The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, ref...The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, referred to as the g-factor anomaly. This anomaly has been calculated theoretically as a power series of the fine structure constant. This document shows that the anomaly is the result of the electron charge thickness. If the thickness were to be zero, g = 2 exactly, and there would be no anomaly. As the thickness increases, the anomaly increases. An equation relating the g-factor and the surface charge thickness is presented. The thickness is calculated to be 0.23% of the electron radius. The cause of the anomaly is very clear, but why is the charge thickness greater than zero? Using the model of the interior structure of the electron previously proposed by the author, it is shown that the non-zero thickness, and thus the g-factor anomaly, are due to the proposed positive charge at the electron center and compressibility of the electron material. The author’s previous publication proposes a theory for splitting the electron into three equal charges when subjected to a strong external magnetic field. That theory is revised in this document, and the result is an error reduced to 0.4% in the polar angle where the splits occur and a reduced magnetic field required to cause the splits.展开更多
Introduction and Objectives: Soil-Transmitted-Helminthiasis (STH) is a public health problem in Cameroon. The control strategies currently in place, particularly chemoprevention, has shortcomings linked to the target ...Introduction and Objectives: Soil-Transmitted-Helminthiasis (STH) is a public health problem in Cameroon. The control strategies currently in place, particularly chemoprevention, has shortcomings linked to the target population, which are school-age children. The objective was to determine the prevalence and the risk factors associated with geo-helminthiasis in children aged 0 to 3 years in a rural health district. Method: From December 2020 to May 2021, a descriptive and analytical cross-sectional study of 376 children between 6 and 36 months was carried out in the Akonolinga health district. This was a cluster sampling in 4 health areas. Stool samples were collected and analysed using the mini-FLOTAC method. The results expressed as the number of eggs per gram of stool. A questionnaire on socio-demographic and lifestyle data was administered to the parents. The Chi-squared test was used to measure the association between geo-helminth infection and the data collected. A multivariate analysis using logistic regression was performed (p 0.05). Results: The prevalence of STH was 19.4% (Ascaris lumbricoides: 16% and Trichuris trichiura: 8%). Risk factors were: consumption of contaminated water (AOR = 1.93 [1.03 - 3.6];p = 0.040), early contact of the child with the ground (before age of 4 months) (AOR = 4.9 [2.1 - 11.37];p .001), habit of walking barefoot (AOR = 2.91 [1.1 - 7.97];p = 0.038), and living in a habitat with unpaved ground (AOR = 7.4 [1.55 - 35.7];p = 0.012). Conclusion: The prevalence of STHs in infants was high. Preventive chemotherapy should be extended to this age-group, and other measures intensified.展开更多
Introduction: Acute respiratory infections remain one of the main causes of mortality in children aged 0 to 5. This work aimed to study the associated factors with the occurrence of acute respiratory infections in chi...Introduction: Acute respiratory infections remain one of the main causes of mortality in children aged 0 to 5. This work aimed to study the associated factors with the occurrence of acute respiratory infections in children 0 to 5 years old in Yénawa, Cotonou in 2023. Subjects and Method: It was an analytical cross-sectional study of children aged 0 - 5 years and their mothers in Yénawa, selected by four-degree random sampling. The sampling size, calculated using the Schwartz formula, was 126 children and 126 mothers. The dependent variable was the occurrence of acute respiratory infections. The independent variables were classified into four groups: socio-demographic and economic characteristics, behavioral factors, child-related factors, and environmental factors. Data collected by observation and questionnaire survey were analyzed using STATA version 15 software. Associated factors were investigated by bivariate analysis and multiple logistic regression, at the 5% significance level. Results: A total of 126 children aged 0 - 5 years and 126 mothers were surveyed, aged 23.5 (11 - 36) months and 30 (18 - 48) years respectively. The prevalence of acute respiratory infections was 74.60% (CI95% = 66.89 to 82.30). The associated factors were the mother’s age between 18 and 28 (OR = 10.77;CI95% = 1.89 to 61.27;p = 0.007), the use of charcoal/wood for cooking (OR = 7.36;IC = 1.99 to 27.10;p = 0.003)), children's poor personal hygiene (OR = 8.87;IC = 2.92 to 26.97;p 0.001)), and cohabitation with domestic animals (OR = 7.27;IC = 1.67 to 31.71;p = 0.015). Conclusion: Communicating with mothers about the factors identified will help reduce the prevalence of acute respiratory infections in children aged 0 to 5.展开更多
Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target ...Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target techniques, with a specific emphasis on targeting the vascular endothelial growth factor, but have not reached ideal therapeutic efficacy. In response to this issue, our study introduced a novel nanoparticle system known as CS-siRNA/PEITC&L-cRGD NPs. These chitosan-based nanoparticles have been recognized for their excellent biocompatibility and ability to deliver genes. To enhance their targeted delivery capability, they were combined with a cyclic RGD peptide (cRGD). Targeted co-delivery of gene and chemotherapeutic agents was achieved through the use of a negatively charged lipid shell and cRGD, which possesses high affinity for integrin αvβ3 overexpressed in tumor cells and neovasculature. In this multifaceted approach, co-delivery of VEGF siRNA and phenethyl isothiocyanate (PEITC) was employed to target both tumor vascular endothelial cells and tumor cells simultaneously. The co-delivery of VEGF siRNA and PEITC could achieve precise silencing of VEGF, inhibit the accumulation of HIF-1α under hypoxic conditions, and induce apoptosis in tumor cells. In summary, we have successfully developed a nanoparticle delivery platform that utilizes a dual mechanism of action of anti-tumor angiogenesis and pro-tumor apoptosis, which provides a robust and potent strategy for the delivery of anti-cancer therapeutics.展开更多
四川西部地区地理环境复杂,滑坡空间结构多样且变形剧烈。为有效预防滑坡灾害,需要探究相关区域滑坡危险性可靠评价方法。利用G1-熵权耦合赋权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS...四川西部地区地理环境复杂,滑坡空间结构多样且变形剧烈。为有效预防滑坡灾害,需要探究相关区域滑坡危险性可靠评价方法。利用G1-熵权耦合赋权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS)构建滑坡灾害危险性评价模型,选取高程、降雨、地震动参数等12个评价因子,对雅砻江滑坡灾害危险性进行评价。依据贴近度将滑坡区域分为4个等级,即高危险区(0.75~1)、较高危险区(0.5~0.75)、中等危险区(0.25~0.5)和低危险区(0~0.25)。同时,对比了由差分干涉测量短基线集时序分析(small baseline subset interferometric synthetic aperture radar,SBAS-InSAR)技术得到的4个区域滑坡实测结果和本文评价模型的分析结果。利用G1-熵权耦合赋权TOPSIS得到九龙县烟袋镇桤木林村高生地滑坡、新龙县和平乡甲西村麻西滑坡、德格县年古乡政府滑坡和甘孜县扎科乡达玛滑坡的贴近度分别为0.854、0.686、0.405和0.224,由SBAS-InSAR技术得到滑坡前缘局部变形速率分别为-150、-43、-66、30 mm/a,二者之间有显著的对应关系,证明本文评价模型的准确性。应用G1-熵权耦合赋权TOPSIS法对滑坡危险性评价具有较高的准确性,该方法可为其他地区滑坡地质灾害评价提供参考。展开更多
随着5G技术的不断发展,5G蜂窝网络已被广泛应用于城市地区。然而,基于5G的机会信号定位技术中存在着测距精度不高的问题。针对此问题,提出一种改进型5G机会信号定位算法,该算法将多信号分类(multiple signal classification,MUSIC)算法...随着5G技术的不断发展,5G蜂窝网络已被广泛应用于城市地区。然而,基于5G的机会信号定位技术中存在着测距精度不高的问题。针对此问题,提出一种改进型5G机会信号定位算法,该算法将多信号分类(multiple signal classification,MUSIC)算法与改进的早-晚功率锁相环(phase-locked loop,PLL)结合,不仅简化了锁相环结构,更保证了测距精度;同时搭建了基于5G机会信号定位的原理样机,并对改进算法方法的有效性和可行性进行了验证,试验结果表明伪距均方误差为3.03 m。本文所提出的算法不仅结构简单、系统稳定,而且在测距精度上也有一定的优势。展开更多
文摘The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, referred to as the g-factor anomaly. This anomaly has been calculated theoretically as a power series of the fine structure constant. This document shows that the anomaly is the result of the electron charge thickness. If the thickness were to be zero, g = 2 exactly, and there would be no anomaly. As the thickness increases, the anomaly increases. An equation relating the g-factor and the surface charge thickness is presented. The thickness is calculated to be 0.23% of the electron radius. The cause of the anomaly is very clear, but why is the charge thickness greater than zero? Using the model of the interior structure of the electron previously proposed by the author, it is shown that the non-zero thickness, and thus the g-factor anomaly, are due to the proposed positive charge at the electron center and compressibility of the electron material. The author’s previous publication proposes a theory for splitting the electron into three equal charges when subjected to a strong external magnetic field. That theory is revised in this document, and the result is an error reduced to 0.4% in the polar angle where the splits occur and a reduced magnetic field required to cause the splits.
文摘Introduction and Objectives: Soil-Transmitted-Helminthiasis (STH) is a public health problem in Cameroon. The control strategies currently in place, particularly chemoprevention, has shortcomings linked to the target population, which are school-age children. The objective was to determine the prevalence and the risk factors associated with geo-helminthiasis in children aged 0 to 3 years in a rural health district. Method: From December 2020 to May 2021, a descriptive and analytical cross-sectional study of 376 children between 6 and 36 months was carried out in the Akonolinga health district. This was a cluster sampling in 4 health areas. Stool samples were collected and analysed using the mini-FLOTAC method. The results expressed as the number of eggs per gram of stool. A questionnaire on socio-demographic and lifestyle data was administered to the parents. The Chi-squared test was used to measure the association between geo-helminth infection and the data collected. A multivariate analysis using logistic regression was performed (p 0.05). Results: The prevalence of STH was 19.4% (Ascaris lumbricoides: 16% and Trichuris trichiura: 8%). Risk factors were: consumption of contaminated water (AOR = 1.93 [1.03 - 3.6];p = 0.040), early contact of the child with the ground (before age of 4 months) (AOR = 4.9 [2.1 - 11.37];p .001), habit of walking barefoot (AOR = 2.91 [1.1 - 7.97];p = 0.038), and living in a habitat with unpaved ground (AOR = 7.4 [1.55 - 35.7];p = 0.012). Conclusion: The prevalence of STHs in infants was high. Preventive chemotherapy should be extended to this age-group, and other measures intensified.
文摘Introduction: Acute respiratory infections remain one of the main causes of mortality in children aged 0 to 5. This work aimed to study the associated factors with the occurrence of acute respiratory infections in children 0 to 5 years old in Yénawa, Cotonou in 2023. Subjects and Method: It was an analytical cross-sectional study of children aged 0 - 5 years and their mothers in Yénawa, selected by four-degree random sampling. The sampling size, calculated using the Schwartz formula, was 126 children and 126 mothers. The dependent variable was the occurrence of acute respiratory infections. The independent variables were classified into four groups: socio-demographic and economic characteristics, behavioral factors, child-related factors, and environmental factors. Data collected by observation and questionnaire survey were analyzed using STATA version 15 software. Associated factors were investigated by bivariate analysis and multiple logistic regression, at the 5% significance level. Results: A total of 126 children aged 0 - 5 years and 126 mothers were surveyed, aged 23.5 (11 - 36) months and 30 (18 - 48) years respectively. The prevalence of acute respiratory infections was 74.60% (CI95% = 66.89 to 82.30). The associated factors were the mother’s age between 18 and 28 (OR = 10.77;CI95% = 1.89 to 61.27;p = 0.007), the use of charcoal/wood for cooking (OR = 7.36;IC = 1.99 to 27.10;p = 0.003)), children's poor personal hygiene (OR = 8.87;IC = 2.92 to 26.97;p 0.001)), and cohabitation with domestic animals (OR = 7.27;IC = 1.67 to 31.71;p = 0.015). Conclusion: Communicating with mothers about the factors identified will help reduce the prevalence of acute respiratory infections in children aged 0 to 5.
基金supported by Guangdong Basic and Applied Basic Research Foundation(2023A1515010969)Natural Science Foundation of Top Talent of SZTU(GDRC202305).
文摘Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target techniques, with a specific emphasis on targeting the vascular endothelial growth factor, but have not reached ideal therapeutic efficacy. In response to this issue, our study introduced a novel nanoparticle system known as CS-siRNA/PEITC&L-cRGD NPs. These chitosan-based nanoparticles have been recognized for their excellent biocompatibility and ability to deliver genes. To enhance their targeted delivery capability, they were combined with a cyclic RGD peptide (cRGD). Targeted co-delivery of gene and chemotherapeutic agents was achieved through the use of a negatively charged lipid shell and cRGD, which possesses high affinity for integrin αvβ3 overexpressed in tumor cells and neovasculature. In this multifaceted approach, co-delivery of VEGF siRNA and phenethyl isothiocyanate (PEITC) was employed to target both tumor vascular endothelial cells and tumor cells simultaneously. The co-delivery of VEGF siRNA and PEITC could achieve precise silencing of VEGF, inhibit the accumulation of HIF-1α under hypoxic conditions, and induce apoptosis in tumor cells. In summary, we have successfully developed a nanoparticle delivery platform that utilizes a dual mechanism of action of anti-tumor angiogenesis and pro-tumor apoptosis, which provides a robust and potent strategy for the delivery of anti-cancer therapeutics.
文摘四川西部地区地理环境复杂,滑坡空间结构多样且变形剧烈。为有效预防滑坡灾害,需要探究相关区域滑坡危险性可靠评价方法。利用G1-熵权耦合赋权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS)构建滑坡灾害危险性评价模型,选取高程、降雨、地震动参数等12个评价因子,对雅砻江滑坡灾害危险性进行评价。依据贴近度将滑坡区域分为4个等级,即高危险区(0.75~1)、较高危险区(0.5~0.75)、中等危险区(0.25~0.5)和低危险区(0~0.25)。同时,对比了由差分干涉测量短基线集时序分析(small baseline subset interferometric synthetic aperture radar,SBAS-InSAR)技术得到的4个区域滑坡实测结果和本文评价模型的分析结果。利用G1-熵权耦合赋权TOPSIS得到九龙县烟袋镇桤木林村高生地滑坡、新龙县和平乡甲西村麻西滑坡、德格县年古乡政府滑坡和甘孜县扎科乡达玛滑坡的贴近度分别为0.854、0.686、0.405和0.224,由SBAS-InSAR技术得到滑坡前缘局部变形速率分别为-150、-43、-66、30 mm/a,二者之间有显著的对应关系,证明本文评价模型的准确性。应用G1-熵权耦合赋权TOPSIS法对滑坡危险性评价具有较高的准确性,该方法可为其他地区滑坡地质灾害评价提供参考。
文摘随着5G技术的不断发展,5G蜂窝网络已被广泛应用于城市地区。然而,基于5G的机会信号定位技术中存在着测距精度不高的问题。针对此问题,提出一种改进型5G机会信号定位算法,该算法将多信号分类(multiple signal classification,MUSIC)算法与改进的早-晚功率锁相环(phase-locked loop,PLL)结合,不仅简化了锁相环结构,更保证了测距精度;同时搭建了基于5G机会信号定位的原理样机,并对改进算法方法的有效性和可行性进行了验证,试验结果表明伪距均方误差为3.03 m。本文所提出的算法不仅结构简单、系统稳定,而且在测距精度上也有一定的优势。
