原发性纵隔大B细胞淋巴瘤(primary mediastinal large B-cell lymphoma,PMBCL)是弥漫性大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)的一种特殊亚型,好发于年轻女性[1-2]。PMBCL是一种罕见的癌症,目前对复发/难治性PMBCL的治疗...原发性纵隔大B细胞淋巴瘤(primary mediastinal large B-cell lymphoma,PMBCL)是弥漫性大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)的一种特殊亚型,好发于年轻女性[1-2]。PMBCL是一种罕见的癌症,目前对复发/难治性PMBCL的治疗一般与其他复发/难治性DLBCL治疗相同,治疗方案主要包括:R-DA-EPOCH(利妥昔单抗+依托泊苷+泼尼松+长春新碱+环磷酰胺+阿霉素),DHAP(地塞米松+阿糖胞苷+顺铂),ESHAP(依托泊苷+甲基强的松+阿糖胞苷+铂剂),GDP(吉西他滨+地塞米松+顺铂),以及mini-beam(卡莫司汀+依托泊苷+阿糖胞苷+马法兰)[3-4]。展开更多
Three group velocity dispersion (GVD) compensation schemes, i.e., the post-compensation, pre-compensation and hybrid-compensation schemes, are discussed with considering polarization mode dispersion (PMD). In the 10- ...Three group velocity dispersion (GVD) compensation schemes, i.e., the post-compensation, pre-compensation and hybrid-compensation schemes, are discussed with considering polarization mode dispersion (PMD). In the 10- and 40-Gbit/s non-return-zero (NRZ) on-off-key (OOK) systems, three physical factors, Kerr effect, GVD and PMD are considered. The numerical results show that, when the impact of PMD is taken into account, the GVD pre-compensation scheme performs best with more than 1 dB better of average eye-opening penalty (EOP) when input power is up to 10 dBm in the 10-Gbit/s system. However the GVD post-compensation scheme performs best for the case of 40 Gbit/s with input power less than 13 dBm, and GVD pre-compensation will be better if the input power increased beyond this range. The results are different from those already reported under the assumption that the impact of PMD is neglected. Therefore, the research in this paper provide a different insight into the system optimization when PMD, Kerr effect and GVD are considered.展开更多
广义Voronoi图(GVD)的生成可以分为直接法和近似法.利用VDC(Van Der Corput)采样序列,结合了近似法,设计了一种基于VDC采样序列的GVD生成算法.该算法改进了一般生成GVD的近似方法,使得点集的采样可以增量进行,并且精度可控,提高了现有GV...广义Voronoi图(GVD)的生成可以分为直接法和近似法.利用VDC(Van Der Corput)采样序列,结合了近似法,设计了一种基于VDC采样序列的GVD生成算法.该算法改进了一般生成GVD的近似方法,使得点集的采样可以增量进行,并且精度可控,提高了现有GVD生成算法的性能.展开更多
文摘原发性纵隔大B细胞淋巴瘤(primary mediastinal large B-cell lymphoma,PMBCL)是弥漫性大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)的一种特殊亚型,好发于年轻女性[1-2]。PMBCL是一种罕见的癌症,目前对复发/难治性PMBCL的治疗一般与其他复发/难治性DLBCL治疗相同,治疗方案主要包括:R-DA-EPOCH(利妥昔单抗+依托泊苷+泼尼松+长春新碱+环磷酰胺+阿霉素),DHAP(地塞米松+阿糖胞苷+顺铂),ESHAP(依托泊苷+甲基强的松+阿糖胞苷+铂剂),GDP(吉西他滨+地塞米松+顺铂),以及mini-beam(卡莫司汀+依托泊苷+阿糖胞苷+马法兰)[3-4]。
基金This work was supported by National High Technology Development Program of China (No. 2001AA122012 and No. 2001AA120205). A. Yang's e-mail address is qiaoyay@water.pku.edu.cn.
文摘Three group velocity dispersion (GVD) compensation schemes, i.e., the post-compensation, pre-compensation and hybrid-compensation schemes, are discussed with considering polarization mode dispersion (PMD). In the 10- and 40-Gbit/s non-return-zero (NRZ) on-off-key (OOK) systems, three physical factors, Kerr effect, GVD and PMD are considered. The numerical results show that, when the impact of PMD is taken into account, the GVD pre-compensation scheme performs best with more than 1 dB better of average eye-opening penalty (EOP) when input power is up to 10 dBm in the 10-Gbit/s system. However the GVD post-compensation scheme performs best for the case of 40 Gbit/s with input power less than 13 dBm, and GVD pre-compensation will be better if the input power increased beyond this range. The results are different from those already reported under the assumption that the impact of PMD is neglected. Therefore, the research in this paper provide a different insight into the system optimization when PMD, Kerr effect and GVD are considered.