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A Comparison of New General System Theory Philosophy With Einstein and Bohr
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作者 CUI Weicheng LI Rong PAN Lingli 《Journal of Philosophy Study》 2023年第1期1-22,共22页
The New General System theory was developed to be a theory of everything for complex systems within the world we can observe.This theory was constructed by supplementing a new mind-ether ontology into Bertalanffy’s g... The New General System theory was developed to be a theory of everything for complex systems within the world we can observe.This theory was constructed by supplementing a new mind-ether ontology into Bertalanffy’s general system theory framework.This theory is basically a generalization of classical mechanics rather than a revolution to it taken both by Einstein and Bohr in developing their relativity theory and quantum mechanics.The purpose of this paper is to reveal the reasons why Einstein and many others fail to unify relativity theory with quantum mechanics through comparing the main differences in philosophical opinions among NGST,Einstein,and Bohr.It is the hope of the authors that this clarification could speed up the unification process. 展开更多
关键词 complex system(CS) New general system Theory(NGST) theory of everything(TOE) classical mechanics(CM) relativity theory(RT) quantum mechanics(QM) Bohmian Mechanics(BM) active force entanglement of minds
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On the Philosophical Ontology for a General System Theory 被引量:7
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作者 CUI Weicheng 《Journal of Philosophy Study》 2021年第6期443-458,共16页
System is a very general concept and theoretically speaking, every problem encountered can be modeled as a system. Thus, the general system theory (GST) proposed by Bertalanffy (1968) and developed by many others e.g.... System is a very general concept and theoretically speaking, every problem encountered can be modeled as a system. Thus, the general system theory (GST) proposed by Bertalanffy (1968) and developed by many others e.g. Bunge (1977;1979;1983a;1983b) and Maturana and Varela (1980;1987) could be treated as a theory of everything (TOE). However, it is well-known that the present version of GST has not reached the level of TOE because it lacks a clear ontology. Currently, quantum mechanics (QM), Newtonian mechanics (NM) and general relativity (GR), suitable for microscopic, macroscopic and cosmic phenomena respectively are based on very different ontologies. In this paper, a unified ontology for the general system theory which could be applied to any scale from micro to cosmic is proposed. It is expected that this could lay a foundation to generalize GST to TOE. 展开更多
关键词 system general system theory PHILOSOPHY METAPHYSICS ONTOLOGY MATTER MIND aether
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Re-examination of the Two-Body Problem Using Our New General System Theory 被引量:3
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作者 PAN Lingli CUI Weicheng 《Journal of Philosophy Study》 2021年第12期891-913,共23页
It is well-known that philosophical conflicts exist among classical mechanics,quantum mechanics and relativistic mechanics.In order to use the framework of general system theory to unify these three mechanics subjects... It is well-known that philosophical conflicts exist among classical mechanics,quantum mechanics and relativistic mechanics.In order to use the framework of general system theory to unify these three mechanics subjects,a new general system theory is developed based on a new ontology of ether and minds as the fundamental existences in the world.The two-body problem is the simplest model in mechanics and in this paper,it is re-examined by using our new general system theory.It is found that the current description of the classical full two-body problem is inappropriate since the observer and the measurement apparatus have not been explicitly considered.After considering these,it is actually a three-body problem while only the special case of the Kepler problem is the two-body problem.By introducing the concepts of psychic force and psychic field,all the possible movement states in the two-body problem can be explained within the framework of classical mechanics.There is no need to change the meanings of many fundamental concepts,such as time,space,matter,mass,and energy as done in quantum mechanics and relativity theory.This points out a new direction for the unification of different theories. 展开更多
关键词 two-body problem new general system theory gravitational field psychic field classical mechanics quantum mechanics relativity theory
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On the Trajectory Prediction of a Throwing Object Using New General System Theory
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作者 CUI Weicheng 《Journal of Philosophy Study》 2022年第2期53-64,共12页
Trajectory prediction for the movement of a given object is one of the main tasks for the classical mechanics but in orthodox quantum mechanics,this task was announced to be an impossibility for the(sub-)atomic partic... Trajectory prediction for the movement of a given object is one of the main tasks for the classical mechanics but in orthodox quantum mechanics,this task was announced to be an impossibility for the(sub-)atomic particles by famous Heisenberg’s uncertainty principle.Of course,such an epistemology is against the philosophical beliefs of many scientists and currently another version of trajectory quantum mechanics known as Bohmian mechanics also exists.In order to unify the conflicts among classical mechanics,quantum mechanics,and relativity theory,a new general system theory(NGST)was proposed by the present author and his colleagues.The purpose of this paper is to demonstrate that it is not the scale that matters but the living nature whether the object is lifeless or living.By using the psychic force concept introduced in NGST,Newton’s second law is applied to analyze five different types of objects.They are a stone,a coin,a cat,a person,and an electron.It is found that the classical mechanics has provided adequate room to explain the various newly observed phenomena for orthodox quantum mechanics and relativity theory and for human beings various parapsychological phenomena can also be explained by classical mechanics.Therefore,it is concluded that generalization of classical mechanics is adequate and no need to develop revolutionary quantum mechanics and relativity theory. 展开更多
关键词 object type TRAJECTORY new general system theory gravitational field psychic field classical mechanics quantum mechanics
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Complexity Decision Making and General Systems Theory: An Educational Perspective
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作者 M. Kudret Yurtseven Walter W. Buchanan 《Sociology Study》 2016年第2期77-95,共19页
The aim of this paper is to look at some important educational aspects of complexity decision making m a mummsc^pnnary manner from the perspective of General Systems Theory (GST). First, the major issues involved in... The aim of this paper is to look at some important educational aspects of complexity decision making m a mummsc^pnnary manner from the perspective of General Systems Theory (GST). First, the major issues involved in complexity management and decision making are summarized as they are viewed in literature, and a review of GST and Systems Thinking is given. The discussion in the paper is developed within the context of GST in general, but concentrated on decision making in the three trends of GST: Operations Research, Cybernetics, and Managerial Cybernetics. Here, the role of Cybernetics in complexity decision making is particularly emphasized. The discussion is then extended to the latest developments in complexity decision making in Science of Complexity and Soft Systems Thinking. The study also includes a framework which is expected to guide instructors who are planning to offer contemporary courses on decision making. The framework provides some clues for assessing the level of complexity for a given situation and selecting the appropriate methodology for solution development. 展开更多
关键词 Complexity decision making general systems Theory (GST) CYBERNETICS science of complexity soft systems thinking
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APPLICATION OF GENERAL SYSTEM CAD ON ENGINES
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作者 蒋炎坤 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 1998年第1期54-58,共5页
Using modern design theory and methods comprehensively, this paper investigates a model of parameterization of engine general plan design (PEGPD). On the basis of engineering database, parametric drawing of longitudi... Using modern design theory and methods comprehensively, this paper investigates a model of parameterization of engine general plan design (PEGPD). On the basis of engineering database, parametric drawing of longitudinal and cross section of engine can be obtained from this mode. The model is significant for improving the efficiency and quality of engine general system design. (Author abstract) 6 Refs. 展开更多
关键词 Computer Aided Design diesel engine general engineering database parametric drawing
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A NOTE ON THE GENERAL STABILIZATION OF DISCRETE FEEDBACK CONTROL FOR NON-AUTONOMOUS HYBRID NEUTRAL STOCHASTIC SYSTEMS WITH A DELAY
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作者 冯立超 张春艳 +1 位作者 曹进德 武志辉 《Acta Mathematica Scientia》 SCIE CSCD 2024年第3期1145-1164,共20页
Discrete feedback control was designed to stabilize an unstable hybrid neutral stochastic differential delay system(HNSDDS) under a highly nonlinear constraint in the H_∞ and exponential forms.Nevertheless,the existi... Discrete feedback control was designed to stabilize an unstable hybrid neutral stochastic differential delay system(HNSDDS) under a highly nonlinear constraint in the H_∞ and exponential forms.Nevertheless,the existing work just adapted to autonomous cases,and the obtained results were mainly on exponential stabilization.In comparison with autonomous cases,non-autonomous systems are of great interest and represent an important challenge.Accordingly,discrete feedback control has here been adjusted with a time factor to stabilize an unstable non-autonomous HNSDDS,in which new Lyapunov-Krasovskii functionals and some novel technologies are adopted.It should be noted,in particular,that the stabilization can be achieved not only in the routine H_∞ and exponential forms,but also the polynomial form and even a general form. 展开更多
关键词 hybrid neutral stochastic differential delay system discrete feedback control general stabilization polynomial stabilization
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General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain 被引量:1
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作者 Wen-Xin Hang Yan-Chang Yang +7 位作者 Yu-Han Hu Fu-Quan Fang Lang Wang Xing-Hua Qian Patrick M.McQuillan Hui Xiong Jian-Hang Leng Zhi-Yong Hu 《Zoological Research》 SCIE CSCD 2024年第3期691-703,共13页
General anesthetic agents can impact brain function through interactions with neurons and their effects on glial cells.Oligodendrocytes perform essential roles in the central nervous system,including myelin sheath for... General anesthetic agents can impact brain function through interactions with neurons and their effects on glial cells.Oligodendrocytes perform essential roles in the central nervous system,including myelin sheath formation,axonal metabolism,and neuroplasticity regulation.They are particularly vulnerable to the effects of general anesthetic agents resulting in impaired proliferation,differentiation,and apoptosis.Neurologists are increasingly interested in the effects of general anesthetic agents on oligodendrocytes.These agents not only act on the surface receptors of oligodendrocytes to elicit neuroinflammation through modulation of signaling pathways,but also disrupt metabolic processes and alter the expression of genes involved in oligodendrocyte development and function.In this review,we summarize the effects of general anesthetic agents on oligodendrocytes.We anticipate that future research will continue to explore these effects and develop strategies to decrease the incidence of adverse reactions associated with the use of general anesthetic agents. 展开更多
关键词 OLIGODENDROCYTES general anesthetic agents NEUROTOXICITY Central nervous system Perioperative neurocognitive disorders
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Extended wet sieving method for determination of complete particle size distribution of general soils 被引量:1
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作者 Shengnan Ma Yi Song +2 位作者 Jiawei Liu Xingyu Kang Zhongqi Quentin Yue 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期242-257,共16页
The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general soil.This paper extends the traditional meth... The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general soil.This paper extends the traditional method and presents an extended wet sieving method.The extended method uses both the steel sieves and the nylon filter cloth sieves.The apertures of the cloth sieves are smaller than 0.063 mm and equal 0.048 mm,0.038 mm,0.014 mm,0.012 mm,0.0063 mm,0.004 mm,0.003 mm,0.002 mm,and 0.001 mm,respectively.The extended method uses five steps to separate the general soil into many material sub-groups of gravel,sand,silt and clay with known particle size ranges.The complete PSD of the general soil is then calculated from the dry masses of the individual material sub-groups.The extended method is demonstrated with a general soil of completely decomposed granite(CDG)in Hong Kong,China.The silt and clay materials with different particle size ranges are further examined,checked and verified using stereomicroscopic observation,physical and chemical property tests.The results further confirm the correctness of the extended wet sieving method. 展开更多
关键词 Particle size distribution(PSD) general soil SILT CLAY Wet sieving Physical and chemical properties
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How to Make Systems of Nonlinear Autonomous ODEs with Attractor-Behavior, by First Making the General Solutions: Part Two
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作者 Magne Stensland 《Journal of Applied Mathematics and Physics》 2023年第1期115-134,共20页
This paper is presenting a new method for making first-order systems of nonlinear autonomous ODEs that exhibit limit cycles with a specific geometric shape in two and three dimensions, or systems of ODEs where surface... This paper is presenting a new method for making first-order systems of nonlinear autonomous ODEs that exhibit limit cycles with a specific geometric shape in two and three dimensions, or systems of ODEs where surfaces in three dimensions have attractor behavior. The method is to make the general solutions first by using the exponential function, sine, and cosine. We are building up the general solutions bit for bit according to constant terms that contain the formula of the desired limit cycle, and differentiating them. In Part One, we used only formulas for closed curves where all parts of the formula were of the same degree. In order to use many other formulas for closed curves, the method in this paper is to introduce an additional variable, and we will get an additional ODE. We will choose the part of the formula with the highest degree and multiply the other parts with an extra variable, so that all parts of the formula have the same degree, creating a constant term containing this new formula. We will place it under the fraction line in the solutions, building up the rest of the solutions according to this constant term and differentiating. Keeping this extra variable constant, we will achieve almost the desired result. Using the methods described in this paper, it is possible to make some systems of nonlinear ODEs that are exhibiting limit cycles with a distinct geometric shape in two or three dimensions and some surfaces having attractor behavior, where not all parts of the formulas are the same degree. The pictures show the result. 展开更多
关键词 system of Nonlinear ODEs Limit Cycle general Solution ATTRACTOR
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A nonlocal dispersal and time delayed HIV infection model with general incidences
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作者 WU Peng ZHANG Yu-huai WANG Ling 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第3期448-457,共10页
Biologically,because of the impact of reproduction period and nonlocal dispersal of HIV-infected cells,time delay and spatial heterogeneity should be considered.In this paper,we establish an HIV infection model with n... Biologically,because of the impact of reproduction period and nonlocal dispersal of HIV-infected cells,time delay and spatial heterogeneity should be considered.In this paper,we establish an HIV infection model with nonlocal dispersal and infection age.Moreover,applying the theory of Fourier transformation and von Foerster rule,we transform the model to an integrodifferential equation with nonlocal time delay and dispersal.The well-posedness,positivity,and boundedness of the solution for the model are studied. 展开更多
关键词 HIV model nonlocal dispersal time delay general incidences
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Higher-order expansions of powered extremes of logarithmic general error distribution
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作者 TAN Xiao-feng LI Li-hui 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第1期47-54,共8页
In this paper,Let M_(n)denote the maximum of logarithmic general error distribution with parameter v≥1.Higher-order expansions for distributions of powered extremes M_(n)^(p)are derived under an optimal choice of nor... In this paper,Let M_(n)denote the maximum of logarithmic general error distribution with parameter v≥1.Higher-order expansions for distributions of powered extremes M_(n)^(p)are derived under an optimal choice of normalizing constants.It is shown that M_(n)^(p),when v=1,converges to the Frechet extreme value distribution at the rate of 1/n,and if v>1 then M_(n)^(p)converges to the Gumbel extreme value distribution at the rate of(loglogn)^(2)=(log n)^(1-1/v). 展开更多
关键词 logarithmic general error distribution convergence rate higher-order expansion powered ex-treme
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Image Steganography by Pixel-Value Differencing Using General Quantization Ranges
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作者 Da-Chun Wu Zong-Nan Shih 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第10期353-383,共31页
A new steganographic method by pixel-value differencing(PVD)using general quantization ranges of pixel pairs’difference values is proposed.The objective of this method is to provide a data embedding technique with a ... A new steganographic method by pixel-value differencing(PVD)using general quantization ranges of pixel pairs’difference values is proposed.The objective of this method is to provide a data embedding technique with a range table with range widths not limited to powers of 2,extending PVD-based methods to enhance their flexibility and data-embedding rates without changing their capabilities to resist security attacks.Specifically,the conventional PVD technique partitions a grayscale image into 1×2 non-overlapping blocks.The entire range[0,255]of all possible absolute values of the pixel pairs’grayscale differences in the blocks is divided into multiple quantization ranges.The width of each quantization range is a power of two to facilitate the direct embedding of the bit information with high embedding rates.Without using power-of-two range widths,the embedding rates can drop using conventional embedding techniques.In contrast,the proposed method uses general quantization range widths,and a multiple-based number conversion mechanism is employed skillfully to implement the use of nonpower-of-two range widths,with each pixel pair being employed to embed a digit in the multiple-based number.All the message bits are converted into a big multiple-based number whose digits can be embedded into the pixel pairs with a higher embedding rate.Good experimental results showed the feasibility of the proposed method and its resistance to security attacks.In addition,implementation examples are provided,where the proposed method adopts non-power-of-two range widths and employsmultiple-based number conversion to expand the data-hiding and steganalysis-resisting capabilities of other PVD methods. 展开更多
关键词 STEGANOGRAPHY pixel-value differencing multiple-based number conversion general quantization range
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Influencing factors and risk prediction model for emergence agitation after general anesthesia for primary liver cancer
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作者 Shu-Shu Song Li Lin +1 位作者 Li Li Xiao-Dong Han 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第7期2194-2201,共8页
BACKGROUND General anesthesia is commonly used in the surgical management of gastrointestinal tumors;however,it can lead to emergence agitation(EA).EA is a common complication associated with general anesthesia,often ... BACKGROUND General anesthesia is commonly used in the surgical management of gastrointestinal tumors;however,it can lead to emergence agitation(EA).EA is a common complication associated with general anesthesia,often characterized by behaviors,such as crying,struggling,and involuntary limb movements in patients.If treatment is delayed,there is a risk of incision cracking and bleeding,which can significantly affect surgical outcomes.Therefore,having a proper understanding of the factors influencing the occurrence of EA and implementing early preventive measures may reduce the incidence of agitation during the recovery phase from general anesthesia,which is beneficial for improving patient prognosis.AIM To analyze influencing factors and develop a risk prediction model for EA occurrence following general anesthesia for primary liver cancer.METHODS Retrospective analysis of clinical data from 200 patients who underwent hepatoma resection under general anesthesia at Wenzhou Central Hospital(January 2020 to December 2023)was conducted.Post-surgery,the Richmond Agitation-Sedation Scale was used to evaluate EA presence,noting EA incidence after general anesthesia.Patients were categorized by EA presence postoperatively,and the influencing factors were analyzed using logistic regression.A nomogram-based risk prediction model was constructed and evaluated for differentiation and fit using receiver operating characteristics and calibration curves.RESULTS EA occurred in 51(25.5%)patients.Multivariate analysis identified advanced age,American Society of Anesthesiologists(ASA)grade Ⅲ,indwelling catheter use,and postoperative pain as risk factors for EA(P<0.05).Conversely,postoperative analgesia was a protective factor against EA(P<0.05).The area under the curve of the nomogram was 0.972[95%confidence interval(CI):0.947-0.997]for the training set and 0.979(95%CI:0.951-1.000)for the test set.Hosmer-Lemeshow test showed a good fit(χ^(2)=5.483,P=0.705),and calibration curves showed agreement between predicted and actual EA incidence.CONCLUSION Age,ASA grade,catheter use,postoperative pain,and analgesia significantly influence EA occurrence.A nomogram constructed using these factors demonstrates strong predictive accuracy. 展开更多
关键词 Primary hepatocellular carcinoma resection general anesthesia Emergence agitation Risk factors FORECAST NOMOGRAPH
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Intelligent Transformation: General Intelligence Theory
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作者 Alexander Ngu Amaya Odilon Kosso 《International Journal of Intelligence Science》 2024年第3期59-70,共12页
This paper aims to formalize a general definition of intelligence beyond human intelligence. We accomplish this by re-imagining the concept of equality as a fundamental abstraction for relation. We discover that the c... This paper aims to formalize a general definition of intelligence beyond human intelligence. We accomplish this by re-imagining the concept of equality as a fundamental abstraction for relation. We discover that the concept of equality = limits the sensitivity of our mathematics to abstract relationships. We propose a new relation principle that does not rely on the concept of equality but is consistent with existing mathematical abstractions. In essence, this paper proposes a conceptual framework for general interaction and argues that this framework is also an abstraction that satisfies the definition of Intelligence. Hence, we define intelligence as a formalization of generality, represented by the abstraction ∆∞Ο, where each symbol represents the concepts infinitesimal, infinite, and finite respectively. In essence, this paper proposes a General Language Model (GLM), where the abstraction ∆∞Ο represents the foundational relationship of the model. This relation is colloquially termed “The theory of everything”. 展开更多
关键词 INTELLIGENCE generalIZATION ABSTRACTION TRANSFORMATION general Language Model general Intelligence Theory Theory of Everything
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Epidemiological, Clinical Aspects and Factors Associated with Typical Gastroesophageal Reflux Disease in the General Population of Parakou, Republic of Benin
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作者 Saké Khadidjatou Tamou Sambo Bio Elie +3 位作者 Zinsou Jocelyne Abla Dovonou Comlan Albert Sehonou Jean Kodjoh Nicolas 《Open Journal of Gastroenterology》 CAS 2024年第2期41-58,共18页
Introduction: Gastroesophageal reflux disease (GERD) is a benign and chronic disease that can impair the quality of life. Objective: To study the epidemiological, clinical aspects and factors associated with typical G... Introduction: Gastroesophageal reflux disease (GERD) is a benign and chronic disease that can impair the quality of life. Objective: To study the epidemiological, clinical aspects and factors associated with typical GERD in the general population of Parakou in the Republic of Benin. Methods: This was a descriptive and analytical cross-sectional study with prospective data collection which took place from May 1, 2019 to June 30, 2019. The study population consisted of any subject aged at least 15 years and living in Parakou. Subjects aged at least 15 years, present on the day of the survey and having given their free and informed verbal consent were included. The Short form of QRS®(Reflux-Qual Short form) questionnaire and the “Hospital Anxiety and Depression” score were used to assess the quality of life and anxiety/depression, respectively. The sampling was probabilistic through a 2-stage cluster sampling. The variable of interest was the presence of GERD. Results: Out of 390 subjects surveyed, 28 had symptoms of typical GERD, representing a prevalence of 7.18%. The average age of these subjects was 27.11 ± 7.88 years. Fifteen subjects (53.57%) were male, giving a sex ratio of 1.15. Fourteen (50%) had a secondary level of education, 12 (42.86%) were pupils/students, 18 (64.29%) were single. The monthly income of 22 subjects (78.57%) was lower than the guaranteed interprofessional minimum wage (40,000 FCFA). The average duration of progression of symptoms was 15.89 ± 4.97 months. Symptoms occurred less than twice a week in 22 subjects (78.57%). The clinical manifestations were both diurnal and nocturnal in 12 subjects (42.86%). None of the 28 subjects with GERD had clinical warning signs. Asthma, diabetes, consumption of high fat or spice foods, carbonated drinks, non-steroidal anti-inflammatory drugs, alcoholic beverages and tobacco were statistically associated with the occurrence of GERD. Each of the 28 subjects had at least one associated factor. A significant impair in quality of life was observed in 27 patients (96.43%). Conclusion: Typical GERD is relatively common in the general population of Parakou in the Republic of Benin. It often affects young males. Among the risk factors identified, the most common are carbonated drinks, spicy meals and diabetes. GERD significantly impairs quality of life. Raising awareness about the disease and its associated factors is necessary among the general population. 展开更多
关键词 Gastroesophageal Reflux Disease EPIDEMIOLOGY general Population Associated Factors Quality of Life Parakou
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Cost Control Strategies for Hubei General Highway Greening Project
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作者 ZHANG Qian HUANG Yaojun AN Yunhua 《Journal of Landscape Research》 2024年第4期17-20,共4页
In order to respond to the national policy of focusing on the service of building a new development pattern and promoting high-quality development,and to reduce the cost of greening projects while ensuring the effect ... In order to respond to the national policy of focusing on the service of building a new development pattern and promoting high-quality development,and to reduce the cost of greening projects while ensuring the effect of highway landscape,a process and cost control points of highway greening design,construction,and maintenance are summarized through a review of the literature.Additionally,this paper examines the attributes of highway greening and proposes cost control strategies that are aligned with these attributes.It is proposed that the implementation of cost control strategies for highway greening should commence at the project establishment phase,with the objective of establishing a comprehensive and effective cost management control system.While guaranteeing the greening landscape effect and the duration of the project,it is essential to regulate the crucial nodes in each phase of the design,construction,and maintenance process.Furthermore,it is vital to facilitate close collaboration between all parties involved,thereby reducing costs,conserving resources,and lowering energy consumption.This approach can also lead to enhanced economic and social benefits for highway greening projects. 展开更多
关键词 general highway Highway greening Greening project Cost control
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“Flow” Transcranial Direct Current Stimulation (tDCS) for Depression Treatment in a Primary Healthcare General Practice—An Open-Label Cohort Study Measuring Montgomery-Åsberg Depression Rating Scale (MADRS-S) Outcomes
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作者 Chris Griffiths Harmony Jiang +1 位作者 David Smart Azhar Zafar 《Open Journal of Psychiatry》 2024年第4期386-399,共14页
Background: Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application delivered wellbeing behaviour therapy training. tDCS... Background: Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application delivered wellbeing behaviour therapy training. tDCS has evidence of effectiveness in treating symptoms of depression. Purpose/Aim: This post marketing study evaluated the effect of Flow on depression for primary care general practice patients with depression symptoms. Methods: Open-label patient cohort design with no control group. Inclusion criteria were aged 18 years or over and reporting depression symptoms. Participants self-administered five 30 minute tDCS sessions per week for the first three weeks, and then 3 sessions per week following this. Three, six and ten week assessment with participant self-report measure: Montgomery- Åsberg Depression Rating Scale (MADRS-S). Results: MADRS-S remission rates were between 29% - 30% at three weeks, 33% - 34% at six-weeks and 50% at 10-weeks treatment. There was a significant improvement in MADRS-S with large effect sizes at all time points. Conclusions: Flow tDCS can be delivered through a primary healthcare general practice service and patients will choose to use. Flow tDCS provides an effective depression treatment in addition and as an alternative to antidepressants and psychotherapy. tDCS has evidence as an effective depression treatment, and the widespread availability of tDCS in primary care general practice should be considered. 展开更多
关键词 DEPRESSION Transcranial Direct Current Stimulation Wellbeing general Practice
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Postoperative Analgesia and Cesarean Section under General Anesthesia: Multicenter Study
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作者 Ghislain Edjo Nkilly Raphael Okoue Ondo +3 位作者 Pascal Christian Nze Obiang Stéphane Oliveira Jean-Marcel Mandji-Lawson Romain Tchoua 《Open Journal of Anesthesiology》 2024年第1期1-12,共12页
Background: Neuraxial anesthesia with intrathecal morphine is the reference technique in cesarean section anesthesia for the management of postoperative analgesia. If there is a contraindication to this, general anest... Background: Neuraxial anesthesia with intrathecal morphine is the reference technique in cesarean section anesthesia for the management of postoperative analgesia. If there is a contraindication to this, general anesthesia is required. The objective of the study was to evaluate the analgesic effectiveness of 4 analgesic techniques performed during cesarean section under general anesthesia in two centers with different anesthetic practices (North Franche Comté Hospital and Omar Bongo Ondimba Army Training Hospital). Method: This is a retrospective and descriptive study over 2 years, from January 1, 2019 to December 31, 2020. It involved evaluating the analgesic effectiveness and tolerance of morphine in the epidural catheter, wound infiltration, intravenous analgesia and Transversus Abdominous Plane block (TAP block) from the post-anesthesia care unit (PACU) until the 4<sup>th</sup> post-operative day. Results: Of the 354 cesarean sections performed, 84 (11.14%) received general anesthesia. The average age was 32.27 years. Acute fetal distress was the first indication for cesarean section (45.2%), followed by hemorrhagic placenta previa (10.7%) and prolapse of the cord (8.33%). Morphine in the epidural catheter was the most used (47.6%) followed by parietal infiltration (36.9%), intravenous analgesia (13.1%) and TAP block (2.38%). The analgesic effectiveness was comparable between the techniques from postoperative day 0 to day 4. No difference in side effects. Postoperative morphine consumption was significantly reduced (p = 0.011) in the infiltration (9 mg) and TAP block (9mg) groups compared to the epidural catheter (16 mg) and intravenous analgesia (17 mg). No difference in 02 rehabilitation criteria (ambulation, first bowel movement). No difference in the occurrence of chronic pain. Conclusion: In the event of a cesarean section under general anesthesia, there are effective and well-tolerated alternatives to neuraxial anesthesia, particularly regional anesthesia techniques (nerve blocks), particularly in countries with low availability of morphine. 展开更多
关键词 CESAREAN general Anesthesia MORPHINE Parietal Infiltration Epidural Catheter Transversus Abdominis Plane Block Intravenous Analgesia
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Pathological and Etiological Aspects of Nephrotic Syndrome at the Niamey General Reference Hospital
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作者 Djibrilla Gani Salamatou Amadou Niaouro Oumarou Ali Diallo 《Open Journal of Nephrology》 2024年第3期340-349,共10页
Introduction: Studies have been conducted on nephrotic syndrome in Niger. The study aimed to determine the histological and etiological aspects of nephrotic syndrome. Patients and Method: This was a retrospective stud... Introduction: Studies have been conducted on nephrotic syndrome in Niger. The study aimed to determine the histological and etiological aspects of nephrotic syndrome. Patients and Method: This was a retrospective study from February 1st, 2018 to January 31st, 2024. All patients with nephrotic syndrome who underwent renal biopsy were included. Samples were analyzed at the anatomy-cytology pathology laboratory of the Faculty of Medicine in Dakar (Senegal). The variables studied included clinical, biological, histological and etiological characteristics. Data were analyzed using Excel 2013 and Epi-info 7.2.0 software. Results: The study included 119 patients with nephrotic syndrome. Prevalence of nephrotic syndrome was 11.24%. The male-to-female ratio was 2.25:1. The mean age at diagnosis was between 34.5 ± 18.84 years. Edema was the reason for admission in 40.34% of cases. The nephrotic syndrome was impure in 63.86% of cases. Nine histological lesions were identified. Focal and segmental glomerulosclerosis (40.09%), minimal change disease (23.53%), membranous nephropathy (13.45%), diabetic nephropathy (10.92%), membranous proliferative glomerulonephritis (3.36%), acute glomerulonephritis (3.36%), glomerular thrombotic microangiopathy (2.52%), non-IgA mesengial proliferative glomerulonephritis (1.68%) and amyloidosis (0.84%). Nephrotic syndrome was primary in 57.98% of cases. Secondary etiologies were dominated by diabetes (11.76%), followed by hepatitis B virus (9.24%), lupus, lymphoma, malaria, syphilis, cryoglobulinemia, sickle cell disease and HIV. Conclusion: Future studies should investigate the causes of glomerulopathy secondary to chronic tubulointerstitial lesions. 展开更多
关键词 Nephrotic Syndrome Anatomopathology Niamey general Reference Hospital
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