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Gangrene of the External Genitalia at Chu-Abeche
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作者 Vadandi Valentin Mahamat Ali Mahamat +5 位作者 Abdelmahamoud Chene Vounouzia Barthelemy Temga Ouang Michael Minguemadji Allah Siyangar Ndormadjita Allah Siyangar Rimtebaye Kimassoum 《Open Journal of Urology》 2024年第4期197-206,共10页
Introduction: Gangrene of the external genitalia organs (EGO) is a medico-surgical emergency that is still very common in Third World countries. The main etiologies are urogenital, dermocutaneous and proctological. Mo... Introduction: Gangrene of the external genitalia organs (EGO) is a medico-surgical emergency that is still very common in Third World countries. The main etiologies are urogenital, dermocutaneous and proctological. Mortality remains very high despite therapeutic advances. Our aim was to report on the epidemiological, diagnostic and therapeutic aspects of gangrene of the external genitalia, and to identify prognostic factors. Patients and Method: This was a 5-year retrospective descriptive study, from February 2016 to February 2021, of cases of gangrene of the external genitalia admitted to and treated in the Urology Department of Abeche University Hospital. Results: We collected 49 cases of gangrene of the external genitalia. The mean age of patients was 42 ± 16.81, with extremes of 20 and 81 years. The age group most concerned was between 20 and 29. The most frequent reasons for consultation were suppuration of the external genitalia and scrotal swelling. The average consultation time was 19.05 ± 16.02 days. The most common comorbidity was diabetes (35.9%). The most frequent pathological antecedents were urinary tract infections and endourethral maneuvers, reported in 40.5% and 38.7% respectively. Urogenital aetiology was predominant in 54.7%, and idiopathic in 35.9%. Lesions involved the scrotum in 60.6%, the scrotum and penis in 16.5%, and the penis alone in 5.7% of cases. Lesions extended to the perineum in 13.6% of cases, and to the abdomen in 3.6%. Vascular filling via the central venous line was performed in 58.6% of cases, and via the peripheral venous line in 41.4%. 3rd-generation cephalosporins and associated imidazoles were the most commonly used antibiotics. Necrosectomy was performed in 37 patients (73.4%), debridement combined with bypass cystostomy in 26.6% of cases. Colostomy was performed in 4% of cases. 90.8% of patients were cured and 9.2% died. The average hospital stay was 30 ± 75 days. Conclusion: The gangrene of the external genitalia is a medical and surgical emergency which has become rare in Europe, but which is still very common in the context of our practice in Chad. The severity of the disease is linked to delayed consultation and co-morbidity factors. Mortality remains very high despite therapeutic advances. 展开更多
关键词 GANGRENE External genitalia Medical and Surgical Treatment
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Damage to the External Genitalia by Traction Following Assault and Battery at the C.H.U Gabriel Touré: About a Case
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作者 Karembé Boubacar Traoré Boureima +13 位作者 Tounkara Idrissa Diarra Issaka Coulibaly Mamadou Tidiani Soumaré Modibo Dianguina Coulibaly Abdoulaye Camara Aboubacar Touré Aboubacar Sanogo Seydou Fall Ibrahim Diakité Mané Diarra Mouminy Traoré Abdoulaye Diarra Drissa Diakité Mamadou Lamine 《Surgical Science》 2023年第2期55-60,共6页
Trauma to the external genitalia by tearing is rare. We report the case of a 30-year-old patient, admitted to the emergency room for trauma of the external genitalia by traction following a blow and intentional injury... Trauma to the external genitalia by tearing is rare. We report the case of a 30-year-old patient, admitted to the emergency room for trauma of the external genitalia by traction following a blow and intentional injury. The authors highlight the lesions that can occur during this type of trauma and insist on the systematic search for urethral and cavernous lesions. Conclusion: Trauma to the external genitalia by intentional assault and battery is rare in our context. They occur most often in a young person and are frequently associated with damage to the corpora cavernosa and urethra. 展开更多
关键词 TRAUMA External genitalia TRACTION
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Differential diagnosis of ambiguous genitalia in Chinese patients 被引量:5
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作者 Tian Qinjie(田秦杰) +1 位作者 Ge Qinsheng(葛秦生) 《生殖医学杂志》 CAS 2002年第z1期38-41,共4页
Objective: To study the etiology and differential diagnos is of ambiguous genitalia.Methods: One hundred and five cases of ambiguous genitalia with disorders of sexual differentiation were analyzed based on clinical c... Objective: To study the etiology and differential diagnos is of ambiguous genitalia.Methods: One hundred and five cases of ambiguous genitalia with disorders of sexual differentiation were analyzed based on clinical characterist ics and basic research. Results: Ambiguous genitalia are closely related to the functio n of androgen. It could be classified into 3 groups: androgen excess, androgen d eficiency and failure of gonadal differentiation. Differential diagnosis depends on clinical manifestations, chromosome examination, serum hormone determination s, final gonadal pathology, receptor study etc.Conclusion: Ambiguous genitalia are related to abnormal androgen ic effect and early correct etiological diagnosis is the key to its management. 展开更多
关键词 AMBIGUOUS genitalia ANDROGEN CHROMOSOME
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Recent Injuries of External Genitalia: Clinical Aspects and Management
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作者 Kimassoum Rimtebaye Kaboro Mignagnal +3 位作者 Arya Zarif Agah Tashkand Franklin Danki Sillong Lamine Niang Gueye Serigne Magueye 《Open Journal of Urology》 2015年第9期161-166,共6页
Aim: Report the epidemiological, clinicopathological characteristics and ensuring management of recent traumas of the external genitalia in Urology. Methods: This was a descriptive retrospective study of 47 cases of p... Aim: Report the epidemiological, clinicopathological characteristics and ensuring management of recent traumas of the external genitalia in Urology. Methods: This was a descriptive retrospective study of 47 cases of patients suffering from recent traumas of the external genitalia over a period of 5 years. The variables studied were sociodemographic, clinical, paraclinical, therapeutic and evolutionary. Results: A total of 47 patients, including 46 men, were managed. The mean age was 26.8 years, ranging from 6 to 56 years. The circumstances of occurrence were: the missteps of coitus (n = 16), traffic accidents (n = 9) and criminal injuries (n = 8). The fracture of the penis (n = 16) was the most common lesion followed by the scrotal wound (n = 11). The management was medical and surgical and varied by the type of lesion. The outcome was favorable in 91.5% of cases. Conclusion: The incidence of traumas of the external genitalia was 9.4 in urology department in N'Djamena. Penis fracture was the frequent lesion. The management is multidisciplinary, medical and surgical. 展开更多
关键词 COITUS SCROTUM PENIS External genitalia UROLOGY
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Contribution of the Medical Imaging in Care of Ambiguous Genitalia
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作者 Zanga Sore Moussa Diallo Ousseini +3 位作者 Ouattara Boubakar Napon Aischa Madina Bamouni Yomboue Abel Cisse Rabiou 《Open Journal of Radiology》 2018年第2期125-130,共6页
We report a case of ambiguous genitalia in a 15-year-old patient to demonstrate input of medical imaging in the diagnosis and care of this rare congenital deformation. Disorders of sexual differentiation (DSD) have be... We report a case of ambiguous genitalia in a 15-year-old patient to demonstrate input of medical imaging in the diagnosis and care of this rare congenital deformation. Disorders of sexual differentiation (DSD) have been defined as congenital conditions in which development of chromosome, gonad, or anatomic sex is atypical and that raise an issue in the sex assignment. In lower socioeconomic countries where antenatal diagnosis is almost non-existent, due to lack of technical facilities, their medical and surgical management is hard. The case which we report was investigated by ultrasonography and genitography, which remains primary indications in our context. 展开更多
关键词 AMBIGUOUS genitalia KARYOTYPE ULTRASONOGRAPHY Genitography
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External Genitalia Gangrene: Clinical, Therapeutic Aspects and Prognosis at University Hospital Souro Sanou of Bobo Dioulasso (Burkina Faso)
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作者 Timothée Kambou Adama Ouattara +4 位作者 Abdoulkarim Paré Brahima Kirakoya Fasnéwindé Aristide Kaboré Hassan Dogo Hamidou Bako 《Open Journal of Urology》 2017年第12期235-242,共8页
Objective: To describe the clinical aspects and the management of external genitalia gangrene in the Urology department of the Bobo Dioulasso CHUSS. Patients and methods: This was a retrospective and descriptive study... Objective: To describe the clinical aspects and the management of external genitalia gangrene in the Urology department of the Bobo Dioulasso CHUSS. Patients and methods: This was a retrospective and descriptive study over a period of 6 years from January 2011 to December 2016, which covered 54 patients hospitalized in the urology department of the University Hospital Souro Sanou for external genitalia gangrene. Results: The mean age of our patients was 53.8 years. The large ulcero-necrosis of scrotum was the main reason for reference. Our patients consulted on average 8.23 days after the onset of symptomatology. A risk factor was found in 44.2% of cases and a cause was identified in 65.3% of patients. A urogenital cause was present in 32.7%. Probabilistic antibiotic therapy and medical reanimation were systematic at admission. Debridement was performed on average 18 hours after admission and 10 patients had more than one debridement. We noted a mortality rate of 5.5%. Conclusion: Fournier’s gangrene is a serious infectious disease whose diagnosis is often delayed in our context. Early surgical debridement remains the essential therapeutic gesture to reduce mortality. 展开更多
关键词 GANGRENE EXTERNAL genitalia DEBRIDEMENT
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Severe External Genitalia Lesion by Firearm: A Case Report
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作者 Mahamat Ali Mahamat Sidi Sougui +4 位作者 Choua Ouchemi Olivier Ngaringuem Mohamed Jalloh Lamine Niang Serigne M. Gueye 《Open Journal of Urology》 2015年第10期188-191,共4页
Gunshot wounds to external genitalia are rare either in war field and civilian setting accounting for 2% - 4% of all injuries with often a lesion to the urinary tract. We report a case of external genital injury in a ... Gunshot wounds to external genitalia are rare either in war field and civilian setting accounting for 2% - 4% of all injuries with often a lesion to the urinary tract. We report a case of external genital injury in a 27 years old man, accidentally injured by his own arm when he pressed the trigger of his gun placed in his pants. He had no past medical or surgical history, he presented to the emergency room (ER) with hemorrhagic scrotal and penile injuries with adjacent urethral tissue damage. He underwent a scrotal flap urethroplasty, and realignment of the corpus cavernosa and the tunica albugina. The patient lost his Foley catheter at post-operative day 3 and subsequently developed a urethral stenosis. Gunshot wounds to external genitalia are rare. A good reconstruction is necessary to avoid an impact on sexual and voiding function. 展开更多
关键词 TRAUMA External genitalia GUNSHOT
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Management of Trauma to the External Genitalia at the Nianankoro-Fomba Hospital in Segou Mali
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作者 Sory Ibrahim Koné Abdoulaye Kassogué +11 位作者 Brehima Samaké Mahamoudou Keita Tidiani Traore Abdoulaye Nouhoum Coulibaly Mamadou Adama Togo Thierno Boubacar Bagayoko Adama Bah Aminata Fofana Alpha Sanogo Damissa Coulibaly Sidi Modibo Doucouré Honoré Jean Gabriell Berthé 《Open Journal of Urology》 2022年第6期376-382,共7页
Trauma to the male genitalia is not very common and mainly affects a young population. There is probably a particular instinct in men to defend their external genitalia;indeed, in the flaccid state, the penis is littl... Trauma to the male genitalia is not very common and mainly affects a young population. There is probably a particular instinct in men to defend their external genitalia;indeed, in the flaccid state, the penis is little exposed, and fairly well protected and its mobility allows it to move with the impact of trauma and thus reduce the vulnating force. Open trauma is rare, as is testicular dislocation, the most common being closed trauma. Testicular trauma is an uncommon accident that affects young people. Trauma is most often caused by road and traffic accidents. Animal bites are rare, as is genital self-mutilation related to a psychiatric disorder. Surgical exploration is the rule except in cases of moderate testicular trauma. Our objective was to report our experience in an emergency context where treatment is poorly codified and to review the literature. We recorded four patients with external genitalia trauma managed in the urology department from April 2013 to March 2022. Our patients were children with open genitalia trauma following a traffic accident, scrotal injuries were encountered in three patients, and additional penile injuries in one patient. All patients were treated surgically. The follow-up was straightforward. 展开更多
关键词 TRAUMA genitalia OPEN Segou
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Trauma of External Genitalia by Firearm: Therapeutic Strategy and Result, about a Case at CHU-YO, Ouagadougou, Burkina Faso
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作者 Clôtaire Alexis Marie Kiemdiba Donega Yameogo Brahima Kirakoya +4 位作者 Moussa Kaboré Fasnéwindé A. Kaboré Bienvenue D. Ky Boukary Kabré Barnabé Zango 《Open Journal of Urology》 2016年第4期63-66,共4页
Introduction: Ballistic traumas of the external genitalia are rare especially in civil practice. Emergency surgical exploration is the rule. Case Report: Mr. F.Y., 29 years old, a security agent, admitted to the Urolo... Introduction: Ballistic traumas of the external genitalia are rare especially in civil practice. Emergency surgical exploration is the rule. Case Report: Mr. F.Y., 29 years old, a security agent, admitted to the Urological Emergency Unit of Yalgado Ouédraogo University Hospital of Ouagadougou for trauma of the penile and left purse by firearm. The clinical examination revealed a good hemodynamic status, bladder distension. A suprapubic catheterization was performed. We noted a transfixing and bleeding wound on the penile, and on the left purse which was edematous. The patient was admitted to the operation room 07 hours after trauma. Exploration found a total destruction of the left testicle classified grade 5 of the classification of the American Association of the Surgery of Trauma (AAST). We performed a left orchiectomy. There was a partial rupture of the ventral face of the penile urethra. We performed an end-to-end anastomosis on a Foley catheter CH 18. The Foley catheter was removed after two weeks. Urination was spontaneous without dysuria. Erections were painless and without kinking of penile. Conclusion: Open traumas of the external genitalia are rare and their treatment is an extreme surgical emergency. 展开更多
关键词 TRAUMA External genitalia FIREARMS Emergency
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妇科点阵式二氧化碳激光治疗幼女外阴硬化性苔藓护理个案管理
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作者 周艳 赵春梅 +2 位作者 关心怡 孙小丽 龙璐璐 《实用妇科内分泌电子杂志》 2024年第18期115-117,共3页
目的探讨点阵式二氧化碳激光治疗幼女外阴硬化性苔藓的个案护理体会。方法选取1例行点阵式二氧化碳激光治疗外阴硬化性苔藓幼女,在激光治疗前后护理的同时,做好患儿家属对患儿居家照料的健康宣教。结果患儿在二氧化碳激光治疗期间能配... 目的探讨点阵式二氧化碳激光治疗幼女外阴硬化性苔藓的个案护理体会。方法选取1例行点阵式二氧化碳激光治疗外阴硬化性苔藓幼女,在激光治疗前后护理的同时,做好患儿家属对患儿居家照料的健康宣教。结果患儿在二氧化碳激光治疗期间能配合各项操作,点阵式二氧化碳激光治疗后外阴皮肤灼热感缓解、瘙痒感缓解、居家护理照料到位,无并发症发生。结论针对临床行点阵式二氧化碳激光治疗硬化性苔藓的患儿,护理人员进行系统化护理个案管理,对患儿进行心理护理、健康教育、居家照料指导及随访追踪等护理措施,取得患儿及家属的支持配合,使点阵式二氧化碳激光治疗顺利进行,正确处理治疗后的不良反应,无发生相关治疗并发症。 展开更多
关键词 点阵式二氧化碳激光 外阴硬化性苔藓 个案管理
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为害小麦新害虫——显脉污灯蛾Spilarctia bisecta Leech (Lepidoptera: Arctiidae)
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作者 秦杨 余金珂 +1 位作者 刘怀 王梓英 《植物保护》 CAS CSCD 北大核心 2024年第1期347-355,共9页
小麦是我国三大粮食作物之一,其在生产过程中受到多种害虫为害;在调查重庆市潼南区小麦病虫害过程中新发现一种鳞翅目害虫为害小麦,对其进行形态学及细胞色素氧化酶Ⅰ亚基(cytochrome oxidaseⅠ,COⅠ)基因序列鉴定,确定其为显脉污灯蛾Sp... 小麦是我国三大粮食作物之一,其在生产过程中受到多种害虫为害;在调查重庆市潼南区小麦病虫害过程中新发现一种鳞翅目害虫为害小麦,对其进行形态学及细胞色素氧化酶Ⅰ亚基(cytochrome oxidaseⅠ,COⅠ)基因序列鉴定,确定其为显脉污灯蛾Spilarctia bisecta Leech。污灯蛾属中有多种为害农作物的害虫,但显脉污灯蛾在中国还未有为害小麦的确切报道,这一发现提醒我们应当注意小麦和其他禾本科作物上的潜在害虫。 展开更多
关键词 小麦 显脉污灯蛾 形态学鉴定 外生殖器 细胞色素氧化酶I亚基
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下尿路和外生殖器战创伤及其诊疗研究进展
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作者 杨国荣 吕凯凯 +2 位作者 吴洋洋 宋涛 袁清 《解放军医学杂志》 CAS CSCD 北大核心 2024年第3期335-342,共8页
近年来,随着现代战争模式、武器及防护装备的不断革新,战创伤的发生机制、模式发生了很大变化。防弹衣及简易爆炸装置的广泛使用使泌尿生殖系统战创伤发生率逐渐升高,且泌尿生殖系统战创伤的模式也发生了改变,即从内部结构(肾脏、输尿... 近年来,随着现代战争模式、武器及防护装备的不断革新,战创伤的发生机制、模式发生了很大变化。防弹衣及简易爆炸装置的广泛使用使泌尿生殖系统战创伤发生率逐渐升高,且泌尿生殖系统战创伤的模式也发生了改变,即从内部结构(肾脏、输尿管、膀胱)转移到外部结构(阴囊、睾丸、阴茎、尿道),提示应将泌尿生殖系统战创伤的研究重点逐渐转移到下尿路及外生殖器创伤。本文就数次现代战争中泌尿生殖系统战创伤的发生率、治疗以及预后进行综述,主要阐述下尿路及外生殖器战创伤相关情况及其诊疗的相关进展。 展开更多
关键词 泌尿生殖系统损伤 下尿路 外生殖器 战创伤 诊疗
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外阴溃疡与女性内分泌激素水平的关系研究 被引量:1
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作者 华晓蕾 王芸 张会申 《实用妇科内分泌电子杂志》 2024年第15期34-36,共3页
目的探讨外阴溃疡与女性内分泌激素水平之间的关系。方法选取本院收治的30例外阴溃疡女性患者作为观察组,并以同期健康体检的27例女性作为对照组。对两组的雌激素、雄激素、孕激素和催乳素水平进行检测,采用Logistic二元回归分析对相关... 目的探讨外阴溃疡与女性内分泌激素水平之间的关系。方法选取本院收治的30例外阴溃疡女性患者作为观察组,并以同期健康体检的27例女性作为对照组。对两组的雌激素、雄激素、孕激素和催乳素水平进行检测,采用Logistic二元回归分析对相关激素水平与外阴溃疡的相关性进行分析,并通过受试者工作曲线(ROC曲线)对多因素分析结果在外阴溃疡中的诊断价值进行分析。结果观察组雌二醇、睾酮、孕酮、催乳素水平均低于对照组(P<0.05)。雌二醇和睾酮指标低是女性发生外阴溃疡的危险因素(P<0.05)。ROC曲线结果中,雌二醇的曲线下面积为0.878(P<0.05),睾酮的曲线下面积为0.882(P<0.05)。结论女性外阴溃疡发生可能受到其内分泌激素,尤其是雌二醇和睾酮分泌的影响,在实施治疗的时候有必要针对这两项指标进行把握和调节,以增强女性外阴组织细胞的修复和增殖能力,提升免疫力,防范外阴溃疡的发生。 展开更多
关键词 外阴溃疡 女性 内分泌激素 关系
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甘肃酒泉地区十二种蝗虫雄性外生殖器比较研究
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作者 王兴铎 郑成卓 +3 位作者 董子信 刘恒亮 付连海 钱秀娟 《昆虫学报》 CAS CSCD 北大核心 2024年第9期1239-1250,共12页
【目的】为了准确鉴定甘肃酒泉地区草地蝗虫种类,明确蝗虫雄性外生殖器在分类中的关键特征及指标。【方法】通过解剖比较研究了采自甘肃酒泉草地的12种蝗虫成虫雄性外生殖器结构,分属3科7属,具体为:斑腿蝗科(Catantopidae)稻蝗属Oxya中... 【目的】为了准确鉴定甘肃酒泉地区草地蝗虫种类,明确蝗虫雄性外生殖器在分类中的关键特征及指标。【方法】通过解剖比较研究了采自甘肃酒泉草地的12种蝗虫成虫雄性外生殖器结构,分属3科7属,具体为:斑腿蝗科(Catantopidae)稻蝗属Oxya中华稻蝗Oxya chinensis和无齿稻蝗O.adentata;斑翅蝗科(Oedipodidae)小车蝗属Oedaleus红胫小车蝗Oedaleus manjius和黄胫小车蝗O.infernalis,尖翅蝗属Epacromius大垫尖翅蝗Epacromius coerulipes和小垫尖翅蝗E.tergestinus tergestinus,束颈蝗属Sphingonotus宁夏束颈蝗Sphingonotus ningsianus和盐池束颈蝗S.yenchihensis,胫刺蝗属Compsorhipis大胫刺蝗Compsorhipis davidiana;网翅蝗科(Arcypteridae)雏蝗属Chorthippus华北雏蝗Chorthippus brunneus huabeiensis和白纹雏蝗C.albonemus,异爪蝗属Euchorthippus素色异爪蝗Euchorthippus unicolor,并对雄性外生殖器的8项指标进行主成分分析。【结果】斑腿蝗科稻蝗属阳具基背片桥狭,且无锚状突,阳具复合体色带连片较宽,其余10种蝗虫阳具基背片桥宽,均具锚状突,阳具复合体色带连片较窄;斑翅蝗科阳具复合体阳茎基瓣宽圆形,而网翅蝗科阳具复合体阳茎基瓣为钩状;冠突的形状在各属之间变化显著。12种蝗虫雄性外生殖器8项指标的主成分分析结果表明,特征值大于1.00的有2个主成分,即第1主成分和第2主成分;第1主成分的主要组分包括锚状突外侧间距、后突外侧间距、锚状突内侧间距、锚状突高、两锚状突间距和桥宽,第2主成分的主组分为阳具复合体长宽比,两者总贡献率为78.27%。【结论】蝗虫的雄性外生殖器在科、属、种之间具有明显的差异,可以用雄性外生殖器准确区分酒泉地区12种草地蝗虫;区分这12种蝗虫时,锚状突的相对位置、后突间距、桥宽和阳具复合体的大小是主要指标。 展开更多
关键词 直翅目 蝗总科 蝗虫 分类 形态 雄性外生殖器 主成分分析
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CO_(2)点阵激光技术治疗外阴硬化性苔藓的临床研究 被引量:1
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作者 钟宝雁 朱洁云 +3 位作者 温佳丽 余琳 颜依雅 张素玉 《实用妇科内分泌电子杂志》 2024年第7期52-54,58,共4页
目的探究CO_(2)点阵激光技术在外阴硬化性苔藓治疗中的临床效果。方法选择本院60例外阴硬化性苔藓病变患者为研究对象,采用随机数字表法分为试验组和对照组,每组30例。对照组采用糖皮质激素+中成药泡洗,试验组采用CO_(2)点阵激光治疗。... 目的探究CO_(2)点阵激光技术在外阴硬化性苔藓治疗中的临床效果。方法选择本院60例外阴硬化性苔藓病变患者为研究对象,采用随机数字表法分为试验组和对照组,每组30例。对照组采用糖皮质激素+中成药泡洗,试验组采用CO_(2)点阵激光治疗。比较两组治疗前后外阴瘙痒、皮肤颜色、裂口、性交疼痛变化评分,评估临床疗效及复发时间。结果治疗后,两组外阴瘙痒、皮肤颜色和性交疼痛评分均低于治疗前,且试验组低于对照组(P<0.05)。试验组治疗总有效率高于对照组(P<0.05)。结论CO_(2)点阵激光治疗外阴硬化性苔藓患者临床疗效较好,能显著改善患者的外阴瘙痒、皮肤颜色和性交疼痛等症状,可视为外阴硬化性苔藓的一种有效治疗手段,值得在临床进一步推广与应用。 展开更多
关键词 多元聚焦激光技术 外阴硬化性苔藓 临床治疗
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人工牛黄甲硝唑胶囊致男性患者外生殖器多形红斑型药疹的诊疗分析
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作者 初丽娟 吴涛 王蓉华 《抗感染药学》 2024年第2期136-138,共3页
目的:分析1例人工牛黄甲硝唑胶囊致男性患者外生殖器多形红斑型药疹的诊疗过程,为临床该药的用药安全提供参考。方法与结果:该患者因牙痛而自行购买人工牛黄甲硝唑胶囊服用,但第2天患者发现外生殖器不行米粒至豆粒大小的红斑,呈密集对... 目的:分析1例人工牛黄甲硝唑胶囊致男性患者外生殖器多形红斑型药疹的诊疗过程,为临床该药的用药安全提供参考。方法与结果:该患者因牙痛而自行购买人工牛黄甲硝唑胶囊服用,但第2天患者发现外生殖器不行米粒至豆粒大小的红斑,呈密集对称分布,伴轻微瘙痒,遂自行停药;但停药多日后仍未见好转,皮损还逐渐增大,且表面出现糜烂、渗出,遂入院治疗;入院后,对患者予以了抗炎、抗感染治疗,2周后患者红斑基本消失,1个月后患者皮损也基本痊愈;其间,医生采用诺氏评估量表考察多形红斑型药疹与人工牛黄甲硝唑胶囊的关联性,结果评分为6分,即关联性为“很可能”。结论:人工牛黄甲硝唑胶囊所致药疹仅出现在外生殖器部位而未涉及身体其他部位的情况较为罕见,临床在宣教时应做好用药交代,以便于患者早分辨、早治疗。 展开更多
关键词 人工牛黄甲硝唑胶囊 男性患者 外生殖器 多形红斑型药疹 药物不良反应
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TRPS1在原发性乳腺外Paget病中的表达及其诊断价值
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作者 毛学源 戚玉琴 +3 位作者 佘欣远 黄旭 郑宇 王前玉 《诊断病理学杂志》 2024年第9期851-854,共4页
目的分析TRPS1在原发性乳腺外Paget病(EMPD)中的表达情况,探讨TRPS1在原发性EMPD诊断中的价值。方法收集宿迁市第一人民医院病理科2015年7月至2023年12月诊断的39例原发性EMPD、6例继发性EMPD、15例黑色素瘤和11例鳞状细胞原位癌病历资... 目的分析TRPS1在原发性乳腺外Paget病(EMPD)中的表达情况,探讨TRPS1在原发性EMPD诊断中的价值。方法收集宿迁市第一人民医院病理科2015年7月至2023年12月诊断的39例原发性EMPD、6例继发性EMPD、15例黑色素瘤和11例鳞状细胞原位癌病历资料,采用免疫组织化学En Vision法检测TRPS1的表达情况。结果原发性EMPD患者39例,男性29例,女性10例;年龄53~81岁(平均年龄68岁,中位年龄71岁)。继发性EMPD患者6例,男性4例,女性2例;年龄45~76岁(平均年龄59岁,中位年龄62.5岁)。39例原发性EMPD中,35例(35/39)显示TRPS1强和弥漫的细胞核表达,阳性率为89.7%,且4例阴性病例均位于肛周;而在6例继发性EMPD中均为阴性。TRPS1在15例黑色素瘤中也呈阴性,在90.9%(10/11)的鳞状细胞原位癌中表现为弥漫强阳性。本组病例中,TRPS1诊断原发性EMPD的敏感性和特异性分别为89.7%和68.8%。结论TPRS1在原发性EMPD中的表达具有高敏感性,有助于与继发性EMPD和黑色素瘤进行鉴别,但在原发性EMPD与鳞状细胞原位癌的鉴别中作用有限。 展开更多
关键词 乳腺外PAGET病 免疫组织化学 TRPS1 外生殖器 腋窝
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结核感染T细胞斑点试验诊断女性生殖器结核的价值
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作者 王翠荣 孙林林 《中国卫生标准管理》 2024年第15期35-38,共4页
目的探讨结核抗体检测(tuberculosis antibody testing,TB-Ab)与结核感染T细胞斑点试验(T-cell spot of tuberculosis,T-SPOT.TB)诊断女性生殖器结核(female genital tuberculosis,FGT)的临床价值。方法选取2021年1月—2023年12月济宁... 目的探讨结核抗体检测(tuberculosis antibody testing,TB-Ab)与结核感染T细胞斑点试验(T-cell spot of tuberculosis,T-SPOT.TB)诊断女性生殖器结核(female genital tuberculosis,FGT)的临床价值。方法选取2021年1月—2023年12月济宁市公共卫生医疗中心收治的82例临床初诊怀疑FGT的患者为研究对象。分别采用TB-Ab和T-SPOT.TB对患者进行检查,统计阳性检出率。以子宫内膜病理检查结果为“金标准”,评价2项诊断技术对FGT的诊断效能。结果基于“金标准”,TB-Ab诊断FGT的敏感度、特异度与准确率分别为69.10%、72.73%、69.51%,T-SPOT.TB诊断FGT的敏感度、特异度与准确率分别为91.55%、90.91%、91.46%,TB-Ab联合T-SPOT.TB诊断FGT的敏感度、特异度与准确率分别为94.37%、90.91%、93.90%。T-SPOT.TB诊断FGT的敏感度与准确率均高于TB-Ab,差异有统计学意义(P<0.05);TB-Ab联合T-SPOT.TB诊断FGT的敏感度与准确率高于TB-Ab单一诊断,差异有统计学意义(P<0.05),但与T-SPOT.TB诊断比较,差异无统计学意义(P>0.05)。结论T-SPOT.TB对FGT的诊断效能高于TB-Ab,更具临床应用价值。 展开更多
关键词 女性 生殖器 结核 结核抗体检测 结核感染T细胞斑点试验 诊断效能
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中药熏蒸联合氦氖激光用于外阴白色病变的临床效果研究
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作者 邹勇健 谢春花 曾琦 《黑龙江医药》 CAS 2024年第1期54-57,共4页
目的:分析中药熏蒸联合氦氖激光在外阴白色病变患者中的效果。方法:选取2021年7月—2023年7月信丰县妇幼保健院收治的68例外阴白色病变患者,按随机数字表法分为两组,各34例。对照组行氦氖激光治疗,观察组加以中药熏蒸治疗,1个月为1个疗... 目的:分析中药熏蒸联合氦氖激光在外阴白色病变患者中的效果。方法:选取2021年7月—2023年7月信丰县妇幼保健院收治的68例外阴白色病变患者,按随机数字表法分为两组,各34例。对照组行氦氖激光治疗,观察组加以中药熏蒸治疗,1个月为1个疗程,持续治疗3个疗程。对比两组临床疗效、症状改善情况、生活质量、复发率。结果:观察组治疗总有效率高于对照组,外阴痒、阴痛、皮肤弹性、色素脱失改善时间短于对照组,有统计学差异(P<0.05);治疗前,两组生活质量综合评定问卷(GQOLI-74)内各维度评分相比,无统计学差异(P>0.05);治疗后,观察组GQOLI-74内各维度评分高于对照组,有统计学差异(P<0.05)。随访3个月,观察组复发率低于对照组,有统计学差异(P<0.05)。结论:中药熏蒸联合氦氖激光能够减轻外阴白色病变患者症状,提高生活质量,减少复发。 展开更多
关键词 外阴白色病变 中药熏蒸 氦氖激光 生活质量 复发 色素脱失
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Comparative morphology study of the male genitalia in the tribe Astathini from China(Coleoptera:Cerambycidae)
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作者 Si-Yao He Li Chen Zhi-Ping Liu 《Zoological Systematics》 CSCD 2015年第2期197-211,共15页
The male genitalia of 13 species from four genera of Astathini were described and analyzed. The result showed that five genital characters, such as shape of the apex of 8th abdominal tergaum and sternum, ratio of the ... The male genitalia of 13 species from four genera of Astathini were described and analyzed. The result showed that five genital characters, such as shape of the apex of 8th abdominal tergaum and sternum, ratio of the length of lateral lobes to tegmen, can be used to identify genera of Astathini; six characters, such as ratio of the length of lateral lobes to tegmen, ratio of the length of roof to lateral lobes, shape of the apex of ventral plate of median lobe, can be used to identify species in Bacchisa. 展开更多
关键词 Astathini Bacchisa male genitalia comparative morphology China.
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