional network based on phase synchronization. Electroencephalogram (EEG) data were collected while subjects looking at a green cross in two states, performing an attention task and relaxing with eyes-open. The EEG from these two states was filtered by three band-pass filters to obtain signals of theta (4-7 Hz), alpha (8-13 Hz) and beta (14-30 Hz) bands. Mean resultant length was used to estimate strength of phase synchronization in three bands to construct networks of both states, and mean degree K and cluster coefficient C of networks were calculated as a function of threshold. The result shows higher cluster coetticient in the attention state than in the eyes-open state in all three bands, suggesting that cluster coefficient reflects brain state. In addition, an obvious fronto-parietal network is found in the attention state, which is a well-known attention network. These results indicate that attention modulates the fronto-parietal connectivity in different modes as compared with the eyes-open state. Taken together this method is an objective and important tool to study the properties of neural networks of brain rhythm,