Background:Dementia is a group of nervous system diseases characterized by progressive cognitive decline,leading to a loss of self-care ability and a decline in well-being.This places a significant burden on the globa...Background:Dementia is a group of nervous system diseases characterized by progressive cognitive decline,leading to a loss of self-care ability and a decline in well-being.This places a significant burden on the global healthcare system,with Chinese patients accounting for approximately one-quarter of the world’s dementia cases.Therefore,it is crucial to identify factors that impact the quality of life(QOL)among elderly Chinese individuals with dementia.Method:To achieve this,we conducted a comprehensive search of several databases,including PubMed,Embase,Web of Science,the Cochrane Library,China National Knowledge Infrastructure,Wanfang Data,China VIP Database and China Biomedical Literature Database.We reviewed cross-sectional studies from the inception of these databases until March 27,2022.QOL outcomes were assessed using standardized scales in the studies included in this review.Results:The search yielded a total of 1,235 relevant articles,from which we finally included 21 cross-sectional studies and one longitudinal study after rigorous quality assessment.Among these,10 studies were classified as high quality,while 12 were classified as fair quality.Through our analysis,we identified 28 patient-rated QOL factors and 14 caregiver-rated QOL factors.These factors were categorized into three groups:patient,disease-related and caregiver.Factors commonly found to influence patient-rated QOL included age,education,marital status,depression,self-care ability,dementia severity,cognitive function,behavioral and psychological symptoms of dementia and caregiver burden.Similarly,factors commonly influencing caregiver-rated QOL included economic status,depression,self-care ability,dementia severity,cognitive function,behavioral and psychological symptoms of dementia and caregiving time.Conclusion:This review clarifies the factors that influence the QOL of Chinese individuals with dementia.When implementing interventions,it is crucial to consider the differences between patient-rated QOL and caregiver-proxy-rated QOL,as well as their respective influencing factors.展开更多
Objective To introduce the accession procedure and evaluation of PIC/S,and help relevant departments in China to understand the requirements of PIC/S in detail,and to promote the process of China’s entry into PIC/S.M...Objective To introduce the accession procedure and evaluation of PIC/S,and help relevant departments in China to understand the requirements of PIC/S in detail,and to promote the process of China’s entry into PIC/S.Methods The procedures and steps of joining PIC/S,the evaluation process of PIC/S,and the experience of several countries in joining PIC/S were introduced and analyzed,which could help the relevant personnel in China understand the specific contents.Results and Conclusion According to the requirements of PIC/S,it is necessary to establish a unified GMP quality management system.展开更多
Background: Deep brain stimulation (DBS) is an established treatment for patients with advanced Parkinson’s disease (PD). Reports show continued patient satisfaction after surgery despite not maintaining clinical imp...Background: Deep brain stimulation (DBS) is an established treatment for patients with advanced Parkinson’s disease (PD). Reports show continued patient satisfaction after surgery despite not maintaining clinical improvement as measured by evolution scales. Objectives: The present study sought to explore expectations and level of satisfaction in patients after DBS surgery with a semi-structured questionnaire and subsequent correlation with functional scales, Quality of Life (QoL), and motor and non-motor symptoms. Methods: We performed descriptive statistics to represent demographic data, Wilcoxon rank tests to determine significant differences, and Spearman correlation between the applied scales. Results: We evaluated 20 patients with a history of DBS surgery. 45% were female, with a mean age of 55.7 ± 14.15 years, a mean disease duration of 13.42 ± 8.3 years, and a mean time after surgery of 3.18 ± 1.86 years. Patients reported surgery meeting expectations in 85.5% and continued satisfaction in 92%. These two variables showed a significant correlation. Conclusions: This sample of patients remained satisfied after DBS surgery, although we found no differences in motor and non-motor clinimetric scales. Further studies are needed to confirm the importance of assessing quality of life in patients with DBS.展开更多
为了提高电能质量扰动(power quality disturbance,PQD)识别结果的准确性,笔者提出一种基于改进灰狼优化算法(improved grey wolf optimization,IGWO)优化最小二乘支持向量机(least squares support vector machine,LSSVM)的PQD识别方...为了提高电能质量扰动(power quality disturbance,PQD)识别结果的准确性,笔者提出一种基于改进灰狼优化算法(improved grey wolf optimization,IGWO)优化最小二乘支持向量机(least squares support vector machine,LSSVM)的PQD识别方法。通过采用收敛因数指数调整、自适应位移和权重动态修订等措施对灰狼优化算法进行改进,得到IGWO算法;以PQD信号的9个特征量为支持向量、7种PQD类型为输出量,利用IGWO算法寻找LSSVM的最优参数,建立基于IGWO-LSSVM的PQD识别模型并进行仿真分析,且与其他模型的识别结果进行对比。结果表明,相比算例中列出的几种对比模型,IGWO-LSSVM模型识别结果的正确率更高,验证了所提PQD识别方法的有效性和实用性。展开更多
The major phytoplankton was investigated and analyzed in landscape water of six campuses in Nanjing Xianlin University Town,and water quality was evaluated by single factor assessment method and comprehensive weighted...The major phytoplankton was investigated and analyzed in landscape water of six campuses in Nanjing Xianlin University Town,and water quality was evaluated by single factor assessment method and comprehensive weighted evaluation method.The result showed that the major phytoplankton groups were Cyanophyta,Chlorophyta and Bacillariophyta.Besides,each evaluation indicator showed that waterbodies in four campuses were eutrophicated and result of single factor evaluation showed water quality all belonged to poor category V.The result of comprehensive weighted assessment showed that waters in Nanjing Normal University and Nanjing University of Posts and Telecommunications were seriously polluted,cyanobacterial bloom appearing.Waters in Nanjing University of Chinese Medicine and Nanjing Forest Police College hadn't been eutrophicated.展开更多
文摘Background:Dementia is a group of nervous system diseases characterized by progressive cognitive decline,leading to a loss of self-care ability and a decline in well-being.This places a significant burden on the global healthcare system,with Chinese patients accounting for approximately one-quarter of the world’s dementia cases.Therefore,it is crucial to identify factors that impact the quality of life(QOL)among elderly Chinese individuals with dementia.Method:To achieve this,we conducted a comprehensive search of several databases,including PubMed,Embase,Web of Science,the Cochrane Library,China National Knowledge Infrastructure,Wanfang Data,China VIP Database and China Biomedical Literature Database.We reviewed cross-sectional studies from the inception of these databases until March 27,2022.QOL outcomes were assessed using standardized scales in the studies included in this review.Results:The search yielded a total of 1,235 relevant articles,from which we finally included 21 cross-sectional studies and one longitudinal study after rigorous quality assessment.Among these,10 studies were classified as high quality,while 12 were classified as fair quality.Through our analysis,we identified 28 patient-rated QOL factors and 14 caregiver-rated QOL factors.These factors were categorized into three groups:patient,disease-related and caregiver.Factors commonly found to influence patient-rated QOL included age,education,marital status,depression,self-care ability,dementia severity,cognitive function,behavioral and psychological symptoms of dementia and caregiver burden.Similarly,factors commonly influencing caregiver-rated QOL included economic status,depression,self-care ability,dementia severity,cognitive function,behavioral and psychological symptoms of dementia and caregiving time.Conclusion:This review clarifies the factors that influence the QOL of Chinese individuals with dementia.When implementing interventions,it is crucial to consider the differences between patient-rated QOL and caregiver-proxy-rated QOL,as well as their respective influencing factors.
文摘Objective To introduce the accession procedure and evaluation of PIC/S,and help relevant departments in China to understand the requirements of PIC/S in detail,and to promote the process of China’s entry into PIC/S.Methods The procedures and steps of joining PIC/S,the evaluation process of PIC/S,and the experience of several countries in joining PIC/S were introduced and analyzed,which could help the relevant personnel in China understand the specific contents.Results and Conclusion According to the requirements of PIC/S,it is necessary to establish a unified GMP quality management system.
文摘Background: Deep brain stimulation (DBS) is an established treatment for patients with advanced Parkinson’s disease (PD). Reports show continued patient satisfaction after surgery despite not maintaining clinical improvement as measured by evolution scales. Objectives: The present study sought to explore expectations and level of satisfaction in patients after DBS surgery with a semi-structured questionnaire and subsequent correlation with functional scales, Quality of Life (QoL), and motor and non-motor symptoms. Methods: We performed descriptive statistics to represent demographic data, Wilcoxon rank tests to determine significant differences, and Spearman correlation between the applied scales. Results: We evaluated 20 patients with a history of DBS surgery. 45% were female, with a mean age of 55.7 ± 14.15 years, a mean disease duration of 13.42 ± 8.3 years, and a mean time after surgery of 3.18 ± 1.86 years. Patients reported surgery meeting expectations in 85.5% and continued satisfaction in 92%. These two variables showed a significant correlation. Conclusions: This sample of patients remained satisfied after DBS surgery, although we found no differences in motor and non-motor clinimetric scales. Further studies are needed to confirm the importance of assessing quality of life in patients with DBS.
文摘为了提高电能质量扰动(power quality disturbance,PQD)识别结果的准确性,笔者提出一种基于改进灰狼优化算法(improved grey wolf optimization,IGWO)优化最小二乘支持向量机(least squares support vector machine,LSSVM)的PQD识别方法。通过采用收敛因数指数调整、自适应位移和权重动态修订等措施对灰狼优化算法进行改进,得到IGWO算法;以PQD信号的9个特征量为支持向量、7种PQD类型为输出量,利用IGWO算法寻找LSSVM的最优参数,建立基于IGWO-LSSVM的PQD识别模型并进行仿真分析,且与其他模型的识别结果进行对比。结果表明,相比算例中列出的几种对比模型,IGWO-LSSVM模型识别结果的正确率更高,验证了所提PQD识别方法的有效性和实用性。
基金Supported by National Foundation for Fostering Talents in Basic Science(J0730650)~~
文摘The major phytoplankton was investigated and analyzed in landscape water of six campuses in Nanjing Xianlin University Town,and water quality was evaluated by single factor assessment method and comprehensive weighted evaluation method.The result showed that the major phytoplankton groups were Cyanophyta,Chlorophyta and Bacillariophyta.Besides,each evaluation indicator showed that waterbodies in four campuses were eutrophicated and result of single factor evaluation showed water quality all belonged to poor category V.The result of comprehensive weighted assessment showed that waters in Nanjing Normal University and Nanjing University of Posts and Telecommunications were seriously polluted,cyanobacterial bloom appearing.Waters in Nanjing University of Chinese Medicine and Nanjing Forest Police College hadn't been eutrophicated.
